No abstract available.
Humans* ; Ligaments*

There was decreasment of the domestic animal rabies, but increasment of the sylvatic animal rabies now a days in the world. We could see stable statistics of the ministry of health and social affairs annuala report, however, only rabies we could occationally find out suggestive human rabies by domestic animal for the slight more incidence in Korea. Now, we report on the three cases of sugg. Rabies in our children and review of literature. We think the improvement should be needed for postmortem examination that isn't taking by the Korean custom.
Animals ; Animals, Domestic ; Autopsy ; Child ; Humans ; Incidence ; Korea ; Rabies*

We have reported on a case of hemophilia B (Christmas disease) of 6 month old Korean who was have admitted to our hospital in duration of 7 days on Aug. 1974. Clinical study review of literature for a case were made briefly.
Hemophilia B ; Humans ; Infant

We have reported on a case of craniopharyngioma of 11 year old korean who had diabetes insipidus and the other typical symptoms. X-ray finding. Hormonal therapeutic study and review of literature for a case were made friefly.
Child ; Craniopharyngioma* ; Diabetes Insipidus ; Humans

It is necessary to install ventilation facilities in the laboratory and to regularly monitor harmful gases including formalin for safe environment of the dissection laboratory. However, there are no indicators that can identify the current status of ventilation facilities, safety equipment, and protective equipment in the dissection laboratory. In this study, the status of safety management of anatomical lab at domestic medical, dental, and oriental medical universities are investigated through an online questionnaire. Of the total 32 universities, 7 universities (21.8%) regularly monitor harmful gases such as formalin in the dissection lab, 13 universities (40.6%) do it on an irregular basis, and 12 do not do it at all. Seven universities (21.8%) are using the exhaust-type dissection table, 24 universities (75%) are not using it. Regarding the need for standards for manpower and facilities in the management of the anatomy lab, 7 universities (21.8%) are mediocre, 21 universities are necessary (65.6%), and 4 universities (12.5%) are very necessary. The responsibility for anatomy lab is 27 universities (84.3%) of the schools that responded as head professors of the department of anatomy, 3 universities (9.3%) of technicians, and 2 universities (6.2%) of the dean of the medical school. Regarding the need for standards for the anatomical lab, 7 universities (21.8%) are very necessary, 21 universities (65.6%) are necessary, and 4 universities (12.5%) are mediocre. Based on this data, the standard for the quality improvement and safety of anatomical education should be prepared.

To understamd the changes in parvalbumm- and calbindin-immunoreactive neurons and fibers during the spinal cord ischemia, expression of two kinds of calcium bindlng protein, parvalbumin (PV) and calbindin D-28K (calbindin), immunocytochemically an activities of cytochrome oxidase (CO) and acetylcholinesterase (AChE), histochemically global ischemic spinal cord of the rabbit were investigated under thiopental sodium anesthesia, adult rabbits(2,0-2.5 Kg) was cannulated through the left femoral artery with 4F Berman amgiographic catheter. Which was advanced 15 so that tbe tip of the catheter was in the ahdominal aorta just below the orign of the renal artery. After the rabbits were recovered from anesthesia, the balloon was inflated induce ischemia for15 minutes with recording abdominal aortic blood pressure. At 48 hours after reperfusion, the rabbits were fixed with transcardiac perfusion. In the sham-operated controls, the rabbit was treated same procedure except inflation of the ball. In tbe ischemic spinal cord, CO activitieS were generally decreased in the gray matter, especially in laminae III-V and AChE activities were slightly decreased in laminae X amd III-IV. The degree of immunoreactivities for PV and calbindin was decreased in whole gray matter of ischemic cord. In laminae II-III of the ischemic lumbar cord, number of PV amd calbindin-immunoreactive neurons was signilicantly decreased and vacuolations were observed. In laminae V-IX amd X of ischemic lumbar cord. The numbe of jmmunoreactive neurons was not changed, but degree of immunoreactivities for and calbindin was decreased. Thses findings suggest that PV and calbindin-immunoreactive neurons in laminae II-III are more vulnerable than other neurons to ischemic injury, and PV and calbindin may have some roles in hypoxic neuronal injury.
Acetylcholinesterase ; Adult ; Anesthesia ; Aorta ; Arterial Pressure ; Calbindins ; Calcium ; Catheters ; Electron Transport Complex IV ; Femoral Artery ; Humans ; Inflation, Economic ; Ischemia* ; Neurons ; Perfusion ; Rabbits ; Renal Artery ; Reperfusion ; Spinal Cord Ischemia ; Spinal Cord* ; Thiopental

We report the case of a rectal teratoma. A 62-year-old woman was referred to our department for evaluation of a rectal mass. She had a 3-month history of rectal bleeding and constipation. No palpable mass was detected using digital rectal examination. Colonoscopic examination demonstrated a protruding mass with a broad stalk in the posterior wall about 12 cm from the anal verge. A computed tomography scan showed a mass, which contained calcifications and fatty components, protruding into the rectal lumen. On operation, the mass was located in the upper rectum, and the right lateral portion of the upper rectum was adhesed to the right ovary. Thus, she had undergone a low anterior resection and right oophorectomy. The pathologic results confirmed a teratoma arising in the muscularis mucosa and the submucosa of the rectal wall.
Constipation ; Digital Rectal Examination ; Female ; Hemorrhage ; Humans ; Middle Aged ; Mucous Membrane ; Ovariectomy ; Ovary ; Rectum ; Teratoma*

