The Diego blood group system consists of two pairs of antigens, Dia and Dib The incidence of Dia is low among pure Caucasian, Blacks, Polynesian and Eskimo, however, the rnongolians and American indians have both Dia and Dib. We report a case of two days old male who was admitted on first day of life for jaundice and subsquently exchange transfusion was performed on second day of life for bilirubin of 20 mg/dl. The blood groups of patient and his mother were both Rh D positive 0 type. Direct and indirect Coombstest were strong positive in the patient and indirect Coombstest was positive in his mother. We found anti-Dib antibody in his rnother's serum. The phenotype of Diego blood group system of the patient and his mother were Di (a+b+) and Di (a+b- ), respectively and hemolytic anemia in this case was due to anti-Dib antibody.
African Continental Ancestry Group ; Anemia, Hemolytic ; Bilirubin ; Blood Group Antigens ; Humans ; Incidence ; Indians, North American ; Inuits ; Jaundice ; Male ; Mothers ; Phenotype

BACKGROUND/AIMS: Helicobacter pylori is found in more than 90% of patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Regression of lymphoma after H. pylori eradication was reported. Therefore, early detection of gastric MALT lymphoma is important. On reported several endoscopic findings, nonspecific gastritis with erosion and ulceration were common and there is no typical endoscopic findings. METHODS: Therefore we analyzed the endoscopic findings of 16 low-grade B-cell gastric MALT lymphoma confirmed by biopsy, PCR and immunostain and compared histologic change after eradicating H. pylori infection in patients who refused operation retrospectively from March 1995 to October 1996. RESULTS: The male: female ratio was 7:9 and mean age was 43,7 years ald (23-71 yr), On endoscopic findings of gastric MALT lymphoma, irregular shaped geographic superficial ulcer was 7 cases (43.7%), diffuse mucosal nodularity was 4 cases (25.0%) and erosion was 3 cases (18.7%). The most common site of MALT lymphoma was antrum and angle. H. pylori was positive in 87.5% (14/16 cases) and eradication of H. pylori was done in patients who refused operation and histologic improvement after H. pylori eradication was found in 62.5% (5/8 cases). CONCLUSIONS: The most common endoscopic findings of gastric MALT lymphoma was irregular geographic superficial ulcer but diffuse mucosal nodularity and erosions were also common. Therefore, biopsy must be taken, especially on the antrum and angle although nonspecific lesion may be suspected.
B-Lymphocytes ; Biopsy ; Endoscopy ; Esophagus* ; Female ; Gastric Mucosa* ; Gastritis ; Helicobacter pylori ; Humans ; Intestines* ; Lymphoid Tissue* ; Lymphoma* ; Lymphoma, B-Cell, Marginal Zone ; Male ; Polymerase Chain Reaction ; Retrospective Studies ; Stomach* ; Ulcer

Subacute necrotizing lymphadenitis was first reported by Kikuchi and Fujimoto in 1972. Young females no more than 30 years of age are mainly affected. It usually manifests as fever and cervical lymphadenopathy. We experienced three cases of subacute necrotizing lymphadenitis in an 11-year-old boy, a 12- year-old boy and an 11-year-old girl. Symptoms presented were URI signs, diarrhea, headache and weight loss along with fever and cervical lymphadenopathy. Fever persisted from 9 to 30 days and did not respond to antibiotics. We performed aspiration biopsy of cervical lymph node which was consistent with subacute necrotizing lymphadenitis in all cases. We used oral steroid in one case. Fever and lymphadenopathy subsided spontaneously within one month. There were no other complications.
Anti-Bacterial Agents ; Biopsy, Needle ; Child ; Diarrhea ; Female ; Fever ; Headache ; Humans ; Lymph Nodes ; Lymphadenitis* ; Lymphatic Diseases ; Male ; Weight Loss

