1.An experimental study on the effect of intermittent passivemobilization in the healing of rabbit's flexor tendons.
Han Koo LEE ; Sang Hoon LEE ; Choon Ki LEE ; Choon Sung LEE ; Young Do KOH ; Jae Hoon AHN
The Journal of the Korean Orthopaedic Association 1991;26(2):421-433
No abstract available.
Tendons*
2.Successful Rescue Therapy with Pumpless Extracorporeal Carbon Dioxide Removal in a Patient with Persistent Air Leakage Due to Empyema.
Jaeyoung CHO ; Yeon Joo LEE ; Jae Ho LEE ; Choon Taek LEE ; Young Jae CHO
Korean Journal of Critical Care Medicine 2017;32(3):284-290
A young metastatic lung cancer patient developed empyema due to an infection with carbapenem-resistant Acinetobacter baumannii. Hydropneumothorax was detected and managed by a tube thoracotomy. However, persistent air leakage through the chest tube was observed due to the presence of a bronchopleural fistula (BPF). As hypercapnic respiratory failure had progressed and the large air leak did not diminish by conservative management, a pumpless extracorporeal lung assist (pECLA) device was inserted. The pECLA allowed the patient to be weaned from mechanical ventilation and the BPF to heal. The present case shows the effective application of pECLA in a patient with empyema complicated with BPF and severe hypercapnic respiratory failure. pECLA enabled us to minimize airway pressure to aid in the closure of the BPF in the mechanically ventilated patient.
Acinetobacter baumannii
;
Bronchial Fistula
;
Carbon Dioxide*
;
Carbon*
;
Chest Tubes
;
Empyema*
;
Fistula
;
Humans
;
Hydropneumothorax
;
Hypercapnia
;
Lung
;
Lung Neoplasms
;
Respiration, Artificial
;
Respiratory Insufficiency
;
Thoracotomy
3.Primary culture of osteoblast.
Key Yong KIM ; Choon Sung LEE ; Soo Ho LEE ; Jae Dam LEE ; Gon Sup KIM
The Journal of the Korean Orthopaedic Association 1991;26(6):1860-1863
No abstract available.
Osteoblasts*
4.Effects of Parathyroid Hormone and Insulin on Proliferation in Osteogenic Sarcoma UMR-106-01 Cells.
Kyung MOON ; Choon Sung LEE ; Jae Suk CHANG ; Key Yong KIM ; Seong Who KIM ; Jae Dam LEE ; Kyung Sook PARK
The Journal of the Korean Orthopaedic Association 1998;33(2):466-471
Parathyroid hormone(PTH), a major bone hormone, inhihits DNA and collagen syntheses in osteohlast-like cells in vitro, but increase the proliferation of osteoblast in vivo as secn in hyperparathyroidism. On the other hand, insulin is known to increase DNA and collagen syntheses and modify the effects of PTH in osteoblast-like cells. We have examined the effects of PTH and insulin in rat osteosarcoma UMR-l06-01 cells and whether PTH plays a role in the insulin-mediated bone formation. When 1 nM PTH and 10 nM insulin were administered to VMR-l06-01 ceils, the rates of DNA synthesis were 124% and 136% of the untreated control, respectively. When the two hormones were administered serially by exposing to 1 nM PTH for 7 days followed by 10 nM insulin lor 24h, the largest increase was observed. The protein synthesis was also increased remarkahly when the two hormones were aclministered serially: the[3H]-leucine incorporation rates, compared to the control group, were 75% and l62% with PTH ancl insulin administration, respectively, but the rate was 297% with the serial administration of the two. The collaeen synthesis, as measured by the (3H)-proline incorporation rates were 60% and l64% with PTH and insulin administration, respectively, but 351% with serial administration, again showing a dramatic effect. These results showed that 1 nM PTH decreased DNA and collagen syntheses in UMR-l06-01 cells after both a 24h and a more prolonged exposure. Similar exposures to insulin tended to increase the syntheses. The comhination of PTH and insulin tended to increase the syntheses. hut not beyond the effect of insulin alone. However, the sequential administration of PTH and insulin markedly increases ihose rales relative to the simultaneous adminstration of these two hormones. Thus, it is possihle that sequential stimulation of PTH and insulin in hone matrix exerts an synergistic effect on hone formation in vivo.
