1.Action Mechanisms of Hormone Binding to Cell Surface Receptors: 1) G-protein Coupled Receptor Signalling as Targets for Hormone Action: (1) Adenylate Cyclase Cascade.
Journal of Korean Society of Endocrinology 2000;15(3):311-332
No Abstract Available.
Adenylyl Cyclases*
;
GTP-Binding Proteins*
;
Receptors, Cell Surface*
2.G Protein Coupled Receptor Signaling: Recent Progress.
Journal of Korean Society of Endocrinology 1999;14(3):440-452
No abstract available.
GTP-Binding Proteins*
3.The Relationship between Pain Level and Perceived Family Support and Quality of Life in Musculoskeletal Patients with Chronic Pain.
Korean Journal of Rehabilitation Nursing 1998;1(1):93-109
The purpose of study is to identify the relation between pain level and perceived family support and quality of life in musculoskeletal patient with chronic pain. The subjects for the study consist of 155 patients with musculoskeletal pain that received medical treatment in hospital or by attending hospital in Chon-JU. The data were collected during the period from August 5 to August 14, 1998 by means of interviews with structured questionnaire. Data analysis was done by descriptive statistics, t-test, ANOVA, Pearson's correlation, Regression, Cronbach alpha using the SAS program. The result of this study were as follows: 1. The mean score of pain was 8.02, family support was 3.88 and quality of life was 3.07. 2. Hypothesis: The first hypothesis that 'The lower pain level is, the higher quality of life is' was accepted (r =-.2178, p= .0065) In addition, pain level of musculoskeletal patient with chronic pain provided predicted 4.7%(F =7.619. P = .0065) of quality of life The second hypothesis that 'The higher perceived family support is, the lower pain level is' was rejected (r=-.0376, p= .6425) The third hypothesis that 'The higher perceived family support is, is higher quality of life is' was accepted (r=.3212, p= .0001) In addition, perceived family support of musculoskeletal patient with chronic pain provided predicted 10.31%(F =17.597, P = .0001) of quality of life 3. General characteristics related pain were age(F=6.85, p=.0001 ),educational-level(F=9.29, p= .0001). occupation(F=5.81, p= .0037), marriage status(F=8.09, p= .0005), family numbers(F=5.73, p= .001), benefits of medical care(F=4.09, p= .0019), pain period(F=9.52, p= .0001), part of pain(F=2.33, p= .0352), pain period(F=3.08, p= .0181). 4. General characteristics related pain were sex(t=3.20, p= .0017), support sources(t=3.26, p= .0014), pain period(F=4.52, p= .0018). 5. General characteristics related pain were religion(t=3.11, p= .0022), benefits of medical care(F=3.61, p= .0293), pain duration(F=3.03, p= .0195). In conclusion, perceived family support in musculoskeletal patient with chronic pain is an important factor that can improve their quality of life. Therefore, nurses must establish nursing plan included patient's family when nurses carry out nursing intervention and education for patient so that a patient promote quality of life by maintaining optimal wellbeing.
Chronic Pain*
;
Education
;
Humans
;
Jeollabuk-do
;
Marriage
;
Musculoskeletal Pain
;
Nursing
;
Quality of Life*
;
Surveys and Questionnaires
;
Statistics as Topic
4.Urinary calculi in traumatic spinal cord injury
Dong Ran IHM ; Kyung Ja LEE ; Hyun Ja SHIN
Journal of the Korean Radiological Society 1982;18(1):149-156
The evaluation of urinary calculi was done in 84 patients of paraplegia and quadriplegia due to traumatic spinal cord injury. These patients were diagnosed by KUB and intravenous urography at National Veterans Hospital during 6 years from Jan. 1975 to Dec. 1980. The results were as follows; 1. Overall incidence of urinary calculi was 38.1 %; Incidence of renal calculi was 8.3%, ureteral calculi 4.8%, and urinary bladder claculi 32.1%. 2.Relation of neurological level and incidence of urinary calculi were as follows; Cervical injury in 34.8% upper thoracic injury in 40.0%, lower thoracic injury in 45.0%, and lumbar injury in 36.5%. 3. Laterality was not toplay a role information of urinary claculi. 4. The urinary calculi were developed 62.5% during the first 36 months following spinal cord injury. 5. The recurrence of urinary calculi was 40.6%; True recurrence was 15.6% and pseudo recurrence was 25.05.
Hospitals, Veterans
;
Humans
;
Incidence
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Kidney Calculi
;
Paraplegia
;
Quadriplegia
;
Recurrence
;
Spinal Cord Injuries
;
Spinal Cord
;
Thoracic Injuries
;
Ureteral Calculi
;
Urinary Bladder
;
Urinary Calculi
;
Urography
5.Intrathecal Phenol-glycerine Injection Therapy in Treatment of Intractable Cancer Pain .
Young In CHOI ; Soo Ja LEE ; In Hyun KIM
Korean Journal of Anesthesiology 1979;12(3):276-279
To a patient suffering from intractable pain due to the terminal state of cervix cancer, 7% phenol-glycerine solution was injected through the L2-L3 interspace. We obtained a good result of pain relief, but motor paralysis developed.
