This study was designed to investigate the association between the period of engraftment and the nutritional status of patient's undergoing bone marrow transplantation for acute myelogenous leukemia (AML). Nutritional status was evaluated by body mass index (BMI), percentage of ideal body weight (PIBW), percentage of weight loss, and serum albumin, total protein (T protein), hemoglobin (HGB) and hematocrit (HCT) levels on the day prior to transplantation and on the day of bone marrow transplantation. The periods of engraftment were determined by absolute neutrophil counts (ANC) above 500 /mm3 from the day of bone marrow transplantation. The study subjects were 80 patients (55 males, 25 females) with acute myelogenous leukemia admitted to the University Hospital in Seoul. The result of this study is as follows : The nutritional status values of the majority of patients on the day prior to transplantation were in the normal range except for HGB and HCT; however, during hospitalization, all of the levels of the nutritional status values were significantly decreased. The periods of engraftment of the abnormal group according to their BMI, PIBW, HGB and HCT levels on the day of bone marrow transplantation showed no difference when compared to the normal group. However, the periods of engraftment of the abnormal group, according to the percentage of weight loss, albumin, and T protein levels were significantly decreased when compared to the normal group. Therefore, the nutritional status of patients at the time of transplant had a noticeable influence on the periods of engraftment. Our results suggested that nutritional status is a critical factor of engraftment in BMT during pre-transplant and post-transplant. Futhermore, we recommend that the process of nutritional preparation for the transplant should initiate immediately after the transplant decision has been made.
Body Mass Index ; Bone Marrow Transplantation* ; Bone Marrow* ; Hematocrit ; Hospitalization ; Humans ; Ideal Body Weight ; Leukemia, Myeloid, Acute* ; Male ; Neutrophils ; Nutritional Status* ; Reference Values ; Seoul ; Serum Albumin ; Weight Loss

Significant traumatic disruption of the ligaments about the knee can occur in a child. Recently several reports have described knee ligament, injuries with open growth plates. And these reports contradict the notion that complete tears of knee ligaments occur only after growth plates have closed. The youngest patient with medial collateral ligament injury reported before was a 4-year-old boy by Joseph and Pogrund in 1978. But authors experienced a case of ruptured medial collateral ligament of the knee in a 2-year and 1-month old boy, who seemed to be youngest with the ligament injury.
Child ; Child, Preschool ; Collateral Ligaments ; Growth Plate ; Humans ; Infant, Newborn ; Knee ; Ligaments ; Male ; Rupture ; Tears

No abstract available.

PURPOSE: We investigated if there are some differences in clinical charecteristics of acute epididymitis between child and adult and if ordinary therapeutic regimen based on antibiotics is the most appropriate one. MATERIALS AND METHODS: We reviewed medical records of 64 patients with acute epididymitis retrospectively, who took admission treatment from July, 1996 to June, 1998 at our hospital. These patients were divided into two groups, child and adult group, younger and older than 16 years respectively. The diagnosis of acute epididymitis was made by symptoms, physical examinations, doppler sonography, and/or radionuclide scan. Chronic epididymitis, recurrent epididymitis, patients taken antibiotics before admission, and surgical epididymis were excluded from this study. We investigated the age of the patients, symptoms, symptom duration and signs. Complete blood count, urinalysis, and urine culture were performed. Independent-samples T-test was used for the comparative analysis of the results. RESULTS: Symptoms including scrotal swelling and pain were not different between two groups significantly. Signs including scrotal tenderness, fever, and leucocytosis were not different between two groups significantly. However, there were statistically significant differences between two groups in studies of urine. Pyuria or positive urine culture were 20.8%(5 of 24) in child group and 52.5%(21 of 40) in adult group(p<0.001). CONCLUSIONS: In acute epididymitis, evidences of urinary tract infection were significantly lower in children than in adults. So, although further studies are needed to find out the exact cause of acute epididymitis, at least ordinary therapeutic regimen based on antibiotics would not be the best one for the majority of children without evidence of urinary tract infection.
Adult* ; Anti-Bacterial Agents ; Blood Cell Count ; Child* ; Diagnosis ; Epididymis ; Epididymitis* ; Fever ; Humans ; Male ; Medical Records ; Physical Examination ; Pyuria ; Retrospective Studies ; Urinalysis ; Urinary Tract Infections

PURPOSE: To establish normal reference ranges of urinary flow rate related to age, body surface area and voided volume in normal Korean pediatric females, uroflowmetry was performed and analyzed statistically. MATERIALS AND METHODS: Uroflowmetry was performed on total 270 normal pediatric females who ranged in age from 4 to 12 years(mean+/-SD: 7.23+/-1.97 years). The height and weight were measured then body surface area was calculated by Mosteller`s formula. The uroflow data(peak and average flow) were grouped by age(4 to 6, 7 to 9 and 10 to 12 years old) and body surface area( 1.1 and<1.1 m2) then plotted in volume-related nomograms. RESULTS: Mean values of peak and average flow rates were 13.33+/-4.44 & 7.51+/-2.6, 14.01+/-5.22 & 7.76+/-3.15, 20.40+/-6.84 & 10.89+/-3.97 ml/sec in each age group, and 13.57+/-4.87 & 7.61+/-2.96, 20.14+/-6.44 & 10.65+/-3.79 ml/sec in each body surface area group, respectively. Flow rates were increased significantly with voided volume, age and body surface area. Body surface area was found to be a more reliable index than age in the establishment of nomograms(p<0.05). CONCLUSIONS: Nomograms of peak and average flow rates of normal Korean pediatric female were presented. These may be useful for diagnosing lower urinary tract disturbances in pediatric female over a wide range of age, body size and voided volumes.
Body Size ; Body Surface Area ; Female* ; Humans ; Nomograms* ; Pediatrics ; Reference Values ; Urinary Tract

