PURPOSE: To evaluate the safety and clinical effects of extracorporeal magnetic innervation (ExMI) for urinary incontinence after radical prostatectomy. MATERIALS AND METHODS: Thirty-two patients with urinary incontinence after radical prostatectomy were randomly assigned to receive either ExMI treatment or pelvic floor training alone. For the ExMI group, treatment was initiated 1 week after catheter removal and the treatment sessions were for 20 minutes, twice a week, for 8 weeks. For the control group, only pelvic floor muscle exercises were performed. Patients were followed up at 1 week and 1, 2, 3, and 6 months. Outcomes were assessed by 24-hour pad weight testing, the number of pads used daily, and a quality-of-life survey (I-QoL). RESULTS: Leakage weight during the 24 hours after removing the catheter was 655g and 646g for the ExMI and control groups, respectively. At 1 month, it was 147g and 187g; at 2 months, 33g and 81g (p=0.001); and at 3 months, 9g and 45g (p=0.001), respectively. Finally, 6 months later, leakage weight was less than 10g in both groups. The number of pads used daily after removing the catheter was 4.2 and 4.1 for the ExMI and control groups, respectively. At 1 month, it was 1.5 and 1.8; at 2 months, 0.6 and 0.9 (p=0.033); and at 3 months, 0.1 and 0.6 (p=0.002), respectively. Finally, 6 month later, pads counts were 0 and 0.1. I-QoL scores decreased after surgery, but gradually improved in both groups. No other side effects or adverse events were observed. CONCLUSIONS: ExMI provided earlier recovery of continence than in the control group after radical prostatectomy.
Catheters ; Exercise ; Humans ; Magnetics ; Magnets ; Muscles ; Pelvic Floor ; Prostatectomy ; Urinary Incontinence

BACKGROUND: Exposure to hyperoxia causes extensive injury to lung tissue, which resembles the pathologic changes of the adult respiratory distress syndrome. To observe the relationship between the pulmonary oxygen toxicity and duration of exposure to oxygen, 100% oxygen was exposed to Wistar rats. METHODS: 35 rats were partitioned into 5 groups (n=7 in each group). Gr. I breathed room air. Gr. II, III, IV and V were exposed to 99~100% oxygen for 24 hrs, 48 hrs, 60 hrs and 72 hrs. Wet lung/body weight (WW/BW), dry lung/body weight (DW/BW), wet/dry lung weight (WW/DW) and I-albumin flux ratio were measured in each group. RESULTS: After exposure for 72 hrs in Gr. V, 3 rats were dead. WW/BW in Gr. I was 0.69+/-0.04 and increased to 1.10+/-0.28 in Gr.II (P<0.05), which was maintaind until 60 hrs. It showed marked increase in Gr. V; 2.16+/-0.60. DW/BW, WW/DW and I-albumin flux ratio increased after 48 hrs of hyperoxia. WW/BW and DW/BW in Gr. V and I-flux ratio in Gr. IV showed significant increase compared with Gr. I, II and III. CONCLUSIONS: The results suggest that pulmonary capillary permeability begins to change after 24 hrs of hyperoxia and that definite permeability change to albumin and fluid accumulation in the lung are demonstrable from 48 hrs-exposure to 99~100% oxygen and aggravated by duration of oxygen exposure.
Animals ; Capillaries* ; Capillary Permeability* ; Hyperoxia ; Lung ; Oxygen* ; Permeability ; Rats* ; Rats, Wistar ; Respiratory Distress Syndrome, Adult

In 1971, for purpose of reduction of peak stress occuring in cement and trabecular bone of the acetabulum, Harris reported a series of metal-backed acetabular components with removable polyethylene liners that could be replaced if excessive wear occured. Modular designs of hip prostheses have become popular recently, but they introduce the risk of disassembly of the components postoperatively. And introduce of loosening and infection of femoral or acetabular components by debris of polyethylene liner. We report a case of mechanical disassembly of polyethylene liner in cementless metal backed cup, and review previously reported articles.
Acetabulum ; Hip Prosthesis ; Polyethylene

