Verrucous carcinoma is a rare variant of squamous cell carcinoma that is more often seen in the oral cavity and larynx, but extremely rare in the paranasal sinus. In establishing the diagnosis, close cooperation is required between the clinician and pathologist, since the lesion appears obviously malignant on clinical examination but on pathologic study it may be reported as hyperplastic or papillomatous or as hyperkeratotic benign squamous epithelium. Verrucous carcinoma should be treated by surgical excision because there is evidence to suggest that the lesion may become more aggressive after radiotherapy and surgery gives better survival rates than radiotherapy. We experienced a case in which the patient presented with a history of right nasal obstruction and intermittent facial pain for about 4 months and was ultimately diagnosed as having verrucous carcinoma of maxillary sinus. Caldwell-Luc's operation was performed. We report this case with a review of the literature.
Carcinoma, Squamous Cell ; Carcinoma, Verrucous* ; Diagnosis ; Epithelium ; Facial Pain ; Humans ; Larynx ; Maxillary Sinus* ; Mouth ; Nasal Obstruction ; Radiotherapy ; Survival Rate