1.Pre-and Postoperative Evaluation of Patent Ductus Arteriosus in Children.
In Hee PARK ; Jung Hee LEE ; In Joon SEOL ; Heung Jae LEE
Journal of the Korean Pediatric Society 1985;28(7):683-694
No abstract available.
Child*
;
Ductus Arteriosus, Patent*
;
Humans
2.A Clinical and Laboratory Study on Infection in Childhood Leukemia.
Jung Hee LEE ; Kwang Hyun KIM ; In Joon SEOL ; Heung Jae LEE ; Hahng LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1986;29(7):1-11
No abstract available.
Leukemia*
3.Four Cases of Gastric Hamartomatous Polyps without Polyposis Coli.
Jung Myung CHUNG ; Sang Hyuk LEE ; Youn Jae LEE ; Joon Yong JEONG ; Sang Young SEOL ; Hye Kyoung YOON ; Hee Geun HA ; Hee Seung WHANG
Korean Journal of Gastrointestinal Endoscopy 1996;16(6):994-999
Hamartoma is a very rare congenital tumor. A few cases of hamartomatous pol yps in the stomach were reported. Most of harrurtomatous polyps in the stomach occur in patients of polyposis coli. We have experienced four cases of gastric hamartomatous polyps without polyposis coli. There are some differences between previously reported cases and ours. In our casee, the distribution of age is from fourth to ninth decade, men and women ratio is 1: 1. The number of polyps are one in three cases and two in one case. The size of polyps is from 5mm to 12 mm. The location of polyps are various, but most common in antrum. We have experienced four cases which were different from previously reported ones and report them with a brief review of literatures.
Adenomatous Polyposis Coli*
;
Female
;
Hamartoma
;
Humans
;
Male
;
Polyps*
;
Stomach
4.Four Cases of Gastric Hamartomatous Polyps without Polyposis Coli.
Jung Myung CHUNG ; Sang Hyuk LEE ; Youn Jae LEE ; Joon Yong JEONG ; Sang Young SEOL ; Hye Kyoung YOON ; Hee Geun HA ; Hee Seung WHANG
Korean Journal of Gastrointestinal Endoscopy 1996;16(6):994-999
Hamartoma is a very rare congenital tumor. A few cases of hamartomatous pol yps in the stomach were reported. Most of harrurtomatous polyps in the stomach occur in patients of polyposis coli. We have experienced four cases of gastric hamartomatous polyps without polyposis coli. There are some differences between previously reported cases and ours. In our casee, the distribution of age is from fourth to ninth decade, men and women ratio is 1: 1. The number of polyps are one in three cases and two in one case. The size of polyps is from 5mm to 12 mm. The location of polyps are various, but most common in antrum. We have experienced four cases which were different from previously reported ones and report them with a brief review of literatures.
Adenomatous Polyposis Coli*
;
Female
;
Hamartoma
;
Humans
;
Male
;
Polyps*
;
Stomach
5.Intracranial Hypertension Following Epidural Blood Patch in a Patient With Spontaneous Intracranial Hypotension.
Seol Hee BAEK ; Yeon Sun WOO ; Jin Woo PARK ; Jae Gyum KIM ; Kyung Hee CHO
Journal of the Korean Neurological Association 2014;32(1):30-33
Epidural blood patch (EBP) is one of the treatments for spontaneous intracranial hypotension (SIH), and its complications have rarely been reported. We report a patient with SIH and developed intracranial hypertension after EBP. The mechanism of rebound intracranial hypertension was uncertain. If the patient presented with a different type of headache or newly developed neurological symptoms after treatment of SIH, rebound intracranial hypertension should be considered and the proper treatment needed quickly.
Blood Patch, Epidural*
;
Headache
;
Humans
;
Intracranial Hypertension*
;
Intracranial Hypotension*
6.Mature Cystic Teratoma.