Animals
;
Collagen
;
DNA
;
Hand
;
Hyperparathyroidism
;
Insulin*
;
Osteoblasts
;
Osteogenesis
;
Osteosarcoma*
;
Parathyroid Hormone*
;
Rats
;
Respiratory Sounds
5.Pancreatic invasion of gastric carcinoma in emaciated patients: the value of combined analysis with CT and upper gastrointestinal series.
Jae Mun LEE ; Hyun KIM ; Choon Yul KIM ; Yong Whee BAHK
Journal of the Korean Radiological Society 1992;28(2):223-228
The obliteration of a fat plane between the gastric carcinoma and the pancreas is a major criterion on CT scan for pancreatic invasion of gastric carcinoma. However, this sign is not always a reliable indicator of invasion, as the patients with gastric carcinoma are often emaciated. Producing a false positive CT findings. The purpose of our study is to improve the diagnostic accuracy of pancreatic invasion of gastric carcinoma in cases which the fat plane between the gastric carcinoma and the pancreas is obliterated in conventional CT scan. The authors performed lateral decubitus as well as supine CT scans and upper gastrointestinal series(UGIS) in 49 pathologically proven cases in which the fat plane was obliterated between the gastric carcinoma and the pancreas on conventional supine CT scan. Pancreatic invasion was suggested when the fat plane was obliterated persistently in the lateral decubitus view as well as the supine CT images and the involved gastric wall and adjacent pancreas maintained constant approximation despite postural change(CT+), and when the gastric tumor moved downward on the erect view of the UGIS no more than 1.5 time the height of the first lumbar vertevral body(UGIS+). Among 49 cases in which the fat plane between the gastric carcinoma and the pancreas was obliterated on supine CT scan, pancreatic invasion was confirmed pathologically in 11 cases(22.4%). Eight of 11 cases proven as pancreatic invasion were correctly diagnosed as pancreatic invasion by this combined analysis (CT+/UGIS+, 72.7%). Twenty seven of 38 cases proven as no pancreatic invasion were correctly diagnosed as no pancreatic invasion(CT-/UGIS-, 71.1%). Twelve cases showed CT +/UGIS-or CT-/UGIS+, so it was inconclusive whether there was invasion or not. The overall diagnostic accuracy was 71.4%. In conclusion, combined analysis with supine and lateral decubitus CT and UGIS is useful for improving diagnostic accuracy for pancreatic invasion by gastric carcinoma in patients of which the fat plane between the gastric carcinoma and the pancreas is obliterated on conventional supine CT.
Humans
;
Pancreas
;
Tomography, X-Ray Computed
6.Urological Complications Caused by Gynecologic Disorder.
Kwang Sae KIM ; Jae Man NAM ; Sung Choon LEE
Korean Journal of Urology 1973;14(2):115-118
It is well known that there always exists danger of injury to the urinary tract associated with gynecologic disorders and treatments. Herein the authors describe two different rare cases: bilateral complete ligations of the lower ureters following total hysterectomy and herniated urinary bladder as exstrophy of the bladder through vesico-vaginal fistula caused by cauterization of the uterine prolapse for treatment.
Bladder Exstrophy
;
Cautery
;
Fistula
;
Hysterectomy
;
Ligation
;
Ureter
;
Urinary Bladder
;
Urinary Tract
;
Uterine Prolapse
7.MR Imaging of Gastric Carcinoma' Comparison with CT.
