1.Chronic obstructive pulmonary disease: association with gastroesophageal reflux disease.
Young Chul KIM ; Jae Hee OH ; Joo Nam BYUN
Journal of the Korean Radiological Society 1992;28(5):715-723
Multiple factors including gastroesophageal reflux disease (GERD) were evaluated for a case-control study in Chonnam area to investigate the causative entity of COPD. Data on the multiple causative factors from hospital records and interview survey were analyzed in three groups of COPD(64 cases as case group), normal lung (83 cases as control group 1) and non-COPD lung disease (45 cases as control group 2). Smoking status, history of adulthood pulmonary infection and frequent history of URI, socioeconomic status, and GERD were significantly different between COPD group and control group 1. Drinking status, physical height of the subjects and GERD were significantly different between COPD group and control group 2. If control group 1 was used, odds ratio of GERD and COPD was 5.68(95%confidence interval, 95% CI:2.59-12.45) and 4.81 (95% CI:1.89-10.53) when adjusted by age and smoking status. If control group 2 was used. Odds ratio of GERD and COPD was 4.22 (95% CI:1.69-10.56) and 4.59 (95% CI:1.64-12.86) when adjusted by alcohol and adulthood respiratory infection status. In summary, there results suggested that GERD might play a causative role in the development of COPD.
Case-Control Studies
;
Drinking
;
Gastroesophageal Reflux*
;
Hospital Records
;
Jeollanam-do
;
Lung
;
Lung Diseases
;
Odds Ratio
;
Pulmonary Disease, Chronic Obstructive*
;
Smoke
;
Smoking
;
Social Class
2.Serum Interleukin-10 Levels in Rheumatoid Arthritis Patients.
Bin YOO ; Jae Kyoung PARK ; Won Il OH ; Sun Whan OH ; Hee Bom MOON
The Journal of the Korean Rheumatism Association 1997;4(1):33-38
OBJECTIVE: To investigate whether the serum levels of IL-10 in patients with rheumatoid arthritis are different from those of normal controls and SLE patients and to find out any correlation with disease activity parameters of rheumatoid arthritis. METHODS: Sera from 20 healthy normal persons, 16 rheumatoid arthritis patients and 16 patients with systemic lupus erythematosus were collected and measured for IL-10 and IL-6. Various disease activity parameters were measured in RA patients. RESULTS: The serum level of IL-10 in RA patients was significantly elevated compared to normal controls but lower than those of SLE patients. In RA patients there was no definite correlation between the disease activity parameters and serum IL-10 levels. Despite significant improvements in terms of various disease activity parameters, there was no significant change of serum IL-10 levels after treatment in RA patients. In seropositive RA patients, positive correlation was found between serun IL-10 and rheumatoid factor levels. CONCLUSION: Our findings show that the serum IL-10 levels in patietns with RA are elevated compared to normal controls but lower than those of SLE patients. There was no correlation between serum IL-10 levels and disease acivity parameters of RA.
Arthritis, Rheumatoid*
;
Humans
;
Interleukin-10*
;
Interleukin-6
;
Lupus Erythematosus, Systemic
;
Rheumatoid Factor
3.A clinical study on varicella zoster virus infection and treatment in children with malignant lymphoproliferative disease.
Hak Won KIM ; Jae Won OH ; Sung Hee OH ; Ha Baik LEE ; Hahng LEE
Journal of the Korean Pediatric Society 1991;34(9):1246-1254
No abstract available.
Acyclovir
;
Chickenpox*
;
Child*
;
Herpesvirus 3, Human*
;
Humans
4.A study on current immunization status attending an above-middle from class primary school in Seoul.
Jae Won OH ; Sung Lae PARK ; Sung Hee OH ; Hahng LEE
Journal of the Korean Pediatric Society 1991;34(9):1187-1200
No abstract available.
Compliance
;
Humans
;
Immunization*
;
Seoul*
;
Vaccination
5.An epidemiologic study of measles among hospitalized pediatric patients.
Sung Lae PARK ; Jae Won OH ; Sung Hee OH ; Hahng LEE
Journal of the Korean Pediatric Society 1991;34(10):1356-1364
No abstract available.
Epidemiologic Studies*
;
Humans
;
Measles*
6.A Case of Pulmonary Lymphangiectasis Associated with Chylothorax.
