No abstract available.
Anemia*

No abstract available.
Diabetes Mellitus, Type 1* ; Echocardiography*

Primary malignant melanornn of the vagina is rare, with only about 130 reported cases worldwide. They presumably arise from melanocytes that are present in the vagina in 3% of normal wornen. Vaginal melanoma accounts for less than 1% of melanomas and less than 3% of primary malignant tumors of the vagina. Most of patients complain vaginal bleeding, vaginal discharge, foreign body sensation in order. The best treatment of vaginal melanoma rernains eni.gmatic, Many authors indicate that radical surgery may be the pcferred approach and the number of reported cases treated with radical surgery is increasing. But other author comment that no significant change in survival is apparent with radical surgery. Overall prognosis is poor as most patients have deeply penetrating lesions at the time of diagnosis. Recently, not only the effort to increase the survival rate but the quality of life including sexual function after treatment is becoming an important issue about treatment ot cancer patients. We experienced a case of primary malignant melanoma of the vagina treated with radical surgery and restored the sexual function by vulvovaginal reconstruction using gracilis myocutaneous flap. So we report this case with brief literature review.
Diagnosis ; Foreign Bodies ; Humans ; Melanocytes ; Melanoma* ; Myocutaneous Flap ; Prognosis ; Quality of Life ; Sensation ; Survival Rate ; Uterine Hemorrhage ; Vagina* ; Vaginal Discharge

No abstract available.
Child* ; Humans

No abstract available.
Meningitis

No abstract available.
Neutropenia*

High matemal hemoglobin levels have been associated with intrauterine growth retardation and preterm delivery. We used it to examine the relationship between the lowest hemoglobin concentration in pregnancy, birth weight of newborns and preterm delivery. The study included 2586 pregnancies. The result as follows. A group with higher hemoglobin(above 14.5 g/dL) levels during pregnancy has higher incidence of low birth weight and preterm delivery than norrnal or low maternal hemoglobin levels.
Birth Weight* ; Fetal Growth Retardation ; Humans ; Incidence ; Infant, Low Birth Weight ; Infant, Newborn* ; Parturition* ; Pregnancy

A clinicostatistical study was made in 405 cases who were admitted to department of pediatrics, general surgery, urology, gynocology of N.M.C. for abdominal surgery from 1973 to 1978 and following results were obtained. 1. Distribution and incidece of surgical abdomen diseases showed acute appendicitis 107 cases(26.4%), inguinal hernia 82 cases(20.2%), intussusception 73 casese(18.0%) and intestinal obstructuction due to congenital origin 47 cases(11.6%). 2. Male was more predominant than female in proportion of 2.32:1. Age distribution revealed highest frequency in 10-15 years with 125 cases(30.8%) followed by 1 month to 1 year with 105 cases(25.9%). 3. In 47 casess of intestinal obstruction due to congenital origin, 3 common diseases were imperforated anus 14 cases, congenital megacolon 12 cases and congenitalpyloric stenosis 12 cases. 4. In 19 cases of acquired intestinal obstruction except intussusception and inguinal hernia, the most common cause was adhesion 10 sease(52.6%). 5. In 30 cases of abdominal mass, wilm's tumor was the commonest with 8 cases(26.7%). 6. In 19 cases of intestinal bleeding and perforation, accidental injury was the commonest cause with 12 cases(63.2%). 7. Highest incidence of diseases in relation to age group were as follows: newborn infant: intestinal obstruction due to congenital origin(96.7%), 1 month-1 year: intussusception (55.7%), 1-2year and 2-6year; inguinal hernia(46.3% and 50.0%), 6-10years and 10-15years; acute appendicitis(52.1% and 61.2%). 8. Overall mortality rate was 6.2%(25 out of 405 cases) and the highest mortality rate was noted in congenital anomaly with 23.1%(12 out of 52 cases).
Abdomen* ; Age Distribution ; Anal Canal ; Appendicitis ; Child* ; Constriction, Pathologic ; Female ; Hemorrhage ; Hernia, Inguinal ; Hirschsprung Disease ; Humans ; Incidence ; Infant, Newborn ; Intestinal Obstruction ; Intussusception ; Male ; Mortality ; Pediatrics ; Urology ; Wilms Tumor

Primary chronic intestinal pseudo-obstruction is a rare condition characterized by the symptoms and signs of the functional intestinal obstruction due to intestinal motility dysfunction in the absence of an anatomic obstruction. Megacystis associated with primary chronic intestinal pseudo-obstruction is very rare. Herein we report a case of megacystis associated with primary chronic intestinal pseudo-obstruction.
Gastrointestinal Motility ; Intestinal Obstruction ; Intestinal Pseudo-Obstruction*

Human papillomavirus(HPV) has been implicated in the development of uterine cervical cancer. Detectioe of the small amounts of HPV DNA in cervical cells has been very difficult. The polymerase chain reaction(PCR) is a new technique that can specifically amplify target DNA to facilitate its detectiion. PCR technique wes used to detect HPV types 16 and 18 in cervical specimeas obtained from nnormal cervix(20 cases), dysplasia(25 cses), carcinoma in situ(21 cases), microinvasive cancer(ll cases), and invasive cancer(46 cases). And then, case of invasive carcinoma of the uterine cervix were analyzed to determine that the presence of specific human papillomavirus DNA in the neoplasm was a contributing factor to their outcome. The detection rate of HPV 16 DNA in normnal cervix, dysplasia, ClS, microinvasive cancer, and invasive squamous cell carcinoma were 50.0%, 36.0%, 81.0%, 45.5%, and 58.7%, respectively. The detection rate of HPV 18 DNA in normal cervix, dysplasia, CIS, microinvasive cancer, and invasive squamous cell carcinoma were 0.0%, 8,0%, 4.8%, 0.0%, and 19.6%, respectively. of the factors evaluated in invasive cervical cancer, adenocarcinomatous component(p= 0.004) and tumor grade(p=0.015) were found to be correlated with HPV l8 infection. 5 of 8 women whose tumors contained glandular elements had HPV 18 DNA, whereas only 4 of 38 women whose tumors contained only squamous elements showed this infection. 6 of 9 women of HPV l8 infected tumors were grade 3 tumors as compared to only 7 of 28 of HPV 16 infected tumors. Age at diagnosis and nodal status in relation to HPV type 18 exhibited a trend but were not statisitically significant. These observations suggest that HPV type 18 may be associated with a more aggressive form of cervical cancer than HPV type 16.
Carcinoma, Squamous Cell ; Cervix Uteri ; Diagnosis ; DNA ; Female ; Human papillomavirus 16 ; Human papillomavirus 18 ; Humans* ; Polymerase Chain Reaction* ; Uterine Cervical Neoplasms*