Kyung Ah CHUN ; Kyung Sub SHINN ; Choon Yul KIM ; Jae Mun LEE ; Hyang Sun KIM
Journal of the Korean Radiological Society 1994;31(2):287-294
PURPOSE: To assess the value of MR imaging compared to CT for the staging of gastric carcinoma when body-wrap-around surface coil, intravenous glucagon, motion suppression technique and effervescent granules are used. MATERIAL AND METHOD: CT and MRI were performed for thirty-five patients with gastric carcinoma. Postcontrast CT scan was performed immediately after oral effervescent granules and Buscopan were given. Before MR imaging, BWA surface coil was wrapped around the upper abdomen. T1 coronal, sagittal and axial SE images (TRITE=400/15 msec) were obtained immediately after oral effervescent granules and glucagon were given. Respiratory compensation and presaturation techniques were used for each imaging. Three radiologists evaluated independently for randomly mixed 70 sets of CT and MR images. The signal intensity of gastric mass and enlarged lymph nodes were compared to the signal intensity of the adjacent pancreas, liver and spleen to evaluate any discriminating features between them. RESULTS: The accuracy in the diagnosis of pancreatic invasion was 83.8% on MRI and 74.3% on CT (p < 0.05). The accuracy of MRI and CT was 77.1% and 72.4% in detecting of gastric tumor respectively (p > 0.05), 73.3% and 68.6% in gastric serosal invasion (p> 0.05), 50.5% and 42.9% in lymph node metastasis (p > 0.05). The gastric mass and enlarged lymph nodes were hypointense to the intensity of pancreas and liver in more than 78% of cases. CONCLUSION: MRI was comparable to CT scan for the staging of gastric carcinoma. Therefore, MRI could be used as an alternative or adjunctive diagnostic modality in the staging of gastric carcinoma.
Abdomen
;
Butylscopolammonium Bromide
;
Compensation and Redress
;
Diagnosis
;
Glucagon
;
Humans
;
Liver
;
Lymph Nodes
;
Magnetic Resonance Imaging*
;
Neoplasm Metastasis
;
Pancreas
;
Spleen
;
Tomography, X-Ray Computed
8.Radiologic Findings of Secondary Systemic Amyloidosis Associated with Tuberculosis: A Case Report.
Kyung Sub SHINN ; Seong Tae HAHN ; Choon Yul KIM ; Jae Mun LEE
Journal of the Korean Radiological Society 1995;33(1):97-99
Amyloidosis is a rare systemic disease caused by extracellular deposition of insoluble protein. Systemic amyloidosis is subclassified into idiopathic primary and secondary form. The cause of secondary amyloidosis includes tuberculosis, familial Mediterranean fever, rheumatoid arthritis and multiple myeloma. We report a case of tuberculosis-related, secondary systemic amyloidosis which involved liver, spleen, kidneys, stomach, urinary bladder and lymph nodes.
Amyloidosis*
;
Arthritis, Rheumatoid
;
Familial Mediterranean Fever
;
Kidney
;
Liver
;
Lymph Nodes
;
Multiple Myeloma
;
Spleen
;
Stomach
;
Tuberculosis*
;
Urinary Bladder
9.Follow-Up of Stage A Carcinoma of the Prostate.
Jae Shin PARK ; Sung Choon LEE
Korean Journal of Urology 1990;31(3):372-377
The prognosis and proper treatment of Stage A carcinoma of the prostate remain unsettled. We report 19 patients with State A prostate cancer diagnosed between 1970 and 1988. Mean duration of follow-up was 4.3 years with a range of one to eleven years. Five patients(26.3%) suffered extensive local(4) and metastatic(1) disease progression. Extent and grade of disease were thought to depend upon the two factors that accurately predicted progression. Only one patient(7.7%) with a low grade lesion(Gleason total score 2 to 4) had progression for nine years of follow-up and only patient(10%) with less than 5 percents of cancer had progression. These patients were classified as stage A1 and we believe these ratients require no further therapy. Or the 9 patients with more than 5 percent of cancer, 4 patients(44.4%) had progression. These patients were classified as stage A2 and more aggressive management was thought to be needed.
Disease Progression
;
Follow-Up Studies*
;
Humans
;
Prognosis
;
Prostate*
;
Prostatic Neoplasms
10.Initial results of adenoma culture for adenoma-carcinoma continuum in the colorectal tumor.
Jin Cheon KIM ; Kyoo Yeon PARK ; Kun Choon PARK ; Jae Dam LEE
Journal of the Korean Cancer Association 1992;24(2):218-226
No abstract available.
Adenoma*
;
Colorectal Neoplasms*