Anaphylactoid nephritis is a disease complicated by anaphylactoid purpura manifested by a non-thrombocytopenic purpura, abdominal pain. And joint pain The manifestation of nephritis may vary from microscopic hematuria to acute rapidly progressive nephritic and nephrotic syndrome. This paper reports on anaphylactoid nephritis in children. These cases were collected fromthe Department of Pediatrics, Yonsei university Medical College from January 1,1974 to may 31, 1979. The results are as follows; 1. Among 75 cases of anaphylactoid purpura, 25 cases developed nephritis(33%), 16 cases were male and 9female. The age distribution was from 3years 5months to 15years. The peak incidence occured between 5 and 7years ofage with 11 cases. 2. The evidence of renal invovement in 18 cases among 25 were detected within 4 weeks after onset of skin manifestation. 3. The clinical manifestations were skin rashes, abdominal pain, joint pain, pitting edema, gross hematuria, and melena in orders. 4. The clinical classification of renal involvement were transient hematuria 4 cases, acute nephritis, 7 cases recurrent hematuria 1 case, nephrotic syndrome 5 cases, and undetermined 8 cases. 5. In additionto the usual signs of renal involvement, serum levels of IgA were checked. The elevation of IgA was 4 cases among the tested 6 cases. 6. According to the pathologic findings and immunofluorescent technique, 8 cases out of 9 cases by kidney biopsy were focal proliferative glomerulonephritis and 1 case diffuse proliferative flomerulonephritis. The deposit of glomeruli by immunofluorescent technique was IgA, IgG, IgM, and fibrin 7. All the cases were treated with prednisone and only 4 cases were combined with immunosuppressant, azathioprine without benfit.
Abdominal Pain ; Age Distribution ; Arthralgia ; Azathioprine ; Biopsy ; Child* ; Classification ; Edema ; Exanthema ; Fibrin ; Glomerulonephritis ; Hematuria ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Incidence ; Kidney ; Male ; Melena ; Nephritis ; Nephrotic Syndrome ; Pediatrics ; Prednisone ; Purpura ; Purpura, Schoenlein-Henoch ; Skin Manifestations

No abstract available.
Drug Therapy* ; Humans* ; Leukopenia*

We evaluated the one-stage intraoperative adjustment strabismus surgery with adjustable suture under topical anesthesia. Medical records of the patients who had intraoperative adjustment surgery under topical anesthesia for horizontal or vertical strabismus in our hospital from March 1997 to March 2003 with follow-up of 6 months were analyzed retrospectively. Of the 71 patients, 48 patients had exotropia, 16 had esotropia, and 7 had hyper- or hypotropia. The overall success rates were 85.9% at 1 week, 83% at 1 month, 78.9% at 3 months, and 76.1% at 6 months after surgery. The procedure was not stopped in any patients, and no serious intra-operative or postoperative complications were noted. Intraoperative adjustment strabismus surgery under topical anesthesia is a simple, well-tolerated and effective procedure.
Treatment Outcome ; *Suture Techniques ; Strabismus/*surgery ; Retrospective Studies ; Ophthalmologic Surgical Procedures/methods ; Middle Aged ; Male ; Intraoperative Period ; Humans ; Female ; Anesthetics, Local/administration & dosage ; Adult ; Adolescent ; Administration, Topical

This report documents a case of voluntary inhibition of acquired pendular nystagmus after head trauma. A 30-year-old male developed oscillopsia and decreased visual acuity, as well as findings of acquired pendular nystagmus with voluntary inhibition after head trauma. The EOG finding was horizontal 18-20Hz bilateral symmetrical pendular nystagmus in all directions of gaze at near and distant fixation. Nystagmus did not change with 14 Prism Diopter base-out prisms on both eyes, but it was possible to abolish it intentionally. Baclofen and Clonazepam had no effect in improving the patient's symptoms and EOG finding.
Adult ; Case Report ; Electrooculography ; GABA/physiology ; Human ; Male ; Nystagmus, Pathologic/*etiology/physiopathology ; gamma-Aminobutyric Acid/physiology

