1.Impaired Endothelium-Dependent Responsiveness in Porcine Coronary Arteries with Chronic Regenerated Endothelium.
Seung Jung PARK ; Seong Wook PARK ; Jae Joong KIM ; Jae Kwan SONG ; Jong Koo LEE ; Paul M VANHOUTTE
Korean Circulation Journal 1994;24(1):118-134
No abstract available.
Coronary Vessels*
;
Endothelium*
2.A Case of Measles Pneumonia Complicated by Subcutaneous Emphysema and Pneumomediastinum in an 18-year-old Patient.
Jae Hyeong PARK ; Yun Jung LEE ; Ho Hyung KANG ; Sun Jong KIM ; Y S KOH ; C M LIM
Tuberculosis and Respiratory Diseases 2001;51(3):275-280
A 18 year-old man presented with dyspnea and a swelling of the neck. On physical examination, maculopapular rashes were noted on the face and the whole body and crepitus was noted at the thorax and upper arms. His chest X-ray showed bilateral interstitial infiltrates of the lung, pneumomediastinum and subcutaneous emphysema. On serologic examination, measles IgM was positive. Under the diagnosis of measles pneumonia, the patient was treated with oral ribavirin, which resulted in a complete resolution of the pneumomediastinum, subcutaneous emphysema, pneumonic infiltrate, and subjective symptoms of dyspnea and swelling of the neck in 7 days. Here we report this case with a brief review of the relevant literature.
Adolescent*
;
Arm
;
Diagnosis
;
Dyspnea
;
Exanthema
;
Humans
;
Immunoglobulin M
;
Lung
;
Measles*
;
Mediastinal Emphysema*
;
Neck
;
Physical Examination
;
Pneumonia*
;
Ribavirin
;
Subcutaneous Emphysema*
;
Thorax
3.In vitro Inhibition Effect of Plant Extracts, Urine, Fertilizers and Fungicides on Stem Rot Pathogen of Sclerotium rolfsii.
Shahidul ALAM ; M Rafiqul ISLAM ; Montaz Ali SARKAR ; M S ALAM ; Kee Don HAN ; Jae Ouk SHIM ; Tae Soo LEE ; Min Woong LEE
Mycobiology 2004;32(3):128-133
Twenty plant extracts were tested against mycelial growth, sclerotium formatiom and dry weight of mycelium with sclerotia of Sclerotium rolfsii Sacc. The highest(90 mm) mycelial growth was measured in Adhatoda vasica, Tegetes erecta, Allium cepa, and Curcuma longa. The lowest(25 mm) was in Azadirachta indica. No mycelial growth was found in any concentration of cow, buffalo, and goat urine. The highest(90 mm) and the lowest(15 mm) mycelial growth were measured in Biomil and Urea, respectively. No mycelial growth was observed in Zinc. The highest(60 mm) and the lowest(2 mm) mycelial growth were recorded in Macuprex(Dodine; 65% WP) and Boron(100% Boric acid and 17% Boron) respectively. Mycelial growth was totally inhibited in Rovral(Iprodione; 50% WP).
Justicia
;
Azadirachta
;
Buffaloes
;
Curcuma
;
Fertilizers*
;
Goats
;
Mycelium
;
Onions
;
Plant Extracts*
;
Plants*
;
Urea
;
Zinc
4.Effects of Dietary Habits on the Serum Isoflavones Levels.
