1.The effects of hyperbaric oxygen therapy on the survival of dorsal random skin flap: an experimental study in streptozotocin-induced diabetic rats.
Heung Sik PARK ; Yoon Jae CHUNG ; Hong Kyu CHO
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(6):966-977
There have been increasing interests of diabetes in the realm of plastic surgery due to problems like foot ulcer as a complication, delayed wound healing or higher failure rates of flap surgery. Main pathology in diabetes is microvascular compromise as well as metabolic derangements. The disturbance in microvascular circulation results in ischemic environments in the body and acts as a main factor that determines the limit of reconstructive or aesthetic plastic surgery. A useful method to overcome such problems is the use of hyperbaric oxygen therapy, which is known to be effective in the treatment of ischemic skin ulcer or osteoradionecrosis. However, there have been few studies on the survival of diabetic random skin flap or the effects of hyperbaric oxygenation directed to increase survival of such flap. In our study, we supposed that the survival of diabetic random skin flap was diminished owing to compromised microvascular pathology and blood rheology, and metabolic derangements, so we hypothesized that hyperbaric oxygen therapy has both reversible and irreversible effects on the survival of ischemic random skin flap in Streptozotocin-induced diabetic rats. Increase of local transcutaneous oxygen concentration, O2 affinity in blood and dysmorphogenesis of red blood cells are reversible and relatively short-term effects and promotion of neoangiogenesis is irreversible or long-term effects. We intended to confirm that hyperbaric rats and to compare the effects between preoperative and postoperative hyperbaric oxygenation on the survival of such flap. And we expect the additional effects of hyperbaric oxygenation on metabolism in diabetic rat, such as lowering the blood glucose level and solving the arrested weight gain. We divided Streptozotocin-induced diabetic rats into three groups: the first was non-treatment diabetic group, the second was preoperative hyperbaric oxygen treated diabetic group(100% O2, 2 atm, 90min, 15sessions, twice a day), and the third was postoperative hyperbaric oxygen treated group(100% O2, 2atm, 90min, 15sessions, twice a day). After elevation of random skin flap on dorsum of diabetic rats, we evaluated the extent of flap survival by measuring the necrotic areas at 3rd, 7th, 10th, and 13th postoperative days. At that time, we intended to evaluate both effects on flap survival by preoperative and postoperative hyperbaric oxygen therapy. As a result, flap survival of non-treated diabetic group was 41% at 13th postoperative days. In diabetic groups with preoperative and postoperative hyperbaric oxygen therapy, flap survival were increased to 64.6% and 62.4% respectively. Diabetic groups with hyperbaric oxygen therapy have a tendency of meaningful decrement in blood glucose level. However, there were no meaningful differences between preoperative and postoperative hyperbaric oxygen therapy. Hyperbaric oxygen therapy has no effective correlations with body weight changes. We conclude that hyperbaric oxygen therapy has some useful effects on the survival of diabetic random skin flap.
Animals
;
Blood Glucose
;
Body Weight Changes
;
Erythrocytes
;
Foot Ulcer
;
Hyperbaric Oxygenation*
;
Metabolism
;
Osteoradionecrosis
;
Oxygen
;
Pathology
;
Rats*
;
Rheology
;
Skin Ulcer
;
Skin*
;
Surgery, Plastic
;
Weight Gain
;
Wound Healing
2.The Morphometric Study on Soleal Line of the Tibia in Korean.
Sung Sik PARK ; Keun Young BAE ; Hyung Tae KIM ; Jae Rhyong YOON ; Jae Kwon CHOI
Korean Journal of Physical Anthropology 1990;3(2):99-103
The soleal line in 115 (left; 61, right; 54) cases of tibiae was studied morphometrically by the method of Mysorekar and Nandedkar. 1. The soleal line showed a uniform character throughout in 26 cases and a mixed characters in 89 cases. The bones showing uniform character were seen generally as a lineal line or wide line. 2. The soleal line having mixed characters divided into three parts. In the upper and middle thirds, the major type of line was wide line. In the lower third, the line was commonly seen as a lineal line. In about 12% of the bones examined the line was seen as a groove, particularly in the middle and lower thirds. 3. The soleal line commenced 1-2cm below the fibular facet In about 61% of cases. 4. The length of the soleal line was 10.5cm, and the ratio to that of the tibia was about 30%. The results of this study provide the characters of the soleal tne of the tibia in Korean. The soleal line, unlike the textbook description, generally shows mixed characters of a line.
