2.A Case of Fatal Strongyloidiasis in a Patient with Chronic Lymphocytic Leukemia and Molecular Characterization of the Isolate.
Eshrat Beigom KIA ; Hamid Reza RAHIMI ; Hossein MIRHENDI ; Mohammad Reza NILFOROUSHAN ; Ardeshir TALEBI ; Farzaneh ZAHABIUN ; Hamid KAZEMZADEH ; Ahmad Reza MEAMAR
The Korean Journal of Parasitology 2008;46(4):261-263
Strongyloides stercoralis is a human intestinal parasite which may lead to complicated strongyloidiasis in immunocompromised. Here, a case of complicated strongyloidiasis in a patient with chronic lymphocytic leukemia is reported. Presence of numerous S. stercoralis larvae in feces and sputum confirmed the diagnosis of hyperinfection syndrome in this patient. Following recovery of filariform larvae from agar plate culture of the stool, the isolate was characterized for the ITS1 region of ribosomal DNA gene by nested-PCR and sequencing. Albendazole therapy did not have cure effects; and just at the beginning of taking ivermectin, the patient died. The most important clue to prevent such fatal consequences is early diagnosis and proper treatment.
Aged
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Albendazole/therapeutic use
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Animals
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Anthelmintics/therapeutic use
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Fatal Outcome
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Humans
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Ivermectin/therapeutic use
;
Larva
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Leukemia, Lymphocytic, Chronic, B-Cell/*complications/parasitology
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Male
;
Strongyloides stercoralis/*classification
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Strongyloidiasis/*complications/drug therapy
3.A case of loiasis.
Yoon Sun CHUN ; Soo Il CHUN ; Kyung Il IM ; Tae Kee MOON ; Min Geol LEE
Yonsei Medical Journal 1998;39(2):184-188
The prevalence of Loa loa infections in non-endemic areas such as Korea is very low, even though it is quite common in the endemic regions of West and Central Africa. We describe a patient who presented with temporary localized edema (classical Calabar swellings) after travelling to Cameroon and in whom the diagnosis of loiasis was made by ELISA. This is the second reported case of loiasis in Korea. As international travel is becoming more frequent, Loa loa infection should be considered in the differential diagnosis for patients with eosinophilia and Calabar swellings in Korea.
Adult
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Angioneurotic Edema/parasitology*
;
Animal
;
Antinematodal Agents/therapeutic use
;
Arm/parasitology*
;
Case Report
;
Enzyme-Linked Immunosorbent Assay
;
Human
;
Ivermectin/therapeutic use
;
Loa/isolation & purification
;
Loiasis/pathology*
;
Loiasis/parasitology*
;
Loiasis/complications
;
Male
;
Skin Diseases/pathology*
;
Skin Diseases/parasitology*