No abstract available.
Asian Continental Ancestry Group* ; Humans ; Korea* ; Orthodontics*

The tibial pilon fracture has been described as difficult fracture to manage. We have reviewed 23 cases of tibial pilon fractures from Mar. 1987 to Feb. 1993 at our hospital. 1. The fractures were classified into five types according to the system of Ovadia and Beals and the methods of treatment were divided into two groups; 9 cases were treated with Ilizarov device(Group I). 6 cases out of Group I were type 3, 4 and 5. Other methods were performed in 14 cases(Group II). 8 cases out of Group II were type 3, 4, and 5. 2. In type 3, 4 and 5 fractures, there were 86 per cent good and fair radiographic results in Group I and 63 per cent good and fair results in Group II. 3. Satisfactory results were obtained by the treatment of Ilizarov method especially in type 3, 4 and 5 fractures. The advantages of Ilizarov device were its primary reduction with ligamentotaxis, easy open reduction due to proximal and distal stabilization, minimal soft tissue injury and minimal internal fixation.
Ilizarov Technique ; Soft Tissue Injuries

Spinal stenosis is defined as diminition in the size of the spinal canal that produces nerve entrapment resulting in symptoms, the most common of which is low back pain & radiating pain to leg. The central spinal canal contains the dura and other meninges, and inside these, the nerves of the cauda equina. The nerve root canal contains the spinal nerve from the point which the dura leaves the intervertebral foramina. Each foramen is a door through which the nerve enters to the nerve root canal. In its canal the nerve passes behind the disc and then in front of the superior articular process of the lower vertebra. Pathological and anatomical changes by various cases can produce narrowing of the central and nerve root canal. But they are sometimes not important because they are not severe enough to cause nerve entrapment and such medical treatment, Spinal stenosis is only significant when nerves are entraped, indicated by severe leg pain and sometime by sensory and motor changes. Spinal stenosis is classified into two groups: congenital and acquired. Among acquired groups, the combined type is most common and significant. Authors have experienced 61 cases of spinal stenosis and among these, 58 cases were treated surgically between 1981 and 1984 at the Department of Orthopaedic Surgery, Eulji Glneral Hospital, Daejeon. The following results were obtained. 1. There were 52 males and 33 females, and peak incidence in 5th and 6th decade(69%) 2. The most common type by Arnoldi's etiological classification was combined type(69%) 3. The most common chief complaint on admission was low back pain and radiating pain to leg (43%) 4. The most common sign was limitation of lumbar hyperextension (75.9%) and S.L.R.test was positive in only 12 cases(20.7%). 5. The common findings of myelography were hour glss appearance (39.7%) and complete block (27.6%), and simple radiologic findings were hypertrophy of facet joint, osteophyte formation in the periphery of vertebral bodies involved and narrowing of disc speace. 6. The A-P diameter of spinal canal was between 14.44 mm and 14.97 mm in simple findings, and the A-P diameter of dural sac between 8.10 mm and 9.19 mm in myelography. The spinal index was between 1:4.90 and 1:5.60. 7. Decompressive surgery was done in the 2 levels in 39 cases (67.3%), 3 levels in 10 cases (17.2%) and 1 level in 9 cases (15.5%). Discectomy was done in 40 cases (69%) and partial laminectomy was done in 58 cases (100%). 8. The most common site was L3,4-L4,5 (36.2%).
Cauda Equina ; Classification ; Dental Pulp Cavity ; Diskectomy ; Female ; Humans ; Hypertrophy ; Incidence ; Laminectomy ; Leg ; Low Back Pain ; Male ; Meninges ; Myelography ; Nerve Compression Syndromes ; Osteophyte ; Spinal Canal ; Spinal Nerves ; Spinal Stenosis ; Spine ; Zygapophyseal Joint

