1.Comparison of Pain induced by injection of Local Anesthetic Solution warmed to Body Temperature versus at Room Temperature.
Soon Joo WANG ; Jae Hyung PARK ; Jae Myung CHUNG
Journal of the Korean Society of Emergency Medicine 1998;9(4):601-606
BACKGROUND: Infiltration of the skin and subcutaneous tissue with local anesthetic solutions may cause transient pain and discomfort. Heating local anesthetic solutions to body temperature has been suggested as a way of reducing the pain associated with injection. We designed a double blind crossover volunteer study to investigate the effect of warming lidocaine on the pain associated with subcutaneous injection. METHODS: Participants were 40 healthy adult volunteers,22 years of age and older, and they were the medical, nursing stay and medical students. They underwent 1ml subcutaneous injections of the study agent through 25-gauge needles. Following a standard crossover protocol, 'room temperature' lidocaine(20degrees C ) was injected into one midvolar forearm and body temperature' lidocaine(37degrees C ) into the opposite arm. Pain assessed by visual analogue pain scores and 'volunteer's comparison of pain on injection. RESULTS: Twenty-six volunteers thought that lidocaine at 20degrees C was more painful and four thought that lidocaine at 37degrees C was more painful, ten volunteers did not express a difference. Median pain score for injection at 20 degrees C was 37 and at 37 degrees C was 35.5. Difference of two median scores was 6.5. CONCLUSION: The simple procedure of warming to body temperature reduced the pain associated with subcutaneous injection of lidocaine. It is an inexpensive and practical method That should be considered for routine use in the ED.
Adult
;
Arm
;
Body Temperature*
;
Forearm
;
Heating
;
Hot Temperature
;
Humans
;
Injections, Subcutaneous
;
Lidocaine
;
Needles
;
Nursing
;
Skin
;
Students, Medical
;
Subcutaneous Tissue
;
Volunteers
2.Genotype and animal infectivity of a human isolate of Cryptosporidium parvum in the Republic of Korea.
Sang Mee GUK ; Tai Soon YONG ; Soon Jung PARK ; Jae Hwan PARK ; Jong Yil CHAI
The Korean Journal of Parasitology 2004;42(2):85-89
Cryptosporidium parvum oocysts were isolated from a child suffering from acute gastroenteritis and successfully passaged in a calf and mice (designated hereafter SNU-H1) in the Republic of Korea; its molecular genotype has been analyzed. The GAG microsatellite region was amplified by a polymerase chain reaction (PCR), with a 238 base pair product, which is commonly displayed in C. parvum. The isolate was shown to be a mixture of the genotypes 1 (anthroponotic) and 2 (zoonotic). To study its infectivity in animals, 2 calves and 3 strains of mice were infected with the SNU-H1; in these animals, the propagation of both genotypes was successful. In immunosuppressed (ImSP) BALB/c and C57BL/6 mice the number of oocysts decreased after day 10 post-infection (PI) ; but in ImSP ICR mice, they remained constant until day 27 PI. The results show that both the C. parvum genotypes 1 and 2 can be propagated in calves and ImSP mice.
Animals
;
Cattle
;
Child
;
Cryptosporidiosis/microbiology
;
Cryptosporidium parvum/*genetics/immunology
;
Diarrhea/parasitology
;
Feces/parasitology
;
Genotype
;
Human
;
Korea
;
Male
;
Mice
;
Mice, Inbred BALB C
;
Mice, Inbred C57BL
;
Mice, Inbred ICR
;
Oocysts
;
Polymerase Chain Reaction
;
Support, Non-U.S. Gov't
;
Zoonoses/parasitology
3.Intracranial metastases of lung cancer -CT and histopathologic correlation-.
Hyun Ju PARK ; Myung Soon KIM ; Myung Jae KANG
Journal of the Korean Radiological Society 1991;27(3):329-336
No abstract available.
Lung Neoplasms*
;
Lung*
;
Neoplasm Metastasis*
4.A new technique of corrective rhinoplasty for deflected bony dorsum.
Soon Jae YANG ; Kyu Yoon LEE ; Jong Sup PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(5):847-854
No abstract available.
Rhinoplasty*
5.Response and Toxicity of Chemotherapy in 78Cases of Malignant Ovarian Tumors.
Jae yeon WON ; Il Soo PARK ; Soon Gu HWANG
Korean Journal of Gynecologic Oncology and Colposcopy 1996;7(2):127-134
For evaluation of the response and toxicity of the combination chemotherapy, forty six patients with malignant ovarian tumors who had prior surgery were treated with combination chemotherapy from January 1985 to March 1991 at the Department of Obstetrics and Gynecology, Kyung-pook National University Hospital. The results were as follows : 1. The responses were in complete 20 cases(43.5%), in partial 9 cases(19,6%), in stable 6 cases(13.0%), in progressive 11 cases(23.9%) among 46 patients. 2. By the response rates of various combination chemotherapy regimens, the response rate of CAP was 64%(16/25), CP 57.1%(8/14), VAC 100%(3/3), VBP 50%(1/2), FAM 0%(0/1), and Melphalan 100%(1/1) respectively. 3. As the chemotoxicities of combination chemotherapy, leukopenia 20 cases(46.5%), thrombocytopenia 2 cases(4.7%), anemia 20 cases(46.5%), nephrotoxity 6 cases(14.6%), hepatotoxicity 7 cases(18.4%) were observed.
