1.A Case of Confluent and Reticulated Papillomatosis Treated with Oral Isotretinoin.
Hyojin KIM ; So Hee PARK ; Do Hyeong KIM ; Jeong Nan KANG ; Jung Eun SEOL ; Ho Suk SUNG
Korean Journal of Dermatology 2016;54(5):397-398
No abstract available.
Isotretinoin*
;
Papilloma*
2.A Case of Cyclosporine-Induced Sebaceous Hyperplasia in a Renal Transplant Patient Successfully Treated with Isotretinoin.
Hwa Young JUNG ; Miri KIM ; Baik Kee CHO ; Hyun Jeong PARK
Annals of Dermatology 2016;28(2):271-272
No abstract available.
Humans
;
Hyperplasia*
;
Isotretinoin*
3.Henoch-Schonlein Purpura during Isotretinoin Therapy.
Yilmaz TURAN ; Mutlu CAYIRLI ; Mustafa TUNCA
Annals of Dermatology 2013;25(1):118-120
No abstract available.
Isotretinoin
;
Purpura, Schoenlein-Henoch
4.Henoch-Schonlein Purpura during Isotretinoin Therapy.
Yilmaz TURAN ; Mutlu CAYIRLI ; Mustafa TUNCA
Annals of Dermatology 2013;25(1):118-120
No abstract available.
Isotretinoin
;
Purpura, Schoenlein-Henoch
5.A Case of Hereditary Trichilemmal Cyst with Proliferating Trichilemmal Tumor.
Soo Jo KIM ; Byung Nam CHUN ; Hee Joon YU ; Sook Ja SON ; Jin Hee SON
Korean Journal of Dermatology 1988;26(2):259-263
We report a case of hereditary trichilemmal cyst with proliferating trichilemmal tumor in a 64-year-oid man, who has generalized 157, variable sized firm cutaneous nodules for 40 years. The cystic nodules are chiefly located on the scalp and trunk which showed characteristic histopathologieal findings of trichilemmal cyst and proliferating trichilemmal tumors. His son also has multiple trichilemmal cysts and his mother seems to have had clinically similar lesions. The patient and his son were treated with surgical excision and therapeutic trial of oral isotretinoin for 2 months. Isotretionoin was ineffective in the patient, but the lesions of his son were decreased in size.
Humans
;
Isotretinoin
;
Mothers
;
Scalp
6.13-cis-Retinoic Acid Treatment of Steroid Acne.
Kyung Hee WHANG ; Chang Jo KOH ; Sung Nack LEE ; Chung Koo CHO
Korean Journal of Dermatology 1983;21(1):85-89
No abstract available.
Acne Vulgaris*
;
Isotretinoin*
7.Widespread lichen planus pigmentosus in a 32-year-old Filipino male treated with low dose isotretinoin and topical tacrolimus
Nel Muriel B. Lee ; Heirich Fevrier P. Manalili ; Johannes F. Dayrit
Journal of the Philippine Dermatological Society 2020;29(1):122-124
INTRODUCTION: Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with
CASE REPORT: We report a case of a 32-year-old healthy male with widespread lichen planus pigmentosus, treated with clobetasol dipropionate 0.05% ointment, tacrolimus 0.1% ointment, and lowdose isotretinoin (0.1 to 0.2 mkd) showing a decrease in the progression and hyperpigmentation of patches and plaques after six months.
CONCLUSION: Based on our case and recent studies, low-dose oral isotretinoin, in combination with topical tacrolimus and topical corticosteroids, may show promising outcomes in treating cases of widespread lichen planus pigmentosus.
Isotretinoin
;
Dermoscopy
;
Pigmentation
8.Severe Papulopustular Rosacea with Demodicosis in a 47-year-old Filipino female: A case report
Aira Monica R. Abella ; Johannes F. Dayrit
Journal of the Philippine Dermatological Society 2021;30(2):65-68
Introduction:
Rosacea is a chronic relapsing inflammatory facial dermatosis often characterized by flare-ups and remissions
exclusively affecting the centrofacial skin.
