1.A Case of Dysbaric Osteonecrosis in Commercial Diver.
Young Jun KWON ; Soo Jin LEE ; Jae Chul SONG
Korean Journal of Aerospace and Environmental Medicine 2000;10(4):357-360
Chronic complication of diving and working in compressed air is dysbaric osteonecrosis. Dysbaric osteonecrosis could be diagnosed by simple bone x-ray, in the case of exposure history to dysbaric atmosphere. The case is 44 years old man who worked as a shell fish diver for 20 years. He was exposed dysbaric atmosphere during diving. He had bone necrosis in both femur head, both distal femur and proximal tibia. He had multiple attacks of decompression sickness. Other causes of bone necrosis are ruled out. We conclude that diver's bone necrosis is dysbaric osteonecrosis.
Adult
;
Atmosphere
;
Compressed Air
;
Decompression Sickness
;
Diving
;
Femur
;
Femur Head
;
Humans
;
Necrosis
;
Osteonecrosis*
;
Tibia
3.The Effect of Disodium Etidronate on Phosphatase Activity in Experimental bone Formation of Rats
Kwon Jae ROH ; Young Soo AHN ; Joo Young CHOI
The Journal of the Korean Orthopaedic Association 1990;25(6):1761-1776
The bone formation of periarticular connective tissue after head injury and total hip arthroplasty is included in the category of heterotopic ossification. Induction of a new bone formation in the soft tissue is related to various materials such as bone morphogenic protein. The alkaline phosphatase and acid phosphatase act as important factors in the formation and absorption of the bone. The acid phospatase has the important function of acting as the control with specific activity of phosphatase in vivo. Cholecalciferol induces absorption of the calcium in the alimentary tract and bone resorption and increment of bone calcification, whereas disodium etidronate inhibits the deposition and dissolution of calcium salt and formation of heterotopic bone. This paper reports on the relationship of alkaline phosphatase and various phosphoaminoacid phosphatase which affect the cellular differentiation and remodelling in the heterotopic ossification, with the effect of cholecalciferol and disodium etidronate on the heterotopic bone induction in rats. The following results were obtained: 1. The contents of the calcium in the implanted bone matrix increased markedly from two to five weeks. There was no changes in the calcium content by cholecalciferol or in the administration of small doses of disodium etidronate (5mg/kg). However, in the administration of large dose of disodium etidronate (25mg/kg), calcium mobilization was totally suppressed for the whole period of the experiment. 2. The protein content in the implanted bone matrix did not much change for the whole period of the experiment and the administratinn of cholecalciferol or disodium etidronate also had no effect on the protein content. 3. The activities of alkaline phosphatase in the implanted bone matrix peaked at two weeks in control or cholecalciferol group, whereas disodium etidronate admninstration caused the highest activity in the third week. 4. The activity of acid phosphatase in the implanted bone matrix increased in first and third weeks by cholecalciferol treatment. Disoidum etidronate inhibited the activity of the acid phosphatase in the first, fourth & sixth weeks of implantation. 5. The activity of phosphoserine phosphatase increased due to cholecalciferol treatment, but was significantly inhibited by disodium etidronate (25mg/kg) treatment. 6. The activity of phosphothreonine phosphatase in the implanted bone matrix slightly increased due to cholecalciferol treatment, whereas the activity decreased significantly for the whole period of the experiment by disodium etidronate (25mg/kg) treatment. 7. The activity of phosphotyrosine phosphatase in the implanted bone matrix was not change much for the whole period of the experiment and the administration of cholecalciferol or disodium etidronate had no effect on the activity of phosphotyrosine phosphatase. In conclusion, the disodium etidronate (25mg/kg) almost completely inhibited the molilization of calcium and the activities of acid phosphatase, phosphoserine and phosphothreonine phosphatases. Therefore, it can be suggested that the above phosphatases are closely related to the action mechanism of disodium etidronate.
Absorption
;
Acid Phosphatase
;
Alkaline Phosphatase
;
Animals
;
Arthroplasty, Replacement, Hip
;
Bone Matrix
;
Bone Resorption
;
Calcium
;
Cholecalciferol
;
Connective Tissue
;
Craniocerebral Trauma
;
Etidronic Acid
;
Ossification, Heterotopic
;
Osteogenesis
;
Phosphoric Monoester Hydrolases
;
Phosphoserine
;
Phosphothreonine
;
Protein Tyrosine Phosphatases
;
Rats
4.A Clinical Observation of Acetabular Fractures
Chil Soo KWON ; Kwang Yoon SEO ; Jae Yul CHOI
The Journal of the Korean Orthopaedic Association 1978;13(3):369-375
Thirty nine cases (38 patient) of acetabular fracture and fracture-dislocation were treated in our hospital during the period 1973 to 1977. The short summary of the observation were as follows; 1. Among 39 cases (24 were male and 15 female), the most common cause of acetabular fracture and fracture-dislocation was traffic accident. 2. The acetabular fractures and fracture-dislocations were treated by conservative measures in 25 cases and by open reduction in 14 cases. The results were as follows; excellent in 12(30%), good in 19(48%), fair in 5 (15%) and poor in 3 cases (7%). 3. Among 3 cases of poor results, secondary traumatic arthritis and limitation of motion were observed in two cases and aseptic necrosis of the femoral head, in one case. 4. The result of conservative treatment was satisfactory if the stability of the hip joint and the congruity of the superior weight bearing dome of the acetabulum was well preserved.
