This study was conducted to observe immunological abnormalities, vscular changes and abnormal maturation, pathway of keratinocyte in the psoriasis, by comparing drposits of IgG, fibrinogen(FG) and fibronectin(FN) in the invnlved and uninvolved skin of 19 psoriaics before treatment, the involved skin of 12 among the above patients after treatment, and the skin of 8 normal controls. The study was carried out by using direct immunofluorescence technique with anti-IpG, anti-FG, anti-FN antibodies. The results are summarized as follows: 1. In the uninvolved skin of 19 psoriatics before treatment, no depasition of IgG was observed while deposition of FG was present at the dermo-epidermal junction in 5.3% of the patients and dermis(10.5 %). Deposition of FN was found at the dermo-epidermal junction(52%), papillary dermis(57.9%) and dermal blood vessels(52.6%). 2. In the involved skin of 19 psoriatics before treatment, deposition of IgG was observed in the horny layer in 84.2% of the patients, upper epidermis(15.8%) and depositicin of FG was present in the horny layer(52.6%), upper epidermi(63.1%), dermo-epidermal junction(15.8%), upper dermis(15.8%) and dermal blood vessels(5.3%). Leposition of FN was found in the horny ayer(26.3%), upper epidermis (36.8%), dermo-epidermal junction(78.9%), upper dermis(89.5%) and ermal blood vessels(68.4%). 3. In the involved skin of 12 psoriatics after treatment, IgG was wealily deposited in the horny layer in 16.7% of the patients and deposition of FG was observed in the horny layer(8.3%), upper epidermis (16.7%), dermo-epidermal junction(8.3%) and dermis(8.3%). Deposition of FN was found in the upper epiderrnis(8.3%), dermo-epiderrnal junction(58.3%), dermis(66.%) and dermal blood vessels (33.3%) 4. In the normal skin of 8 control subjects, no deposition of IgG and, FG was observed while deposition of FN was found at the inummo-epidermal junction in 37.5% of the persons, upper dermis(25%) and dermal blood vessels(12.5%)
Antibodies ; Blood Vessels ; Epidermis ; Fibrinogen ; Fibronectins* ; Fluorescent Antibody Technique, Direct ; Humans ; Immunoglobulin G ; Immunoglobulins ; Keratinocytes ; Psoriasis ; Skin

In the present study, tap water iontophoresis as a method of treatment of palmoplantar hyperhidrosis was evaluated. Eighteen patients, twelve males and six females, with singnificant palmoplantar hyperhidrosis were treated on every weekday for 2 weeks. The hand and foot of the same side were randomly selected for the treatment by tap water iontophoresis according to the the method described by Levit. The selected hand and foot were immersed in a pair of pans containing tap water and exposed to 30V and 3 to 14mA of direct current for 20 minutes. The results obtained were as follows . Among 18 patients treated, 14(77.8%) accomplishei3 sufficient control of hyperhidrosis after 6 12(average 9.1) treatments. Two patients showed a moderate response and one weak response. One patient showed no response. Several patients experienced untoward effects such as mild itching, erythema, tingling sensation, exfoliation, compensatory hyperhidrosis, but the discomfort was not so severe as to stop the treatment
Erythema ; Female ; Foot ; Hand ; Humans ; Hyperhidrosis* ; Iontophoresis* ; Male ; Pruritus ; Sensation ; Water

Changes of histopathological findings with time were studied after scratching the skin of 37 patients with dermographism. Biopsies were also done in 13 normal healthy controls for comparison with unstroked skin of the patients. 1. Biopsies of unscratched skin of the patients showed no histologic difference from those of the skin from controls. 2. Neutrophils increased in number with time after scratching and maximum neutrophil count (mean 16.08+/-24.17/HPF) was observed at 90 minutes after scratching 3. Eosinophilic infiltration was also similar to that of neutrophils. Maximum eosinophil count (mean 324+/-4.76/HPF) was found at 60 minutes after scratching. 4. L ymphohistiocytic infiltration showed a similar tendency to that of neutrophils, but the degree of change was not so prorninent. 5. Before scratching, mast cell count in patients with dermographism showed no difference in number when compared with norrnal controls. In patients with dermographism, mast; cell count inclined to decrease after scratching. 6. Edema and lymphatic dilatation in the upper dermis were most prominent at 5 minutes after scratching and disappeared slowly thereafter.
Biopsy ; Cell Count ; Dermis ; Dilatation ; Edema ; Eosinophils ; Humans ; Mast Cells ; Neutrophils ; Skin

No abstract available.