Humans
;
Pain, Intractable
;
Paralysis
;
Uterine Cervical Neoplasms
6.A Case of Imperigo herpetiformis.
Gong Myung HYUN ; Yang Ja PARK
Korean Journal of Dermatology 1978;16(1):79-83
Impetigo herpetiformis is a rare disease which has not been cleary defined in the European or American literature and is currently not fully appreciated or accepted as a clinical entity. According to Baker & Ryan, Impetigo herpetiformis was reffered to as the Exanthematous type of generalized pustular psoriasis. Impetigo herpetiformis starts suddenly without any preceding lesions of psoriasis as an extensive eruption of pustules on an erythematous base, and may. occur repeatedly during successive pregancies but may occur also without any known cause. A case of Impetigo herpetiformis affecting 30 year old 8 month pregnent woman, who has been suffering from generalized coaIesced pustular eruption with slight itching & buming sensation with fever & chill. 15days before, The Eruption began as an erythematous macule which developed pustules along the margin. There was extension by the development of fresh peripheral pustules and coalescence of these patches and central clearing. Diagnasis was confirmed by histopathologic finding and treated with cortico.teroid and Antibiotics, But improvement was not noted.
Adult
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Anti-Bacterial Agents
;
Female
;
Fever
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Humans
;
Impetigo
;
Pruritus
;
Psoriasis
;
Rare Diseases
;
Sensation
8.The Comparative Study on the Quality of Life, Health Perception, Self-efficacy of Ostomates by the Fecal Control Type.
Journal of Korean Academy of Adult Nursing 1999;11(2):278-287
The study was conducted to compare the quality life (QOL), health perception and self efficacy of the ostomates by the fecal control type. The study sbjects included 128 ostomates in Pusan, Daegu, Daejon and Incheon branches of the Korean Ostomy Association. Data collection was performed for 27 day periods from September 10th to October 6th. 1988. The instruments used in this study were the OL scale developed by Bang (1991). the health perception scale developed by Ware and translated to Korean by Lee (1987), the self efficacy scale developed by Kim( 1995). The analysis of the data was done by the use of descriptive statistics. Chi-square test, ANCOVA and Pearson Correlation with the SAS program. The results of the study are summarized below. 1. Only age was a significant difference between the two groups(p=.014). 2. The ostomate-related characteristics which showed significant differences were the number of participations in the ostomate meetings each month(p=.001). the care manager(p=.017), the number of defecations(p=.001). problems with the colostomy(p=.003), the duration of the ostomates(p=.00l). These variables were controlled using the ANCOVA. 3. The first hypothesis. "There will be differences at the level of the QOL according to the fecal control type" was supported(F=7.87, p .0059). 4. The second hypothesis. "There will be differences at the level of health perception depending on the fecal control type" was supported (F =8.68, p = .0039). 5. The third hypothesis, "There will be differences at the level of self efficacy depending on the fecal control type" was supported(F=4.58. p=.0344). 6. There were significant positive correlation between the QOL and health perception(r= .8225. p=.0001), and self efficacy(r=.6356, p=000l). From the above results, it can be concluded that colostomy irrigation is a good method to improve the QOL, health perception and self-efficacy. Therefore, colostomy irrigation is an important method for rehabilitation nursing use in the care of ostomates.
Busan
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Colostomy
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Daegu
;
Daejeon
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Data Collection
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Health Status
;
Incheon
;
Ostomy
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Quality of Life*
;
Rehabilitation Nursing
;
Self Efficacy
9.Investigation on Factors Influencing the Quality of Life of Arthritis Patients.