Accidents, Traffic
;
Acetabulum
;
Arthritis
;
Head
;
Hip Joint
;
Humans
;
Male
;
Necrosis
;
Weight-Bearing
5.The Clinical Results of Tension Band Wiring
Chil Soo KWON ; Kwang Yoon SEO ; Seung Jae LEE
The Journal of the Korean Orthopaedic Association 1982;17(6):1203-1208
We have experienced 52 intra-articular fractures(24 malleolar, 17 patellar, 11 olecranon) treated with tension band wiring from 1972 to 1981 and the results are as followings; 1. The operative technique is relatively simple and easy. 2. In avulsion fractures without communition, anatomical reduction and rigid internal fixation can be achieved. 3. In comminuted fractures, the fragments can be securely fixed with a few additional K-wires including tension band wiring. 4. In avulsion fractures, where the fragment is either too small for screw fixation or too osteoporotic a tension band wiring can be applied with no difficulty. 5. Early joint motion reduces the functional disability and promote the fracture healing.
Fracture Healing
;
Fractures, Comminuted
;
Joints
;
Olecranon Process
6.Tuberculosis of the breast: report of 3 cases.
Jae Hong KWON ; Name Cheon CHO ; Kwang Soo YOON ; Byoung Seon RHOE ; Soo Yong KIM
Journal of the Korean Surgical Society 1992;42(6):856-861
No abstract available.
Breast*
;
Tuberculosis*
7.Outcome of low anterior resection by EEA stapler and standard manual anastomosis in rectal cancer.
Jae Hong KWON ; Nam Cheon CHO ; Kwang Soo YOON ; Dae Sung KIM ; Soo Yong KIM
Journal of the Korean Surgical Society 1991;41(3):352-357
No abstract available.
Rectal Neoplasms*
8.Malignant Granular Cell Tumor: Report of One Case
Byeong Yeon SEONG ; Chang Uk CHOI ; Hee KWON ; Jae Wook KWON ; Hee Soo CHOI ; Eui Han KIM
The Journal of the Korean Orthopaedic Association 1987;22(3):780-784
Granular cell tumor is one of the rare tumorous condition. At present there are estimated 600 reported examples of the tumor in the medical literature. Malignant granular cell tumor is a well established but extremely rare entity that is found in appr- oximately 2 % of all granular cell tumor. Diagnosis should be restricted to neoplasms that are similar in their histological appearance to benign granular cell tumors but can be seperated on the basis of cellular pleomorphism, mitotic activity, and, most importantly, their capacity to produce metastases. The authors had experienced that a 55 years old male patient had two large malignant granular cell tumors at the left thigh and left inguinal area with metastatic lesion.
Diagnosis
;
Granular Cell Tumor
;
Humans
;
Male
;
Neoplasm Metastasis
;
Thigh
9.Rhabdomyoma of Inferior Rectus Muscle Manifesting as Vertical Eye Movement Limitation
Ji Min KWON ; Jae Hwan KWON ; Soo Jung LEE
Korean Journal of Ophthalmology 2019;33(4):397-398
No abstract available.
Eye Movements
;
Rhabdomyoma
10.The Effects of Handgrip and Cold Pressor Test on Mitral Flow in Patients with Left Ventricular Hypertrophy.
Hark RIM ; Shin Ho LEE ; Soo Yeol AHN ; Jin Kyoo KIM ; In Kwon JUNG ; Jae Woo LEE
Korean Circulation Journal 1991;21(6):1182-1189
BACKGROUND: Handgrip and cold pressor test may increase the afterload of the heart. And in left ventricular hypertrophy, it is known that mitral flow pattern is affected by decreased left ventricular compliance. We investigated the effects of handgrip and cold pressor test on mitral flow pattern in patients with left ventricular hypertrophy. METHODS: Handgrip and cold pressor test were performed in 12 subjects with left ventricular hypertrophy and in 14 healthy normal subjects. In supine position, blood pressure, heart rate and Doppler echocardiographic parameters(early peak flow velocity : E, atrial peak flow velocity : A) were obtained at rest, 1 and 3 minutes after the onset of tests respectively. RESULTS: In both groups, handgrip and cold pressor test increased blood pressure slightly without a statistical significance. In left ventricular hypertrophy group, there were significant increments in heart rates at 1 minute of handgrip (78+/-12min-1, p<0.001) and cold pressor test(77+/-7min-1, p<0.05) as compared to that at rest (73+/-12min-1). Mitral flow velocities did not show significant change after the tests in control group. A waves after 1 minute of handgrip(85.2+/-18.4cm/sec, p<0.05) and cold pressor test (87.3+/-17.8cm/sec, p<0.001) showed significant increases as compared to that at rest (79.1+/-14.9cm/sec) in left ventricular hypertrophy group whereas E waves did not. CONCLUSION: Although handgrip and cold pressor tests did not affect the mitral flow significantly in control group, each test raised A waves in left ventricular hypertrophy group. These results suggest that increased A waves may be due to a rise in afterload and decreased left ventricular compliance caused by handgrip and cold pressor test in left ventricular hypertrophy group.
Blood Pressure
;
Compliance
;
Echocardiography
;
Heart
;
Heart Rate
;
Humans
;
Hypertrophy, Left Ventricular*
;
Supine Position