2.Severe Dengue with Hemophagocytosis Syndrome
Siti Hartini Ishak ; Lili Husniati Yaacob ; Azlina Ishak
Malaysian Family Physician 2020;15(1):47-49
Dengue is known to cause high morbidity and mortality worldwide. In recent years, there have been
increasing cases of dengue fever associated with a rare complication: hemophagocytic syndrome
(HPS), which is a dangerous disorder that carries high mortality. It is associated with infections,
autoimmune disorders, and malignancies. Prolonged duration of fever and cytopenia together
with multi-organ dysfunction out of proportion to the plasma leakage phase should alert clinicians
to consider this condition. In this case study, we highlight a 45-year-old woman with underlying
diabetes who was admitted due to dengue fever with warning signs. Her conditions deteriorated
quickly: she had spontaneous bleeding, evidence of plasma leakage, severe hepatitis, and coagulopathy on the 11th day of illness. With the support of other blood results, such as raised serum ferritin and lactate dehydrogenase, she was diagnosed with severe dengue with hemophagocytosis syndrome. She responded well to intravenous dexamethasone and recovered on the 19th day of illness.
3.Congenital arhinia – First published case in Malaysia
Ng Rui Lun ; Kokila Rajapathy ; Zainab Ishak
The Medical Journal of Malaysia 2017;72(5):308-310
Congenital arhinia is one of the rare craniofacial
malformation that may cause severe respiratory distress at
birth due to upper airway obstruction. Our patient, whose
abnormalities were only detected after delivery in our centre,
is the first reported case of congenital arhinia in Malaysia.
Contrary to popular belief that neonates are obligate nasal
breather, our patient adapted well to breathing through
mouth before an elective tracheostomy was performed on
day four of life.
Nose
4.A Preliminary Study of Blastocystis hominis in Some Development Areas in Alor Gajah District Melaka
Shafariatul Akmar Ishak ; Hidayatulfathi Othman ; Mazrura Sahani
Malaysian Journal of Health Sciences 2008;6(1):109-115
A descriptive study was conducted to evaluate the prevalence of Blastocystis hominis in children aged between 1-12 years old from randomly selected villages
in Alor Gajah district Melaka. The sampling was carried out from 1st to 7th of July of 2006. A total of 48 faecal samples were obtained from the children in
those studied villages. The faecal specimens were examined by direct saline wet moun, formalin ethyl acetate concentration and trichrome staining method.
It was found that 45.8% (22 out of 48) of the examined children were infected with Blastocystis hominis . Based on the results, the cumulative prevalence of
three methods used showed that Blastocystis hominis infection in female children higher compared to male children. Whilst the schooling children aged of 6 to
12 years had a higher prevalence than pre school children at the age of 1-5 years. In term of diagnosis, formalin ethyl acetate concentration method showed
prevalence of detection at 60.9%. It was followed by direct saline wet mount (43.5%) and trichrome staining at 34.8%.
5.Offshore Safety Awareness Training System
Ruzana Ishak ; Mohd Azri Baharuddin ; Noor Hamizah Hussin
Malaysian Journal of Public Health Medicine 2017;2017(Special Volume (1)):106-114
Safety is vital in any industry, including the offshore sector, which is classified as a major hazard industry. Health, Safety and the Environment (HSE) identified that the probability of accidents is high while working on the offshore sectors where it will exposed workers to many hazardous work activities. The appropriate measures to prevent accident in this sectors must be laid out clearly. This paper is to identify the effectiveness of safety awareness campaign and the continuity of the awareness among the workers to prevent injuries at offshore. To achieve this, we have identified the level of awareness and propose a guideline on areas of improvement. Prior of embarking to offshore, staff were exposed to safety awareness program for four weeks. After the program, we started with the pretest to all staff. They were posted offshore for 6 weeks. Within the period, the performance awareness of each staff is monitored through observation and interview. During the final week, the posttest questionnaire were administered to all staff. Two instruments were used for the quantitative data collection, which are Unsafe Act Unsafe Condition (UAUC) card; and Behavior Observation Tool (BOT) card. Questionnaire data were analyzed quantitatively. Paired-sample t-test was used for analyzing pre and post result. The results show that the mean was increased. Recent studies on the safety briefing highlighted several significant changes in terms of employee understanding toward safety. Safety awareness training has been introduced in the new safety briefing prior to offshore mobilization.