PURPOSE: The purpose of this study was to evaluate the clinical and radiological results of using the P.F.C(R) Sigma(TM) RP-F Knee System for high flex rotating platform-flexion total knee arthroplasty in 2 groups of patients with a preoperative range of motion (ROM) less than 90 degrees or more than 90 degrees, respectively. MATERIALS AND METHODS: From January 2005 to November 2006, eighty-two patients received the P.F.C(R) Sigma(TM) RP-F Knee System for high flex rotating platform total knee arthroplasty, and they were evaluated for a minimum of 3 years. We subdivided the patients into two groups: the preoperative ROM less than 90degrees group and the more than 90degrees group. The clinical results were assessed using the ROM, the Hospital for Special Surgery (HSS) score, the Knee Society Score (KSS) and the Western Ontario and MacMaster Universities Osteoarthritis (WOMAC) score. The radiological results were evaluated using the tibio-femoral angle and the presence of loosening or osteolysis of the components. RESULTS: The ROM increased in the two groups at the last follow-up. The mean ROM range at the last follow up was significantly increased more in the less than 90degrees group compared to that in the more than 90o group. The HSS score, KSS, and WOMAC score significantly increased in the two groups, but there was no statistical difference between the two groups. The tibio-femoral angle improved in the two groups. There was no aseptic loosening or osteolysis. CONCLUSION: The postoperative clinical and radiological measures were significantly improved using the P.F.C(R) Sigma(TM) RP-F Knee System on the short term follow-up, and especially for the patients whose preoperative ROM was poor.
Arthroplasty ; Follow-Up Studies ; Humans ; Knee ; Ontario ; Osteoarthritis ; Osteolysis ; Range of Motion, Articular

Osteoporosis represents reduced amount of bone mass per unit volume as compared with controls of the same age and sex. The purpose of this study was to show how bone mineral densities of spine and intertrochanteric area decrease with aging, to investigate the relationship between the bone mineral densities (BMD) of the two areas, and to obtain fracture threshold values. We measured BMD of lumbar vertebrae and intertrochanteric areas by Dual Energy X-ray Absorptiometry (DEXA) from 241 postmenopausal women. 190 normal postmenopausal women comprised non-fracture group and there were 50 fresh thoracolumbar fracture patient and 31 intertrochanteric fracture patients in whom the fractures were not caused by high energy trauma. The mean bone mineral density values of non-fracture group were significantly higher than those of fracture groups and significant correlation held between bone density of spine and that of intertrochanteric area in non-fracture group and fracture groups. The fracture threshold was 0.837 g/cm3 in spine fracture group and 0.792 g/cm3 in the intertrochanteric fracture group.
Absorptiometry, Photon* ; Aging ; Bone Density* ; Female ; Humans ; Lumbar Vertebrae ; Osteoporosis ; Spine

Selective cervical nerve root block is a widely utilized nonsurgical strategy for the management of cervical radicular and axial pain. The technique has been shown to be efficacious in relieving the patient's symptoms. Although effective, there are a range of possible complications associated with this procedure. In particular, acute spinal cord injury after cervical nerve root block is very rare, but it lead to serious functional impairment. The literature on acute spinal cord injury is very small and there have been no reports from Korea. We experienced a case of a patient with an acute injury of the cervical spinal cord after cervical nerve root block who was followed 28 months.
Humans ; Korea ; Radiculopathy ; Spinal Cord ; Spinal Cord Injuries

This study is to investigate the patients who had blepharoplasty for cosmetic purposes or facial nerve disorders. 21 patients were examined with an age from 17 to 63 years. Sixteen cases were classified as a normal group for investigation of the histopathologic change according to the age. The rest were patients of Bell's palsy(2), Botox(R) injection(2) and blepharospasm (1). We measured a mean diameter of myofiber and dimension's proportion of muscluar tissue per regular visual field. First, we measured a statistical significance according to the age in normal cases by grouping them into younger than 30-year-old, 30's, 40's, 50's and 60's. Second, we divided normal cases(16) into Group A and B by two bases for statistical analysis. In conclusion, although there were several differences as vacuolation, internalization of sarcolemnic nuclei between 35-year-old and 62-year-old patients in simple comparison, there was no uniform decrease according to the age. There were also no significant statistical changes in the value of a diameter of myofibers and dimension's proportion of muscular tissue according to the age in any of the two normal groups. But in Botox(R) injection and Bell's palsy, blepharospasm patients, two values showed remarkable difference compared to the normal group of same age.
Adult ; Bell Palsy ; Blepharoplasty ; Blepharospasm ; Facial Nerve Diseases ; Humans ; Middle Aged ; Muscular Atrophy ; Visual Fields

Multiple myeloma manifestated by necrotizing fasciitis is quite rare. Most of the patients affected with necrotizing fasciitis have some risk factors : Chronic general or local diseases, leukoenia, immunodeficiency diseases, malignancy, and an age of 50 years or more. We have experienced a case of necrotizing fasciitis associated with multiple myeloma presented as jaundice, pain, swelling of right buttock, ab-domiminal distension in 65-year-old man. His general status was improved after incision and drainage of wound and systemic chemotherapy. We recommend that multiple myeloma should be considered if necrotizing fasciitis is diagnosed.
Aged ; Buttocks ; Drainage ; Drug Therapy ; Fasciitis, Necrotizing* ; Humans ; Jaundice ; Multiple Myeloma* ; Risk Factors ; Wounds and Injuries