Subacute necrotizing lymphadenitis was first reported by Kikuchi and Fujimoto in 1972. Young females no more than 30 years of age are mainly affected. It usually manifests as fever and cervical lymphadenopathy. We experienced three cases of subacute necrotizing lymphadenitis in an 11-year-old boy, a 12- year-old boy and an 11-year-old girl. Symptoms presented were URI signs, diarrhea, headache and weight loss along with fever and cervical lymphadenopathy. Fever persisted from 9 to 30 days and did not respond to antibiotics. We performed aspiration biopsy of cervical lymph node which was consistent with subacute necrotizing lymphadenitis in all cases. We used oral steroid in one case. Fever and lymphadenopathy subsided spontaneously within one month. There were no other complications.
Anti-Bacterial Agents ; Biopsy, Needle ; Child ; Diarrhea ; Female ; Fever ; Headache ; Humans ; Lymph Nodes ; Lymphadenitis* ; Lymphatic Diseases ; Male ; Weight Loss

Spontaneous intestinal perforation is characterized by isolated mucosal ulceration with acute inflammation, submucosal edema and serosal inflammation, and considered as a separate clinical entity from necrotizing enterocolitis. The causes of spontaneous intestinal perforation are administration of indomethacin, dexamethasone, umbilical artery catheterization, defect of intestinal musculature, and systemic candidasis. Intestinal perforation caused by defects of intestinal musculature is rare, and its pathogenesis remains uncertain. The authors report one case of a premature infant with defect in intestinal musculature confirmed through postoperation biopsy who was misdiagnosed as intestinal perforation due to necrotizing enterocolitis.
Biopsy ; Catheterization ; Catheters ; Dexamethasone ; Edema ; Enterocolitis, Necrotizing ; Humans ; Indomethacin ; Infant, Newborn ; Infant, Premature ; Inflammation ; Intestinal Perforation* ; Ulcer ; Umbilical Arteries

The carcinoid tumors of middle ear are very rare, however, more than 50 cases including 2 cases in Korea have been reported since 1980. A 36-year-old male had been managed under the diagnostic impression of hemotympanum due to head trauma in 2005; he revisited our clinic after 8 years with sudden facial paralysis and external auditory canal mass. Canal wall down mastoidectomy and tympanoplasty were performed and pathologic results revealed a carcinoid tumor of the middle ear. A facial paralysis of this patient was cured after the treatment.
Adult ; Carcinoid Tumor* ; Craniocerebral Trauma ; Ear Canal ; Ear, Middle* ; Facial Paralysis* ; Humans ; Korea ; Male ; Tympanoplasty

On July 2009, 5 fly larvae were discovered inside the nose of a 76-year-old female. She was living in Cheonan-si, and in a state of coma due to rupture of an aortic aneurysm. Surgery was performed on the day of admission, and the larvae were found 4 days later. By observing their posterior spiracle, the larvae were identified as Lucilia sericata. Considering the rapid development of this species, the infection was likely acquired during hospitalization. Further investigation on the hospital environment should be needed to know the origin of the infection.
Aged ; Animals ; Aortic Rupture/complications ; Cross Infection/diagnosis/parasitology ; *Diptera ; Female ; Humans ; Korea ; *Larva ; Myiasis/*diagnosis/*parasitology ; Nose Diseases/*diagnosis/*parasitology

Inflammatory fibroid polyp(IFP) typically prescnts as a polypoid mass in the gastric antrum. Radiologically and endoscopically, it can be confused with polypoid carcinoma or submucosal stromal tumor. The histogenetic origin of IFP has been controversial, but it is considered as a reactive lesion of the myofibroblastic nature. IFP is rarely concomitant with gastritis cystica profunda(GCP) which is also one of the nonneoplastic inflammatory polyps. We report a case of IFP associated with GCP presenting as a large polypoid mass in the previously unoperated stomach of a 78-year-old woman. The mass was mainly located in the submucosa of the antrum and the cut surface exhibited a myxoid and glistening appearance with partial cystic change. Histologically, the mass showed marked proliferation of spindle cells, small blood vessels and many inflammatory cells, especially eosinophils. Also, there were many variable sized glands composed of gastric foveolar epithelia within the mass. In conclusion, the rarity of these two associated lesions in the present case may cause difficulty in diagnosis, and therefore recognition about these lesions is needed. In addition, this case supports the nature of IFP as being reactive rather than neoplastic.
Aged ; Blood Vessels ; Diagnosis ; Eosinophils ; Female ; Gastritis* ; Humans ; Leiomyoma* ; Myofibroblasts ; Polyps* ; Pyloric Antrum ; Stomach*

