No abstract available.
Medicare*

PURPOSE: To develop a Korean version of FSFI for measuring the female sexual dysfunction and to verify both reliability and validity of the Korean version. MATERIALS AND METHODS: The FSFI English version was translated and back-translated with modification. Data from 116 married women residing in Gwangju city were collected through a questionnaire survey. The first and second surveys were conducted at two weeks interval for test-retest reliability. Content validity, constructvalidity, internal consistency reliability, and test-retest reliability of the FSFI Korean version were evaluated. RESULTS: Through Korean language localization of the English-version questionnaire, translations from English MATERIALS, content validity, preliminary survey and specialist panel discussions, the 19-section Korean-version questionnaire was completed. As a result of factor analysis by designating five as the number of its extracted factor, it is extracted five factors (six domains) as 'desire & arousal', 'lubrication', 'orgasm', 'satisfaction' and 'pain'. The total variance explained was 81.7%. The Cronbach's alpha coefficient for internal consistency was 0.96 and test-retest reliability was r=0.973 (p<0.001). CONCLUSIONS: The Korean version of FSFI is thought to have reliability and validity that may be used for Korean women subjects.
Female* ; Gwangju ; Humans ; Surveys and Questionnaires ; Reproducibility of Results ; Specialization ; Translations

PURPOSE: We measured the gastric cancer tissue uPA and plasminogen activator inhibitor-1 (PAI-1) levels and compared them to those of the peripheral and portal blood levels to evaluate the correlation. MATERIALS AND METHODS: Tissue uPA and PAI-1 levels were measured by ELISA assay (Monozyme, Netherland) in paired 85 normal and cancer tissues resected from gastric cancer patients. In 50 patients, blood uPA and PAI-1 levels were measured from pre- operative peripheral and portal blood, post-operative portal blood. RESULTS: Gastric cancer tissue uPA and PAI-1 levels increased from the early stage. The elevated cancer-to-normal ratios of the uPA and PAI-1 were constant from stage I to IV. There were correlations of uPA between normal and cancer tissues (r2=0.38) and between peripheral and pre-resection portal blood level (r2=0.64). There were no correlations between tissue PAI-1 level and blood PAI-1 levels. However, there were correlations in PAI- 1/uPA ratio between cancer tissue and peripheral blood (r2=0.25), peripheral blood and pre- resection portal blood (r2=0.60). CONCLUSION: Even if the cancer tissue levels of uPA and PAI-1 increased from the early stage of gastric cancer, only blood uPA level correlated with tissue uPA level. A modest correlation found in PAI-1/uPA ratio between cancer tissue and blood suggests applicability of blood PAI-1/uPA ratio in predicting tissue uPA, PAI-1 expression.
Enzyme-Linked Immunosorbent Assay ; Humans ; Plasminogen Activator Inhibitor 1 ; Plasminogen Activators ; Stomach Neoplasms* ; Urokinase-Type Plasminogen Activator*