No abstract available.
Malocclusion*

The author compared and analysed the roentgenocephalograms of one hundred Korean adults with the normal occlusion (50 males and 50 females), which were taken on the centric occlusion and the rest position of the mandible respectively for every subject, and then researched the relations among the relaxed muscle of the mandible, lightly touched of the lips, and the position just after the swallowing of saliva, of which 38 among 50 males had the rest position of the mandible. The results are as followings: 1. The anterior facial height increases more at the rest position of the mandible than at the centric occlusion, while the posterior facial height decreases. 2. The mandible moves more backward and downward at the rest position of the mandible than at the centric occlusion. 3. The facial procumbency and the incisor tooth inclination increases more at the rest position of the mandible than the centric occlusion in terms of the facial plane. 4. There are no differences between males and females at the rest position of the mandible and the centric occlusion in the meaning of variation. 5. There are no differences among the three methods from the view of lines and angles of the roentgenocephalogram.
Adult ; Deglutition ; Female ; Humans ; Incisor ; Lip ; Male ; Mandible* ; Saliva ; Tooth

The present study was designed to elucidate the effects of the Co-60 r irradiation and/or calcium deficient diet on the dentin and cementum formation of rat molar. The pregnant three-week old Sprague-Dawley rat were used for the study. The experimental group was divided into two groups, irradiation/normal diet group and irradiation/calcium-deficient diet group. The control group was non-irradiation/normal diet group. The abdomen of the rats at the 19th day of pregnancy were irradiated with single absorbed dose of 350 cGy. The rat pups were sacrificed on the 14th day after delivery and the maxillae including molar tooth germ were taken. The specimens including the 1st molar tooth germ were prepared to make tissue sections for light and trasmission electron microscopy. Some of tissue sections for light microscopy were stained immunohistochemically with anti-fibronectin antibody. The results were as follows ; 1. The Hertwig s epithelial root sheath cells, which are related to the differentiation of the tooth-forming cells, showed irregular cellular arrangement, decrease of intercellular junctional complex, and decreased immunoreactivity to the fibronectin after irradiation. These were more severe in the irradiation/calcium-deficient diet group. 2. The cementoblasts at the cementum-forming area showed chormatin clupings after irradiation. The immu noreactivity to the fibronectin was weaken after irradiation, especially irradiation/calcium-deficient diet group. 3. The odontoblast at the dentin-forming area showed increase of lysosomes in the cytoplasm and destruction of intercellular junctional complex. The irradiation/calcium-deficient diet group showed decrease of number and density of th electron dense particles and a large number of vacuoles scattered in the dentin matrix. The immunoreactivity was weaken.
Abdomen ; Animals ; Calcium ; Cytoplasm ; Dental Cementum* ; Dentin* ; Diet* ; Fibronectins ; Lysosomes ; Maxilla ; Microscopy ; Microscopy, Electron ; Molar* ; Odontoblasts ; Pregnancy ; Rats* ; Rats, Sprague-Dawley ; Tooth Germ ; Vacuoles

Caliceal diverticula are eventrations of the upper collecting system lying within the renal parenchyma and communicating with renal pelvis or a calyx through a narrow channel. The incidence on a routine IVP is approximately 0.21 to 0.45 percent and stone formation in a caliceal diverticulum has arised from 9.5 to 50 percent. Traditionally, treatment has included nephrotomy with extraction of the calculi and percutaneous nephrolithotripsy, but more recently ESWL has been challenged due to less invasive and safer procedure. We report the results of 11 patients with calculi in caliceal diverticula treated with EDAP LT-01 lithotriptor. All patients were followed during 2-11 months (average in 6.6) The results were obtained as follows ; 1. The symptoms were included chronic vague flank pain in seven, acute renal colic in two, epigastric discomfort in one and incidentally diagnosed in one. 2. The location of diverticula were upper third in seven, mid third in three and lower third of kidney in one. The stone size showed under 10mm in seven, 11-20mm in three and over 21mm in one. 3. The average numbers of treatment were 2.2 sessions and average storage was 102. 4. The complete success rate in 63.6 % (stone free rate in 45.5 %) and partial success rate in 27.2% were showed. 5. The complete relief of symptom was in eight (72.7% ), partial in one (9.1%) and persistent symptom in two (18.2 9t ). 6. Complication was showed only gross hematuria for 1 day in 63.6 %, but all patients recovered with conservative treatment. Therefore, the possibility of producing a satisfactory result (relief of symptom in 81.1%) and the low morbidity of ESWL suggest that this treatment may be appropriate for calculi in caliceal diverticuli.
Calculi* ; Deception ; Diverticulum* ; Flank Pain ; Hematuria ; Humans ; Incidence ; Kidney ; Kidney Pelvis ; Renal Colic

