1.Clinical functional magnetic resonance imaging for pre-surgical planning--the Singapore General Hospital experience with the first 30 patients.
Helmut RUMPEL ; Ling Ling CHAN ; Judy S P TAN ; Ivan H B NG ; Winston E H LIM
Annals of the Academy of Medicine, Singapore 2009;38(9):782-786
<b>INTRODUCTIONb>Functional magnetic resonance imaging (fMRI) is a neuroradiological technique for the localisation of cortical function. FMRI made its debut in cognitive neuroscience and then eventually to other clinical applications. We report our experience with pre-surgical fMRI on a high field scanner, based purely on a clinical platform.
<b>MATERIALS AND METHODSb>The protocols included motor, auditory, visual and language fMRI. The choice of protocols was dependant on clinical request and lesion locale.
<b>RESULTSb>Retrospective analysis and audit of the fi rst 30 consecutive patients over a 12-month period revealed that about 85% of patients had a successful examination. In a pictorial essay, we demonstrate that patients with weakness in performing a motor task showed abnormal activations of the pre-motor and supplementary motor areas.
<b>CONCLUSIONb>FMRI data greatly enhances the pre-surgical planning process and the conduct of surgery when it is incorporated into the surgical navigation system in the operating theatre.
Adult ; Aged ; Diagnostic Techniques, Neurological ; Female ; Hospitals, General ; Humans ; Magnetic Resonance Imaging ; methods ; Male ; Middle Aged ; Preoperative Period ; Psychomotor Performance ; physiology ; Retrospective Studies ; Singapore