No abstract available.
Cell Line* ; Chromosome Aberrations* ; Cytogenetics* ; Humans* ; Neuroblastoma*

BACKGROUND: Aprotinin, which is a nonspecific serine protease inhibitor, has an antiinflammatory and thrombogenic effect. However, it has an antithrombogenic effect during the cardiopulmonary bypass. This study was performed to evaluated the effects of aprotinin on the activated clotting time(ACT) and the total amount of the heparin used during the cardiopulmonary bypass. MATERIAL AND METHOD: From December 1998 to November 1999, 82 consecutive patients electively underwent open heart surgery at Gachon medical school. The patients were older than 18 years. Eighty two patients were classified into a control group(group C, n=36) and a aprotinin-treated group(group A, n=46). Body weight, height, body surface area(BSA), pump time(PT), aortic cross clamping time(ACCT), and body temperature(BT) were determined. Total amount of heparin and protamine during the CPB were also measured. ACT was determined before heparin administration, at 20, 40 and 60 minutes after heparin administration, and after protamine administration. RESULT: No significant differences were noted in either group in body weight, height, BSA, BT, and the total amoun of heparin and protamine. Group A demonstrated a significant(p<0.05) increase in age, PT, ACCT, and ACT at 20, 40, and 60 minutes after heparin administration. CONCLUSION: In summary, the use of aprotinin prime resulted in an increase in ACT. The total amount of heparin in aproinin-treated patient was similar to that of the control group in spite of having the prolonged pump time. Therefore aprotinin may reduce the requirement of heparin.
Aprotinin* ; Body Height ; Body Weight ; Cardiopulmonary Bypass ; Constriction ; Heart* ; Heparin* ; Humans ; Schools, Medical ; Serine Proteases ; Thoracic Surgery*

PURPOSE: Laser Assisted In Situ Keratomileusis(LASIK) is a preferred method to excimer laser photore-fractive keratectomy. In our paper, we insist that postoperative care, especially to avoid postoperative trauma. is considered to be important. CASE: A 22-years old boy was transferred into our hospital due to injuried left eye during playing basketball. His eye was received LASIK(OD: -7.00 Ds=-1.00 Dc Ax 50, OS: -8.00 Ds=-1.00 Dc Ax167) 1 years ago and then loss of LASIK flap developed due to this trauma. Injuried left eye of his was irrigated and then he weared therapeutic contact lens. RESULT: After wound healing, hazziness of traumatic cornea developed. He received lamellar keratoplasty for flap loss and corneal hazziness after postoperative accidental trauma. After receiving lamellar kerato-plasty, he maintains relatively good visual acuity(0.5 X -4.00 Dsph with K-840). CONCLUSION: As to review personel experience of the authors-lamellar keratoplasty for a flap loss and corneal hazziness after postopertive accidental trauma, we consider that it is an important vision-related complication of LASIK in the life and we report this unusual late complicated case with a review of available literature.
Basketball ; Cornea ; Corneal Transplantation ; Humans ; Keratomileusis, Laser In Situ* ; Lasers, Excimer ; Male ; Postoperative Care ; Wound Healing ; Young Adult

Salmonella infection can cause an asymptomatic intestinal carrier state or clinical diseases such as enterocolitis presenting abdominal pain, fever, vomiting, or diarrhea. Salmonella usually invades Peyer's patch of terminal ileum or ascending colon. Sepsis is not common and acute renal failure secondary to rhabdomyolysis is rare. The causes of rhabdomyolysis are trauma, excessive exercise, alcohol, seizure, metabolic abnormality, and infection. Infections account for less than 5% of the reported causes of rhabdomyolysis and resulting acute renal failure. The mechanisms underlying rhabdomyolysis due to infection are direct muscle invasion, toxin production, and nonspecific effects that can occur with infections such as fever, dehydration, acidosis, and electrolyte imbalance. We report a case of sepsis and acute renal failure secondary to rhabdomyolysis associated with Salmonella infection.
Colonoscopy ; Enterocolitis/complications/*diagnosis ; Humans ; Kidney Failure, Acute/*diagnosis/etiology ; Male ; Middle Aged ; Rhabdomyolysis/diagnosis/etiology/microbiology ; Salmonella Infections/complications/*diagnosis ; Sepsis/*diagnosis/etiology ; Tomography, X-Ray Computed

This is a case report of 47 year-old male patient with Huntington's chorea. Huntington's chorea is a progressive neurodegenerative disorder with autosomal dominant inheritance. The first symptoms of Huntington's chorea usually occur in the fourth to fifth decade and the gene is complete penetrance. The disease is characterized by both progressive motor abnormality, typically chorea, and intellectual deterioration commonly accompanied by prominent psychiatric symptoms including severe depression. Although the prevalence of Huntington's chorea is only 5-10 in 100,000 in Europe, the reported cases are extremely rare in this country until now.
Chorea ; Depression ; Europe ; Humans ; Huntington Disease* ; Male ; Middle Aged ; Neurodegenerative Diseases ; Penetrance ; Prevalence ; Wills

No abstract available.
Helicobacter pylori* ; Helicobacter* ; Urease*

No abstract available.
Liver* ; Retrospective Studies*

No abstract available.
Obstetrics*

No abstract available.
Basal Ganglia* ; Humans

No abstract available.
Kidney* ; Neuroectodermal Tumors, Primitive*