No abstract available.
Child* ; Humans ; Kidney Failure, Chronic*

Three cases of angiosarcoma of the breast are described. One case in a 66 year old woman was a solid mass and histologically showed poor differentiation leading to a death 14 months after the diagnosis. Another two in 46 and 25 year old females were large vascular masses showing moderate differentiation with endothelial tufting and papillary projections, and abdominal and contralateral mammary, and liver metastasis occurred within postoperative 10 months and 6 months in each case. A radical mastectomy and adjuvant chemotherapy in case 2 were not lifesaving. Although histologic degree of differentiation seems prognosis-related, angiosarcoma is the most malignant tumor of the breast.
Female ; Humans ; Neoplasm Metastasis

Fibrous hamartoma of infancy is a distinct clinicopathologic entity with unique microscopic findings and benign clinical course. This tumor is composed of intervening dense fibrocollagenous trabeculae, well defined mucoid areas and varying amounts of mature fat, which are arranged in organoid growth pattern. We report three typical cases of this tumor which were experienced during the recent two years at the Seoul National University Hospital. It is the first description on this tumor in Korean literature. Case 1 was a 10 month old boy who was admitted due to a mass in the right infra clavicular area for 6 months. The mass showed irregular and poorly circumscribed outer surface. Case 2 was a one month old girl who was presented with a diffuse ill defined hairy mass in the left buttock since birth. Case 3 was a 15 month old boy who was brought to the hospital due to well circumscribed scrotal mass fot 8 months. Microscopically all three cases showed very similar histological features. And all 3 cases are well after the removal of the tumors.
Hamartoma

OBJECTIVE: Because endometriosis is difficult to diagnose and has a high recurrence rate after treatment, a reliable serum marker of endometriosis is necessary. Therefore, the aim of this study is to measure the serum levels of CA125 and CA19-9 in patients with endometriosis before and after treatment and during recurrence, and to assess the usefulness of these levels in the diagnosis, clinical follow up and prediction of recurrence in endometriosis. METHODS: Eighty-eight patients who visited the department of Obstetrics and Gynecology of Ewha Mokdong Hospital from January 1994 to December 1998 and were diagnosed as endometriosis by laparoscopy or explo-laparotomy were enrolled as subjects. A retrospective analysis of serum CA125 and CA19-9 levels at 1 month before and 3 to 6 months after initiation of treatment was done. RESULTS: The serum CA125 and CA19-9 levels of endometriosis group(81.0+/-252.5, 36.6+/-53.4 ; mean+/-2SD, U/ml) before treatment was significantly higher than control group(11.6+/-12.8, 9.4+/-8.6)(p<0.05). Overall sensitivity rate for CA125, CA19-9 levels and both was 53.4%, 42.9% and 64.3% respectively. The sensitivity rate for endometriosis, stage 3 and 4(85.4%, 55.0%) was significantly higher than that, stage 1 and 2(p<0.05). The serum CA125 level in endometriosis group showed a significant increment according to stages(p<0.05) while the serum CA19-9 level showed an increasing trend(p=0.055) and both levels decreased significantly after treatment(p<0.05). The serum CA125 level was also higher at recurrence after treatment(p<0.05). CONCLUSIONS: The serum CA125 and CA19-9 levels are a useful marker for diagnosing severity of disease, monitoring efficacy of treatment and predicting recurrence in endometriosis.
Biomarkers ; Diagnosis ; Endometriosis* ; Female ; Follow-Up Studies ; Gynecology ; Humans ; Laparoscopy ; Obstetrics ; Recurrence ; Retrospective Studies

PURPOSE: This survey was done to describe parenting self-efficacy and beliefs in corporal punishment as they are related to child abuse. Also demographic variables that influence child abuse were investigated. METHOD: A cross-sectional study was conducted during the second week of April 2002. The 160 participants were parents of students in five elementary schools in the J area of Korea. They replied to a structured questionnaire, and 129 replies were included in the final analysis. The WIN SPSS program was used for the analysis. RESULT: Parenting self-efficacy, beliefs in corporal punishment and child abuse showed no significant differences according to gender of the children. Child abuse by parents has significantly negative correlation with parenting self-efficacy (r=-.369, p=.000), socioeconomic states of family(r=-.290, p=.001), educational level of mother(r=-.211, p=.027), educational level of father(r=-.342, p=.000), parent's age(r=-.200, p=.028). Stepwise multiple regression showed that parenting self-efficacy and beliefs in corporal punishment significantly influence child abuse in Korean parents. CONCLUSION: As parenting self-efficacy explained 49.7% of child abuse, it is the most important variable for preventing child abuse. Belief in corporal punishment was the second most important variable in preventing child abuse. These two variables explained 53.3% of variance in child abuse by parents.
Child Abuse ; Child* ; Cross-Sectional Studies ; Humans ; Korea* ; Parenting* ; Parents* ; Punishment* ; Child Health ; Surveys and Questionnaires