PURPOSE: In this study, we examined the incidence of osteoporosis and the related factors in distal radius fractures (DRFs) caused by minor trauma, as well as the necessity of a bone mineral density (BMD) measurement. MATERIALS AND METHODS: One hundred and sixty patients, who had their BMD measured after DRFs caused by minor trauma, were enrolled in this study. The BMD was measured at the lumbar spine and proximal femur by dual energy X-ray absorptiometry. The BMD values were categorized as normal, osteopenia and osteoporosis by the WHO T-score criteria and each incidence was investigated. The BMD values were compared with the change of age and among age-based groups. The relationship between the BMD and factors such as age, gender, body mass index, or AO classifi cation were assessed. The agreement in BMD values between the lumbar spine and proximal femur was evaluated. RESULTS: The incidence of osteoporosis in DFRs by minor trauma was 74%. The minimum BMD in the DRFs had a negative correlation with age. Signifi cant differences in the BMD values were observed between the groups divided by the 10-year-old intervals (p<0.001) but the differences in the groups aged over 60 were signifi cantly lower than those under the age of 60 (p<0.001). There was a close relationship between the BMD values and the patients' age (p<0.001), but not between the BMD values and the AO classifi cation (p=0.670). The simple agreement between the lumbar spine and proximal femur was 0.619, but the Kappa index was 0.305. CONCLUSION: Because the incidence of osteoporosis in the DRFs by minor trauma is relatively high, it is necessary to measure the BMD. The BMD should be measured at more than two body parts to ensure that osteoporosis accompanied by DRFs is not missed.
Absorptiometry, Photon ; Aged ; Body Mass Index ; Bone Density ; Bone Diseases, Metabolic ; Child ; Dietary Sucrose ; Femur ; Human Body ; Humans ; Incidence ; Osteoporosis ; Radius ; Radius Fractures ; Spine

Background/Aims: Although fecal microbiota transplantation (FMT) has been proven as one of the promising treatments for patients with ulcerative colitis (UC), potential prognostic markers regarding the clinical outcomes of FMT remain elusive. Methods: We collected fecal samples of 10 participants undergoing FMT to treat UC and those from the corresponding donors. We categorized them into two groups: responders and nonresponders. Sequencing of the bacterial 16S rRNA gene was conducted on the samples to explore bacterial composition. Results: Analyzing the gut microbiota of patients who showed different outcomes in FMT presented a distinct microbial niche. Source tracking analysis showed the nonresponder group had a higher rate of preservation of donor microbiota, underscoring that engraftment degrees are not one of the major drivers for the success of FMT. At the phylum level, Bacteroidetes bacteria were significantly depleted (p<0.003), and three genera, including Enterococcus, Rothia, and Pediococcus, were enriched in the responder group before FMT (p=0.003, p=0.025, and p=0.048, respectively). Furthermore, we applied a machine learning algorithm to build a prediction model that might allow the prediction of FMT outcomes, which yielded an area under the receiver operating characteristic (ROC) curve of 0.844. Notably, the microbiota-based model was much better at predicting outcomes than the clinical features model (area under the ROC curve=0.531). Conclusions This study is the first to suggest the significance of indigenous microbiota of recipients as a critical factor. The result highlights that bacterial composition should be evaluated before FMT to select suitable patients and achieve better efficiency.

The aim of the study was to evaluate the prevalence of restrictive ventilatory defect and to determine the risk factors in subjects with spirometrically-defined restrictive ventilatory defect. We used the population-based, fourth-2, 3 (2008, 2009) and fifth (2010-2012) Korea National Health and Nutrition Examination Survey (KNHANES) to analyze 15,073 subjects, aged > or =40 yr who underwent spirometry. Chest radiographs were also analyzed to identify restrictive lung disease. Spirometrically-defined restrictive ventilatory defect (FEV1/FVC> or =70% and FVC<80% of mean predicted value) was detected in 11.3% (n= 1,709) of subjects aged > or =40 yr. The prevalence increased to 12.3% on using the lower limit of normal (LLN) criteria. Approximately 99.4% of subjects were classified as mild restrictive. Among these, 11.3% had inactive tuberculosis (TB) lesion, 2.2% cardiac disease, 2.0% previous operation scar or radiation injury and/or mediastinal disease, and 7.4% other pulmonary disease suggestive of restrictive lung diseases on chest radiograph. Evidence of previous TB history was independently associated with restrictive ventilatory defect (odds ratios [OR], 1.78; 95% confidence interval, 1.45-2.18) after adjustment for gender, age, smoking, area for residence and body mass index. The prevalence of restrictive ventilatory defect among the nationwide population in Korea was 11.3% with fixed ratio criterion and 12.3% with LLN criterion. Most cases were of the mild restrictive category and previous TB history is the independent risk factor for restrictive ventilatory defect.
Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Educational Status ; Female ; Health Care Surveys ; Housing ; Humans ; Income ; Lung Diseases, Obstructive/*diagnosis/*epidemiology ; Male ; Middle Aged ; Prevalence ; Reproducibility of Results ; Republic of Korea/epidemiology ; Risk Factors ; Sensitivity and Specificity ; Sex Distribution ; Smoking/*epidemiology ; Spirometry/*statistics & numerical data