Sung Yeun YANG ; Jae Whan KIM ; Su Kyoung KWON ; Tae Hee KIM ; Sang Hoon SEOL
Korean Journal of Medicine 2007;72(6):696-697
No abstract available.
Mediastinal Neoplasms
;
Teratoma*
7.Definition of the peptide mimotope of cellular receptor for hepatitis C virus E2 protein using random peptide library.
In Hee LEE ; Jae Eun PAIK ; Sang Yong SEOL ; Dae Hyun SEOG ; Sae Gwang PARK ; In Hak CHOI
Immune Network 2001;1(1):77-86
BACKGROUND: Hepatitis C virus(HCV), a family of Flaviviridae, has a host cell-derived envelope containing a positive-stranded RNA genome, and has been known as the maj or etiological agent for chronic hepatitis, hepatic cirrhosis, and hepatocellular carcinoma. There remains a need to dissect a molecular mechanism of pathogenesis for the development of therapeutic and effective preventive measure for HCV. Identification of cellular receptor is of central importance not only to understand the viral pathogenesis, but also to exploit strategies for prevention of HCV. This study was aimed at identifying peptide mimotopes inhibiting the binding of E2 protein of HCV to MOLT-4 cell . METHODS: In this study, phage peptide library displaying a random peptides consisting of 7 or 12 random peptides was employed in order to pan against E2 protein. Free HCV particles were separated from the immune complex forms by immunoprecipitation using anti-human IgG antibody, and used for HCV-capture ELISA. To identify the peptides inhibiting E2-binding to MOLT-4 cells, E2 protein was subj ect to bind to MOLT-4 cells under the competition with phage peptides. RESULTS: Several phage peptides were selected for their specific binding to E2 protein, which showed the conserved sequence of SHFWRAP from 3 different peptide sequences. They were also able to recognize the HCV particles in the sera of HCV patient s captured by monoclonal antibody against E2 protein. Two of them, showing peptide sequence of HLGPWMSHWFQR and WAPPLERSSLFY respectively, were revealed to inhibit the binding of E2 protein to MOLT-4 cell efficiently in dose dependent mode. However, few membrane-associated receptor candidates were seen using Fasta3 programe for homology search with these peptides. CONCLUSION: Phage peptides containing HLGPWMSHWFQR and WAPPLERSSLFY respectively, showed the inhibition of E2-binding to MOLT-4 cells. However, they did not reveal any homologues to cellular receptors from GenBank database. In further study, cellular receptor could be identified through the screening of cDNA library from MOLT-4 or hepatocytes using antibodies against these peptide mimotopes.
Antibodies
;
Antigen-Antibody Complex
;
Bacteriophages
;
Carcinoma, Hepatocellular
;
Conserved Sequence
;
Databases, Nucleic Acid
;
Enzyme-Linked Immunosorbent Assay
;
Flaviviridae
;
Gene Library
;
Genome
;
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
;
Hepatitis, Chronic
;
Hepatocytes
;
Humans
;
Immunoglobulin G
;
Immunoprecipitation
;
Liver Cirrhosis
;
Mass Screening
;
Peptide Library*
;
Peptides
;
RNA
8.Flash ERG changes in Parkinson's disease: With reference to medications and clinical forms.
Jae Moon KIM ; Seol Hee HAN ; Kwang Woo LEE ; Sang Bok LEE ; Ho Jin MYUNG
Journal of the Korean Neurological Association 1989;7(1):26-34
Authors have studied photopic and scotopic flash EPGs for 19 control subjects and 20 patients with Parkinson's disease before and after various anti-Parkinsonian therapy. The following fingings were observed 1. There was no significant difference in implicit time of photopic and scotopic a and b waves between the control and the Parkinsonian groups(P(t)>0.05). 2 Amplitudes of photopic and scotopic a and b-waves were smaller in Parkinsonian group during the pre-medication therapy than in control group(P(t)<0.05) however those of photopic a-and b- waves and scotopic b-wave were normalized with anti-Parkinsonian therapy(P(t)<0.01). 3 Parkinsonian patients treated with dopa preparations showed the significant increases of amplitde of scotopic b wave(P(t)<0.001) but those treated with anticholinergics, Amantadine or Bromocryptine did not(P(t1>0.05). 4. Compared with that of tremor predominant Parkinsonism the amplitudes of photopic and scotopic a-and b-waves were small in patients with akineto-rigidity(P(t)<0.01). Therefore it is concluded that the dopaminergic changes in retinal cells are responsible for producing b wave as well as a wave. So clinically flash EFGs can. Be used beneficially in treating Parkinsonian patients in view of choosing the anti-Parkinsonian drugs and monitoring the effectiveness of therapy.
