Restoration of the M-P joint of a damaged or lost joint by trauma, tumor and others is necessary for adequate function of the hand. Several procedure have been described for restoration of the M-P joint. We experienced a case of vascularized joint transter for a lost joint by trauma. After 1 year and 2 months follow-up, there have been no degenerative change and no pain.
Follow-Up Studies ; Hand ; Joints

BACKGROUND: Direct wet mount examination of vaginal secretion, widely applied for the diagnosis of Trichomonas vaginalis infection in woman patients, is rapid and economical. However, the sensitivity of this technique is not so high. In this study enzyme-linked immunosorbent assay(ELISA) was employed for the detection of serum anti-T. vaginalis IgG antibodies from vaginal trichomoniasis patients. METHODS: Eighty sera from trichomonoasis patients who visited a Dr. Yoon Kyong's Obstetric & Gynecologic Clinic in Songnam and 30 non-infected healthy men were tested for detection of anti-T. vaginalis IgG antibody. Soluble lysate and excretory-secretory antigen prepared by mixing of six isolates of T. vaginalis, and lysate from one isolate(KT4) were used as antigen for ELISA. RESULTS: The sensitivity of ELISA using lysate of six isolates was 95.0%, and the sensitivity of the lysate from KT4 and mixed excretory-secretory antigen from 6 isolates were 86.4% and 76.3%, respectively. Specificities of ELISA by three 93.3%, 96.3% and 92.0%, respectively. CONCLUSION: It is suggested that ELISA using mixed lysate of T. vaginalis six isolates could be useful tools for the diagnosis of trichomoniasis.
Antibodies ; Diagnosis ; Enzyme-Linked Immunosorbent Assay ; Female ; Gyeonggi-do ; Humans ; Immunoglobulin G* ; Male ; Trichomonas vaginalis ; Trichomonas*

No abstract available.

Melkersson-Rosenthal (M-R) syndrome consists of a triad of (1) recurrent peripheral facial nerve paralysis which develops alternatively on both sides of face, (2) non-inflammatory facial edema, and (3) furrowed tongue. Since the cause of M-R syndrome is unknown, various forms of therapy have been tried, but there were no conclusive evidence that they altered the course of the disease. A 27-year-old female and a 44-year-old male patient with recurrent facial nerve paralysis were diagnosed with M-R syndrome. We report the two cases of M-R syndrome with the brief review of literatures.
Adult ; Edema ; Facial Nerve ; Female ; Humans ; Male ; Melkersson-Rosenthal Syndrome* ; Paralysis ; Tongue, Fissured

OBJECTIVES: To investigate the pattern of subclinical hypothyroidism (SCH) in patients with bipolar disorders managed by lithium or valproic acid. METHODS: The study participants were 106 patients with DSM-IV bipolar disorders receiving planned maintenance treatment at the Mood Disorders Clinic of Seoul National University Bundang Hospital (aged between 17 and 64, mean duration of follow-up = 875.65 days). Using the bipolar disorder registry, thyroid function data were analyzed to assess the frequency of and the risk factors for SCH in patients managed by lithium (n = 64) or valproic acid (n = 42) for more than 5 months. RESULTS: Overall frequencies of SCH were 20.3% (13/64) in the lithium group, 14.3% (6/42) in the valproic acid group, and between the two groups there is no difference (p = 0.43). No differences were observed in the potential risk factors for SCH between the two groups including age, sex, subtype of bipolar disorder, baseline TSH, and concomitant antipsychotic use. In cases with SCH, thyroid-stimulating hormone (TSH) showed a tendency to increase at 3 month after the initiation of lithium or valproic acid. A gradual increase in the number of patients showing SCH was found within the first 3 years of medication. CONCLUSIONS: With regular monitoring and careful assessment, there was no difference in the risk of SCH between lithium and valproic acid maintenance. The risk of mood stabilizer-associated SCH may gradually increase within 3 years following the commencement of medication, thereby mandating close monitoring for the first 3 years of treatment. Further studies with large sample size would be needed to confirm these findings.
Bipolar Disorder* ; Diagnostic and Statistical Manual of Mental Disorders ; Follow-Up Studies ; Humans ; Hypothyroidism* ; Lithium* ; Mood Disorders ; Risk Factors ; Sample Size ; Seoul ; Thyroid Gland ; Thyrotropin ; Valproic Acid*

The Muenke syndrome (MS) is characterized by unicoronal or bicoronal craniosynostosis, midfacial hypoplasia, ocular hypertelorism, and a variety of minor abnormalities associated with a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. The birth prevalence is approximately one in 10,000 live births, accounting for 8-10% of patients with coronal synostosis. Although MS is a relatively common diagnosis in patients with craniosynostosis syndromes, with autosomal dominant inheritance, there has been no report of MS, in an affected Korean family with typical cephalo-facial morphology that has been confirmed by molecular studies. Here, we report a familial case of MS in a female patient with a Pro250Arg mutation in exon 7 (IgII-IGIII linker domain) of the FGFR3 gene. This patient had mild midfacial hypoplasia, hypertelorism, downslanting palpebral fissures, a beak shaped nose, plagio-brachycephaly, and mild neurodevelopmental delay. The same mutation was confirmed in the patient's mother, two of the mother's sisters and the maternal grandfather. The severity of the cephalo-facial anomalies was variable among these family members.
Adult ; Asian Continental Ancestry Group/*genetics ; Child, Preschool ; Craniosynostoses/*genetics/surgery ; DNA Mutational Analysis ; Female ; Humans ; Hypertelorism/genetics ; Korea ; Male ; *Mutation ; Pedigree ; Phenotype ; Receptor, Fibroblast Growth Factor, Type 3/*genetics ; Skull/*abnormalities/surgery ; Syndrome ; Treatment Outcome