Inguinoscrotal bladder hernia is relatively common in obese males over 50 years old, especially patients with benign prostate hyperplasia. Various imaging modalities are used for diagnosis of inguinoscrotal bladder hernia. In particular, ultrasonography has many benefits, including non-invasiveness, and the fact that it does not require exposure to radiation; however, no domestic cases of ultrasonographic diagnosis of inguinoscrotal bladder hernia have been reported. The authors report on a case of a 67-year-old male patient with right scrotal swelling diagnosed as inguinoscrotal bladder hernia by ultrasonography, including three-dimensional imaging. Findings on ultrasonography showed a sacular lesion in the scrotum, which was connected to the urinary bladder through the inguinal canal; additional findings on CT, PET, and cystography showed that the entire lesion had a dumbbell shape.
Hernia ; Hernia, Inguinal ; Humans ; Hyperplasia ; Imaging, Three-Dimensional ; Male ; Prostate ; Scrotum ; Urinary Bladder

PURPOSE: To analyze the stress distribution of the implant and its supporting structures through 3D finite elements analysis for implants with different hexagon heights and to make the assessment of the mechanical stability and the effect of the elements. MATERIALS AND METHODS: Infinite elements modeling with CAD data was designed. The modeling was done as follows; an external connection type Phi 4.0 mm x11.5 mm Osste(R) USII (Osstem Co., Pusan, Korea) implant system was used, the implant was planted in the mandibular first molar region with appropriate prosthetic restoration, the hexagon (implant fixture's external connection) height of 0.0, 0.7, 1.2, and 1.5 mm were applied. ABAQUS 6.4 (ABAQUS, Inc., Providence, USA) was used to calculate the stress value. The force distribution via color distribution on each experimental group's implant fixture and titanium screw was studied based on the equivalent stress (von Mises stress). The maximum stress level of each element (crown, implant screw, implant fixture, cortical bone and cancellous bone) was compared. RESULTS: The hexagonal height of the implant with external connection had an influence on the stress distribution of the fixture, screw and upper prosthesis and the surrounding supporting bone. As the hexagon height increased, the stress was well distributed and there was a decrease in the maximum stress value. If the height of the hexagon reached over 1.2 mm, there was no significant influence on the stress distribution. CONCLUSION: For implants with external connections, a hexagon is vital for stress distribution. As the height of the hexagon increased, the more effective stress distribution was observed.
Dental Implants ; Molar ; Plants ; Prostheses and Implants ; Titanium

A gastric intramural hematoma is very rare and commonly associated with trauma, anticoagulation therapy, coagulopathy, pancreatic disease, aneurysm and peptic ulcer disease. This is a case of gastric intramural hematoma which occurred in a patient taking aspirin after hypertonic saline-epinephrine injection for bleeding from a biopsy site. We describe a case of gastric intramural hematoma that was successfully managed with conservative therapy.
Aneurysm ; Aspirin ; Biopsy ; Epinephrine ; Hematoma* ; Hemorrhage ; Hemostasis* ; Humans ; Pancreatic Diseases ; Peptic Ulcer ; Saline Solution, Hypertonic