No abstract available.
Hyperhidrosis* ; Thoracotomy*

Many studies have reported structural or functional brain changes in patients with alcohol-dependence (ADPs). However, there has been an insufficient number of studies that were able to identify functional changes along with structural abnormalities in ADPs. Since neuronal cell death can lead to abnormal brain function, a multimodal approach combined with structural and functional studies is necessary to understand definitive neural mechanisms. Here, we explored regional difference in cortical thickness and their impact on functional connection along with clinical relevance. Fifteen male ADPs who have been diagnosed by the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) underwent highresolution T1 and resting-state functional magnetic resonance imaging (MRI) scans together with 15 male healthy controls (HCs). The acquired MRI data were post-processed using the Computational Anatomy Toolbox (CAT 12) and CONN-fMRI functional connectivity (FC) toolbox with Statistical Parametric Mapping (SPM 12). When compared with male HCs, the male ADPs showed significantly reduced cortical thickness in the left postcentral gyrus (PoCG), an area responsible for altered resting-state FC patterns in male ADPs. Statistically higher FCs in PoCG-cerebellum (Cb) and lower FCs in PoCG-supplementary motor area (SMA) were observed in male ADPs. In particular, the FCs with PoCG-Cb positively correlated with alcohol use disorders identification test (AUDIT) scores in male ADPs. Our findings suggest that the association of brain structural abnormalities and FC changes could be a characteristic difference in male ADPs. These findings can be useful in understanding the neural mechanisms associated with anatomical, functional and clinical features of individuals with alcoholism

PURPOSE: T cell-mediated immune responses, and particularly activation of polyfunctional T cells that simultaneously produce multiple cytokines, are necessary for the control of Mycobacterium tuberculosis. In the present study, we examined if DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) elicits polyfunctional T cell responses in mice. MATERIALS AND METHODS: C57BL/6 mice were immunized intramuscularly three times, at 3-week intervals, with RpfB-expressing plasmid DNA. For comparison, protein immunization was performed with recombinant RpfB in control mice. After immunization, RpfB-specific T cell responses were assessed by interferon-gamma (IFN-gamma) enzyme-linked immunosorbent spot assay and intracellular cytokine staining (ICS), and T cell polyfunctionality was assessed from the ICS data. RESULTS: RpfB DNA immunization induced not only humoral immune responses, but also CD8+ and CD4+ T cell responses. Immunodominant T-cell epitopes were identified within RpfB by assays with overlapping peptides. RpfB DNA immunization elicited a polyfunctional CD8+ T cell response that was dominated by a functional phenotype of IFN-gamma+/TNF-alpha+/IL-2-/CD107a+. CONCLUSION: RpfB DNA immunization elicits polyfunctional CD8+ T cell responses, suggesting that RpfB DNA immunization might induce protective immunity against tuberculosis.
Animals ; Complement Factor B* ; Cytokines ; DNA* ; Epitopes, T-Lymphocyte ; Immunity, Humoral ; Immunization* ; Interferon-gamma ; Mice ; Mycobacterium tuberculosis* ; Peptides ; Phenotype ; Plasmids ; T-Lymphocytes ; Tuberculosis ; Vaccines, DNA