Young Suk LEE ; Sang Cheol LEE ; Wun Jae KIM
Korean Journal of Urology 2006;47(7):773-778
PURPOSE: Recent studies have suggested that isoflavones have an inverse correlation with the risk of prostate cancer. In addition, the serum isoflavones levels are thought to be decided not only by the level of intake of isoflavones, but also by the metabolic processes or the genetic abilities required for ingestion of isoflavones. So, we conducted this study to determine the effects of dietary habits on the serum isoflavones levels. MATERIALS AND METHODS: One hundred age- and community-matched healthy men between the ages of 10 and 59 years were interviewed using a food frequency questionnaire that was developed and validated for Korean populations. The individuals' dietary habits during the previous one-year period and the foods they ingested during the previous one-week period before blood sampling were assessed. The serum concentrations of isoflavones were analyzed by the reversed-phase high performance liquid chromatography-multiple reaction ion monitoring-mass spectrometry method (HPLC-MS), (SRL Co. Tokyo, Japan). RESULTS: The genistein and daidzein levels were significantly correlated with age (p=0.026 and p=0.016, respectively), but the equol level was not (p=0.091). The foods associated with the genistein level were unmilled rice, beans, garlic and etc. The foods significantly related to the daidzein level were unmilled rice, garlic and etc. Of the foods ingested during the previous one-week period, fermented soybean soup, garlic, strawberries and mung-bean pancakes were associated with the equol level. CONCLUSIONS: The genistein and daidzein levels were associated with usual dietary habits, but the equol level was related to the short-period food consumption. Changes in dietary habit might induce significant changes in the genistein and daidzein levels.
Eating
;
Equol
;
Fabaceae
;
Food Habits*
;
Fragaria
;
Garlic
;
Genistein
;
Humans
;
Isoflavones*
;
Male
;
Metabolism
;
Prostatic Neoplasms
;
Surveys and Questionnaires
;
Soybeans
;
Spectrum Analysis
5.A Combined Closing Wedge Distal Femoral Osteotomy and Medial Reefing Procedure for Recurrent Patellar Dislocation with Genu Valgum.
Chong Bum CHANG ; Gautam M SHETTY ; Jong Seong LEE ; Young Chan KIM ; Jae Ho KWON ; Kyung Wook NHA
Yonsei Medical Journal 2017;58(4):878-883
PURPOSE: Recurrent patellar dislocation is often associated with genu valgum. The purpose of this study was to analyze the short-term results of single-incision, closing-wedge distal femoral osteotomy (CWDFO) combined with medial reefing and lateral release for recurrent patellar instability with genu valgum. MATERIALS AND METHODS: Combined CWDFO/medial reefing/lateral release was performed on 10 knees. Clinical evaluation was based on pre- and postoperative Knee Society Score (KSS) and Kujala patellofemoral score. Radiographic evaluation was performed with reference to the weight-bearing line (WBL), the femorotibial angle (FTA), and the mechanical lateral distal femoral angles in the knee-standing view. RESULTS: At a mean follow-up of 20±11.7 months (range, 12–42 months), KSS scores improved significantly, from 46.7±5.2 preoperatively to 87±4.4 postoperatively (p<0.001), as did the Kujala score, from 44±8 preoperatively to 86.6±6.8 postoperatively (p<0.001). The WBL decreased significantly, from 76±7% preoperatively to 41±11% postoperatively (p<0.001). The FTA was improved significantly, from 12.7±1.7° preoperatively to 4±4° postoperatively (p<0.001), as was the mLDFA, from 83±4° preoperatively to 91±1.3° postoperatively (p<0.001). CONCLUSION: Use of single-incision CWDFO combined with medial reefing and lateral release prevents patellar dislocation, corrects deformity, and improves clinical outcomes.
Congenital Abnormalities
;
Follow-Up Studies
;
Genu Valgum*
;
Knee
;
Osteotomy*
;
Patellar Dislocation*
;
Weight-Bearing
6.Stenosis of calcified carotid artery detected on Panoramic Radiography.