PURPOSE: In accordance with the increasing number of accidents caused by various reasons and recently developed fine diagnostic skills, the incidence of orbital blow-out fracture cases is increasing. As it causes complications, such as diplopia and enophthalmos, surgical reduction is commonly required. This article reports a retrospective series of 5 blow-out fracture cases that had unusual nerve injuries after reduction operations. We represents the clinical experiences about treatment process and follow-up. METHODS: From January 2000 to August 2009, we treated total 705 blow-out fracture patients. Among them, there were 5 patients(0.71%) who suffered from postoperative neurologic complications. In all patients, the surgery was performed with open reduction with insertion of Medpor(R). Clinical symptoms and signs were a little different from each other. RESULTS: In case 1, the diagnosis was oculomotor nerve palsy. The diagnosis of the case 2 was superior orbital fissure syndrome, case 3 was abducens nerve palsy, and case 4 was idiopathic supraorbital nerve injury. The last case 5 was diagnosed as optic neuropathy. Most of the causes were extended fracture, especially accompanied with medial and inferomedial orbital blow-out fracture. Extensive dissection and eyeball swelling, and over-retraction by assistants were also one of the causes. Immediately, we performed reexploration procedure to remove hematomas, decompress and check the incarceration. After that, we checked VEP(visual evoked potential), visual field test, electromyogram. With ophthalmologic test and follow-up CT, we can rule out the orbital apex syndrome. We gave Salon(R)(methylprednisolone, Hanlim pharmaceuticals) 500 mg twice a day for 3 days and let them bed rest. After that, we were tapering the high dose steroid with Methylon(R)(methylprednisolon 4 mg, Kunwha pharmaceuticals) 20 mg three times a day. Usually, it takes 1.2 months to recover from the nerve injury. CONCLUSION: According to the extent of nerve injury after the surgery of orbital blow-out fracture, the clinical symptoms were different. The most important point is to decide quickly whether the optic nerve injury occurred or not. Therefore, it is necess is to diagnose the nerve injury immediately, perform reexploration for decompression and use corticosteroid adequately. In other words, the early diagnosis and treatment is most important.
Abducens Nerve Diseases ; Bed Rest ; Decompression ; Diplopia ; Early Diagnosis ; Enophthalmos ; Follow-Up Studies ; Hematoma ; Humans ; Incidence ; Linear Energy Transfer ; Oculomotor Nerve Diseases ; Optic Nerve Diseases ; Optic Nerve Injuries ; Orbit ; Orbital Fractures ; Retrospective Studies ; Visual Field Tests

No abstract available.

No abstract available.
Forehead ; Leiomyoma

OBJECTIVE: The aim of this study was to analize the biologic and molecular genetic characteristics of Lactobacillus spp. isolated from vagina of Korean healthy women and to perform a pilot clinical study on the treatment of vaginitis using the best Lactobacillus strain KLB 46. METHODS: Vaginal specimens were obtained from 205 Korean women with healthy vaginal ecosystems. 155 lactobacillus strains were used for catalase test, cell surface hydrophobicity (CSH) test and antimicrobial activity test. Also we identified the species prevalence by PCR-RFLP analysis of 16S rDNA gene and performed the minimal inhibitory concentrationtest using14 antibiotics to determine their patterns of antibiotic susceptibility. A pilot clinical trial of 8 bacterial vaginosis, 1 trichomonas vaginitis and 6 atrophic vaginitis using Lactobacillus crispatus KLB 46 was done by vaginal instillation (10(10)-10(11) cells/mL). RESULTS: 155 lactobacilli strains were isolated and all isolates showed high CSH and 61% of the isolates had higher CSH. L. acidophilus and L. crispatus were the most prevalent species by PCR-RFLP analysis of their 16S rDNA gene. And PCR-RFLP analysis suggested that KLB 46 was L. crispatus. The clinical study showed that the vaginal epithelial adherence rate was high as 77% for bacterial vaginosis and 33.3% for atrophic vaginitis. CONCLUSION: The predominating lactobacilli were L. crispatus and L. acidophilus in Korean women's vaginas. Although further study would be needed, L. crispatus KLB 46 is a good candidate of suitable probiotics for bacterial vaginosis.
Administration, Intravaginal ; Anti-Bacterial Agents ; Atrophic Vaginitis ; Catalase ; DNA, Ribosomal ; Ecosystem ; Female ; Humans ; Hydrophobic and Hydrophilic Interactions ; Lactobacillus* ; Molecular Biology* ; Prevalence ; Probiotics ; Trichomonas Vaginitis ; Vagina* ; Vaginitis* ; Vaginosis, Bacterial