1.Comparison of Magnetic Resonance Imaging and Discography in the Diagnosis of Internal Disc Derangement.
The Journal of the Korean Orthopaedic Association 2000;35(1):127-134
PURPOSE: To compare the effectiveness of Magnetic Resonance Imaging and discography in the diagnosis of internal disc derangement (IDD) . MATERIALS AND METHODS: This study was confined to 90 discs of 30 patients diagnosed as IDD by MRI & disco-CT. We compared the pain nature of discogram, degree of annular tear in the disco-CT and degree of disc degeneration in MRI. The presence of HIZ (High Intensity Zone) in MRI was also compared with the pain of discogram. RESULTS: Those discs with more severe annular tears in the disco-CT showed more definite pain pattern in the discogram. More degeneration in the MRI was also correlated with more anatomical deterioration in disco-CT. Of the 27 discs with normal MRI, 6 (22%) showed severe pain provocation in discography. Of the 63 discs with degeneration in MRI, 14 (22%) showed no pain provocation in discography. Of all discs, HIZ was present in 16% (15/90) . When HIZ was present in a disc of a symptomatic patient, the possibility of it being a painful disc was 93%. CONCLUSION: In the diagnosis of IDD, MRI was helpful is seeing the degree of disc degeneration to rule out disc herniation or spinal stenosis. But the discogram is considered the only way for definite diagnosis of painful discs.
Diagnosis*
;
Humans
;
Intervertebral Disc Degeneration
;
Magnetic Resonance Imaging*
;
Spinal Stenosis
2.A Clinical Study of Periventricular-Intraventricular Hemorrhage in Very Low Birth Weight Infants.
Myoung Jae CHEY ; Young Pyo CHANG ; Jung Hwan CHOI ; Yong Seung HWANG ; Chong Ku YUN ; In One KIM ; Kyung Mo YEON
Journal of the Korean Pediatric Society 1990;33(10):1341-1352
No abstract available.
Hemorrhage*
;
Humans
;
Infant*
;
Infant, Very Low Birth Weight*
3.Mitral Regurgitation after Percutaneous Balloon Mitral Valvuloplasty(PMV): Results and Relationships to Valve Morphology.
Seung Jung PARK ; Seung Yun CHO ; Won Heum SHIM ; Woong Ku LEE ; Sung Soon KIM ; Seung Jae TAHK ; Ik Mo CHUNG ; Kyung Kwon PAIK
Korean Circulation Journal 1988;18(3):319-327
To evaluate the change in valvular morphology and occurence and severity of mitral regurgitation produced by PMV, 45 patients(33 women and 12 men,mean age 38+/-10 years) were studied using two-dimensional(2-D) and Doppler echocaediography before and 1-2 days after this procedure. Mitral valve area after PMV increased in all patients, from 0.9+/-0.2 to 1.8+/-0.4cm2(P<0.0001). In valve area estimation, the correlation between Gorlin`s method and 2-Dechocardiography was better(r=0.61, p<0.0001) than that between Gorlin`s method and Doppler pressure halftime(r=0.38, P<0.01) before valvuloplasty, but after the procedure Gorlin`s and 2-D image valve area correlated less well(r=0.33, P<0.05) than Gorlin`s-Doppler pressure halftime correlation(r=0.46, P<0.002). Before PMV, 37 patients had no mitral regurgutation, 7 had grade 1 and 1 had grade 2 mitral regurgutation. After PMV, new mitral regurgutation occurred in 14 patients, increased in severity in 5 patients and so mitral regurgutation newly developed or increased in severity in 19(42%) patients. There were no differences between the patients with and those without an increase in mitral regurgutation after PMV, in age, sex, caediac rhythm, initial mitral valve area, increase in mitral valve area and fluoroscopic calcification. However, morphologic characteristics especially mobility(P<0.01) and thickening(P<0.05) of mitral leaflets were better pressured, and EBDA/BSA(effective balloon dilating area/body surface area) was significantly smaller(P<0.02) in patients without an increase in mitral regurgutation. Thus, an increase in mitral regurgutation after PMV might be related to the features of valve morphology especially and thickand EBDA/BSA.
Female
;
Humans
;
Mitral Valve
;
Mitral Valve Insufficiency*
;
Mitral Valve Stenosis
4.A Case of Vaginal Cavernous Hemangioma in Pregnancy.
Jae Deok LEE ; Geon Su KIM ; Heung Mo KOO ; In Mo KU ; Young Chae KO ; Young Il LEE ; Tae Il CHO ; You Mee KANG
Korean Journal of Obstetrics and Gynecology 2003;46(5):1047-1049
To our knowledge, only one case of vaginal cavernous hemangioma in pregnancy has been reported all over the world and there is no report in Korea. The authors have experienced one case of vaginal cavernous hemangioma in pregnancy and report our case with a brief review of literature.
Hemangioma, Cavernous*
;
Korea
;
Pregnancy*
;
Vagina
5.Serological Immunity to Diphtheria among Korean Population.
