1.Hybrid Treatment of Coexisting Renal Artery Aneurysm and Abdominal Aortic Aneurysm in a Gallbladder Cancer Patient.
Vascular Specialist International 2014;30(2):68-71
Renal artery aneurysm (RAA) is uncommon, and the coexistence of an abdominal aortic aneurysm (AAA) is an extremely rare condition with potentially high life-threatening mortality in case of rupture. Aneurysms can be treated by endovascular intervention or open surgery. Although most of aneurysms are treated by endovascular intervention, open surgery is often necessary for RAAs associated with the proximal renal bifurcation or the branches in the distal renal arteries. We report a rare case of coexisting RAA with AAA treated by hybrid method, consisting of endovascular aneurysm repair for AAA and open surgery for RAA located adjacent to the distal branches of the renal artery.
Aneurysm*
;
Aortic Aneurysm, Abdominal*
;
Gallbladder Neoplasms*
;
Humans
;
Mortality
;
Renal Artery*
;
Rupture
2.Conservative surgery and radiation therapy in the treatment of stage I and II breast cancer.
Journal of the Korean Cancer Association 1992;24(1):125-129
No abstract available.
Breast Neoplasms*
;
Breast*
3.Combination of Surgical Thrombectomy and Direct Thrombolysis in Acute Abdomen with Portal and Superior Mesenteric Vein Thrombosis.
Vascular Specialist International 2014;30(4):155-158
Portal vein (PV) thrombosis (PVT) is a rare condition with development of thrombosis in the PV and its branches. Further extension to the splenic and superior mesenteric vein (SMV) causes intestinal infarction, with a reported mortality of up to 50%. A variety of treatments for PVT exist including anticoagulation, thrombolysis, surgical thrombectomy, insertion of shunts, bypass surgery, and liver transplantation. We experienced a case of successfully treated by surgical thrombectomy with direct thrombolysis into the thrombosed-PV and SMV. A 31-year-old male presented worsening abdominal pain for one week. Preoperative contrast enhanced computed tomography scan revealed complete PVT extending to splenic vein and SMV. The PV was accessed surgically and opened by thrombectomy; visual inspection confirmed proximal and distal flow. Urokinase was administered directly into the inferior mesenteric vein with successful decrease in thrombus burden. The complete angiography showed complete dissolution of thrombosis in PV and SMV.
Abdomen, Acute*
;
Abdominal Pain
;
Adult
;
Angiography
;
Humans
;
Infarction
;
Liver Transplantation
;
Male
;
Mesenteric Veins*
;
Mortality
;
Portal Vein
;
Splenic Vein
;
Thrombectomy*
;
Thrombosis*
;
Urokinase-Type Plasminogen Activator
;
Venous Thrombosis
4.Neuroendocrine immunoperoxidase markers to predict chemotherapy response in lung cancer patients.
Hyuk JUNG ; Sang Jae LEE ; Un Sub PARK
Journal of the Korean Cancer Association 1993;25(5):664-672
No abstract available.
Drug Therapy*
;
Humans
;
Lung Neoplasms*
;
Lung*
5.A study of artifacts in MR imaging induced by metalic aneurysm clips.
Joo Hyuk LEE ; Kee Hyun CHANG ; Jae Hyung PARK
Journal of the Korean Radiological Society 1992;28(2):307-313
To investigate MR artifacts induced by metallic implants, scans were obtained using both the ferromagnetic Drake lip and the non ferromagnetic Yasargil clip. Scan were taken through the area of clips using geometrical phantom. The MRI was performed by spin echo technique and gradient echo technique on both 2.0T and 0.5T MR unit. The luthors evaluated the nature and differences of artifacts in each sequence and parameter. Artifacts induced by both lips were noted in the direction of frequency encoding gradient, and consisted of region of signal loss abutted in one side by survilinear region of bright signal. Geometric distortion of image was marked in the Drake clip, out was minimal in the Yasargil clip under both 2.0T and 0.5T. Artifacts were more pronounced in the gradient echo technique than those of the spin echo technique on both 2.0T and 0.5T. Although there were no differences n the nature of artifacts induced by the Drake clip among each parameter in the spin echo technique under 2.0T, artifacts were slightly more pronounced on T2 weighted image under the 0.5T field, but no differences were found in the nature of artifacts induced by the Yasargil clip in the spin echo technique under, both the 2.0T and 0.5T fields. Marked artifacts were induced through the small area of the Drake clip which were included in the scan plane, but induced artifacts were small when a small area of the Yasargil clip was included in the scan plane. It seemed likely hat artifacts were slightly more pronounced in the 2.0T than the 0.5T field in both clips, but objective evaluation of the difference was difficult, In conclusion, these results can be an essential basis for the interpretation of MR images or patents with metallic inplants.
Aneurysm*
;
Artifacts*
;
Lip
;
Magnetic Resonance Imaging*
;
Magnets
6.An experimental study on enhanced antitumor effect of cyclophosphamide by methylxanthines human gastric cancer cells(NUGC-4).
Jae Jun KIM ; Min Hyuk LEE ; Kyung Bal HUR
Journal of the Korean Cancer Association 1992;24(4):469-479
No abstract available.
Cyclophosphamide*
;
Humans*
;
Stomach Neoplasms*
7.Malignant Granular Cell Tumor of the Shoulder: A case report.