The incidence of fetal cardiac arrhythmia is approximately 1-3%. Sustatined fetal tachyarrhythmia may cause fetal hydrops and rnay lead to fetal death. We experienced a case of fetal atrial flutter without fetal hydrops at 34 weeks of gestation, which was diagnosed by fetal echocardiography. Transplacental fetal therapy with maternal digoxin administration resulted in restoration of normal fetal sinus rhythm. At birth, the infant showed normal electrocardiographic finding with normal Apgar scores.
Arrhythmias, Cardiac ; Atrial Flutter* ; Digoxin ; Echocardiography ; Electrocardiography ; Fetal Death ; Fetal Therapies ; Humans ; Hydrops Fetalis ; Incidence ; Infant ; Mothers* ; Parturition ; Pregnancy ; Tachycardia

PURPOSE: The superior orbital fissure syndrome is a complex of impaired function of the cranial nerves that enter the orbit through this fissure. It is a very rare disease which is characterized by ophthalomoplegia, ptosis and proptosis of the eye, reflex dilation of the pupil, and anesthesia of the upper eyelid and forehead. This syndrome may be the result of craniofacial bone fractures as well as neoplasm of the retrobulbar space, hematomas in the orbital muscle cone and retrobulbar space, and hematoma and infection of the cavernous sinus. In this case, 12 year-old boy was stung at his medial side of the right upper eyelid by fishing-rod. This patient is described with features of a superior orbital fissure syndrome. Superior orbital fissure syndrome is a very rare disease. We report a case of superior orbital fissure syndrome. METHODS: Ptosis and complete external ophthalmoplegia were found in that eye. Snellen acuity of the right eye was 20/20. Dilation of the right pupil with loss of sensation on the right upper side of eyelid and forehead was noted. Under the impression of superior orbital fissure syndrome, systemic steroid was administered orally. RESULTS: A month after trauma, the patinet had no limit of motion at extraocular muscle except upward gaze and improved ptosis. Three months after the trauma, the patient had no signs and symptoms except sluggish pupillary reflex on the right eye.
Anesthesia ; Cavernous Sinus ; Child ; Cranial Nerves ; Exophthalmos ; Eyelids ; Forehead ; Fractures, Bone ; Hematoma ; Humans ; Male ; Ophthalmoplegia ; Orbit* ; Pupil ; Rare Diseases ; Reflex ; Reflex, Pupillary ; Sensation

BACKGROUND: A large number of children with psychosocial dysfunction are not recognized within schools or primary care settings. In several research, an increasing amount of attention has been paid to the importance of low family support as a predictor of psychosocial dysfunction in children. Our study examined the agreement and relationship between the lack of family support as measured by the Family APGAR and child psychosocial dysfunction as screened by the Pediatric Symptom Checklist(PSC). Therefore, We studied the usefulness of Family APGAR as a screening tool of child psychosocial dysfunction. METHODS: We set 643 children that are engaged in elementary school. We gave a questionnaire to their parents and made them record the questionnaire which contained the sociodemographic data, past history of child and parents, the Family APGAR and the translated Pediatric Symptom Checklist(PSC). Finally, we analysed only 506 complete data. We use the SAS/PC 6.12 that is a statistical analysis program. RESULTS: Children with a lack of family support(APGAR) were 5.1 times as likely to receive scores indicating dysfunction on the PSC(PSC). Families with a lack of support were significantly more likely to report low parental educational achievement and low income. Sixty percent of children from families with a lack of support were identified as having a psychosocial dysfunction by the PSC rating; however, only 24% percent of the children identified with psychosocial dysfunction by the PSC had scores indicating poor family functioning on the Family APGAR. Families with a lack of support had significantly higher total scores on PSC(mean=20.2) than families with adequate support(mean=11.9). The strength of the agreement between the Family APGAR and the PSC was k=.29. CONCLUSION: A lack of family support is associated with child psychosocial dysfunction as assessed by the PSC. However, the Family APGAR was not a sensitive measure of child psychosocial dysfunction, and thus it supplements, but does not replace the PSC.
Child* ; Educational Status ; Humans ; Mass Screening ; Parents ; Primary Health Care ; Surveys and Questionnaires

Authors repGrted one case of malignant melanoma which is located in the conjunctiva of the left eye This male patient, aged 45, has been a history of progressive enlargement of this melanoma since over ten years. At the time of first visit to the hospital, this melanoma revealed dark brownish strawbery-like pedunclated mass in his medial bulbar conjunctiva, and extended to fornix, palpebral conjunctiva, and lidmargin. Subtotal exenteration, BCG therapy, and X-ray radiation was performed successfully and was conformed histopathologically. In addition to some clinical observation, a brief review of literature has been described.
Conjunctiva* ; Humans ; Male ; Melanoma* ; Mycobacterium bovis