A 33 years old house wife with accessory breast tissue is described and the literature is reviewed. The patient developed soft tumors in both axillae with axillary hair loss during the 8 th month of her 8 th pregnancy. This disorder is rather common in the literature but has been paied little attention dermatology.
Adult ; Axilla ; Breast* ; Dermatology ; Hair ; Humans ; Pregnancy ; Spouses

Polyethylene glycol (PEG)-3350 is the most frequently used lavage solution for bowel cleansing prior to colonoscopy or elective surgery because its large molecular weight means that it is poorly absorbed. However, if it leaks into the peritoneal cavity, complications may arise. Few published studies have assessed the absorption, distribution, metabolism and excretion of PEG. Moreover, no published clinical data regarding complications due to the intra-peritoneal leakage of PEG-3350 could be found. We report on an elderly patient who developed the poisoning caused by leaking of PEG-3350 during bowel preparation. It resulted in severe metabolic acidosis, hypernatremia, hyperosmolality and a high anion gap, but it was effectively treated with early continuous renal replacement therapy after surgery.
Absorption ; Acid-Base Equilibrium ; Acidosis ; Aged* ; Colonoscopy ; Humans ; Hypernatremia ; Metabolism ; Molecular Weight ; Peritoneal Cavity ; Poisoning* ; Polyethylene Glycols* ; Renal Replacement Therapy ; Therapeutic Irrigation

In cholangiographic techniques, the close relationship between choledochal cyst and anomalous union of pancreaticobiliary duct has attracted medical attention. There have been rare cases in which the papilla of Vater was found in a position other than its normal position, and such cases have been reported sporadically. However, such cases are interesting in the anatomical context. In this review, we present our experience of choledochal cyst in a 30-month-old boy in whom the papilla of Vater was positioned in the third portion of the duodenum.
Cholangiography ; Choledochal Cyst ; Duodenum ; Preschool Child

Traumatic epidermoid cysts are rare tumors occuring almost exclusively on the palms, palmar aspects of fingers, and soles. These cysts are thought to originate from a bit of epidermis implanted into the dermis after a penetrating or blunt wound. We report a case of typical traumatic epidermoid cyst on the sole of the right foot of a 23-year-old male student. The lesion was a coin-sized, tender, fluctuating cystic mass occuring 3 years after a penetrating wound by an iron nail. Histopathlogical examination revealed a deep dermal cyst lined by a thick, flattened, keratinizing wall with partial disruption accompanied by foreign-body reaction.
Dermis ; Epidermal Cyst* ; Epidermis ; Fingers ; Foot ; Foreign-Body Reaction ; Humans ; Iron ; Male ; Wounds and Injuries ; Wounds, Penetrating ; Young Adult

A 42-year old man was admitted for treatment of a fracture of the medial condyle of the left femur. After 10 days of cast immbilization of the above mentioned extremity, erythematous papulo-vesicular eruption was noted under the external splintage. We concluded that this was an unusual allergic contact dermatitis which is caused by CaSO4.1/2H20, and proved it by patch test in our clinic.
Calcium Sulfate ; Dermatitis, Allergic Contact ; Extremities ; Femur ; Patch Tests

Cavernous hemangioma is the most common primary tumor occurred in adults' orbit. This tumor has symptoms characteristically developing over several years with slowly progressive proptosis, eyeball deviation, hyperopia, diplopia and optic nerve compression. It's removal, necessary when there is progressive exophthalmos and visual deficit, is best performed en bloc to avoid intraoperative vleeding, the risk of residue, and potential further growth. In principle, surgical approach to the orbit must provide maximum safety and optimal visualization. The noncompressibility of the globe imposes greater demand on the need for some removal of the osseous orbit for surgical approach. This also must permit immediate functional and aesthetic reconstruction. The authors have experienced a case of large cavernous hemangioma in the orbit inferomedially. The surgical treatment of tumor was achieved by inferomedial approach combined with inferolateral orbitotomy. This surgical approach allows better visualization of the tumor and greater protection of essential anatomic structures. This also permits immediate functional and aesthetic reconstruction. So we present our case with a brief review of the literature related to orbital cavernous hemangioma.
Diplopia ; Exophthalmos ; Hemangioma, Cavernous* ; Hyperopia ; Optic Nerve ; Orbit*