1.Changes of intercellular adhesion molecule expression and cytogenetic abnormalities during the differentiation process in human neuroblastoma cell lines.
Jong Jae KIM ; Yoon Jung CHOI ; Chul Woo KIM
Journal of the Korean Cancer Association 1993;25(4):563-571
No abstract available.
Cell Line*
;
Chromosome Aberrations*
;
Cytogenetics*
;
Humans*
;
Neuroblastoma*
2.Urine culture and serologic test for diagnosis of trichomoniasis in male patients with nongonococcal urethritis.
Eui Chul JEONG ; Jae Hong KIM ; Young Suck RO ; Chang Woo LEE
Korean Journal of Dermatology 1993;31(1):47-57
Trichomoniasis, a common and sometimes distressing condition in women, is caused by infection of the genitourinary tract by the pathogenic protozoan Trichomonris aginalis(T. vaginalis). Men may also be infected, although frequently without any symptoms, and most cases of trichomoniasis are sexually transmitted. The best evidence for an etiologic role for T. vaginalis is in nongonococcal urethritis(NGU). In epidemiologic studies, T,ginalis has been isolated from 1 to 68 percent in men with NGU. The nurnber of NGU is increasing rapidly than gonorrhea in deeloped nations, and in some developing countries, especially in Korea, In view of the difficulties in findng trichomonads by direct microsco by in men, urine culture and serodiagnosis plays an important role in the diagnostic work. Urine culture, indirect fluorescent antibody test(IFAT) and enzyme-linked immunosorbent assay (ELISA) were used to elecect T.vaginalis in 221 patients with male NGU. These patients visited the VD Clinic of ChoongKu Public Health Center in Seoul from May to August, 1989 and from March, 1990 to December, 1991. The results obtained were as follows.: 1. T. vaginalis was grown from only one of the 221 samples on TPS-1 meida. 2. In 208 NGU patients, there were 10(4.8%) positive reactions on IgG antibody in IFAT. 3. In 208 NGU patient, there were 14(6.7%) positive reactions to IgG antibody in ELISA. 4. No statistical significant correlation was found between then sults of IFAT and ELISA in individual patients. In conclusion, 1. Male trichomoniasis in patients with NGU was detected at a, significantly low rate. Due to the small number of patients in the test, further epidemiologic stidies of trichomoniasis in male NGU patient are necessary. 2. Serologic studies (IFAT and ELISA) have detected sorre trichomoniasis in male patients with NGU. These tests seem to be helpful in the diagnosis of male t-ichomoniasis.
Developing Countries
;
Diagnosis*
;
Enzyme-Linked Immunosorbent Assay
;
Epidemiologic Studies
;
Female
;
Gonorrhea
;
Humans
;
Immunoglobulin G
;
Korea
;
Male*
;
Public Health
;
Seoul
;
Serologic Tests*
;
Urethritis*
3.A Case of Huntington's Chorea.
Jae Woo CHUNG ; Byoung Chul LEE ; Jin Soo KIM
Journal of the Korean Neurological Association 1988;6(2):278-283
This is a case report of 47 year-old male patient with Huntington's chorea. Huntington's chorea is a progressive neurodegenerative disorder with autosomal dominant inheritance. The first symptoms of Huntington's chorea usually occur in the fourth to fifth decade and the gene is complete penetrance. The disease is characterized by both progressive motor abnormality, typically chorea, and intellectual deterioration commonly accompanied by prominent psychiatric symptoms including severe depression. Although the prevalence of Huntington's chorea is only 5-10 in 100,000 in Europe, the reported cases are extremely rare in this country until now.
Chorea
;
Depression
;
Europe
;
Humans
;
Huntington Disease*
;
Male
;
Middle Aged
;
Neurodegenerative Diseases
;
Penetrance
;
Prevalence
;
Wills
4.A Case of Loss of LASIK Flap Due to Accidental Trauma.
