1.A Study on the Design of High-Frequency Jet Ventilator Using PLL system.
Yeungnam University Journal of Medicine 1989;6(2):63-70
This paper describes to design and to examine the mechanical characteristics of high frequency jet ventilator. The device consists of Phase lock loop (PLL) system, solenoid valve driving control part and Air regulating system. This study is carried out by changing several factors such as endotracheal tube (E.T. tube) diameter, injector cannula diameter, 1%, and frequency (breaths/min.) having direct effects on the gas exchange as well as parameters of the entrained gas by venturi effect, so as to measure the tidal volume and minute volume. This system characteristics were as follows: 1) Frequency: 6-594 bpm 2) Inspiration time: 1-99% 3) Variance of input air pressure: 1-30 PSI
Air Pressure
;
Catheters
;
Tidal Volume
;
Ventilators, Mechanical*
2.Expression of p53, c-myc, Transforming Growth Factor-alpha and -beta in Human Epithelial Ovarian Tumors.
Jae Hwa LEE ; Young Ok LEE ; Man Ha HUH
Korean Journal of Pathology 1996;30(1):23-31
The author examined expression of tumor-related antigens, such as p53 tumor supressor protein, c-myc, TGF-alpha, and TGF-beta proteins in 75 cases of surgically resected epithelial ovarian tumors. Peroxidase immunohistochemistry was used to determine the frequency of expression, the relationship among expression of these antigens and histopathological spectrums, and clinical stage, and their potential prognostic significance. The results are summarized as follows. A positive correlation was found between expression of p53(P=0.02), c-myc(P=0.03), and TGF-alpha(P=0.001) and histological degrees of malignancy(benign, borderline, or malignant) in epithelial ovarian tumors. A significant correlation was found between expression of p53 and histological degrees of malignancy in serous ovarian tumors(P=0.003) and mucinous tumors (P=0.049). A significant correlation was also found between expression of c-myc and the histological grade of serous carcinomas(P=0.02). A correlation between expression of these antigenic proteins and clinical stage of epithelial ovarian tumors was not demonstrated. Expression of p53 and c-myc was closely correlated with expression of TGF-alpha irrespective of the histological degrees of malignancy and type of epithelial ovarian tumors(0.4 < or = K < or = 0.7). The results of this study support the ideas that expression of c-myc and TGF-alpha might be a useful prognostic indicator in human ovarian carcinomas, and expression of p53 could be another indicator of prognosis, as the expression of p53 is characteristic in that the expression is mostly seen in invasive ovarian carcinomas.
Humans
3.Intrageneric Relationships of Trichoderma Based on Internal Transcribed Spacers and 5.8S rDNA Nucleotide Sequences.
Gi Young KIM ; Goang Jae LEE ; Myung Gyu HA ; Tae Ho LEE ; Jae Dong LEE
Mycobiology 2000;28(1):11-16
The nucleotide sequences of the internal transcribed spacer (ITS) regions of the ribosomal DNA including the 5.8S ribosomal RNA gene (rDNA) have been determined for 11 species in order to analyze their intrageneric relationships. The total length of these sequences ranged from 530 nucleotides for Trichoderma reesei KCTC 1286 to 553 nucleotide for Trichoderma koningii IAM 12534. Generally speaking, the length of ITS1 region was about 30 nucleotides longer than that of the ITS2 region. Also, the sequences of 5.8S rDNA were more conserved in length and variation than those of ITS regions. Although the variable ITS sequences were often ambiguously aligned, the conserved sites were also found. Thus, a neighbor-joining tree was constructed using the full sequence data of the ITS regions and the 5.8S rDNA. The Trichoderma genus used to be grouped on the basis of the morphological features and especially the shape of phialides needs to be reexamined. The phylogenetic tree displayed the presence of monophylogeny in the species of Trichoderma. Therefore, it was difficult to distinguish the intrageneric relationships in the Trichoderma genus.
Base Sequence*
;
DNA, Ribosomal*
;
Nucleotides
;
Phylogeny
;
RNA, Ribosomal, 5.8S
;
Trichoderma*
4.A clinical study of the effect of early (<12 months) versus late (12-24 months) onset in infantile asthma.
Jae Won OH ; Ji Yeon LIM ; Ha Baik LEE
Journal of the Korean Pediatric Society 1992;35(2):201-210
No abstract available.
Asthma*
5.Effects of Capsaicin Pretreatment on the Functions of Mouse Peritoneal Macrophages.
Jae Seung PARK ; Jeong Ho LEE ; Tai You HA
Korean Journal of Immunology 2000;22(1):39-49
No abstract available.
Animals
;
Capsaicin*
;
Macrophages, Peritoneal*
;
Mice*
6.A Case of solar Urticaria.
No Jae PARK ; Won Woo LEE ; Duck Ha KIM
Korean Journal of Dermatology 1990;28(3):341-344
A 23-year-old woman had solar urticaria that was activated by visible light and UVA, but the intensity of the urticarial reaction of visible light was more pronounced than that of UVA. The results of passive and reverse passive transfer studies were negative, We report a case of solar urticaria which is characterized by overlapping features of 60th type Il and Il[ in the classification of Harber.
Classification
;
Female
;
Humans
;
Light
;
Urticaria*
;
Young Adult
7.Modulatory effect of water and/or food deprivation, and cyclophosphamide administration on immune response in mice.
Tai You HA ; Won Jae SONG ; Jeong Ho LEE
Korean Journal of Immunology 1992;14(1):53-62
No abstract available.
Animals
;
Cyclophosphamide*
;
Food Deprivation*
;
Mice*
8.Modulatory effect of water and/or food deprivation, and cyclophosphamide administration on immune response in mice.
Tai You HA ; Won Jae SONG ; Jeong Ho LEE
Korean Journal of Immunology 1992;14(1):53-62
No abstract available.
Animals
;
Cyclophosphamide*
;
Food Deprivation*
;
Mice*
10.Comparison of two in vitro assays for serum house dust mite - specific IgE with skin testiong in allergic subjects.
Jae Won OH ; Ha Baik LEE ; Jee Young JUNG
Journal of Asthma, Allergy and Clinical Immunology 1999;19(4):535-541
BACKGROUND: The skin prick test and in vitro allergen-specific IgE assays are commonly used to diagnose atopic diseases. However, there is still a need for comparison of their diagnostic efficiency. Objective and METHOD: To evaluate their clinical efficiency, the results of UniCAP and multiple antigen simultaneous test (MAST) were compared with skin prick test results. After 51 allergic patients completed skin prick test (SPT), serum sample was collected and UniCAP and MAST were performed to determine specific IgE to house dust mite (Dermatophagoides pteronyssinus : Dp and D. farinae. Df). Result : When SPT was used as a reference standard, UniCAP depicted higher sensitivity of 88.8% to Dp IgE and 91.4% to Df - IgE, but lower specificity of 73.3% to Dp IgE and 75.0% to Df - IgE. However, MAST had lower sensitivity of 75.1% to Dp-IgE and 71.4% to Df - IgE, higher specificity of 93.3% to Dp-IgE and 93.7% to Df - IgE. The values of UniCAP and MAST were significantly correlated with the reactivity grade of skin prick test, respectively. Additionally, the response of SPT was not apparently associated with ECP levels. CONCLUSION: These study results may suggest that both UniCAP and MAST are generally feasible for measuring house dust mite - specific IgE and that they are both replicable.
Dust*
;
Humans
;
Immunoglobulin E*
;
Pyroglyphidae*
;
Sensitivity and Specificity
;
Skin*