1.A Case of Chinese Herbs Nephropathy.
Ki Deuk NAM ; Tae Won LEE ; Jung Heun NOH ; Mun Ho YANG ; Byung Su JO ; Seong Pyo HONG ; Chun Gyoo IHM ; Myung Jae KIM
Korean Journal of Nephrology 2000;19(4):751-755
No abstract available.
Asian Continental Ancestry Group*
;
Humans
2.The Effects of High-dose Vitamin C Administration on the Cell-mediated Immune Response in Mice.
Kahwa NOH ; Heun gon KIM ; Young ah SHIN ; Hyunja LIM ; Sung kyu MUN ; Yongtaek LEE ; Wang Jae LEE ; Dongsup LEE ; Young il HWANG
Immune Network 2003;3(3):211-218
BACKGROUND: Vitamin C is an essential nutrient, taken as a daily supplement by many people. Recently, high-dose vitamin C is considered as a therapeutic regimen in some clinical situations. Until now, few studies have been done with the effects of high-dose vitamin C on the immune response. METHODS: In this experiment, the effects of high-dose vitamin C on cell-mediated immune response in immunologically competent mice were evaluated. After intraperitoneal injection of 2.5, 5, or 10 mg/day of vitamin C for 10 days, delayed type hypersensitivity (DTH) was provoked against DNFB in the pinnae as a model for cell-mediated immune response. Severity of DTH reaction was evaluated as the thickness of pinnae, and the vitamin C levels were measured in the serum, liver, kidney, lung, pinnae, and splenocytes. RESULTS: After challenge, the thickness increased at its peak on the 2(nd) day in all groups. On the first day, the pinnae were thicker in the injected groups than in the control. On the contrary, the increment of the pinnae thickness was attenuated and the number of cells infiltrated in the site of DTH decreased proportionately to the amount of vitamin C administered from the second day on. With vitamin C exogenously given, the serum level peaked at 30 min after injection, and returned abruptly to its basal level without accumulation. However, it accumulated in the liver, kidney, and especially in the pinnae inflamed and splenopcytes, proportionately to the amount administered. CONCLUSION: Based on these results, it is suggested that, in one hand, exogenously administered high-dose vitamin C accumulated in the splenocytes and presumably changed the function of them resulting in the augmented cell-mediated immune response, as was revealed in the first day of DTH reaction. On the other hand, it seems likely that the vitamin C also showed anti-inflammatory effects.
Animals
;
Ascorbic Acid*
;
Dinitrofluorobenzene
;
Hand
;
Hypersensitivity
;
Injections, Intraperitoneal
;
Kidney
;
Liver
;
Lung
;
Mice*
;
Vitamins*
3.Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients.
Junghee RYU ; Ah Young OH ; Ji Seok BAEK ; Jin Hee KIM ; Sang Heon PARK ; Jae Mun NOH
Korean Journal of Anesthesiology 2014;66(4):278-282
BACKGROUND: This study determined the dose of remifentanil to use during insertion of a Classic(TM) laryngeal mask airway (LMA, The Laryngeal Mask Co., Nicosia, Cyprus) in elderly patients during emergency airway management when combined with a single dose of propofol. METHODS: Patients aged 65-80 years were enrolled. Anesthesia was induced with propofol 1 mg/kg, and then a blinded dose of remifentanil was infused over 30 s after confirming the patient's loss of consciousness. The dose of remifentanil was determined using Dixon's up-and-down method, starting at 0.5 microg/kg (a step size of 0.1 microg/kg). Insertion of the LMA was attempted 60 s after loss of consciousness. RESULTS: In total, 23 patients were recruited and the mean age +/- standard deviation was 72 +/- 3 years. The effective dose for successful LMA insertion in 50% of the patients (ED50) was 0.20 +/- 0.05 microg/kg. No patient needed more than 0.3 microg/kg. CONCLUSIONS: Remifentanil 0.20 +/- 0.05 microg/kg with propofol 1 mg/kg resulted in excellent LMA insertion in 50% of elderly patients without significant hemodynamic changes during emergency airway management.
Aged*
;
Airway Management*
;
Anesthesia
;
Emergencies*
;
Hemodynamics
;
Humans
;
Laryngeal Masks*
;
Propofol*
;
Unconsciousness
4.Complex regional pain syndrome in the young male population: a retrospective study of 200 Korean young male patients
Ho Jin LEE ; Chang Soon LEE ; Yongjae YOO ; Jae Mun NOH ; Je Hyuk YU ; Yong Chul KIM ; Jee Youn MOON
The Korean Journal of Pain 2019;32(4):292-300
BACKGROUND: The aim of this study was to investigate the clinical characteristics of complex regional pain syndrome (CRPS) in young male patients in South Korea, especially focusing on the association with military service. METHODS: From January 2007 to May 2017, we investigated the electronic medical records of 430 consecutive patients, aged 18 to 30 years, who visited Seoul National University Hospital Pain Center, with a suspected diagnosis of CRPS at the initial visit. The following patient details were available for analysis: demographic and disease-related variables, relevance to military service, medications, and the treatment modalities received. RESULTS: Out of 430 patients, 245 (57.0%) were diagnosed with CRPS, of which, 200 were male patients and 45 were female patients. Of the male patients, 95 (47.5%) developed CRPS during military service. CRPS during military service was more likely to result from sprain/strain, and the incidence of CRPS was significantly higher in the lower extremities in patients from the military service group than in those from the non-military service group. During the follow-up period, 37.9% of male CRPS patients (n = 61/161) were treated successfully. Patients with moderate to severe initial pain intensity, and diagnosed during their military service, showed better outcomes. CONCLUSIONS: Our results demonstrated that manifestation of CRPS in the young Korean population was more common in male and among those male CRPS patients, about half the cases developed during the military service period.
Chronic Pain
;
Diagnosis
;
Electronic Health Records
;
Epidemiology
;
Female
;
Follow-Up Studies
;
Humans
;
Incidence
;
Korea
;
Lower Extremity
;
Male
;
Military Medicine
;
Military Personnel
;
Neuralgia
;
Pain Clinics
;
Retrospective Studies
;
Seoul
;
Stress, Psychological