Journal of Korean Academy of Adult Nursing 2000;12(3):431-451
In this paper, I will examine the variables influencing the Quality of Life of arthritis patients and present basic materials which help arthritis patients have positive thinking in life and ultimately lead a satisfactory life. The subjects for this study are 231 inpatients and outpatients with arthritis living in J and K city in Chonbug Province. For the analysis of collected data I employed the SAS program. The variables for characteristics and the quality of life were analysed by descriptive statistics, T-test and ANOVA, and the relations among variables were analysed through Pearson Correlation; the Regression method was employed to predict the factors affecting quality of life. For the validity of reliance on measuring equipment Cronbach Alpha was used. The results of the study are as follows: (1)The mean score of quality of life of arthritis patients is 3.09(5 in the maximum). The general characteristics which affect the quality of life are age(F=5.13, p=0.0006), standard of education(F=6.49, p=0.0003), marriage status(F=7.77, p=0.0005), monthly pay(F=4.37, p=0.0020), medical benefits (F=4.85, p=0.0087), and supports(F=4.39, p=0.0050). For the disease-related characteristics, there is a significant difference in the 6 items: pain control method(F=5.92, p= 0.0002), physical therapy(F=3.25, p=0.013), whethere or not patients exercise(F=4.62, p=0.0000), regularity of exercise(F=4.79, p=0.0000), frequency of exercise(F=6.29, p=0.0001), and amount of exercise(F=4.62, p=0.0043). Depending on the type of arthritis, there is also a significant difference in the degree of pain felt. The patients with infectious arthritis suffer from pain the most, followed by those with gout, rheumatism and degenerative arthritis, in that order. Although statistics don't show any convincing evidence, those with gout perceive that they are in best health condition, followed by those with rheumatism, degenerative arthritis, and infectious arthritis, in that order(F=2.23, p=0.0669). (2)The quality of life of arthritis patients is correlated positively with perceived health status(r=0.56, p=0.0001), health promoting behavior(r=0.53, p=0.0001), family support (r=0.46, p=0.0001), amount of exercise (r=0.36, p=0.0001), ADL(r=0.36, p=0.0001), HLOC(r=0.32, p=0.0001), frequency of exercise(r=0.32, p=0.0001)in that order, while correlated negatively with the degree of pain felt(r=-0.32, p=0.0001), the number of pain regions(r=-0.19, p= 0.0041), and the duration of pain(r=-0.14, p=0.0279). (3)Regression analysis reveals that the most powerful predictor of the quality of life is perceived health status, which account for 31.11%. The other predictors of the quality of life, which account for 60.22%, are health promoting behavior(16.51%), family support(3.81%), ADL(2.52%), gender(1.86%), the number of family members(1.36%), level of pain(1.24%), duration of pain (1.08%), and level of education(0.67%). The results of the study show that perceived health status and health promoting behavior are the two most important variables. However, considering that the perceived health condition is difficult to control by nursing intervention, it is suggested that the level of expectation for patients, must be decided first, and the health promoting behavior and the family support influencing the quality of life must be taken into account as targets for nursing intervention. As a way of controlling the quality of life, I think that a more comprehensive approach comprising the above important variables along with demographic and general characteristics is needed. I also suggest that we must continue to explore the variables affecting the quality of life and include those variables in nursing intervention.
Arthritis*
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Arthritis, Infectious
;
Gout
;
Humans
;
Inpatients
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Marriage
;
Nursing
;
Osteoarthritis
;
Outpatients
;
Quality of Life*
;
Rheumatic Diseases
;
Thinking
10.Study of Spinal Braces on the Electrical Activity of Muscles of the Trunk in Low Back Syndrome
The Journal of the Korean Orthopaedic Association 1981;16(2):237-244
Lumbar braces, cast jackets and lumbar corsets are commonly prescribed for the relief of low back pain or the prevention of instability of lumbar or lumbosacral vertebrae. These devices have been presumed to achive their effect by (1) decreasing movement at the involved intervertebral joints, (2) shifting a portion of the load from the spine to the rest of the trunk by compressing the abdomen, (3) decreasing lumbar lordosis and therefore, mechanical stress on the spine and (4) providing sufficient support to allow relaxation of the muscles of the trunk. But it is doubtful that lumbar braces or corsets significantly decrease movement between lumbar vertebrae. To maintain the stability of the lumbar and lumbosacral spine, abdominal muscles and intrinsic muscles of the back play an important role. When these muscles weaken the lumbar lordosis becomes exaggerated possibly bringing about degenerative changes in the articular processes and approximation of the spinous processes. In severe cases results in the so-called kissing spine which causes low back pain. The pain may be relieved by use of lumbo-sacral corsets or knight braces, which diminish lordosis. However, there has been no scientific report on adequate types of braces, duration of use or muscle weakness resulting from its use as yet. The prupose of this study is to provide a theoretical braces for, planning adequate prevention and early treatment, so that labour loss from retirement or change of job due to low back pain could be minimized, permitting early return to employment and resumption of activities of daily living. In other words, this study concentrates on the indications for use and selection of which will produce optimum results in the treatment of patients with low back pain. The EMG was taken immediately after admission, and after 3 weeks of bed rest accompanied by pelvic traction with or without heating, and also it was taken after 6 weeks of use of brace. The results obtained from this study were as follows; 1. After bed rest the EMG activities were increased in back muscles, such as longissimus dorsi, multifidus and iliocostalis lumborum and in abdominal muscles of internus abdominis while decreased in rectus abdominis. 2. There has been no significant change after use of corset in acute cases while the muscle activities. were increased after use of lumbar corset in chronic cases. 3. Rectus abdominis was most senstively influenced by bed rest or use of brace both in acute and chronic cases. And it was the last to recover probably because it does not contract in ordinary alow walking. 4. Knight brace was considered to be preferable to lumbar corset in acute cases with evidence of weakness in abdominal muscles by EMG. 5. There was no difference between bed rest and use of brace in patients who had radiculopathy with functional difficulties or not.
Abdomen
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Abdominal Muscles
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Activities of Daily Living
;
Animals
;
Back Muscles
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Bed Rest
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Braces
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Employment
;
Heating
;
Hot Temperature
;
Humans
;
Joints
;
Lordosis
;
Low Back Pain
;
Lumbar Vertebrae
;
Muscle Weakness
;
Muscles
;
Paraspinal Muscles
;
Radiculopathy
;
Rectus Abdominis
;
Relaxation
;
Retirement
;
Spine
;
Stress, Mechanical
;
Traction
;
Walking