Jae Hun CHUNG ; Jae Hyuk LEE ; Jong Hee NAM ; Chan CHOI ; Min Cheol LEE
Korean Journal of Pathology 2000;34(6):475-479
A malignant granular cell tumor (MGCT) occurred in the left shoulder of a 62-year-old man. The patient underwent wide marginal excision followed by chemotherapy and radiotherapy. A metastatic tumor was identified in the axillary lymph node 22 months after the excision of the shoulder mass. The primary tumor was a poorly circumscribed mass measuring 5 5 4 cm. On cut section, it was a solid mass with yellowish tan color. Histologically, both primary and metastatic tumor consisted of polygonal cells with abundant granular cytoplasm and a vesicular nucleus with a prominent nucleolus. Two to three mitotic figures per ten high power fields at 200 were counted. Tumor cells were weakly stained with periodic acid-Schiff (PAS) preparation both before and after diastase digestion, and were positive for S-100 protein, neuron-specific enolase (NSE), and vimentin. By electron microscopy, the cytoplasm was filled with numerous autophagolysosomes containing myelin figures, mitochondria, and fragmented rough endoplasmic reticula. Basal laminae and angulated bodies were also noted. These findings suggest schwannian differentiation of this tumor.
Amylases
;
Basement Membrane
;
Cytoplasm
;
Digestion
;
Drug Therapy
;
Granular Cell Tumor*
;
Humans
;
Immunohistochemistry
;
Lymph Nodes
;
Microscopy, Electron
;
Middle Aged
;
Mitochondria
;
Myelin Sheath
;
Phosphopyruvate Hydratase
;
Radiotherapy
;
S100 Proteins
;
Shoulder*
;
Triacetoneamine-N-Oxyl
;
Vimentin
8.Erratum: Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest.
Kyoung Jeen MIN ; Jin Joo KIM ; In Cheol HWANG ; Jae Hyuk WOO ; Yong Su LIM ; Hyuk Jun YANG ; Keun LEE
Korean Journal of Critical Care Medicine 2017;32(1):88-88
The author's affiliation should be corrected. We apologize for any inconvenience that may have caused.
9.Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest.
Kyoung Jeen MIN ; Jin Joo KIM ; In Cheol HWANG ; Jae Hyuk WOO ; Yong Su LIM ; Hyuk Jun YANG ; Keun LEE
Korean Journal of Critical Care Medicine 2016;31(4):342-350
BACKGROUND: The aim of this study was to investigate the relationships between left ventricular ejection fraction (LVEF) and mortality and neurologic outcomes with post-cardiac arrest syndrome (PCAS) after out-of-hospital cardiac arrest (OHCA). METHODS: Patients with PCAS after OHCA admitted to the intensive care unit between January 2014 and December 2015 were analyzed retrospectively. RESULTS: total of 104 patients were enrolled in this study. The mean age was 54.4 ± 15.3 years, and 75 of the patients were male (72.1%). Arrest with a cardiac origin was found in 55 (52.9%). LVEF < 45%, 45-55%, and > 55% was measured in 39 (37.5%), 18 (17.3%), and 47 (45.2%) of patients, respectively. In multivariate analysis, severe LV dysfunction (LVEF < 45%) was significantly related to 7-day mortality (odds ratio 3.02, 95% Confidence Interval 1.01-9.0, p-value 0.047). CONCLUSIONS: In this study, moderate to severe LVEF within 48 hours after return of spontaneous circulation was significantly related to 7-day short-term mortality in patients with PCAS after OHCA. Clinicians should actively treat myocardial dysfunction, and further studies are needed.
Echocardiography
;
Humans
;
Intensive Care Units
;
Male
;
Mortality*
;
Multivariate Analysis
;
Out-of-Hospital Cardiac Arrest*
;
Passive Cutaneous Anaphylaxis
;
Retrospective Studies
;
Stroke Volume*
10.A Comparative Study of Immunohistochemistry and PCR-SSCP for Detection of p53 Mutation In Gastric Carcinoma.
Jong Soon KIM ; Jae Hyuk LEE ; Min Cheol LEE ; Chang Soo PARK ; Sang Woo JUHUNG
Korean Journal of Pathology 1998;32(1):21-28
Mutation of the p53 tumor-suppressor gene in exons 4 through 9 was examined in 34 cases of primary advanced gastric cancer using PCR-SSCP (polymerase chain reaction-single strand conformation polymorphism) and the results were compared with p53 protein expression as determined by immunohistochemistry (IHC) using a monoclonal antibody(DO-1). p53 protein detected by IHC was observed in 14 cases (41.2%) and genotypic mutation detected by PCR-SSCP in exons 4-9 was observed in 13 cases (38.2%) One case showed an aberrant band on PCR-SSCP both in Exon 7 and Exon 8/9. p53 alteration detected by either IHC or PCR-SSCP was observed in 19 cases (55.9%), but only 8 cases (23.5%) showed both p53 mutation and protein expression. We also tried to obtain the correlation between relative intensity of the shifted bands on PCR-SSCP and percentage of positive cells by IHC, but a significant correlation was not seen between relative intensity of shifted bands on PCR-SSCP and positve cell ratio. A discrepancy between p53 protein expression and p53 mutation is observed in primary gastric carcinomas. The reason for this discrepancy are not apparent. However, examination of gastric carcinomas for mutations in other exons may identify a better correlation with protein overexpression. The results obtained in this study suggest that the negative reaction for p53 immunohistochemistry may not necessarily mean no genetic alteration of the p53 locus.
Exons
;
Immunohistochemistry*
;
Stomach Neoplasms