BACKGROUND: The Hematopathology Study Group of the Korean Society of Pathologists conducted a nation-wide retrospective analysis of Korean pediatric lymphoma, to provide pathologic data on pediatric/adolescent lymphoma subtypes and features. METHODS: All lymphoma cases of all age groups were collected during a recent 2 year-period (2005-2006) from 32 institutes in Korea. Among 3,686 lymphoma patients, 142 who were age 18 or less were classified according to the World Health Organization (WHO) classification. RESULTS: Among 142 pediatric/adolescent lymphoma patients, Hodgkin lymphoma accounted for 21 (14.8%) and non-Hodgkin lymphoma (NHL) for 121 (85.2%). Hodgkin lymphoma appears to be more common in the pediatric/adolescent age group than in the all-ages group (14.8% vs 4.4%). T- and natural killer cell-NHL was more common in the pediatric/adolescent age group than in the all ages group (46.3% vs 22%). The majority of Korean pediatric/adolescent NHL cases was composed of Burkitt lymphoma, T- or B-lymphoblastic lymphoma, anaplastic large-cell lymphoma, and diffuse large B-cell lymphoma. For lymphoma patients under the age of 6 years, most had B-lymphoblastic or Burkitt lymphoma, which commonly presented at extranodal sites. CONCLUSIONS: The distribution of lymphoma subtypes in the pediatric/adolescent age group is quite different from the distribution of adults, but it was quite similar to distribution in Western countries.
Academies and Institutes ; Adult ; Burkitt Lymphoma ; Hodgkin Disease ; Humans ; Incidence ; Korea ; Lymphoma ; Lymphoma, B-Cell ; Lymphoma, Large-Cell, Anaplastic ; Lymphoma, Non-Hodgkin ; Retrospective Studies ; World Health Organization

BACKGROUND: The aim of study was to determine the relative frequency of malignant lymphoma according to World Health Organization (WHO) classification in Korea. METHODS: A total of 3,998 cases diagnosed at 31 institutes between 2005 and 2006 were enrolled. Information including age, gender, pathologic diagnosis, site of involvement and immunophenotypes were obtained. RESULTS: The relative frequency of non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) was 95.4% and 4.6%, respectively. B-cell lymphomas accounted for 77.6% of all NHL, while T/natural killer (T/NK)-cell lymphomas accounted for 22.4%. The most frequent subtypes of NHL were diffuse large B-cell lymphoma (42.7%), extranodal marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (19.0%), NK/T-cell lymphoma (6.3%) and peripheral T-cell lymphoma (PTCL), unspecified (6.3%), in decreasing order. The relative frequency of HL was nodular sclerosis (47.4%), mixed cellularity (30.6%), and nodular lymphocyte predominant (12.1%) subtypes. Compared with a previous study in 1998, increase in gastric MZBCL and nodular sclerosis HL, and slight decrease of follicular lymphoma, PTCL, and NK/T-cell lymphoma were observed. CONCLUSIONS: Korea had lower rates of HL and follicular lymphoma, and higher rates of extranodal NHL, extranodal MZBCL, and NK/T-cell lymphoma of nasal type compared with Western countries. Changes in the relative frequency of lymphoma subtypes are likely ascribed to refined diagnostic criteria and a change in national health care policy.
Academies and Institutes ; Delivery of Health Care ; Hodgkin Disease ; Korea ; Lymphocytes ; Lymphoid Tissue ; Lymphoma ; Lymphoma, B-Cell ; Lymphoma, B-Cell, Marginal Zone ; Lymphoma, Follicular ; Lymphoma, Non-Hodgkin ; Lymphoma, T-Cell, Peripheral ; Sclerosis ; World Health Organization