Journal of the Korean Ophthalmological Society 2001;42(5):788-792
PURPOSE: Laser Assisted In Situ Keratomileusis(LASIK) is a preferred method to excimer laser photore-fractive keratectomy. In our paper, we insist that postoperative care, especially to avoid postoperative trauma. is considered to be important. CASE: A 22-years old boy was transferred into our hospital due to injuried left eye during playing basketball. His eye was received LASIK(OD: -7.00 Ds=-1.00 Dc Ax 50, OS: -8.00 Ds=-1.00 Dc Ax167) 1 years ago and then loss of LASIK flap developed due to this trauma. Injuried left eye of his was irrigated and then he weared therapeutic contact lens. RESULT: After wound healing, hazziness of traumatic cornea developed. He received lamellar keratoplasty for flap loss and corneal hazziness after postoperative accidental trauma. After receiving lamellar kerato-plasty, he maintains relatively good visual acuity(0.5 X -4.00 Dsph with K-840). CONCLUSION: As to review personel experience of the authors-lamellar keratoplasty for a flap loss and corneal hazziness after postopertive accidental trauma, we consider that it is an important vision-related complication of LASIK in the life and we report this unusual late complicated case with a review of available literature.
Basketball
;
Cornea
;
Corneal Transplantation
;
Humans
;
Keratomileusis, Laser In Situ*
;
Lasers, Excimer
;
Male
;
Postoperative Care
;
Wound Healing
;
Young Adult
5.A Study of the Correlation between Prognostic Factors of Human Gastric Carcinomas and the Expression of CD44.
Ho LEE ; Hyung Chul KIM ; Woo Sung MOON ; Myoung Jae KANG
Korean Journal of Pathology 1997;31(9):873-883
This study was performed to investigate the relationship between CD44 expression and depth of, tumor invasion histopathologic differentiation, tumor size, lymph node metastasis, and proliferating capacity of tumor cells in the gastric carcinoma. In 20 cases of early gastric carcinoma (EGC) and 40 cases of advanced gastric carcinoma (AGC), the immunohistochemical staining for CD44v3, CD44v5, and PCNA gave the following results. 1) In all 60 cases, the positive rates for CD44v3 and CD44v5 were 18.3% and 71.7%, respectively. 2) CD44v5 was expressed in 45% of EGC and 85% of AGC. 3) Larger tumors exhibited higher positive rates for CD44v5. 4) There were 28 cases of lymph node metastases out of 43 cases of CD44v5- positive primary gastric carcinomas (65.1%), and there were 4 cases of lymph node metastases out of 17 CD44v5-negative cases (23.5%). 5) There was no relationship between CD44v5 expression and PCNA index. Because the tumors that exhibit deep invasion, and large in size and have lymph node metastses tend to have more frequent expression of CD44v5, CD44v5 may be one of the useful prognostic markers for gastric carcinoma.
Humans*
;
Lymph Nodes
;
Neoplasm Metastasis
;
Proliferating Cell Nuclear Antigen
6.Infantile Hypertrophic Pyloric Stenosis Treated with Intravenous Atropine Sulfate.
Jae Woo LIM ; Hee Sook SON ; Kye Shik SHIM ; Kyu Chul CHOEH ; Tae Il HAN
Journal of the Korean Pediatric Society 2000;43(6):763-768
PURPOSE: The pharmacologic effect of atropine on HPS can be considered to control pyloric muscle spasm. Therefore, we studied the effects of intravenous atropine sulfate on the clinical course of HPS, and periodically observed the ultrasonographic appearance of the pyloric muscles after atropine treatment. METHODS:From April 1998 to May 1999, 14 infants who were diagnosed with HPS were treated with intravenous atropine sulfate. Intravenous atropine sulfate was administered at an initial dose of 0.04mg/kg/day, which was divided into 8 equal doses. The daily dose was increased by 0.01 mg/kg/day until vomiting was controlled for an entire day while infants received unrestricted oral feeding. Ultrasonographic examinations were performed during hospitalization and repeated at least every 2 months until normalization of pyloric muscles was confirmed. RESULTS: Intravenous atropine was effective in 12 of 14 infants with HPS and the conditions of 9 of them improved. Two infants who were not free from vomiting despite a week of intravenous atropine sulfate treatment underwent pyloromyotomy. A series of ultrasonographic examinations were done after vomiting had improved with intravenous atropine sulfate. The ultrasonographic findings showed good passage of gastric contents through pyloric canals despite thickening of the pyloric muscles. CONCLUSION: Intravenous administration of atropine sulfate is an effective therapy for HPS and can be an alternative to pyloromyotomy. (J Korean Pediatr Soc 2000;43:763-768)
Administration, Intravenous
;
Atropine*
;
Hospitalization
;
Humans
;
Infant
;
Muscles
;
Pyloric Stenosis, Hypertrophic*
;
Spasm
;
Vomiting
7.Primary Primitive Neuroectodermal Tumor of the Kidney.