Bok Kwon LEE ; Jae Ku PARK ; Jae Il YOO ; Kwang Hoon SHIN ; Young Mo SOHN ; Ki Dong PARK ; Chong Goo LEE ; Joung Soon KIM
Korean Journal of Infectious Diseases 1998;30(3):278-283
BACKGROUND: Diphtheria epidemics in Russia have spread to all the other independent states of the former Soviet Union and East European countries around 1990s. One of the most important measures in preventing diphtheria is to maintain high levels of immunity in the population. We studied the diphtheria antibody levels of 1,086 participants to investigate herd immunity in Korea. METHODS: The tested 1,086 serum specimens were collected from healthy individuals from September 1995 to March 1996. Diphtheria antitoxin titers were measured by a micro cell culture method using Vero cells. Antibody titer of 0.01 IU/ml to neutralize diphtheria toxin is an internationally accepted protective level. RESULTS: We studied the diphtheria antitoxin titer levels of 1,086 cases consisting of 579 males and 507 females. The proportion of protective antitoxin level to diphtheria is 69.2%. Diphtheria antitoxin levels showed no significant difference between males and females. The highest seropositive rate was observed in the 5 to 9-year old age group(95.8%). The seropositivity rate declined with age. The lowest seropositive rate was observed in the 20~39 years of age, maximally 43.4 %. Over 40 years of age, the seropositive rates increased again. CONCLUSION: The antibody titers in the Korean population declined from 95.8% to below 50% with age in the 1~39 year-old age group. To maintain the rate of population with protective antibodies to diphtheria, we recommend Td booster immunization to adults with low antitoxin titers and continuous survey for antitoxin titers.
Adult
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Antibodies
;
Cell Culture Techniques
;
Child
;
Diphtheria Antitoxin
;
Diphtheria Toxin
;
Diphtheria*
;
Female
;
Humans
;
Immunity, Herd
;
Immunization, Secondary
;
Korea
;
Male
;
Russia
;
USSR
;
Vero Cells
6.A Case of Hydrogen Peroxide Induced Colitis.
Seong Kwoo CHO ; Young Kwan KIM ; Young Rock LEE ; Young Ho KIM ; Sang Mo PARK ; So Young KU ; Jae Kwon KIM ; Yeon Soo LEE ; Kyoung Ho KIM
Korean Journal of Gastrointestinal Endoscopy 1999;19(4):659-666
Hydrogen peroxide has been used for various medical purposes and also recommended in the disinfection process for endoscopes. However, hydrogen peroxide as a cause of chemical colitis or disinfectant colitis has been infrequently reported. The endoscopic findings of hydrogen peroxide induced colitis revealed pseudomembranous-like enteritis such as white plaques, erythema, foamy liquid, patchy, granularity, and ulcerations, resulting from effervescence caused by the release of oxygen from the breakdown of hydrogen peroxide. A 36 year-old single male, who had 30 ml of 3% hydrogen peroxide inserted into his anus the day before due to sexual reasons, was hospitalized as a result of suffering from hematochezia, tenesmus, and lower abdominal pain. Colonoscopy revealed discrete or confluent white plaques adherent to the colonic mucosa, severe erythema on the surrounding mucosa, patchy granularity, and scattered ulcerations up to 28 cm from the anal verge. Pathologic finding revealed inflammatory cells infiltration, variable sized vacuoles, vascular congestion, hemorrhage, fibrin deposition and ulcerations with regenerating epithelium in the lamina propria, consistent with acute mucosal injury caused by hydrogen peroxide. A case of hydrogen peroxide induced colitis is herein reported.
Abdominal Pain
;
Adult
;
Anal Canal
;
Colitis*
;
Colon
;
Colonoscopy
;
Disinfection
;
Endoscopes
;
Enteritis
;
Epithelium
;
Erythema
;
Estrogens, Conjugated (USP)
;
Fibrin
;
Gastrointestinal Hemorrhage
;
Hemorrhage
;
Humans
;
Hydrogen Peroxide*
;
Hydrogen*
;
Male
;
Mucous Membrane
;
Oxygen
;
Ulcer
;
Vacuoles
7.A Case of Meckel's Enterolith.
Young Kwan KIM ; Young Ho KIM ; Young Rock LEE ; Seong Kwoo CHO ; Sang Mo PARK ; So Young KU ; Jae Kwon KIM ; Yeon Soo LEE ; Kyoung Ho KIM
Korean Journal of Gastrointestinal Endoscopy 1999;19(4):643-651
The term enterolith refers to concretions formed within the gastrointestinal tract. Enteroliths are thought to result from stasis and are usually found proximal to an area of stricture or within diverticulum. Meckel's diverticulum occurs in 1% to 3% of the population at autopsy and is the most common congenital anomaly of the gastrointestinal tract. Common complications of Meckel's diverticulum include hemorrhage, infection, inflammation, and intussusception. However, enterolith formation in a Meckel's diverticulum, which referred to as Meckel's enterolith, is rare. A 58-year-old female who experienced constipation and low abdominal pain for 20 years, was admitted due to severe low abdominal pain for 3 days. A 3 2 cm sized, lozenge-shaped radiopaque stone with peripheral dense calcification and radiolucent center, located between two areas of stricture in the distal ileum, was observed in abdominal radiograph, abdominal sonogram, small bowel study, and CT scan. Pathologic findings after surgery reveal an enterolith in Meckel's diverticulum without ectopic gastric mucosa. The case of Meckel's enterolith is herein reported.
