One hundred fifty-seven patients wha underwent radical hysterectomy and pelvic lymphadenectomy for FIGO stage IB and IIA carcinoma of the cervix between February l975 and May 1987 were retros-pectively analysed to identify specific risk factors associsted with treatment failures. Prognostic factors inciuded clinical stage, histologic cell type, degree of differentiation, size of primary tumor, depth of stromal invasian, lymph-vaseular space invasion, and lymph node metastasis. Treatment results were evaluated according to the recurrence rate and 2-year absolute recurrence-free survival(NED) rate by the prognostie faetors and treatment modalities. Patients with lymph node me tases had a significantly higher incidence of bulky primary(-> 4cm), depth of stromal invasion(> 60% thickness), and lymph-vascular invasion(P<0.005). There was significant difference in the recurrence rate and 2-year, NED rate between cervical carcinoma stage IB and I1A(P <0.005). The pat,ients who had bulky primary tum~or(>4cm) and/or depth of stromal invasion (>60% thickness) had a higher recurrence and lower 2-year NKD rate(P<0.025, P<0.005), Unfortunately, it was not possible to demonstrate that these detrimentel effects could be overeorne by postoperetive radiation. When adjoined for these risk group, traditionally reported poor prognostic factors such as nodal metatasis, cell type and differentiation, lyrnphi-vascular mvasion assume less importance in our studies. In this study, prognosis is most inf1ueneed by clinical stage, depth of stromal invasion, and size of primary tumor,
Cervix Uteri* ; Female ; Humans ; Hysterectomy ; Incidence ; Lymph Node Excision ; Lymph Nodes ; Neoplasm Metastasis ; Prognosis ; Recurrence ; Risk Factors ; Treatment Failure*

No abstract available.

No abstract available.
Chronic Periodontitis* ; Diabetes Mellitus ; Diabetes Mellitus, Type 2* ; Humans* ; Inflammation ; Interleukin-6* ; Pancreatic Elastase*

BACKGROUNDS: A splenectomy is often performed simultaneously with a total gastrectomy for lymph node dissection in gastric cancer. The therapeutic value of a splenectomy in a curative total gastrectomy is controversial. The purpose of this retrospective study is to evaluate the impact of a splenectomy combined with a total gastrectomy on the survival and the postoperative morbidity in gastric cancer. METHODS: From among 343 patients with total gastrectomy for gastric cancer between September 1983 and December 1996, we analyzed 237 patients who underwent a curative resection : 107 patients with a splenectomy and 130 patients without a splenectomy. RESULTS: There were significant differences between the patients with and without a splenectomy with regard to type of cancer, tumor size, and depth of invasion. In those who underwent a splenectomy, the tumor was larger, Borrman type III lesions were more frequent, the depth of invasion was greater, and an advanced stage was more frequent. The 5-year survival rate of the patients with a splenectomy was insignificantly less than that of those without splenectomy (50.6% vs. 57.7%, P> 0.05). There was no significant difference in the survival time according to the stage. Postoperative complications occurred more commonly in the patients of a splenectomy than those without a splenectomy (22.4% vs. 14.6%). CONCLUSIONS: We conclude that a splenectomy did not affect the prognosis for patients with gastric cancer and that efforts should be made to preserve the spleen during a gastrectomy. A prospective study should be done to better define the relationship between a splenectomy and the survival time of patients with gastric cancer.
Gastrectomy* ; Humans ; Lymph Node Excision ; Postoperative Complications ; Prognosis ; Retrospective Studies ; Spleen ; Splenectomy* ; Stomach Neoplasms* ; Survival Rate

No abstract available.

No abstract available.
Diagnosis* ; Ultrasonography*

No abstract available.
Diagnosis* ; Ultrasonography*

The determination of motor nerve conduction velocity is an important part to electrodiagnosis. Its value as neurophysiologic investigative procedure has been known for many years, and recently it has been utilized as a chinical diagnostic technic. Its most valuable role is differentiating between those conditions which affect the axon primarily and those which affect the anterior horn cell. Many factors such as temperature in the vicinity of the nerve, diameter of the axon, degree of myelinization, age of the patient, local environment of the nerve and intensity of electrical stimulation have been demonstrated to affect the rate of propagation of impulses along motor fibers. Pathologic conditions affecting the axon usually alter the excitability along involved segments and, therefore, result in reduced conduction velocity. The purpose of this study was to determine the normal data of the motor nerve conduction velocities of median, ulnar, tibial and peroneal nerves in Korean. 1. The motor nerve conduction velocities of median, ulnar, peroneal and tibial nerves were 61.54±6.95 (46.7–94.2) m/sec, 61.74±7.28 (45.6–95.0)m/sec, 48.80±5.54 (38.8–69.9) m/sec, 47.39±4.85 (36.2–64.2 m/sec respectively. 2. The condition velocity in the upper extremities has been found 13.5 m/sec faster than in the lower extremities. 3. A significant decline in motor nerve conduction velocities was noted in the over 60 year old age group. 4. There were significant differences between the sexes.
Anterior Horn Cells ; Axons ; Electric Stimulation ; Electrodiagnosis ; Humans ; Lower Extremity ; Myelin Sheath ; Neural Conduction ; Peroneal Nerve ; Tibial Nerve ; Upper Extremity

No abstract available.

No abstract available.