Woong Kyu HAN ; Won Jae YANG ; Sung Yong CHO ; Seung Chul YANG ; Woo Hee JUNG
Korean Journal of Urology 2000;41(3):456-458
No abstract available.
Kidney*
;
Neuroectodermal Tumors, Primitive*
8.Purification of the urease of helicobacter pylori and production of monoclonal antibody to the urease of helicobacter pylori.
Jae Im KIM ; Seung Chul BAIK ; Myung Je CHO ; Woo Kon LEE ; Kwang Ho RHEE
Journal of the Korean Society for Microbiology 1991;26(6):531-540
No abstract available.
Helicobacter pylori*
;
Helicobacter*
;
Urease*
9.A Case of Sepsis and Acute Renal Failure Associated with Salmonella Enterocolitis.
Chul Han KIM ; Ki Tae SUK ; Jae Woo KIM
The Korean Journal of Gastroenterology 2008;52(2):110-114
Salmonella infection can cause an asymptomatic intestinal carrier state or clinical diseases such as enterocolitis presenting abdominal pain, fever, vomiting, or diarrhea. Salmonella usually invades Peyer's patch of terminal ileum or ascending colon. Sepsis is not common and acute renal failure secondary to rhabdomyolysis is rare. The causes of rhabdomyolysis are trauma, excessive exercise, alcohol, seizure, metabolic abnormality, and infection. Infections account for less than 5% of the reported causes of rhabdomyolysis and resulting acute renal failure. The mechanisms underlying rhabdomyolysis due to infection are direct muscle invasion, toxin production, and nonspecific effects that can occur with infections such as fever, dehydration, acidosis, and electrolyte imbalance. We report a case of sepsis and acute renal failure secondary to rhabdomyolysis associated with Salmonella infection.
Colonoscopy
;
Enterocolitis/complications/*diagnosis
;
Humans
;
Kidney Failure, Acute/*diagnosis/etiology
;
Male
;
Middle Aged
;
Rhabdomyolysis/diagnosis/etiology/microbiology
;
Salmonella Infections/complications/*diagnosis
;
Sepsis/*diagnosis/etiology
;
Tomography, X-Ray Computed
10.Histopathologic Observation on the Cryptorchism.
Korean Journal of Urology 1983;24(6):1057-1060
A histopathologic observation was made on 24 patients with cryptorchism admitted to the Department of Urology, Seoul Adventist Hospital during the periods from November 1981 to April 1983. The following results were obtained. 1. The age distribution was ranged from 2 to 28 years and 6 to 10 years of age group was the most commonly affected (9 cases, 37.5%). 2. The most common type of cryptorchidism was the inguinal type (14 cases, 58.3%). The bilateral cryptorchismswere observed in 6 cases and unilateral 18 cases, among them right in 12 cases, left in 6 Cases. 3. On the histopathologic findings of testicular biopsy in 24 cryptorchid testes; per{tubular fibrosis which began before puberty was noted the earliest finding and basement membrane of seminiferous tubules were significantly thickening during puberty. Leydig cells were increased during puberty and they became normal level after puberty but spermatogenesis were not completely observed through all the age group.
Adolescent
;
Age Distribution
;
Basement Membrane
;
Biopsy
;
Cryptorchidism*
;
Fibrosis
;
Humans
;
Leydig Cells
;
Male
;
Puberty
;
Seminiferous Tubules
;
Seoul
;
Spermatogenesis
;
Testis
;
Urology