BACKGROUND: Gonorrhea is one of the most common venereal diseases in the world. Antibioticresistance development has been an issue with the penicillinase-producing Neisseria gonorrhoeae(PPNG) development. It is possible for PPNG to be resistant to other medications. Therefore, it is significant to determine its frequency rate and its disposition. OBJECTIVES: In this surveillance, we examined overall development frequency of PPNG from 1981 ti 1998. Comparing current five years' frequency rate with that of previous five year, we predicted possible development rate and described the procedures the physicians must take into account in gonorrhea treatment. METHODS: We examined the development frequency of PPNG in male patients of the venereal disease clinic of Jung-gu Community Health Center in Seoul from 1981 to 1998. Also, we analyzed the overall tendency with time series analysis using statistics package, SPSS 7.5.Grouping the years in five-year units, development frequency of PPNG of current five years (1994-1998) was compared with that of previous years. RESULTS: For the result of monthly analysis of frequency rate of PPNG development from 1981 to 1998, the rate tendency came out with a sligh rise (slope : 0.15). And for the result of comparison of grouped years, in current five years, its rate was 51.6%, marking a significant decline from that of the previous five years, which was 57.2% (p-value : <0.0001). CONCLUSION: The rate of current five years was reported to have declined from the previous years. However, the rate is still over 50%. Therefore, the government should continue the PPNG surveillance with test of sensitivity of the medications in use. Moreover, to eliminate gonorrhea, the education on high risk groups should continue and physicians should use a dose of adequate antibiotics in treatment.
Anti-Bacterial Agents ; Community Health Centers* ; Education ; Gonorrhea ; Humans ; Male ; Neisseria gonorrhoeae* ; Neisseria* ; Seoul* ; Sexually Transmitted Diseases

A kidney containing more than 1,000 cc fluid in its collecting system is generally defined as giant hydronephrosis. A case of a 24 years old Korean male soldier having giant hydronephrosis (1,800 cc) associated with uretero-pelvic junction stricture and multiple renal stones is presented with review of literatures.
Constriction, Pathologic ; Humans ; Hydronephrosis* ; Kidney ; Male ; Military Personnel ; Young Adult

Authore examined for the width, the trabecular pigment band and the iris process of the chamber angle in the non-glaucomatous eyes of the Korean people (total 86 eyes, among (them male 58 eyes, female 28 eyes, and ages of 7-67) by using the 3 mirror contact lens and slit-lamp (Goldmann 900). And these findings were evaluated with the age and the sex distribution. Also these preliminary data are now assisting in the study of pathologic findings of the chamber angle.
Female ; Humans ; Iris ; Male ; Sex Distribution

Authors experienced five different cases of keratitis such as metaherpetic keratitis, bullous keratitis, chemical keratitis and superficial punctate keratitis have been markedly improved by subconjunctival injection of Tathion (30-50mg), a glutathion prepartion. All cases showed remarkable improvement with better visual acuity following the treatment. Especially it was another choice of treatment in persisting case of metaherpetic keratitis with parenchymal infiltration. No side effects have been observed during this procedure.
Keratitis* ; Visual Acuity

Ketalar, a new parenteral anesthetic, was used as a clinical trial for 14 surgical cases ranged from 2 to 15 year old children, and also intraocular pressures of their patient's sound eyes were measured before and after Ketalar injection, I.M. 5-10 mg/kg. Unlike conventional anesthetic agents, Ketalar caused a significant rise in intraocular pressure within 5 minutes and then the pressure improved to normal range about 15 minutes after Ketalar injection. Ketalar could not recommended as a general anethetic agent in case who should examine the intraocular pressure. In eye surgery under 15 year old children, this agent would be a safe and effective general anesthetic, and in an emergent eye injured case, Ketalar is an agent of first choice and can injects to patient regardless of diet intake.
Adolescent ; Anesthetics ; Child* ; Diet ; Humans ; Intraocular Pressure* ; Ketamine* ; Reference Values

