1.Gall bladder wal varices:Easy diagnosis with multiphase incremental bolus dynamic CT.
Journal of the Korean Radiological Society 1993;29(6):1229-1233
Gall bladder wall varices are unusual manifestations of protal hypertention. Authors report 4 cases of gall bladder wall varices which were easily detected in IV bolus CT. All of our cases showed main portal vein obstruction but preserved intrahepatic portal flows with development of cavernous transformation. We could easily identify tortous and tubular structures with strong contrast enhancement in the gall bladder wall, compatible with gall bladder wall varices, at the early phase of IV bolus CT. Comparing with Doppler sonography, IV bolus CT is an easy and useful method for detection of gall bladder wall varices even in case of no prior information for portal vein abnormality.
Diagnosis*
;
Methods
;
Portal Vein
;
Urinary Bladder*
;
Varicose Veins
2.Patterns of Recurrence after Curative Resection of Hepatocellular Carcinoma: Radiological Type.
Jae Chun CHANG ; Jae Kyo LEE ; Jin Wook LEE
Journal of the Korean Radiological Society 1995;33(1):79-85
PURPOSE: To obtain the useful information about tumor behavior of hepatocellular carcinoma by analyzing the recurrence pattern after curative resection. MATERIALS AND METHODS: Forty-two patients who underwent curative resection of hepatocellular carcinoma were analyzed. Based on the firstly detected radiologic recurrence, we classified recurrence patterns into three types, type I;marginal recurrence, type II;intrahepatic nodular(multiple, single) and type III;extrahepatic. We also analyzed its duration of recurrence after curative resection. RESULTS: Eighteen patients showed no radiologic recurrence during follow-up period(mean 19.2 months). Twenty-four patients showed radiologic recurrence at 29 sites and its mean duration was 11.0 months. Recurrence patterns were seven cases in type I, 14 cases in type II(multiple 11, single three), eight cases in type III including two omental, two extrahepatic lymph node, two brain, one spine, and one intracranial metastasis. Among the extrahepatic recurrences, five cases showed only distant metastasis without hepatic recurrence. Mean duration of recurrence according to the site was 16.0 months in type I, 12.6 months in type II, 12.3 months in type III. Among 20 patients with single site recurrence, type 11(9.0 months) was earlier than type 1(10.3 months). CONCLUSION: lntrahepatic recurrence is more common than extrahepatic recurrence. Intrahepatic nodular, especially multinodular recurrence, is more common than marginal recurrence. Intrahepatic recurrence has tendency to develope earlier metastain earlier than marginal recurrence.
Brain
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Carcinoma, Hepatocellular*
;
Follow-Up Studies
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Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Recurrence*
;
Spine
3.Long term results and clinical evaluation of lung cancer.
Jae Hyun CHANG ; Jae Ho CHO ; Jin Woo CHANG ; Won Young SONG ; Byung Ha YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):463-469
No abstract available.
Lung Neoplasms*
;
Lung*
4.Clinical evaluation of 32 cases aortocoronary bypass with saphenous vein.
Jae Hyun CHANG ; Jin Woo CHANG ; Jae Ho CHO ; Won Young SONG ; Byung Ha YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):452-456
No abstract available.
Coronary Artery Bypass*
;
Saphenous Vein*
5.Surgical treatment of pulmonary aspergillosis.
Jae Ho JO ; Jin Woo CHANG ; jae Hyun CHANG ; Won Young SONG ; Byung Ha YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(5):380-383
No abstract available.
Pulmonary Aspergillosis*
6.A case of Behcet's syndrome.
Ju Hwa JIN ; Gong Chang HAN ; Jae Hoon CHUNG
Korean Journal of Obstetrics and Gynecology 1991;34(4):603-606
No abstract available.
Behcet Syndrome*
7.Castleman Disease Arising from IVlesentery: A Case Report.
Jae Chun CHANG ; Dong Sug KIM ; Hwa Jin LEE
Journal of the Korean Radiological Society 1995;32(5):775-778
Castleman disease is a benign disorder, usually occurring within mediastinum, characterized by proliferation of lymphold tissue. The authors report a rare case of Castleman disease originating from mesenteric root. The tumor was highly vascular, proved by dynamic CT examination and splanchnic angiography.
Angiography
;
Giant Lymph Node Hyperplasia*
;
Mediastinum
8.Restoration of Hormone Dependency in Estrogen Receptor - Lipofected MDA-MB-231 Human Breast Cancer Cells.
Young Jin SUH ; Jae Hee CHANG ; Chung Soo CHUN
Journal of the Korean Cancer Association 1999;31(3):473-482
PURPOSE: The loss of estrogen and progesterone receptors appeats to be associated with a progression to less differentiated and hormone-independent tumors. The gain of hormone independency over time even in estrogen receptor-positive tumors has become another obstacle to endocrine therapy for breast cancer. We tried to regain the hormone dependency in estrogen receptor-negative breast cancer cells by lipofecting estmgen receptor cDNA. MATERIALS AND METHODS: The mutant human estrogen receptor cDNA (pSGS-HEO) was lipofected into estrogen receptor-negative human breast cancer cell line MDA-MB-231, in an attempt to restore their sensitivity to antiestrogen. Then the effects of 17p-estradiol and tamoxifen were studied by counting viable cell numbers after treating the lipofected cell line with either one or together. RESULTS: Culture medium cantaining phenol red, a weak estrogen, has growth advantages compared with culture medium without it. In both culture conditions, cell growth was most profoundly inhibited in 4 days after lipofection with mutant human estrogen receptor cDNA, which was overcome after that day. Tamoxifen, as an antiestrogen, showed a growth inhibitory effect slightly stronger tban combined conditions of tamoxifen and 17- estradiol compared to estrogen-treated group and to control, and the inhibitory effect was lasted 4 days. CONCLUSION: The temporary induction of estrogen receptor by lipofection with pSGS-HEO on estrogen receptor-negative human breast cancer cell line MDA-MB-231 showed negative growth control on these cells by tamoxifen, indicating that liposome-mediated estrogen receptor transfection may be used as a novel therapeutic strategy for hormane independent human breast cancers in the near future.
Breast Neoplasms*
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Breast*
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Cell Count
;
Cell Line
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DNA, Complementary
;
Estradiol
;
Estrogen Receptor Modulators
;
Estrogens*
;
Genetic Therapy
;
Humans*
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Phenolsulfonphthalein
;
Receptors, Progesterone
;
Tamoxifen
;
Transfection
9.Metastatic Omental Hepatocellular Carcinoma: Two Cases Report.
Jae Chun CHANG ; Won Kyu PARK ; Mi Jin KIM
Journal of the Korean Radiological Society 1995;33(3):403-406
We report metastatic omental hepatocellular carcinoma in two patients with post-lobectomy hepatocellular carcinoma who have had previous abdominal surgery or the rupture of hepatocellular carcinoma. Ometal metastatic masses were similar to primary masses of the liver in pathologic findings as well as in radiologic findings.
Carcinoma, Hepatocellular*
;
Humans
;
Liver
;
Rupture
10.A comparative trial of Nalador and mechanical stimulation(Metreurynter) in the termination of midtrimester pregnancy.
Jung Ja JIN ; Eun Ju CHANG ; Jae Seok LEE ; Keon JIN ; Dong Jin KIM
Korean Journal of Obstetrics and Gynecology 1992;35(5):682-693
No abstract available.
Female
;
Humans
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Pregnancy*