1.The study on the correlation of pulse wave velocity and ankle-brachial index to ischemic stroke in patients.
Hui LI ; Han WANG ; Yucai WANG ; Li RAO
Journal of Biomedical Engineering 2011;28(3):559-562
We measured the ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) and ABI in 97 ischemic stroke patients and 93 control subjects to investigate the relationship between baPWV, ABI and risk factors of ischemic stroke. The stroke patients were grouped according to the results of MRA and Carotid artery color Doppler ultrasound. The correlation of baPWV and ABI to the arteriosclerosis was discussed. There was a significant difference in the patients with hypertension, diabetes mellitus, baPWV and ABI between ischemic stroke patients and control subjects. baPWV was the most sensitive risk factor for ischemic stroke. ABI and diabetes mellitus were the relatively sensitive risk factors for ischemic stroke. baPWV were found to have a positive correlation with common carotid arteriosclerosis (gamma=0.215, P=0.048), while ABI had a negative correlation with intracranial arteriosclerosis (gamma=-0.237, P<0.05). BaPWV and ABI may closely relate to severity of ischemic stroke. Simple measurements of baPWV and ABI in patients could be a useful tool for evaluating the risk of ischemic stroke.
Aged
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Ankle
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blood supply
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Ankle Brachial Index
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Arteriosclerosis
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physiopathology
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Blood Flow Velocity
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Brachial Artery
;
physiopathology
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Brain
;
blood supply
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pathology
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Brain Ischemia
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complications
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Carotid Arteries
;
physiopathology
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Female
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Humans
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Male
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Middle Aged
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Pulsatile Flow
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Pulse
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Risk Factors
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Stroke
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diagnosis
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etiology
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physiopathology
2.Progression of Impending Central Retinal Vein Occlusion to the Ischemic Variant Following Intravitreal Bevacizumab.
Korean Journal of Ophthalmology 2010;24(3):179-181
A 60-year-old woman who had experienced two episodes of amaurosis fugax in her right eye presented with vision loss. Two weeks earlier, at a private clinic, she was diagnosed with impending central retinal vein occlusion (CRVO) of the right eye and received an intravitreal injection of bevacizumab. Two weeks after this injection she was diagnosed with ischemic CRVO. At 11-weeks post-presentation, extremely ischemic features were observed with fluorescein angiographic findings of severe vascular attenuation and extensive retinal capillary obliteration. At 22-weeks post-presentation she was diagnosed with neovascular glaucoma; she experienced no visual improvement over the following several months.
Antibodies, Monoclonal/*administration & dosage
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Disease Progression
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Female
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Fluorescein Angiography
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Glaucoma, Neovascular/complications
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Humans
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Injections, Intraocular
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Ischemia/diagnosis/*etiology/physiopathology
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Middle Aged
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Retinal Vein Occlusion/*complications/*drug therapy/physiopathology
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*Retinal Vessels
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Vascular Endothelial Growth Factor A/antagonists & inhibitors
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Visual Acuity/drug effects
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Vitreous Body
3.Successful Treatment of Ischemic Dysfunction of the Sinus Node with Thrombolytic Therapy: A Case Report.
Jong Seon PARK ; Dong Gu SHIN ; Young Jo KIM ; Gu Ru HONG ; Hyung Jun KIM ; Bong Sup SHIM
The Korean Journal of Internal Medicine 2006;21(4):283-286
We report on a case of ischemic dysfunction of the sinus node as a complication after percutaneous transluminal coronary angioplasty of the distal left circumflex artery. After local thrombolytic therapy in the sinus node artery, sinus node arterial flow was re-established and sinus node function normalized over the period of a week. Our experience suggests that immediate reperfusion of a totally occluded nodal artery can be re-established. Ischemic dysfunction of the sinus node, as a complication of angioplasty, is generally transient and requires a prolonged period for recovery. Therefore the decision to implant a permanent pacemaker should be delayed for at least one week after the ischemic insult.
Urinary Plasminogen Activator/administration & dosage/*therapeutic use
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Thrombolytic Therapy/*methods
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Sinoatrial Node/*physiopathology
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Myocardial Ischemia/*complications/radiography/therapy
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Middle Aged
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Male
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Infusions, Intravenous
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Humans
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Follow-Up Studies
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Fibrinolytic Agents/administration & dosage/*therapeutic use
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Electrocardiography
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Coronary Angiography
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Arrhythmia/diagnosis/*drug therapy/etiology
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Angioplasty, Transluminal, Percutaneous Coronary/adverse effects