Abdominal Pain
;
Autopsy
;
Constipation
;
Constriction, Pathologic
;
Diverticulum
;
Female
;
Gastric Mucosa
;
Gastrointestinal Tract
;
Hemorrhage
;
Humans
;
Ileum
;
Inflammation
;
Intussusception
;
Meckel Diverticulum
;
Middle Aged
;
Tomography, X-Ray Computed
8.A Case of Pulmonary Cryptococcosis Diagnosed by Percutaneous Needle Aspiration and Biopsy.
Hyung Won YANG ; Kyung Hwan KIM ; Jung Eun CHOI ; Eun Kyung MO ; In Sook WOO ; Myung Jae PARK ; Myung Ku LEE ; K Seuk JUNG ; Hae Jung PARK ; Hye Kyung AN
Korean Journal of Infectious Diseases 1997;29(2):159-164
Cryptococcosis is a systemic infection caused by the yeast-like fungus Cryptococcus neoformans, involving central nervous system, lung, skin, prostate and bone. We have experienced a case of pulmonary cryptococcosis without involving other organ in healthy person. A previously healthy 74-year old female patient was admitted due to cough, sputum, general weakness and perioral numbness. As compared with chest PA that was taken 1 year before admission, single nodule of left upper lobe was enlarged slightly. CT-guided needle aspiration and biopsy were done and cryptococcosis was diagnosed by pathology. After central nervous system infection was excluded, oral fluconazole was given for 12 weeks. The cryptococcoma was nearly disappeared with 12-weeks' treatment and did not relapse until 6 month later.
Aged
;
Biopsy*
;
Central Nervous System
;
Central Nervous System Infections
;
Cough
;
Cryptococcosis*
;
Cryptococcus neoformans
;
Female
;
Fluconazole
;
Fungi
;
Humans
;
Hypesthesia
;
Lung
;
Needles*
;
Pathology
;
Prostate
;
Recurrence
;
Skin
;
Sputum
;
Thorax
9.Erratum: Efficient gene delivery in differentiated human embryonic stem cells. Exp Mol Med 2005;37:36-44.
Jae Hwan KIM ; Hyun Jin DO ; Seong Jun CHOI ; Hyun Jung CHO ; Kyu Hyung PARK ; Heung Mo YANG ; Sang Hwa LEE ; Dong Ku KIM ; Kyu Bum KWACK ; Sun Kyung OH ; Shin Yong MOON ; Kwang Yul CHA ; Hyung Min CHUNG
Experimental & Molecular Medicine 2006;38(5):589-589
The authors would like to amend a reference (Lee et al., 2003) that was cited in "Cell culture" section of "Materials and Methods". Instead of "(Lee et al., 2003)", we would like to change the reference to "(Kim et al., 2003)". In "References", it also needs to include the following reference. Kim YY, Seol HW, Ahn HJ. Temporal expression of differentiation markers in embryoid bodies from various human embryonic stem cell line. International Society for Stem Cell Research 1st Annual Meeting, Washington, DC. U.S.A. June 8-11, 2003, Abstract No. 35. The authors apologize for any inconvenience.
10.Expression of p63 and p53 Proteins in Premalignant Lesions and Invasive Squamous Cell Carcinomas of the Uterine Cervix.
Geon Su KIM ; Jae Deok LEE ; In Mo KU ; Young Chae KO ; Hee LEE ; Kee Won YANG ; Won Il CHOI ; Young Il LEE ; Tae Jin LEE
Korean Journal of Obstetrics and Gynecology 2003;46(10):1905-1911
OBJECTIVE: p63 is a member of the p53 gene family. The main aim of this study was to compare p63 and p53 expression in precancerous lesions and invasive squamous cell carcinoma of the uterine cervix. METHODS: Total 81 formalin-fixed, paraffin-embedded sections of low-grade squamous intraepithelial lesion (22 cases), high-grade squamous intraepithelial lesion (42 cases) and invasive squamous cell carcinomas (17 cases) in the uterine cervix were stained by immunohistochemistry for expression of p63, p53 and topoisomerase II-alpha. RESULTS: p63 was statistically significant higher immunoreactivity according to progression of uterine cervical squamous lesions, but p53 was not significant. No statistical correlation was found between p63 and p53. Topoisomerase II-alpha index was statistically significant higher according to increase of p63 expression. CONCLUSION: These findings suggest that the expression of p63 protein may play a roles in progression and proliferative activities of the uterine cervical squamous lesions.
Carcinoma, Squamous Cell*
;
Cervix Uteri*
;
Female
;
Genes, p53
;
Humans
;
Immunohistochemistry