PURPOSE: An experimental animal study was performed to compare the bone fusion capacity of an allograft and porous hydroxyapatite. MATERIALS AND METHODS: Three milliliters of allograft or porous hydroxyapatite particles were inserted between the 4th and 5th lumbar transverse processes of New Zealand white rabbits weighing 3-3.5 kg. The total number of rabbits was 30, which were divided randomly into 2 groups. The bone formation and fusion capacity were evaluated 12 weeks after surgery through the gross findings and manual palpation, as well as radiological, biomechanical, and histological studies. Six rabbits in the allograft group died during breeding but the autopsy finding did not show any evidence suggesting an infection or graft rejection. The allograft was harvested from the iliac crest of the rabbits of the same species aseptically and was preserved at ??80oC for at least 7 days before implantation. RESULTS: The fusion rates were 55.6% (5/9) and 66.7% (10/15) in the allograft and porous hydroxyapatite groups, respectively. The mean values of the tensile strengths were 140.7 N in the allograft group and 189.6 N in the porous hydroxyapatite group. Histological analysis of 2 specimens from each group revealed theporous hydroxyapatite group to show a slightly better osteoconduction capacity. CONCLUSION: The porous hydroxyapatite group showed better bony union capacity even though there was no significant difference between the 2 groups.
Allografts* ; Animals ; Autopsy ; Bone Regeneration ; Bone Substitutes* ; Breeding ; Durapatite* ; Graft Rejection ; Osteogenesis ; Palpation ; Rabbits ; Tensile Strength

The loss of the uterine epithelium surrounding blastocyst is important in bringing the trophoblast into close association with the endometrial stroma during embryonal implantation in several laboratory rodents. It is usually assumed that the epithelial cells die during this process, but the cause of epithelial cell death remains speculative. This study was performed to investigate the mechanism of epithelial cell death during implantation in the endometrium of rat uterus throughout days 5-9 of pregnancy by light and electron microscopy. Cathepsin-D reactivity, detected by imunohistochemistry, was localized to all viable epithelia, some degenerating epithelial and decidual cells between days 5-9 of pregnancy. DNA fragmentation, detected by TUNEL staining, was observed in degenerating epithelial and decidual cells throughout days 6-9 of pregnancy. Cellular fragments within lumen and phagosome within trophoblasts were reacted positively to TUNEL staining. Electron microscopy revealed that the epithelium lining the antimesometrial chamber was sloughed off into the lumen on day 6 of pregnancy. Its cell organelles appeared healthy but its nucleus was condensed and irregular shaped. The detached epithelial cells lining the antimesometrial chamber on day 7 of pregnancy contained condensed and fragmented nuclei, but exhibited different morphological pattern according to the intactness or loss of cytoplamic organelles and membrane. And these cells were surrounded and phagocytosed by trophoblasts. On day 7 of pregnancy, syncytial knots were formed, and later these knots and most of detached epithelial cells were severely degenerated. Some decidual cells nearby the lumen were also degenerated at this period. These results indicate that the epithelial cell death of rat uterine endometrium during implantation is mainly due to the process of apoptosis and these dying cells are removed by trophoblasts.
Animals ; Apoptosis ; Blastocyst ; DNA Fragmentation ; Endometrium ; Epithelial Cells* ; Epithelium ; Female ; In Situ Nick-End Labeling ; Membranes ; Microscopy, Electron ; Organelles ; Phagosomes ; Pregnancy ; Rats* ; Rodentia ; Trophoblasts ; Uterus*

Smith-Magenis syndrome (SMS) is characterized by distinctive facial features, developmental delay, cognitive impairment, and behavioral abnormalities and associated with interstitial deletion of chromosome 17p11.2. We report 2 cases of SMS with tetralogy of Fallot. The first patient was reported having a normal conventional karyotype 7 years ago. However, as she grew up, she showed more compatible findings with SMS in behavior and phenotype. On the second cytogenetic study, interstitial deletion of 17p11.2 was detected by conventional banding technique which had 550 band resolution and it was confirmed by metaphase fluorescence in situ hybridization (FISH) using D17S258 SMS probe (Oncor, Gaithersburg, MD, USA). The second patient showed subtle phenotypic feature except microcephaly and cardiac anomalies was confirmed as SMS by cytogenetic analysis and FISH. We suggest that FISH should be performed not to overlook the submicroscopic deletion when SMS is clinically suspected, even though cytogenetist can not detect any anomalies on the conventional cytogenetics. A confirmatory diagnosis using FISH would be helpful in terms of guiding medical management and leading to proper genetic counseling.
Cytogenetic Analysis ; Cytogenetics ; Diagnosis ; Fluorescence ; Genetic Counseling ; Humans ; In Situ Hybridization ; Karyotype ; Metaphase ; Microcephaly ; Phenotype ; Smith-Magenis Syndrome* ; Tetralogy of Fallot*