Methods
;
Tibia*
3.Clinical analysis of tourniquet paralysis.
Jae Yong JEON ; Jung Yoon LEE ; Hee Chang AHN ; Yae Sik HAN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(1):141-146
No abstract available.
Paralysis*
;
Tourniquets*
4.Small Round Structured Virus (SRSV) Outbreak Among Elementary School Students in Wonju Province.
Unyeong GO ; Young Hak SHIN ; Jung Sik YOO ; Youngmee JEE ; Ki Soon KIM ; Jae Deuk YOON
Korean Journal of Infectious Diseases 2001;33(3):210-213
No abstract available.
Gangwon-do*
;
Humans
5.Oxygen Consumption at Different Treadmill Speed and Grade in Athletes and Nonathletes.
Jeong Heui CHOE ; Hyeong Jin KIM ; Eun Kyoung YANG ; Yoon Yub PARK ; Jae Sik PARK
Korean Circulation Journal 1995;25(6):1175-1182
This study was aimed to elucidate the relationship between combinations of treadmill speed-grade and oxygen consumption(Vo2). Twenty athetic and 20 non-athletic male college students aged 19-24yr were employed to exercise on a treadmill using 4 speeds(4.02, 5.47, 6.76 and 8.05km/h) and 5 grades(0, 8, 12, 16 and 20%). A fixed speed was selected for each session with the grade increased every 3 min. The Vo2, heart rate, stride frequency and stride length were measured during the last min of each 3-min stage. Vo2increased linearly with increasing speed and grade showing significant multiple correlations in nonathletes(Vo2=3.64x+0.831y+0.031xy-7.03, R=0.98, P<0.01) and athletes(Vo2=3.48x+0.324y+0.112xy-5.74, R=0.99, P<0.01). Stride frequency and length tended to increase with increasing speed except for the transition from walking to runnig at 8.05Km/h at which the stride frequency ran up much higher with the stride length getting lower than at 6.76Km/h. Heart rate increased linearly with increasing Vo2. The rate of increase was higher during walking than during running. These results indicate that athletes have higher rate of increase in Vo2than nonathletes at near-maximal exercise and may be used as a guideline in predicting maximum oxygen comsumption and in prescribing exercise intensity.
Athletes*
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Heart Rate
;
Humans
;
Male
;
Oxygen Consumption*
;
Oxygen*
;
Running
;
Walking
6.Epididymal Anomalies in Cryptorchidism and Hydrocele : Association with Patent Processus Vaginalis.
Korean Journal of Urology 1999;40(9):1231-1234
PURPOSE: Epididymal anomalies in boys with an undescended testis have been well documented and most undescended testes are associated with patent processus vaginalis. However, the incidence of epididymal anomalies in descended testes has not well known. We performed a prospective study to determine the relationship between epididymal anomalies and patency of processus vaginalis in boys with hydrocele or cryptorchidism. MATERIALS AND METHODS: From January 1997 to February 1988, epididymal morphologies and the degrees of patency of processus vaginalis(closed, partially closed and open) were examined in 35 boys with hydrocele(37 testes) and 28 boys with cryptorchidism(29 testes) at the surgeries. RESULTS: No epididymal anomaly was found in all 3 hydroceles with closed processus vaginalis. Epididymal anomalies were found in 13 of 22 hydroceles with partially closed processus vaginalis and in 9 of 12 hydroceles with open processus vaginalis. All boys with undescended testes had open processus vagnialis and the epididymal anomalies were found in 27 of 29 undescended testes. The incidence of epididymal anomalies was highest in cryptorchid testes with open processus vaginalis and lowest in descended testes with closed processus vaginalis. Furthermore, epididymal anomalies were found to be more severe in association with more cranially located testes. CONCLUSIONS: The higher incidence of epididymal anomalies were associated with ipsilateral patency of processus vaginalis and testicular position. This finding suggests that the role of the epididymis in testicular descent may not be essential.
Cryptorchidism*
;
Epididymis
;
Incidence
;
Male
;
Prospective Studies
;
Testis
7.Ultrasonographic findings of accessory breast.