The purpose of this study was to compare dietary patterns, dietary behaviors and life styles before and after breast cancer surgery in Korea. The subjects were 220 females who underwent surgery for stage I-III breast cancer at general hospitals. Food intake, eating habits, snacks, eating-out, use of nutritional supplements and healthy foods, and drinking and smoking habits were studied using a questionnaire. SAS program was used for statistical analysis of the data. The results are as follows : 1) Most subjects were housewives aged more than 40 years. 2) After breast cancer surgery, intakes of fruits and vegetables were increased and those of meat, salty and spicy foods were decreased. 3) There was a significant difference in takes of caffeine beverages, snacks, fast foods and instant foods before and after breast cancer surgery. 4) There was a significant difference in meal regularity and skipping breakfast before and after breast cancer surgery. 5) The frequency of eating-out was decreased and low-fat foods, such as Japanese foods, were preferred after breast cancer surgery. 6) Nutritional supplements and natural healthy foods were used more after breast cancer surgery. 7) Most subjects were non-smokers and drank little alcohol and the rate of regular drinking significantly decreased after breast cancer surgery. Therefore, there was a significant difference in dietary patterns and behaviors resulting form breast cancer. Further more, dietary factors may be a contributing factor in the incidence at breast cancer in Korea.
Asian Continental Ancestry Group ; Beverages ; Breakfast ; Breast Neoplasms* ; Breast* ; Caffeine ; Drinking ; Eating ; Fast Foods ; Female ; Fruit ; Hospitals, General ; Humans ; Incidence ; Korea ; Life Style* ; Meals ; Meat ; Smoke ; Smoking ; Snacks ; Vegetables ; Surveys and Questionnaires

PURPOSE: This study was done to identify menstrual discomfort and dietary habits, and factors related to the menstrual discomforts. METHOD: Participants were 320 female middle school students in G city. The Menstrual Discomfort Questionaire(MDQ) and dietary habit lists were used as tools. RESULTS: Factors related to MDQ were found to be the VAS scores (r=.361, p=.002), a mount of menstrual bleeding (r=.131, p=.019), height (r=.134, p=.016), adequacy of meal time (t=7.19, p=.008), consumption of milk & milk products (F=3.20, p=.042) and, hot, salty & irritant foods (F=8.01, p=.000), eating more than 3 kinds of side-dishes with each meal (F=8.32, p=.000), and various protein foods (F=5.15, p=.006). In stepwise regression, 4 variables (VAS scores, height, hot, salty & irritant foods, more than 3 kinds of side-dishes with each meal) explained 20.3% of the variance in the total MDQ scores. CONCLUSION: Reduction of hot, salty & irritant foods and having more than 3 side-dishes with each meal would be effective in menstrual discomfort management. As well, good and, balanced dietary habits should be encouraged for early adolescent girls. To keep up with the ideal dietary habits, nutritional education & counseling should be continued. In a further study, a replication study with larger samples and more specified nutritional assessment are recommended.
Adolescent* ; Counseling ; Eating ; Education ; Female ; Food Habits* ; Hemorrhage ; Humans ; Meals ; Milk ; Nutrition Assessment ; Child Health