So Yang CHO ; Won Mann OH ; Suk Ja YOON ; Woong YOON ; Jae Seo LEE ; Juan M PALOMO ; Byung Cheol KANG
Korean Journal of Oral and Maxillofacial Radiology 2009;39(3):157-161
PURPOSE: This study aimed to investigate the luminal stenosis of the internal carotid artery with calcification detected on panoramic radiographs. MATERIALS AND METHODS: This study used fifty carotid arteries of 36 dental patients whose panoramic radiograph and computed tomography angiography (CTA) revealed the presence of carotid artery calcification. A neuroradiologist interpreted CTA to determine the degree of stenosis of the internal carotid arteries. The degree of stenosis was stratified in four stages; normal (no stenosis), mild stenosis (1-49%), moderate stenosis (50-69%) and severe stenosis (70-99%). RESULTS: Among the fifty carotid arteries with calcification detected on both panoramic radiography and CTA, 20carotid arteries (40%) were normal, 29 carotid arteries (18%) had mild stenosis, 1 carotid artery (2%) had moderate stenosis, and there was none with severe stenosis. CONCLUSION: Sixty percent of the carotid arteries with calcification detected on both panoramic radiography and CTA had internal luminal stenosis, and two percent had moderate stenosis. When carotid atheroma is detected on panoramic radiograph, it is possible that the dental patient has luminal stenosis of the internal carotid artery.
Angiography
;
Arteries
;
Carotid Arteries
;
Carotid Artery, Internal
;
Constriction, Pathologic
;
Humans
;
Phenobarbital
;
Plaque, Atherosclerotic
;
Radiography, Panoramic
7.Fine Needle Aspiration Cytology of Metastatic Epithelial-Myoepithelial Carcinoma of the Scalp: A Case Report.
Mi Seon KWON ; Seung Sook LEE ; Jae Soo KOH ; Jin Haeng CHUNG
Korean Journal of Cytopathology 2000;11(2):93-97
Epithelial-myoepithelial carcinoma is an uncommon, low grade malignant epithelial neoplasm and metastasis is exceedingly rare. This article highlights the fine needle aspiration cytology(FNAC) of a case of metastatic epithelial-myoepithelial carcinoma of the scalp. A 51-year-old female presented with the left parietotemporal scalp mass two months after the left parotidectomy for epithelial-myoepithelial carcinoma. FNAC from the scalp mass showed a biphasic population of ductal epithelial and myoepithelial origin. These epithelial aggregates were numerous and formed a distinct three dimensional architecture in the background of numerous naked nuclei. The three dimensional architectures were predominantly composed of tightly cohesive eosinophilic ductular epithelial cells which tended to aggregate, overlap, and form tubules. Clear myoepithelial cells in three dimensional tissue fragment were inapparent and a few were attached to the periphery of the fragments. A few myoepithelial cells with clear abundant vaculoated cytoplasm were found in the foamy background. The cytological diagnosis was metastatic epithelial-myoepithelial carcinoma. The histologic findings of the scalp mass were those of typical epithelial-myoepithelial carcinoma. Cytologic distinction of epithelial-myoepithleial carcinoma, pleomorphic adenoma, and adenoid cystic carcinoma may be very difficult but careful attention to clinical features and cellualr details can classify these neoplasms correctly.
Adenoma, Pleomorphic
;
Biopsy, Fine-Needle*
;
Carcinoma
;
Carcinoma, Adenoid Cystic
;
Cytoplasm
;
Diagnosis
;
Eosinophils
;
Epithelial Cells
;
Female
;
Humans
;
Middle Aged
;
Neoplasm Metastasis
;
Scalp*
8.Conservative Management of Freiberg Disease with Shoe Modification and Insole:A Case Report with 2-Year Follow-up
Jin W oo SUH ; Chul-Hyun PARK ; Kyung Jae YOON ; Yong-Taek LEE
The Korean Journal of Sports Medicine 2023;41(1):45-49
Freiberg disease, known as a Freiberg infraction, is an uncommon disorder of the second metatarsal head of the foot. Conservative treatment is recommended as initial management to relieve symptoms and minimize epiphyseal deformity. However, due to the rarity of this disorder, there have been few reports of long-term clinical and radiologic follow-ups of Freiberg disease treated with conservative treatment. We report Freiberg disease treated with conservative management including modification of shoe and insole. A 24-year-old woman presented with right forefoot pain. In plain radiography, the sunken appearance of the metatarsal head and periarticular spurring was observed. The articular cartilage was intact in magnetic resonance imaging (MRI), corresponding to Smillie’s stage 3 and Thompson’s type 2. We prescribed carbon fiber insert, customed semirigid insole with metatarsal dome and rocker-bottom shoe to relieve pressure under the metatarsal heads. Freiberg disease maintained a well-tolerable condition during 2-year follow-up period without further progression in MRI.
