Cytomegalovirus colitis has been reported infrequently in patients with underlying inflammatory bowel disease, and usually in those who are taking corticosteroid drugs. It has been implicated as a possible exacerbating factor of ulcerative colitis. We experienced a case of cytomegalovirus colitis developed in patient with ulcerative colitis during corticosteroid therapy. So we report the case with a brief review of literatures.
Colitis* ; Colitis, Ulcerative* ; Cytomegalovirus ; Humans ; Inflammatory Bowel Diseases ; Ulcer*

BACKGROUND/AIMS: Experimental studies using porcine non- heart beating donors to ameliorate graft injuries in liver transplantation has been conducted. Recently, it has been reported that cellular calcium may have an important role in ischemic injury, which consists of damage during ischemia and impairment at the time of reperfusion. therefore, it is possible that calcium channel blocker might prevent warm ischemic injury of the graft in liver transplantation when administered to the donor before harvesting and to the recipient at reperfusion. the purpose of this study was to investigate the protective effect of a calcium channel blocker diltiazem (DTZ) on hepatic ischemic injury using a porcine model. METHODS: Twenty pigs weighing 20 to 30 kg were enrolled in this study. Cardiac death was induced by direct cardiac injection of potassium chloride. The perfusion of UW (University of Wisconsin) solution started after 30 min of cardiac arrest. Orthotopic liver transplantation was perforated. Group A (experimental group) was administrated of DTZ at a dose of 70microgram/kg bolus iv injection before hepatic ischemia, perfused of 70microgram/L in UW solution and thereafter infused continuously 70microgram/L in 5% dextrose solution. RESULTS: Two ones death occurred among the ten transplant pigs. 24 hour survival rates were 80%. DTZ administrated group showed the hepatic blood flow and arterial ketone body ratio better compared with untreated controls (p<0.05). In addition, the increase of plasma lactate level was suppressed after ischemia (p<0.05). CONCLUSION: Our results suggest that DTZ has a protective effect on ischemic induced hepatic damage and might be useful in the prevention of primary graft failure caused by warm ischemia in liver transplantation.
Calcium ; Calcium Channels ; Death ; Diltiazem ; Glucose ; Heart ; Heart Arrest ; Humans ; Ischemia ; Lactic Acid ; Liver Transplantation* ; Liver* ; Perfusion ; Plasma ; Potassium Chloride ; Reperfusion ; Survival Rate ; Swine ; Tissue Donors* ; Transplants ; Warm Ischemia

Malignant coloenteric fistula is a rare complication of colon cancer. Colon carcinoma is the most common etiology of this entity. Clinical features are diarrhea, weight loss, anemia and feculent vomiting. The diagnosis is most often made by barium enema examination. The primal therapy is operation. We present a case of a 51-year old male in whom a coloenteric fistula caused by transverse colonic carcinoma. He complained of abdominal pain, diarrhea and dizziness. UGI series demonstrated a fistulous track between colon and small bowel. On abdominal CT examination, a mass involving hepatic flexure of colon with a fistulous tract and metastatic nodules in right lobe of liver were found. Colonoscopy revealed a circumferential mass and the orifice of the fistula. The patient refused operation and expired one month after discharge.
Abdominal Pain ; Anemia ; Barium ; Colon ; Colon, Transverse ; Colonic Neoplasms ; Colonoscopy ; Diagnosis ; Diarrhea ; Dizziness ; Enema ; Fistula* ; Humans ; Liver ; Male ; Middle Aged ; Tomography, X-Ray Computed ; Vomiting ; Weight Loss

PURPOSE: To evaluate the color Doppler imaging patterns of hepatoma, hemangioma, and metastasis. MATERIALS AND METHODS: The study comprised 37 patients with liver mass lesions: 12 patients had hepatoma, 15 had hemangiomas and10 had metastatic liver cancers. All 37, who showed hepatic mass on gray scale ultrasonogrphy, were analyzed prospectively. Color mapping of tumors was performed for these patients, and the fastest or next fastest vessel was spectrally analysed to show blood pattern and to measure peak velocity. RESULTS: In all the 12 patients with hepatoma, spectral analysis revealed exteusive pulsating arterial blood flow within the tumor ; peak velocities were 7~65cm/sec(mean 34cm/sec). In ten hemangiomas(66%) color mapping revealed blood flow within the tumor and spectral analysis revealed this possibility in eight of the ten tumors. In none of these patients was a pulsating continous wave observed ; peak velocity was 5~21cm/sec(mean 12.8cm/sec). In no mestastatic tumors was blood flow observed. CONCLUSION: Color Doppler imaging is helpful in the differentiation of hepatoma, hemangioma, and metastatic tumor in the liver.
Carcinoma, Hepatocellular ; Hemangioma ; Humans ; Liver ; Liver Neoplasms ; Neoplasm Metastasis

We report a case of prolonged extreme reactive thrombocytosis in a post-splenectomy patient with hereditary spherocytosis. A 29-year-old female patient presented with gall stones detected incidentally by abdominal ultrasonography. Her laboratory findings showed hemolytic anemia with spherocytosis on the peripheral blood smear and increased osmotic fragility. She was diagnosed with hereditary spherocytosis and underwent a laparoscopic cholecystectomy and splenectomy. After undergoing surgery, the hemolytic anemia was resolved but thrombocytosis was newly detected. Nineteen months after the splenectomy, the thrombocytosis was still persistent and extremely high. To our knowledge, this is the first report of a prolonged extreme reactive thrombocytosis after a splenectomy in Korea.
Adult ; Anemia, Hemolytic ; Cholecystectomy, Laparoscopic ; Female ; Gallstones ; Humans ; Korea ; Osmotic Fragility ; Spherocytosis, Hereditary ; Splenectomy ; Thrombocytosis