Amantadine
;
Bromocriptine
;
Cholinergic Antagonists
;
Dihydroxyphenylalanine
;
Humans
;
Parkinson Disease*
;
Parkinsonian Disorders
;
Retinaldehyde
;
Tremor
9.Acute lymphoblastic leukemia initially presenting with polymyalgia rheumatica.
Jae Hee HWANG ; Ju Kyoung SONG ; In Seol YOO ; Seong Wook KANG
Korean Journal of Medicine 2009;76(Suppl 1):S234-S237
Polymyalgia rheumatica (PMR) is a clinical syndrome of unknown etiology characterized by aching and stiffness in the shoulder girdle, pelvic girdle, and neck that occurs in people over the age of 50 years. New-onset proximal muscle pain and stiffness in subjects older than 50 are the most common symptoms of PMR, but polymyalgic pain can also be present in patients with malignant neoplasms. The musculoskeletal system may be involved in malignancy either directly or indirectly, particularly in cases involving hematological malignancies. Only a few cases of cancer-associated PMR have been reported worldwide, and this is the first in Korea. We report the case of a 58-year-old man diagnosed with PMR associated with acute lymphoblastic leukemia.
Hematologic Neoplasms
;
Humans
;
Korea
;
Middle Aged
;
Muscles
;
Musculoskeletal System
;
Neck
;
Paraneoplastic Syndromes
;
Polymyalgia Rheumatica
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Shoulder
10.Stereotactic Vacuum-Assisted Biopsy of Microcalcifications Using an Upright Add-On Type Stereotactic Mammography Unit.
Sung Hun KIM ; Jae Hee LEE ; Byoung Joo SONG ; Sang Seol JUNG
Journal of the Korean Radiological Society 2007;57(3):291-297
PURPOSE: This study examined the yield of mammographically detected calcifications following a stereotactic vacuum-assisted biopsy (SVAB) using an upright add-on type stereotactic device. MATERIALS AND METHODS: Ninety-two women underwent a SVAB between April 2002 and December 2005, and 90 calcifications obtained by the SVAB were evaluated retrospectively. The calcification retrieval rate was examined. The false negative and underestimation rates were determined by comparing the biopsy results with the results from surgery and follow-up mammography. RESULTS: The calcification retrieval rate was 97.8% (90/92). The histopathology of the 90 lesions was benign for 66 (73.3%), borderline for 3 (3.3%) and malignant for 21 (23.3%). A total of 22 malignancies were confirmed surgically. SVAB had a false negative rate of 4.5 % (1/22). The underestimation rate of a surgically excised atypical ductal hyperplasia (ADH) and of ductal carcinoma in situ (DCIS) was 50% (1/2) and 10% (2/20), respectively. CONCLUSION: The use of SVAB with an upright add-on type stereotactic device is an efficient biopsy method for mammographically detected microcalcifications, with low false negative and high calcification retrieval rates.
Biopsy*
;
Biopsy, Needle
;
Breast Neoplasms
;
Calcification, Physiologic
;
Carcinoma, Intraductal, Noninfiltrating
;
Female
;
Follow-Up Studies
;
Humans
;
Hyperplasia
;
Mammography*
;
Retrospective Studies
;
Stereotaxic Techniques