Min Hee KIM ; Jae Kyoung LEE ; Oh Bae CHUN ; Byoung Hoon YOO ; Jae Hyung YOO
Journal of the Korean Pediatric Society 1987;30(4):422-426
No abstract available.
Chylothorax*
;
Lymphangiectasis*
7.Histopathologic Findings of Mastopathy in Diabetes Mellitus.
Jae Ho HAN ; Hee Jung KIM ; Woo Hee JUNG ; Ki Keun OH
Korean Journal of Pathology 1999;33(7):503-506
Diabetic mastopathy is a clinicopathologic entity which was first described as a dense fibrous breast mass in insulin-dependent diabetes mellitus. The purpose of this article was to document diabetic mastopathy histologically which had been diagnosed as fibrocystic disease and to avoid unnecessary surgical procedures in breast mass simulating malignancy in diabetic patients. We examined eight excisional breast biopsies from seven patients. Three diabetic patients with type I insulin-dependent diabetes mellitus presented with bilateral (2 patients) or unilateral (1 patient) rapidly growing palpable breast masses. Four patients with type II noninsulin-dependent diabetes mellitus presented with bilateral (2 patients) or unilateral breast mass (1 patient). One patient had no symptoms. All of them had late complications of diabetes mellitus such as nephropathy, neuropathy and retinopathy. Mammographic findings such as ill- defined mass density and asymmetric increased density suggested malignancy. However, all of them had been diagnosed as fibrocystic disease. On review, the most consistent pathologic finding was keloid-like stromal fibrosis. Others were ductitis or ductulitis, thickening of basement membrane of ducts or ductules, mononuclear perivasculitis and lobulitis. Six of eight breast satisfied all five criteria for diabetic mastopathy.
Basement Membrane
;
Biopsy
;
Breast
;
Diabetes Complications
;
Diabetes Mellitus*
;
Diabetes Mellitus, Type 1
;
Diabetes Mellitus, Type 2
;
Fibrosis
;
Humans
8.A Clinical - Pathological Study of Uterine Smooth Muscle Tumor of Uncertain Malignant Potential.
Hee Jong LEE ; Hee Sug RYU ; Young Han PARK ; Hee Jae JOO ; Seung Chun YANG ; Kie Suk OH
Korean Journal of Obstetrics and Gynecology 2000;43(10):1769-1774
No abstract available.
Muscle, Smooth*
;
Smooth Muscle Tumor*
9.A Follow-up Study of DMSA Renal Scan in Chidren with Acute Pyelonephritis and Vesicoureteral Reflux.
Pyung Kil KIM ; Jae Seung LEE ; Chang Hee OH ; Won Kyoo CHOI
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):145-151
Angiosarcomas are rare tumors, seen most commonly in the skin and soft tissue of head and neck region. But it has been described in numerous body sites including thyroid, breast, liver, spleen, bone, etc.. Their biological behaviors depend on the microscopic grade, site of origin, and multifocality. We report the unique cytological features of an angiosarcoma in pleural fluid. A 61-year-old woman presented with a 6 month history of dyspnea on exertion and chest pain. Chest computerized tomography(CT) revealed multiple subpleural small nodules in the right lung and widespread air space consolidation and pleural effusion in the left lung. CT of liver revealed multiple small low attenuated lesion. The smears obtained from pleural fluid showed hypocellularity with a hemorrhagic background. The tumor cells were highly pleomorphic oval or spindle in shape and presented singly, in loose groups, in knitted syncytial aggregates, and in acinar pattern. Their nuclei had vesicular chromatin with delineated, thick nuclear membranes and occasionally a large eosinophilic, prominent nucleolus. The cytoplasm was plump, thin or projected in spindly fashion. Almost all tumor cells showed variable sized intracytoplasmic vacuoles and their nuclei were sometimes crescentic by a huge vacuole. Occasional binucleated tumor cells and mitotic figures were present. Cellular debris and streaky materials were identified. Needle biopsy specimen from the pleura revealed anastomosing slit-like spaces lined by pleomorphic tumor cells. The tumor cells showed a strong reactivity for CD31 and vimentin and focal weak reactivity for factor VIII-related antigen.
Female
;
Humans
;
Follow-Up Studies
;
Biopsy
10.Neurilemmoma of the infratemporal fossa: report of a case.
Sun Youl RYU ; Hee Kyun OH ; Geon Jung KIM ; Jae Hyun YUN ; Hong Ran CHOI
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(4):81-87
No abstract available.
Neurilemmoma*