Anemia
;
Drug Therapy*
;
Drug Therapy, Combination
;
Gynecology
;
Humans
;
Leukopenia
;
Melphalan
;
Obstetrics
;
Thrombocytopenia
6.Steroid-Induced Glaucoma: Ten Cases Of Glaucoma Induced By Topical Corticosteroids.
Jae Ho KIM ; Sang Min KIM ; Yung Soon PARK
Journal of the Korean Ophthalmological Society 1969;10(3):33-39
No abstract available.
Adrenal Cortex Hormones*
;
Glaucoma*
7.Reduction rate and influencing factors of intussusception by hydrostatic water enema under ultrasound guidance and barium enema.
Jae Heum LEE ; Soon Ok CHOI ; Woo Hyun PARK
Journal of the Korean Surgical Society 1993;44(1):137-145
No abstract available.
Barium*
;
Enema*
;
Intussusception*
;
Ultrasonography*
;
Water*
8.Pregnancy following intra-tubal insemination in a woman who ovulated prior to gamete intra-fallopian transfer(GIFT).
Sang Bok LEE ; Jung Soon PARK ; Jae Seung LEE ; Seung Jae LEE ; Jong Min PARK
Korean Journal of Obstetrics and Gynecology 1991;34(5):747-749
No abstract available.
Female
;
Humans
;
Insemination*
;
Pregnancy*
9.Relationships among Ambulatory Plasma Renin Activity, Blood Pressure and Urinary Microalbumin Excretion Rate in Essential Hypertension.
In Soo PARK ; Ji Won PARK ; Bo In LEE ; Jae Yul SEO ; Jae Hyung KIM ; Soon Jo HONG
Korean Circulation Journal 1996;26(3):688-695
OBJECTIVE AND METHODS: To determine correlations among ambulatory renin activity, ambulatory blood pressure and microalbumin excretion rate, 66 Korean essential hypertensives were studied after 4 week wash-out period. The ambulatory blood pressure was monitored every 30 minutes and mean BP were calculated automatically. Urinary microalbumin excretion rate(UAER) and ambulatory plasma renin activity(aPRA) collected at mid-day were measured by radioimmunoassays. Subjectives were divided into 2 groups by aPRA value(2ng/ml/hr). RESULT: 14 cases were high renin group and 52 cases low renin group. The mean BP were 148.83/94.69mmHg in low renin group, and 146.57/98.07mmHg in high-renin group without difference. UAER were not different also between both groups. 23.07%(4/14) of non-dippers were included in high renin group and 25.58%(12/52) in low renin group without statistical difference. The aPRA was significantly related to UAER and systolic and diastolic mean blood pressure. Also UAER was related significantly to day mean blood pressures. CONCLUSION: Thus aPRA is thought to be a meaningful indicator to predict hypertensive renal target organ damage as well as blood pressure measured with 24-hr ABPM.
Blood Pressure*
;
Hypertension*
;
Plasma*
;
Radioimmunoassay
;
Renin*
10.A Clinical Review of Intussusception of Infancy and Childhood in Emergency Department.
Jae Gu KANG ; Sam Sik PARK ; Soon Joo WANG ; Jae Myung JUNG
Journal of the Korean Society of Emergency Medicine 1998;9(1):154-160
Intussusception is a condition of invagination of the proximal segment of bowel into the more distal receiving bowel. Intussusception is one of the common pediatric and surgical emergencies of infancy and childhood in Korea. Intussusception is the most common cause of acquired intestinal obstruction in infancy and childhood, and it needs emergency treatment. 1) On the age and sex distribution, the age under 15 month was the most common(70.6%), and the peak incidence was 3-12 months of age(60.1%). In sex distribution, male to female ratio was 1.25:1. 2) The seasonal distribution was summer(27.4%), spring, autumn and winter in order of frequency. 3) As to the etiology of Intussusception treated by surgery, idiopathic was the most common(75%). 4) The cardinal symptoms and signs were vomiting(72.5%), bloody or bloody mucoid stool(57.5%), abdominal pain(49.7%), abdominal distention(20.9%), abdominal mass(19.6%) and others in order of frequency. 5) On the hematologic finding, 60.8% revealed leukocytosis above 10,000/mm3. 6) As to the duration from the onset of the symptom to admission, 84.2% was within 24 hours, 9.8% was from 24 hours to 48 hours, and 5% was over 48 hours. 7) The common anatomical types were ileocolic(73.2%), and ileocecal(17.0%). 8) The success rate of air reduction was 84.3%. 9) In the method of operation, manual reduction was performed in 91.7% and intestinal resection in 8.3%. 10) The recurrence rate after air reduction was 12.4% and after operative manual reduction was 8.3%.
Emergencies*
;
Emergency Service, Hospital*
;
Emergency Treatment
;
Female
;
Humans
;
Incidence
;
Intestinal Obstruction
;
Intussusception*
;
Korea
;
Leukocytosis
;
Male
;
Recurrence
;
Seasons
;
Sex Distribution