1.Antiproliferative effect of difluoromethylornithine on human gastric and colorectal cancer cell lines in serum containing media.
Journal of the Korean Cancer Association 1992;24(3):359-364
No abstract available.
Cell Line*
;
Colorectal Neoplasms*
;
Eflornithine*
;
Humans*
2.IV bolus CT findings of the tuberculous granuloma: A case report.
Jae Ho CHO ; Jae Chun JANG ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(1):147-151
Isolated heaptic tuberculous granuloma with no coexistent tuberculosis elsewhere in the body is extremely rare. We report a case of pathologically proven tuberculous granuloma in the liver followed with both IV bolus and portal CT scans. The lesion on preenhanced CT scan showed undefinable isodensity. After IV bolus injection, it showed poor enhancement with central low-density and surrounding hyperdenity due to compensatory hypervascularity of the left lobe of liver in early phase. It showed peripheral rim enhancement in late phase and in delayed phase showed relatively homogeneous but slightly decreased contract enhancement. On portal CT scan, it showed a hypodense portal defect similar to other hepatic mass lesions. During follow-up studies, it was a slowly growing mass which was more easily detectable by prtal CT scans than bolus CT scans.
Follow-Up Studies
;
Granuloma*
;
Liver
;
Tomography, X-Ray Computed
;
Tuberculosis
3.Advantages of incremental dynamic CT in the evaluation of pancreatic and peripancreatic lesions.
Jae Chun CHANG ; Jae Ho CHO ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(4):787-793
Authors compared early phase scan of the IV bolus CT (two phase incremental bolus dynamic CT) with late enhanecd scan similar to the conventional contrast enhanced CT for evaluation of the advantages of the IV bolus CT with two viewpoints of the pancreatic or peripancreatic mass and peripancreatic lymphadenopathy in 68 patients-28 cases of the pancreatic cancer, 6 cases of the pancreatitis and 34 cases of the pancreatic or peripancreatic metastasis. On the diagnosis of the pancreatic or peripancreatic mass, IV bolus CT could show the lesion(s) more easily in 41% (Grade II; 13/31) and much more easily in 34% (Grade III; 10/31) when compared with conventional contrast CT scan. The diagnosis of the peripancreatic lymph node involvement was also easy in 51%(Grade II; 20/39) and much easier in 37% (Grade III; 14/39). We thought that these differences were originated from the increase of the contrast between the lesion and normal portion because the early enhanced scans reflected the active blood flow change more exactly. Therefore IV bolus CT had advantages in comparison with the conventional drip infusion contrast CT in the diagnosis of the presence and pathologic extension of the pancreatic and peripancreatic lesion.
Diagnosis
;
Infusions, Intravenous
;
Lymph Nodes
;
Lymphatic Diseases
;
Neoplasm Metastasis
;
Pancreatic Neoplasms
;
Pancreatitis
;
Tomography, X-Ray Computed
4.Advantages of incremental dynamic CT in the evaluation of pancreatic and peripancreatic lesions.
Jae Chun CHANG ; Jae Ho CHO ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(4):787-793
Authors compared early phase scan of the IV bolus CT (two phase incremental bolus dynamic CT) with late enhanecd scan similar to the conventional contrast enhanced CT for evaluation of the advantages of the IV bolus CT with two viewpoints of the pancreatic or peripancreatic mass and peripancreatic lymphadenopathy in 68 patients-28 cases of the pancreatic cancer, 6 cases of the pancreatitis and 34 cases of the pancreatic or peripancreatic metastasis. On the diagnosis of the pancreatic or peripancreatic mass, IV bolus CT could show the lesion(s) more easily in 41% (Grade II; 13/31) and much more easily in 34% (Grade III; 10/31) when compared with conventional contrast CT scan. The diagnosis of the peripancreatic lymph node involvement was also easy in 51%(Grade II; 20/39) and much easier in 37% (Grade III; 14/39). We thought that these differences were originated from the increase of the contrast between the lesion and normal portion because the early enhanced scans reflected the active blood flow change more exactly. Therefore IV bolus CT had advantages in comparison with the conventional drip infusion contrast CT in the diagnosis of the presence and pathologic extension of the pancreatic and peripancreatic lesion.