The synergistic effect of combining radiation therapy and hyperthermia kills significantly more cells than using either modality alone. The reason for enhanced cell killing from the combined treatment is that the two modalities are complementary. For histopathological exmination, 102 rats were divided into 4 groups as hyperthermia, radiation, hyperthermia combined with radiation and normal control groups. The effect of prior irradiation (6-15 Gy of X-ray) on the response of small and large bowel of rats to 40degree C-44degree C (for 30 minutes) microwave (2450 MHz) hyperthermia was investigated. The musculature of the small and large intestine remained intact and the circumference of the histological sections were not significantly altered by the heated at 43degree C for 30 minutes. Thermal enhancement ratios of normal tissue is 1.0. Thermal enhancement ratio was not increased in combination therapy by evaluation of histopathologic changes in small and large intestine.
Animals ; Fever* ; Homicide ; Hot Temperature ; Intestine, Large* ; Microwaves* ; Rats*

OBJECTIVES: Parents of child neuropsychiatic patients may have many stresses due to their children's illness. Characteristics and severity of diseases will influence to the stresses of parents. The authors investigated various factors and parents' social support having an effect on the parenting stress. METHODS: Children and parents in outpatients interviewed and completed measures assessing children's problem behaviors, parenting stress, general social support, and support related to parenting by Child Behavior Checklist, Parenting Stress Index, Medical Outcomes Study's Social Support Scale, and Parenting Support Scale. RESULTS: We could not find the differences in the total scores of CBCL, Social Support Scale, and Parenting Stress Index among major diagnostic groups. In the same diagnosis, no difference of parenting stress was found according to general social support. Parenting stress highly correlated with severity of problem behaviors measured by CBCL. CONCLUSION: Severity of problem behaviors perceived by parents most predicted parenting stress. Parenting stress correlated with support to parenting, but not with general social support. Managing of children's problem behaviors is the most immediate and effective method to diminish the parental stress of child neuropsychiatric patients.
Checklist ; Child Behavior ; Child* ; Diagnosis ; Humans ; Outpatients* ; Parenting* ; Parents*

PURPOSE: This study was undertaken to evaluate the efficacy of postoperative radiotherapy, and to investigate the prognostic factors for FIGO stages IB-IIB cervical cancer patients who were treated with simple hysterectomy, or who had high-risk factors following radical hysterectomy and pelviclymph node dissection. MATERIALS AND METHODS: Between March 1986 and December 1998, 58 patients, with FIGO stages IB-IIB cervical cancer were included in this study.The indications for postoperative radiation therapy were based on the pathological findings, including lymph node metastasis, positive surgical margin, parametrial extension, lymphovascular invasion, invasion of more than half the cervical stroma, uterine extension and the incidental finding of cervix cancer following simple hysterectomy.All patients received external pelvic radiotherapy, and 5 patients, received an additional intracavitary radiation therapy.The radiation dose from the external beam to the whole pelvis was 45 50 Gy.Vagina cuffirradiation was performed, after completion of the external beam irradiation, at a low-dose rate of Cs-137, with the total dose of 4488 4932 chy (median:4500 chy)at 5 mm depth from the vagina surface.The median follow-up period was 44 months (15 108 months). RESULTS: The 5-yr actuarial local control rate, distant free survival and disease-free survival rate were 98%, 95%and 94%, respectively.A univariate analysis of the clinical and pathological parameters revealed that the clinical stage (p=0.0145), status of vaginal resection margin (p=0.0002)andparametrial extension (p=0.0001)affected the disease-free survival.From a multivariate analysis, only a parametrial extension independently influenced the disease-free survival.Five patients (9%) experienced Grade 2 late treatment-related complications, such as radiation proctitis (1 patient), cystitis (3 patients)and lymphedema of the leg (1 patient).No patient had grade 3 or 4 complications. CONCLUSION: Our results indicate that postoperative radiation therapy can achieve good local control and survival rates for patients with stages IB-IIB cervical cancer, treated with a simple hysterectomy, as well as for those treated with a radical hysterectomy, and with unfavorable pathological findings.The prognostic factor for disease-free survival was invasion of the parametrium.The prognostic factor identified in this study for treatment failure can be used as a selection criterion for the combined treatment of radiation and chemotherapy.
Cervix Uteri* ; Cystitis ; Disease-Free Survival ; Drug Therapy ; Female ; Follow-Up Studies ; Humans ; Hysterectomy ; Incidental Findings ; Leg ; Lymph Nodes ; Lymphedema ; Multivariate Analysis ; Neoplasm Metastasis ; Pelvis ; Proctitis ; Radiotherapy ; Survival Rate ; Treatment Failure ; Uterine Cervical Neoplasms ; Vagina