1.Clinical Studies of Measles in Infancy.
Journal of the Korean Pediatric Society 1995;38(7):907-913
No abstract available.
Measles*
2.A Clinical Observation on 55 Cases of Neonatal Sepsis.
Yeungnam University Journal of Medicine 1988;5(2):161-169
Neonatal Sepsis is a frequent and important cause of morbidity and mortality in the neonatal period. This study was undertaken to observe the 55 cases of proven neonatal sepsis among 6,717 newborn infants under 4 weeks of age, admitted to the nursery of Yeungnam University Hospital from May 1, 1983 to April 30, 1988. We observed following results: 1. The morbidity rate of male (1.12%) was higher than that of female (0.44%) significantly (p<0.05). 2. The morbidity rate of prematurity (2.65%) was higher than that of full term (0.76%) significantly (p<0.05). 3. The incidence of perinatal obstetric complications in early onset neonatal sepsis was higher than that of late onset neonatal sepsis (38.5% vs 10.3%, p<0.05). 4. The common clinical manifestations were poor feeding (52.7%), jaundice (45.5%), diarrhea (30.9%) and irritability (30.9%). 5. Among the causative organism, gram positive organisms were predominated and Staphylococcus epidermidis was the most common organism. There was no difference in the causative organisms between early onset and late onset sepsis.
Diarrhea
;
Female
;
Humans
;
Incidence
;
Infant, Newborn
;
Jaundice
;
Male
;
Mortality
;
Nurseries
;
Sepsis*
;
Staphylococcus epidermidis
3.Treatment of PDA in premature newborns with mefenamic acid.
Jae Joon LEE ; Young Hwan LEE ; Son Moon SHIN
Yeungnam University Journal of Medicine 1993;10(2):506-511
This study was conducted to examine the effect of mefenamic acid for treatment of PDA in premature newborns. Ductus arteriosus is reopened by locally produced prostaglandin E2 in a premature newborn during hypoxia. Mefenamic acid is one of non-steroidal antiinflammatory drugs acting by inhibition of cyclo-oxygenase in the prostaglandin synthesis pathway. For three premature newborns with PDA, we administered mefenamic acid and evaluated them with echocardiography to study the effect of mefenmic acid for closure of PDA. In all three babies, ductus arteriosus was closed successfully. We feel that mefenamic acid is safe and effective medication for treatment of PDA in premature newborns, but further-study need to be conducted with larger numbers of cases to confirm this effect.
Anoxia
;
Dinoprostone
;
Ductus Arteriosus
;
Echocardiography
;
Humans
;
Infant, Newborn*
;
Mefenamic Acid*
;
Prostaglandin-Endoperoxide Synthases
4.A Clinical Study on Low Birth Weight Infants.
Han Ku MOON ; Jung Ok KIM ; Jae Honng PARK ; Son Moon SHIN ; Jeong Ok HAH
Yeungnam University Journal of Medicine 1987;4(2):97-103
Neonatal and obstetrical problems related to the low birth weight infants were evaluated by a retrospective review of the medical records of the 186 low birth weight infants born at Yeungnam University Hospital during 3 years and 8 months from May 1, 1983 to February 28, 1987. The results were as follows: 1. The incidence of the low birth weight infants was 4.98% among 3,803 live births. 2. Male to female ratio was 1.02:1. 3. The incidence of the low birth weight infants was lowest in mothers of 25 to 29 years, increased in mothers of 19 years of less and 30 to 39 years significantly. 4. There was no difference in the incidence of low birth weight infants between primiparous and multiparous mothers. 5. Common obstetrical complications associated with low weight infants were multiple pregnancy, toxemia and premature rupture of membrane in order of frequency. 6. Common neonatal problems in low birth weight infants were jaundice, idiopathic respiratory, distress syndrome, asphyxia and metabolic derangement such as hypocalcemia and hypoglycemia in order of frequency.
Asphyxia
;
Clinical Study*
;
Female
;
Humans
;
Hypocalcemia
;
Hypoglycemia
;
Incidence
;
Infant*
;
Infant, Low Birth Weight*
;
Infant, Newborn
;
Jaundice
;
Live Birth
;
Male
;
Medical Records
;
Membranes
;
Mothers
;
Pregnancy
;
Pregnancy, Multiple
;
Retrospective Studies
;
Rupture
;
Toxemia
5.A clinical effect of retreatment by prothionamide, cycloserine, para-aminosalicylic acid, streptomycin(kanamycin or tuberactinomyc-in) on pulmonary tuberculosis.
Cheol Shick SHIN ; Young Jae IM ; Young Jun KIM ; Seok Shin KOH ; Moon Shik KIM
Tuberculosis and Respiratory Diseases 1992;39(2):167-171
No abstract available.
Aminosalicylic Acid*
;
Cycloserine*
;
Prothionamide*
;
Retreatment*
;
Tuberculosis, Pulmonary*
6.Comparision of the Two Groups between Autologous Bone Chips and Cage as Posterior Lumbar Interbody Fusion in Spondylolisthesis Patients.
Pill Jae SHIN ; Chang Hyun KIM ; Jae Gon MOON ; Ho Kook LEE ; Do Yun HWANG
Journal of Korean Neurosurgical Society 2000;29(4):507-513
No abstract available.
Humans
;
Spondylolisthesis*
7.Left to right ratio of autopneumonectomy state in pulmonary tubercu-losis patients.
Cheol Shick SHIN ; Jae Man JEONG ; Young Jae IM ; Young Jun KIM ; Seok Shin KOH ; Moon Shik KIM
Tuberculosis and Respiratory Diseases 1992;39(4):343-347
No abstract available.
Humans
8.The treatment of recurred keloids with surgical excision and postoperative X-ray radiation.