Offshore Sector
;
HSE
;
Hazards
;
Unsafe Act/Unsafe Condition
;
Behaviour Observation
6.Vision Status: Presbyopic Patient Undergone Corneal Inlay Procedure
Linsay Sundram Gnanasundram ; Rokiah Omar ; Bashirah Ishak ; Aloysius Joseph Low
Malaysian Journal of Health Sciences 2016;14(1):1-3
This study reports the vision status of a presbyopic patient who has undergone a corneal inlay procedure. The study
hopes to provide optometrists more insight on the procedure and the co-management involved in such a patient. The
patient, a 48 years-old Chinese woman with presbyopia underwent the corneal inlay procedure three years ago.
She had the inlay implanted in the non-dominant eye to aid near vision i.e. her left eye. The pre and post-operative
evaluations include distance and near visual acuity, fundoscopy, tonometry, Schirmer’s test, slit lamp evaluation, corneal
topography and corneal pachymetry. Near visual acuity for the left eye improved from N14 to N5 immediately after
the procedure. Even after 3 years of post-operative followup, the patient was still able to maintain her near vision. In
conclusion, the corneal inlay procedure helped to improve near vision of this presbyopic patient. Optometrist plays
a very important role in the co-management of such patients alongside with the ophthalmologist in terms of visual
functional assessments pre and post-surgery, counseling of the procedure and managing patients’ expectations.
Corneal Injuries
7.The Prognostic Factors Of Diabetic Retinopathy Severity Among Type 2 Diabetes Mellitus In A Tertiary Teaching Hospital
Nur Jannah Ambak ; Nor Azwany Yaacob1, Siti Raihan Ishak
Malaysian Journal of Public Health Medicine 2016;16(2):48-54
Diabetic retinopathy (DR) may result in progressive visual impairment and blindness which affects the diabetic patients‟ morbidity and quality of life significantly. The objective of this study was to determine the proportions and prognostic factors of DR severity among Type 2 diabetes mellitus patients. A cross sectional study was conducted at the Ophthalmology Clinic in a tertiary hospital using the medical record database from 2005 to 2011. A total of 216DR patients were randomly selected. The study outcome was DR severity which was classified into four grading based on the International Clinical Diabetic Retinopathy Scale. Descriptive statistics and Ordinal Logistic Regression were applied using Stata SE/11. The mean (SD) age of DR in this study was 56.06 (9.98) years old with almost equal sex ratio. Proportion of mild non proliferative diabetic retinopathy (NPDR) was 48.6% (95% CI: 40.0, 60.0), moderate NPDR was 28.2% (95%CI: 22.0, 40.0), severe NPDR was 6.9% (95% CI: 4.0, 11.0) and proliferative diabetic retinopathy (PDR) was 16.2% (95%CI: 10.0, 22.0). Diabetic patients that suffered from diabetes mellitus for more than 10 years, having nephropathy, every increased of HbA1c by 1% and higher total cholesterol were at increased risk of worsening DR.