9.Assessment of Cognitive Impairment in a Mouse Model of High-Fat Diet-Induced Metabolic Stress with Touchscreen-Based Automated Battery System.
Saeram LEE ; Jong Youl KIM ; Eosu KIM ; KyoungYul SEO ; Youn Jae KANG ; Jae Young KIM ; Chul Hoon KIM ; Ho Taek SONG ; Lisa M SAKSIDA ; Jong Eun LEE
Experimental Neurobiology 2018;27(4):277-286
Obesity-related metabolic disorders can affect not only systemic health but also brain function. Recent studies have elucidated that amyloid beta deposition cannot satisfactorily explain the development of Alzheimer's disease (AD) and that dysregulation of glucose metabolism is a critical factor for the sporadic onset of non-genetic AD. Identifying the pathophysiology of AD due to changes in brain metabolism is crucial; however, it is limited in measuring changes in brain cognitive function due to metabolic changes in animal models. The touchscreen-based automated battery system, which is more accurate and less invasive than conventional behavioral test tools, is used to assess the cognition of mice with dysregulated metabolism. This system was introduced in humans to evaluate cognitive function and was recently back-translated in monkeys and rodents. We used outbred ICR mice fed on high-fat diet (HFD) and performed the paired associates learning (PAL) test to detect their visual memory and new learning ability loss as well as to assess memory impairment. The behavioral performance of the HFD mice was weaker than that of normal mice in the training but was not significantly associated with motivation. In the PAL test, the average number of trials completed and proportion of correct touches was significantly lower in HFD mice than in normal diet-fed mice. Our results reveal that HFD-induced metabolic dysregulation has detrimental effects on operant learning according to the percentage of correct responses in PAL. These findings establish that HFD-induced metabolic stress may have an effect in accelerating AD-like pathogenesis.
Alzheimer Disease
;
Amyloid
;
Animals
;
Behavior Rating Scale
;
Brain
;
Cognition
;
Cognition Disorders*
;
Diet, High-Fat
;
Glucose
;
Haplorhini
;
Humans
;
Learning
;
Memory
;
Metabolism
;
Mice*
;
Mice, Inbred ICR
;
Models, Animal
;
Motivation
;
Rodentia
;
Stress, Physiological*
10.Arthonia dokdoensis and Rufoplaca toktoana – Two New Taxa from Dokdo Islands (South Korea)
Sergij KONDRATYUK ; László LőKöS ; Josef HALDA ; Beeyoung Gun LEE ; Seol Hwa JANG ; Jeong Jae WOO ; Jung Shin PARK ; Soon Ok OH ; Sang Kuk HAN ; Jae Seoun HUR
Mycobiology 2019;47(4):355-367
Arthonia dokdoensis sp. nov., a lichenicolous fungus from the subcosmopolitan Arthonia molendoi complex growing on crustose thalli of species of the genus Orientophila (subfamily Xanthorioideae, Teloschistaceae), as well as the lichen species Rufoplaca toktoana sp. nov. (subfamily Caloplacoideae, Teloschistaceae) similar to Rufoplaca kaernefeltiana, both from Dokdo Islands, Republic of Korea, are described, illustrated, and compared with closely related taxa. In the phylogenetic tree of the Arthoniaceae based on 12S mtSSU and RPB2 gene sequences, the phylogenetic position of the A. dokdoensis and the relationship with the A. molendoi group are illustrated, while the position of the newly described R. toktoana is confirmed by phylogenetic tree based on ITS nrDNA data.