Case report:
This is a case of multiple symmetric intensely erythematous papules, pustules, and plaques over both cheeks in
a 47-year-old Filipino female. Dermoscopy showed brown-yellowish structureless areas, straight vessels in a polygonal pattern,
dilated follicles, follicular plugs, ill-defined white rosettes, and non-specific scales. Skin punch biopsy showed spongiosis of
the epidermis and demodex folliculorum within the follicular infundibulum. The dermis revealed telangiectasia of blood vessels
and dense inflammatory infiltrates. Hypertrophy of sebaceous lobules was also seen. The patient was initially treated with oral
lymecycline 300mg twice a day for 2 weeks without improvement. Due to the persistence of centrofacial erythema, papules and
pustules, the patient was given prednisone 10mg once a day for 1 month and low dose isotretinoin 10mg once a day for 8 months
which resulted in significant decrease in erythema and number of existing lesions. To further decrease the inflammation con-
tributed by demodex mites, permethrin 5% cream twice a day for 1 month was applied. Long-pulsed Neodymium-doped yttrium
aluminum garnet (Nd:YAG) 1064 nm laser for a total of 10 sessions together with Isotretinoin 10 mg every other day effectively
maintained remission for 1 year and 5 months. Gentle skin care measures, sunscreen, metronidazole 0.75% cream once a day, and
desonide 0.05% cream twice a day for 1 week in cases of acute flares were maintained during the treatment course.
Conclusion
An armamentarium of topical and oral antibiotics, corticosteroids, isotretinoin and non-ablative long-pulsed
Nd:YAG 1064 nm laser showed significant improvement in the inflammatory papules, pustules, and centrofacial erythema of rosa-
cea and proves to be beneficial in the maintenance of its long-term remission.
Rosacea
;
Isotretinoin
;
Lymecycline
9.Recalibrated scales: The use of low-dose Isotretinoin in a case of Epidermolytic Ichthyosis-NPS1 in a Filipino child
Erickah Mary Therese R. Dy ; Shahara Abalos-Babaran ; Monette R. Faner ; Carmela Augusta F. Dayrit-Castro
Acta Medica Philippina 2021;55(5):592-596
Epidermolytic Ichthyosis (EI) is a rare non-syndromic keratinopathic ichthyosis without definitive treatment. This is a case of EI in a 5-year-old Filipino female who presented with hyperkeratotic scales sparing the palms and soles. Histopathology revealed epidermolytic hyperkeratosis. A trial of treatment with isotretinoin 0.3 mg/kg/day, together with keratolytic agents, urea lotion and lactic acid lotion, resulted in a marked decrease in the thickness of the scales and odor. Interestingly, rebound effects were noted at 0.6 mg/kg/day. Taking into account that EI presents with more skin fragility compared to non-EHK ichthyosis, the authors surmise that there may be a smaller treatment window for patients with EI, which is notably lower than recommended for ichthyosis in general.
Hyperkeratosis, Epidermolytic
;
Isotretinoin
10.Rhinophyma on hemangioma: A diagnostic conundrum
Danica-Grace R. Tungol ; Miguel Remigio T. Maralit ; Johannes F. Dayrit ;
Journal of the Philippine Dermatological Society 2020;29(1):93-95
INTRODUCTION: Rhinophyma, aside from persistent centrofacial redness is a major diagnostic criteria for rosacea. Phyma may be mistaken for hypertrophy of tissue due to an underlying hemangioma.
CASE REPORT: A 35-year-old female presented with few erythematous papules on the face and nose 19 years prior to consult. Lesions evolved into multiple erythematous nodules on nose and was mistaken for tissue hypertrophy due to an adjacent congenital hemangioma. Her hemangioma was treated with pulsed dye laser 16 years prior with noted decrease in size and erythema. Recently she noticed enlargement of her nose with persistent redness.
She presented with multiple firm, thick irregularly shaped erythematous nodules with prominent pilosebaceous pores and telangiectasia on the nose. Skin punch biopsy was done which revealed hypertrophy and lysis of sebaceous lobules with a moderately dense inflammatory infiltrate of lymphocytes. Histopathological diagnosis was rhinophyma. Patient was treated with low dose isotretinoin (0.20 mkd) with marked flattening of lesions in just one month.
CONCLUSION: Distinguishing phyma from tissue hypertrophy caused by hemangioma poses as a diagnostic challenge. Careful dermatological examination and histopathological findings will aid in correct diagnosis. Low dose oral isotretinoin is an effective treatment for rhinophyma.
Rhinophyma
;
Isotretinoin
;
Rosacea
;
Hemangioma
;
Hydrozoa