No abstract available.
CpG Islands* ; Methylation*

No abstract available.
Adenoma* ; Aged* ; Cartilage* ; Female ; Humans ; Islands*

Follicular hamartoma is a rare, benign adnexal tumor with varieties of clinical diversity. But, Histological feature is characterized by a proliferation of immature hair follicle in the dermis with multifocal islands and thickened perifollicular sheath. Pili multigemini is also a rare, developmental anomaly of hair growth with multiple hairs from two or more matrices and papillae in a single pilosebaceous unit. Its prevalence and pathogenesis are unknown. We describe herein a rare case of localized follicular hamartoma with pili multigemini suggesting the possibility of association on pathogenesis between them.
Dermis ; Hair ; Hair Follicle ; Hamartoma* ; Islands ; Prevalence

No abstract available.
Islands* ; Jeollanam-do* ; Primary Health Care* ; Ships*

The wood-rotting fungi of three Korean islands in the Yellow Sea, Soyeonpyung-do (SY), Oeyeon-do (OY), and Gageo-do (GG), were investigated from October 2004 to November 2005. During four sampling trips on each island, a total of 46, 44, and 44 specimens were collected from SY, OY, and GG, respectively. The identified wood-rotting fungi from SY included 29 species of 22 genera and nine families; OY had 31 species of 26 genera and 10 families; and GG had 34 species of 27 genera and 11 families. The majority of the fungi were in the Polyporaceae, which was represented by 23 genera and 30 species. Auricularia polytricha, Daedaleopsis tricolor, Daldinia concentrica, Hymenochaete cinnamomea, Hymenochaete yasudai, Hyphoderma setigerum, Lopharia mirabilis, Schizopora paradoxa, and Trametes versicolor were collected from all three islands.
Fungi ; Humans ; Islands ; Korea ; Mirabilis ; Polyporaceae ; Trametes

In forensic science practice, age is an important individual information, and one of the indicators to be considered first to depict features of the suspect. Recently, DNA methylation has become a research hotspot in age estimation because of its hig accuracy and stability. New progress has been made in specificity of DNA methylation sites, age estimation in multiple tissues, DNA methylation age estimation of minors, sensitivity of age estimation, forensic practical applications, etc. At the same time, several studies also established more accurate statistical modeling methods, eliminated differences between different detection platforms, found appropriate number of sites in models and analyzed the influence of environment and diseases. This review summarizes these to provide references.
CpG Islands ; DNA Methylation ; Forensic Genetics ; Humans

Cylindroma is an adnexal tumor which is mostly observed on the scalp. It usually occurs as a solitary lesion rather than multiple lesions. Histopathologically, the tumor is composed of numerous islands of basaloid cells which fit together like pieces of a jigsaw puzzle with surrounding hyaline sheaths. In Korea, there have been two reports of solitary cylindroma in the dermatologic literature, but no report of multiple cylindromas. We herein report a case of multiple cylindromas. A 34-year-old woman presented with three erythematous papules on her scalp, which developed four to five years before. Histopathologic findings on all papules revealed the typical appearance of cylindroma.
Adult ; Carcinoma, Adenoid Cystic* ; Female ; Humans ; Hyalin ; Islands ; Korea ; Scalp

PURPOSE: This study evaluated the spontaneous healing capacity of surgically produced cranial defects in rabbits with different healing periods in order to determine the critical size defect (CSD) of the rabbit cranium. METHODS: Thirty-two New Zealand white rabbits were used in this study. Defects of three sizes (6, 8, and 11 mm) were created in each of 16 randomly selected rabbits, and 15-mm defects were created individually in another 16 rabbits. The defects were analyzed using radiography, histologic analysis, and histometric analysis after the animal was sacrificed at 2, 4, 8, or 12 weeks postoperatively. Four samples were analyzed for each size of defect and each healing period. RESULTS: The radiographic findings indicated that defect filling gradually increased over time and that smaller defects were covered with a greater amount of radiopaque substance. Bony islands were observed at 8 weeks at the center of the defect in both histologic sections and radiographs. Histometrical values show that it was impossible to determine the precise CSD of the rabbit cranium. However, the innate healing capacity that originates from the defect margin was found to be constant regardless of the defect size. CONCLUSIONS: The results obtained for the spontaneous healing capacity of rabbit cranial defects over time and the underlying factors may provide useful guidelines for the development of a rabbit cranial model for in vivo investigations of new bone materials.
Animals ; Islands ; Rabbits ; Research Design ; Skull ; Wound Healing

PURPOSE: To report a case of eccrine spiradenoma that presented as an eyelid nodule. CASE SUMMARY: A 61-year-old female presented with a mass in the right upper lid margin; the onset time was unknown. An ophthalmic examination revealed no abnormalities except the eyelid nodule. The nodule was 3 mm in size with a firm, smooth surface and light pinkish color, and was located near the lid margin. Excision and biopsy of the nodule was performed. The pathological findings of the specimen obtained showed islands of 2 types of lobular cells. Larger, paler cells were grouped around the central area, darker and smaller cells on the periphery. These findings were compatible with eccrine spiradenoma. CONCLUSIONS: Eccrine spiradenoma should be considered a differential diagnosis of a solitary eyelid tumor.
Biopsy ; Diagnosis, Differential ; Eyelids* ; Female ; Humans ; Islands ; Middle Aged

We report here on a 71-year-old female who had well-demarcated erythematous patches, along with some pearly papules, on the right cheek. Histopathological examination of the lesions revealed a basaloid cell mass, which appeared to be a superficial basal cell carcinoma, and a small keratin-filled cyst that appeared to be a milium. A part of the milium was surrounded by the basaloid cells of tumor islands and milia later developed on the lesion of basal cell carcinoma. We suggest that basal cell carcinoma may be one of the causes of secondary milia.
Aged ; Carcinoma, Basal Cell ; Cheek ; Female ; Humans ; Islands