8.Offshore Safety Awareness Training System
Ruzana Ishak ; Mohd Azri Baharuddin ; Noor Hamizah Hussin
Malaysian Journal of Public Health Medicine 2017;Special Volume(1):106-114
Safety is vital in any industry, including the offshore sector, which is classified as a major hazard industry. Health, Safet
y
and the Environment
(HSE) identified that the prob
a
bility of accidents is high while
working on the offshore sectors
where it will exposed workers to many hazardous work activities. The appropriate measures to prevent acc
i
dent in this
sectors must be laid out clearly. This paper is to identify the effectiveness of safety awareness campaign
and the conti-
nuity of the awareness among the workers to prevent injuries at of
fshore. To achieve this, we have identified
the level of
awareness and propose a guideline on areas of improvement. Prior
of embarking to offshore, staff w
e
re
exposed to safety
awareness pr
o
gram for four weeks. A
f
ter the program, we started with the pretest to all staff. They were posted off-
shore for 6 weeks. Within the period, the performance awareness of each staff is monitored through observation and
interview. During the f
inal week, the posttest questionnaire were administered to all staff. Two instruments were used
for the quantitative data collection, which are Unsafe Act Unsafe Condition (UAUC) card; and Behavior Observation Tool
(BOT) card. Questio
n
naire data were analy
zed quantitatively. Paired
-
sample t
-
test was used for analyzing pre and post
result. The results show that the mean was increased.
Recent studies on the safety briefing highlighted several significant
changes in terms of e
m
ployee understanding toward safe
ty. Safety awareness training has been introduced in the new
safety briefing prior to of
f
shore mobilization.
9.Mechanical and thermal properties of hydroxyaptite filled poly (methyl methacrylate) heat processed denture base material.
Mohamed SH ; Arifin A ; Mohd Ishak ZA ; Nizam A ; Samsudin AR
The Medical Journal of Malaysia 2004;59 Suppl B():25-26
The aim of this study was to evaluate the effect of powder-to-liquid ratio on the glass transition temperature (Tg) and the tensile properties of denture base material prepared from poly (methyl methacrylate) (PMMA) and hydroxyapatite (HA) previously treated with 3-trimethoxysilylpropyl methacrylate (gamma-MPS). Specimens for mechanical testing were prepared by adding composites powder (PMMA, BPO and HA) to the monomer (MMA and EGDMA) followed by hand mixing as in dental laboratory description usage. The glass transition temperature was studied by using differential scanning calorimetry (DSC). It was observed that the tensile properties and the Tg were affected by the powder-to-liquid ratio. The mechanical characterization of the materials were performed by using single edge notch-tension (SEN-T) specimens; the fracture toughness was slightly higher in formulation which contained HA filler compared to commercial denture base material.
Biomechanics
;
Calorimetry, Differential Scanning
;
*Denture Bases/standards
;
*Durapatite
;
*Materials Testing
;
Microscopy, Electron, Scanning
;
*Polymethyl Methacrylate
;
Tensile Strength
10.Characterization of collagen/chitosan films for skin regenerating scaffold.
Ismarul IN ; Ishak Y ; Ismail Z ; Mohd Shalihuddin WM
The Medical Journal of Malaysia 2004;59 Suppl B():57-58
Various proportions of chitosan/collagen films (70/30% to 95/05%) w/w were prepared and evaluated for its suitability as skin regenerating scaffold. Interactions between chitosan and collagen were studied using Fourier Transform Infrared spectroscopy (FTIR) and Differential Scanning Colorimetry (DSC). Scanning Electron Microscope (SEM) was used to investigate the morphology of the blend. Mechanical properties were evaluated using a Universal Testing Machine (UTM). The chitosan/collagen films were found to swell proportionally with time until it reaches equilibrium. FTIR spectroscopy indicated no chemical interaction between the components of the blends. DSC data indicated only one peak proving that these two materials are compatible at all proportions investigated. SEM micrographs also indicated good homogeneity between these two materials.
Biocompatible Materials/*analysis
;
Burns/physiopathology
;
Burns/*therapy
;
Chitosan/*analysis
;
Collagen Type I/*analysis
;
*Materials Testing
;
Microscopy, Electron, Scanning
;
*Occlusive Dressings
;
Regeneration/*physiology
;
Skin/*physiopathology
;
Spectroscopy, Fourier Transform Infrared
;
Tensile Strength