Diagnosis
;
Infusions, Intravenous
;
Lymph Nodes
;
Lymphatic Diseases
;
Neoplasm Metastasis
;
Pancreatic Neoplasms
;
Pancreatitis
;
Tomography, X-Ray Computed
5.Advantades of the intravenous bolus CT scan in differentiation of hepatic masses.
Jae Ho CHO ; Jae Chun CHANG ; Bok Hwan PARK
Journal of the Korean Radiological Society 1992;28(6):942-950
We performed IV bolus CT scan in 40 patients with final diagnosis of various hepatic masses in order to evaluate hemodynamic changes and differentiating characters of the lesions. Preenhanced, early and late phase post enhanced, and delayed CT scans were obtained with rapid IV bolus injection of contrast materials and table sliding method for pertinent scans. In hepatomas, early enhanced CT scan directly showed hypervascular change and active viable portion of the mass and late phase CT scan showed capsular enhancement. In addition, extracapsular invasion and post-embolization recurrence were more easily visualized. In hemangiomas, early and late enhancing types could be categorized according to the time of maximal enhancement. In metastatic liver malignancies and cholangiocarcinomas, specific findings were seen in early phase and delayed CT scans and not in conventional CT scan. In conclusion, IV bolus CT scan is a very useful CT method in demonstrating the characteristic hemodynamic patterns and in differential diagnosis of the hepatic masses.
Carcinoma, Hepatocellular
;
Cholangiocarcinoma
;
Contrast Media
;
Diagnosis
;
Diagnosis, Differential
;
Hemangioma
;
Hemodynamics
;
Humans
;
Liver
;
Methods
;
Recurrence
;
Tomography, X-Ray Computed*
6.Significance of the AFP Level and HBsAg in Differentiation of Hepatic Masses.
Jae Woon KIM ; Won Kyu PARK ; Jae Ho CHO ; Jae Chun CHANG ; Bok Hwan PARK
Yeungnam University Journal of Medicine 1996;13(2):302-307
Hepatic masses show different enhancing patterns in N bolus computed tomography: Hepatocellular carcinoma shows high-attenuation in the early enhancing phase and low-attenuation in the late enhancing phase, hemangioma shows peripheral dot-like high-attenuation in the early enhancing phase and central high-attenuation in the late enhancing phase, and metastatic cancer and cholangiocelluar carcinoma show peripheral high-attenuation rim in the early enhancing phase and central portion gradulally high attenuation in the late enhancing phase. but sometimes enhancing patterns of the hepatic masses are confuse. To evaluate the significance of the AFP level and HBsAg in differentiation of the hepatic masses, we retrospectively analyzed AFP level and HBsAg' in 228 pathologically or radiologically confirmed hepatocellular carcinomas, and 137 pathologically nonhepatocellular cacinomas. The results were as follows In hepatocellular carcinoma, AFP level above 20ng/ml was 77.8% and HBsAg positve was 72.6%. In nonhepatocellular carcinoma, AFP level above 20ng/ml was 3.7% and HBsAg positve was 16.1%. We concluded that AFP level and HBsAg are helpful to distinguish hepatocellular carcinoma from nonhepatocellular carcinoma, when IV bolus computed tomogram finding is uncertain.
Carcinoma, Hepatocellular
;
Hemangioma
;
Hepatitis B Surface Antigens*
;
Retrospective Studies
7.Agenesis of the right lobe of liver: a case report.
Kun Soo HAN ; Jae Chun CHANG ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(5):1024-1026
Congenital agenesis of the right lobe of liver is a rare anomaly and only 33 cases have been reported. CT showed absence of the right lobe of liver and compensatory hypertrophy of the other lobe. We report the CT findings of a new case of this anomaly with a review of the literatures.
Hypertrophy
;
Liver*
8.Psychological Study of Psoriatic Patients.