Ki Keun OH ; Jae Hyun CHO ; Choon Sik YOON ; Mi Hye KIM
Journal of the Korean Radiological Society 1993;29(4):839-843
Accessory breast is an ectopic breast tissue from developemental remnants. It sometimes begins to make symptoms, pain and swelling, during premenstrual period or pregnancy. For it has been known as a rere condition, it has occasionally misdiagnosed as a abnormal mass, such as lymphadenitis or hidradenitis. We have analyzed 52 accessory breast tissues prospectively, to document the characteristic findings of accessory breast. In summary, the characteristic sonographic findings of accessory breast were the presence of breast tissue superficial to the axillary fascia or underlying fascia if not in axilla, resembling the patient's own breast pattern, the presence of converging appearance of dilated ducts, presence of nipple and/or areola, the obliteration of inner wall of dermis, the obliteration of sucutaneous fat layer, and the downward displacement of axillary fascia or underlying fascia if not in axilla wighout interruption.
Axilla
;
Breast*
;
Dermis
;
Fascia
;
Hidradenitis
;
Lymphadenitis
;
Nipples
;
Pregnancy
;
Prospective Studies
;
Ultrasonography
8.Preoperative abdominal computed tomography in gastric malignant.
Jae Sik JOO ; Jang Young KANG ; Seung Taek LEE ; Sung Kyoo LEE ; Yoon Jung YOO
Journal of the Korean Cancer Association 1993;25(5):617-624
No abstract available.
9.A Case of Squamous Cell Carcinoma and Bowen's Disease Associated with Superficial Disseminated Porokeratosis.
Hong Yoon YANG ; Tchae Sik NAM ; Young Tae KIM ; Jae Hong KIM
Annals of Dermatology 1990;2(1):31-34
We describe the clinical and pathologic observation of a 50-year-old man with superficial disseminated porokeratosis who developed a squamous cell carcinoma on the dorsum of his right thumb and Bowens disease on his right upper arm. The tumors were surrounded by lesions of superficial disseminated porokeratosis and were thought to develop from the dysplastic epidermal cells located under the comoid lamellae.
Arm
;
Bowen's Disease*
;
Carcinoma, Squamous Cell*
;
Epithelial Cells*
;
Humans
;
Middle Aged
;
Porokeratosis*
;
Thumb
10.Simultaneous Bilateral Cementless Total Hip Arthroplasty: a Minimum 17-year Follow-up Study - Comparison Study with Unilateral Cementless Total Hip Arthroplasty -.
Sung Kwan HWANG ; Jang Hee PARK ; Won Sik YOON ; Jae Hack CHA
Hip & Pelvis 2013;25(1):21-29
PURPOSE: Long-term follow-up results of concurrent bilateral or unilateral cementless hip arthroplasty were compared. MATERIALS AND METHODS: Forty eight and 49 patients with concurrent bilateral and unilateral hip artrhoplasties who had more than a 17-year follow-up time were selected. At final follow-up, mean ages were 69.1 and 66.7 years old in the bilateral and unilateral groups, respectively. Mean follow-up times were 21.5 and 22.4 years in the bilateral and unilateral groups, respectively. Clinical results were attained using Harris hip score and standardized anteroposterior and lateral view X-rays. RESULTS: The bilateral group had mean Harris scores of 44.3(standard deviation 3.78) preoperatively, and 81.2 (10.75) at final follow-up. For the unilateral group, the mean scores were 46.5(3.27) preoperatively, and 80.1 (12.05) at final follow-up. At final follow-up, an acetabular cup was securely located in 78.9% and 82.8% of the bilateral and unilateral groups, respectively, and all cases showed firm fixation of the femoral stem in both groups. Osteolysis around the cup and stem were found in 26.3% and 31.4% of the bilateral group and 16.6% and 17.1% of the unilateral group, respectively. Polyethylene wear rate was 0.17 mm/yr and 0.16 mm/yr in the unilateral and bilateral groups, respectively. Using the Kaplan-Meier method, 17-year survival rates for cup and stem were 78% and 89% in the bilateral group, respectively, and 78% and 86% in the unilateral group, respectively. CONCLUSION: In 17-year long-term follow-up, concurrent bilateral hip arthroplasty was insignificantly different clinically and radiologically from the result of unilateral hip arthroplasty.
Arthroplasty
;
Follow-Up Studies
;
Hip
;
Humans
;
Osteolysis
;
Polyethylene
;
Survival Rate