Jae Duck KIM ; Young Jin KIM ; Sung Shin WEE ; Moon Je CHO ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(6):1009-1014
No abstract available.
Keloid*
9.Clinical and Angiographic Outcomes: Subcutaneous Nadroparin versus Ticlopidine after Coronary Stenting.
Kyoung Deok SHIN ; Jei Keon CHAE ; Sung Ki MOON ; Won Ho KIM ; Jae Ki KO
Korean Circulation Journal 1999;29(3):259-265
BACKGROUNG AND OBJECTIVES: It was reported that low molecular weight heparin (LMWH) was more effective than unfractionated heparin in patients with acute coronary syndrome. Recent studies have shown that the pathophysiology of restenosis in stented lesions was different from those of nonstented lesions. Treatment strategies designed to limit cellular proliferation that were ineffective in nonstented lesions may be efficacious in reducing in-stent restenosis. This study was aimed to compare the clinical and angiographic results of LMWH (nadroparin) after coronary stenting with those of conventional ticlopidine regimen. MATERIALS AND METHODS: Patients were eligible for inclusion if they had angina and/or objective evidence of myocardial ischemia, and a significant (>50%) stenosis that was documented on a recent coronary angiogram. After stenting, prospective randomized comparison study was performed. Patients were randomly assigned to either nadroparin (200 IU/kg, sc, bid) or ticlopidine (250 mg bid) plus aspirin (200 mg qd) treatment groups. Repeat coronary angiography (KERN=*)was performed at 236+/-90days after stenting, and quantitative coronary angiographic analysis (QCA) was done. RESULTS: Intracoronary stent implantation was performed in eighty five lesions in eighty one patients (ticlopidine:40, nadroparin:41). There was no significant difference in any baseline clinical/angiographic variables between the two treatment groups. There were no subacute stent thrombosis, infarction and death in both groups. Six-month event-free survival was 36 (90%) in the ticlopidine group and 35 (85.4%) in the nadroparin group. Follow-up quantitative angiographic data such as late loss (1.35+/-0.70 vs 1.32+/-0.69), loss index (0.53+/-0.70 vs 0.56+/-0.23) and restenosis rate (36% vs 25.8%) were not different between ticlopidine and nadroparin groups. CONCLUSION: Effects of nadroparin were not different from those with ticlopidine therapy in the prevention of restenosis and subacute stent thorombosis after coronary stenting. Clinical outcomes between two strategies were similar. Low molecular weight heparin may be an alternative to ticlopidine in patients that ticlopidine cannot be administered because of severe adverse effects.
Acute Coronary Syndrome
;
Aspirin
;
Cell Proliferation
;
Constriction, Pathologic
;
Coronary Angiography
;
Disease-Free Survival
;
Follow-Up Studies
;
Heparin
;
Heparin, Low-Molecular-Weight
;
Humans
;
Infarction
;
Myocardial Ischemia
;
Nadroparin*
;
Prospective Studies
;
Stents*
;
Thrombosis
;
Ticlopidine*
10.Changes of Serum Inhibin Concentration in Controlled Ovarian Hyperstimulation for IVF-ET.
Shin Yong MOON ; Seok Hyun KIM ; Jae Hoon LEE ; Chang Suk SUH
Korean Journal of Obstetrics and Gynecology 1998;41(11):2795-2805
Inhibin is a glycoprotein usually produced by granulosa cell of ovary and is known as regulator of FSH secretion. Inhibin is consisted of two heterodimeric subunit of a, B . There are two distinct molecular forms of the B subunit that exist (BA and BB) and when combined with an a subunit, form inhibin A, and inhibin B, respectively. Ovarian reserve describes women's reproductive potential, which usually decreased according to chronological age. Because useful markers claimed for the prediction of ovarian response during controlled ovarian hyperstimulation for IVF-ET have not been always successful, new biomarker has been investigated. The purpose of this study was to observe the changes in serum and ovarian follicular inhibin A concentration during controlled ovarian hyperstimulation for IVF-ET program and to evaluate the clinical significance of inhibin A as a prognostic marker for assisted reproductive technology outcomes. From Jan 1996 to Dec 1996, 48 patients who underwent IVF-ET were included. In each patient, the Day 3 FSH, LH, E2q were measured in the first month of cycle before commencing GnRH agonist administration, In the stimulation period after pituitary down regulation, blood samples for inhibin A were collected at the day 3, day 7, day of hCG injection, day of oocytes aspiration, and day of embryo transfer. Ovarian follicular inhibin A was collected at the day of oocyte aspiration. Inhibin A concentration was measured using test kit for inhibin A (INHIBIN-EASIA (code 40.134.00), Belgium Medgenix). The changes in serum inhibin A, E2 concentration during IVF-ET program showed increasing pattern throughout controlled ovarian hyperstimulation periods. If the cut-off value of day 3 serum inhibin A determined to 0.28 U/ml, the sensitivity and specificity were 80.0%, 75.0% respectively in predicting the number of oocytes retrieved being more than five. If the cut-off value of peak serum E determined to 1316 pg/ml, the sensitivity and specificity were 89.0%, 100.0% respectively in predicting the number of oocytes retrieved being more than five. In conclusion, measurement of serum inhibin A concentration on the day of starting stimulation (day 3) could be used as a useful marker for predicting the ovarian response in IVF-ET program.
Belgium
;
Down-Regulation
;
Embryo Transfer
;
Female
;
Glycoproteins
;
Gonadotropin-Releasing Hormone
;
Granulosa Cells
;
Humans
;
Inhibins*
;
Oocyte Retrieval
;
Oocytes
;
Ovary
;
Reproductive Techniques, Assisted
;
Sensitivity and Specificity
;
Serum