Kyung Jae PARK ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1985;23(3):269-278
The subjects of the present study were 111 patients admitted to a hospital and 304 healthy people living in similar condition. A self report symptom inventory, SCL-90(symptom check list-90) was used and the two groups were analysed and compared by many factors. The results of theis study are as follows. 1. All dimensional values of the psoriasis group were much higher than the normal healthy group. In order of significance: depression, anxiety, obsessive-compulsive, psychotism, interpersonal sensitivity, hostility, and somatization(all p<0.01). This result indicates a significantly heightened incidence of psychological problems among psoriatic patients. 2. There were significant differences between each clinical type. As a whole, common and pustular types showed highter dimensional scores than guttate type. 3. In the psoriasis group, subjects over 30 years old had higher scores except in somatization and paranoid ideation dimensions. However there was no significant relationship between age and dimensional scores. 4. Female psoriatic patients showed higher values than male patients on all dimensions excopt paranoid ideation. T verification showed significance in depression and hostility (p<0.05). 5. Analysed by marital status, generally unmarried patients had higher dimensional scores than married patients, but there was no significant differences. 6. In contrast with the control group, psoriatic patients of low educational status showed higher dimensional scores than patients of high educational status. 7. Analysed by job at onset of disease, student patients showed the lowest scores. There were significant differences for somatization(p<0.01) and paranoid (p<0.05) dimensional scores. 8. Analysed by the age of onset of disease, the patients who developed psoriasis before 20 years of ages showed higher dimensional scores than the patients, after 20 years of age. 9. Compared according to duration of the disease, dimensional scores rose in patients under 1 year duration decreased in patients of 1 to 2 years' duration and rose again in parients over 3 years' duratio. 10. As the accuracy of understanding about the disease decreased, the dimensional scores tended to be higher.
Adult
;
Age of Onset
;
Anxiety
;
Depression
;
Educational Status
;
Female
;
Hostility
;
Humans
;
Incidence
;
Male
;
Marital Status
;
Psoriasis
;
Self Report
;
Single Person
9.Clinical Observation of Skin Manifestation in the Patients with Hepatic Problems.
Inn Ki CHUN ; Kyung Jae PARK ; Young Pio KIM
Korean Journal of Dermatology 1985;23(6):774-779
From September 1983 to August 1984, the clinical observations regarding cutaneous manifestations of 26(j cases of in-patients in the Department of Internal medicine with hepatic problems were observed at the Department of Derrnatology in Chonnam University Eiospital, The results were as follows: In the 266 patients, 201 patients(75.6%) revealed various cutaneous manifestaiions; Among them vascular spider occured in 100 (37. 6%), bleeding tendency in 67(25. 2%), pruritus in 65(24.4%), jaundice in 59 (22.2%), palmar erythema in 59(22. 2%), and melanosis in 56(21. l%). The incidences of skin changes by pattern of liver disease were as follows; In acte hepatits, prurit;us(46.8%) and acute urticarial & maculapapular eruption(36. 4%) were found in order. In chronic hepatitis, vascular spider(42. 6%) and melanosis (27. 9%) in order. In cirrhosis, vascular spider (62. 5%) and bleeding tendency (42. 0%) in order. In hepatic cancer vascular spider (24. 2%) and jaundice (21. 2%) in order. There were no statistically significant differences in sex distribution. In the incidences of skin changes by age groups, jaundice(p<0. 01) and melanosis were more frequently observed in the patients under the age of 29 and vascular spider (p<0.01 ) and melanosis in the patients are the age of 50. The longer the duration of illness were, the higher the incidences of skin changes except jaundice were.
Erythema
;
Fibrosis
;
Hemorrhage
;
Hepatitis, Chronic
;
Humans
;
Incidence
;
Internal Medicine
;
Jaundice
;
Jeollanam-do
;
Liver Diseases
;
Liver Neoplasms
;
Melanosis
;
Pruritus
;
Sex Distribution
;
Skin Manifestations*
;
Skin*
;
Spiders
10.Analysis of branching patterns of middle hepatic artery using A-P and oblique view hepatic angiography.
Kun Soo HAN ; Jae Chun CHANG ; Bok Hwan PARK
Journal of the Korean Radiological Society 1992;28(5):696-701
A study on branching patterns of middle hepatic artery was performed in 109 patients with A-P and oblique view hepatic angiogram, which refered to size and location of quadrate lobe in CT and SMA portography We could analyze the branching patterns of middle hepatic artery (MHA) in 100 among the 109 patients. MHA arising as a first branch of left hepatic artery was the most common pattern (50%), and MHA arising from proper hepatic artery separately one from left hepatic artery was the next common pattern (35%). MHA originating from left gastric artery, or from anterior or posterior of the right hepatic artery was seen. MHA WAS not found as an accessory or replaced artery except as replaced common hepatic artery.
Angiography*
;
Arteries
;
Hepatic Artery*
;
Humans
;
Portography