In search of the effect of air pollution on the eye, the authors examined ocular symptoms and diseases in both an urban(Seoul) and two rural populations (Suwon and Changsung). The Prevalence rate of ocular symptoms and diseases between 109 occupational drivers of more than 3 years career in Seoul area which is one of the air polluted urban areas and 150 populations in the two different rural areas as a control group were compared. The prevalence rate of ocular symptoms was 89% in Seoul, 10% in Suwon and 23% in Changsung area, and those of ocular diseases were 35%, 6% and 10% in the same areas, respectively. The prevalence rate of ocular symptoms and diseases is respectively 3 to 4 times more prevalent in occupational drivers than in the control groups. Many other etiologic factors such as occupation, labor condition, environmental stress or different way of living may influence the prevalence rate between the two groups, however, it would be presumed that the main causative factor to cause ocular symptoms and diseases is probably due to air pollution.
Air Pollution ; Gyeonggi-do ; Occupations ; Prevalence* ; Rural Population* ; Seoul

The permeability in vitro of rabbit corneal epithelium alone and whole cornea to four radioactive substances of various molecular weights-tritiated water (THO: molecular weight 22), mannitol (molecular weight 182), inulin(molecular weight 5,175), and dextran(molecular weight 77,500)-was directly measured by using a newly designed lucite chamber (Fig.1) and a proportional counter system for radioisotope experiments. The permeability of the corneal epithelium and the whole cornea varied with the size of molecular weight (Fig.4) and curvilineally with respect to molecular radius (Fig.5). Certainly the data (Table 2 and 3) support that the greater part of non-electrolyte permeation was through intercellular spaces passively. The epithelial or whole corneal permeability fell markedly as the molecular weight increased from 22 to 5,175. Above the molecular size of inulin, the permeability decreased much as the molecular weight increased. Generally, tritiated water permeability was about 150 times greater than that of mannitol and about 2,000 times than that of inulin and about 10,000 times than that of dextran. The difference between the permeability of the epithelium alone and that of the whole cornea was not noticed. Futhermore, the permeability, either of epithelium alone or the whole cornea, did not vary significantly depending upon the location of the hot side with any of the four kinds of isotope-labelled solutes, whether it was set at the epithelial or endothelial side of the corneal membrane (P>0.1). These results may support that the epithelial layer plays a main role as a physical barrier for nonelectrolyte solutes movement across the rabbit cornea.
Cornea* ; Dextrans ; Epithelium ; Epithelium, Corneal* ; Extracellular Space ; Inulin ; Mannitol ; Membranes ; Molecular Weight ; Permeability* ; Polymethyl Methacrylate ; Radius ; Water

A total of 75 subjects were examined using Hahn's color vision test and Hahn's Double 15-Hue test. Among the 75 subjects, 62 subjects detected by screening test among 2700 high school students had defective color vision but good visual acuity and no retinal diseases. The other 13 subjects were detected in out-patient ophthalmic clinic. Results of examination in classifying the types and estimating the extent of color defects were obtained. 1. In the total 75 persons examined, extent of the color defects were as follows; mild ............ 6 cases, moderate.........31 cases, strong...........38 cases. 2. The classification of types of congenital color defects were as follows; Protan .........2 cases, Deutan ........25 cases, Unclassified...48 cases. Lack of advanced study on color discrimination for congenital color deficiency resulted in existing job discrimination against a color defective person by restricting his/her job opportunity. Therefore this kind of research has very important meanings and should be continued.
Classification ; Color Vision ; Discrimination (Psychology)* ; Humans ; Mass Screening ; Outpatients ; Retinal Diseases ; Visual Acuity

Two cases of typical granular corneal dystrophy, a girl of 22 years old and her younger brother of 18 years old, were observed clinically. Considerably active reaction of the pilocarpine test was observed on the case and the result was evaluated. References which cover various aspects of the corneal dystrophy were reviewed.
Adolescent ; Female ; Humans ; Pilocarpine ; Siblings ; Young Adult

No abstract available.
Helicobacter pylori* ; Helicobacter* ; Urease*