1.Drug-Induced Hyponatremia.
Korean Journal of Nephrology 2009;28(1):88-92
No abstract available.
Hyponatremia
2.Neurocritical Care for Patients with Kidney Dysfunction
Journal of Neurocritical Care 2017;10(1):13-18
Kidney impairment due to acute kidney injury or chronic kidney disease is a potent risk factor for stroke which is a leading cause of morbidity and mortality worldwide. Patients with kidney impairment have various neurologic complications, including uremic encephalopathy, polyneuropathy, and cognitive impairment as well as higher rates of ischemic and hemorrhagic stroke and frequent seizures. Due to hypertension, coagulopathy, platelet dysfunction, and vascular disease, patients with kidney impairment are at high risk for types of catastrophic intracranial hemorrhages and strokes that typically lead to intracranial hypertension and cerebral herniation syndrome. Kidney impairment can alter drug pharmacokinetics and pharmacodynamics, and consequently patients with kidney impairment are at risk of experiencing adverse effects. Several central nervous system imaging modalities are not recommended in patients with compromised kidney function. Therefore, management of acute neurological conditions requires special attention in patients with kidney impairment. Given these common acute neurological conditions, physicians who care for patients with kidney impairment must be aware of evaluation and treatment of neurological diseases to achieve positive neurological outcomes.
Acute Kidney Injury
;
Blood Platelets
;
Brain Diseases
;
Central Nervous System
;
Cerebrovascular Disorders
;
Cognition Disorders
;
Humans
;
Hypertension
;
Intracranial Hemorrhages
;
Intracranial Hypertension
;
Kidney Diseases
;
Kidney
;
Mortality
;
Pharmacokinetics
;
Polyneuropathies
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Renal Insufficiency, Chronic
;
Risk Factors
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Seizures
;
Stroke
;
Vascular Diseases
3.Posterior Nutcracker Syndrome with Microscopic Hematuria
Jong Hoon PARK ; Na Mi LEE ; Jong Cheol JEONG ; Gyu Tae SHIN ; Heung Soo KIM ; Inwhee PARK
Korean Journal of Medicine 2019;94(2):221-224
Nutcracker syndrome (NCS) refers to left renal vein compression with impaired blood outflow. The etiology of NCS has been attributed to various anatomic anomalies. Posterior NCS is caused by compression of the retroaortic left renal vein between the aorta and spine. The classic symptoms of NCS include left flank pain with gross or microscopic hematuria. The frequency and severity of the syndrome vary from asymptomatic microhematuria to severe pelvic congestion. For this reason, diagnosis of NCS is difficult and often delayed. Here, we report a case of posterior NCS that was incidentally discovered.
Aorta
;
Diagnosis
;
Estrogens, Conjugated (USP)
;
Flank Pain
;
Hematuria
;
Renal Veins
;
Spine
4.Posterior Nutcracker Syndrome with Microscopic Hematuria
Jong Hoon PARK ; Na Mi LEE ; Jong Cheol JEONG ; Gyu Tae SHIN ; Heung Soo KIM ; Inwhee PARK
Korean Journal of Medicine 2019;94(2):221-224
Nutcracker syndrome (NCS) refers to left renal vein compression with impaired blood outflow. The etiology of NCS has been attributed to various anatomic anomalies. Posterior NCS is caused by compression of the retroaortic left renal vein between the aorta and spine. The classic symptoms of NCS include left flank pain with gross or microscopic hematuria. The frequency and severity of the syndrome vary from asymptomatic microhematuria to severe pelvic congestion. For this reason, diagnosis of NCS is difficult and often delayed. Here, we report a case of posterior NCS that was incidentally discovered.
5.Renal Failure with Branchio-Oto-Renal Syndrome.
Ji Won KIM ; Sunhong LEE ; Hyun Ee YIM ; Jong Cheol JEONG ; Gyu Tae SHIN ; Heungsoo KIM ; Inwhee PARK
Korean Journal of Medicine 2018;93(4):398-403
Branchio-oto-renal (BOR) syndrome is a rare autosomal dominant disorder that is characterized by preauricular pits, branchial fistula, branchial cyst, hearing impairment, and kidney anomalies. Hearing impairment is the single most common feature of BOR syndrome, affecting 89% of patients. Preauricular pits (77%), kidney anomalies (66%), branchial fistula (63%), external auditory canal anomalies (41%) are also common. For most patients, BOR syndrome does not affect life expectancy. The major life-threatening feature of this condition is kidney dysfunction, which occurs with about 6% of kidney anomalies. Therefore, once BOR syndrome is recognized in a patient, careful evaluation to detect renal anomalies and treatment of any kidney involvement are necessary. No case reports of BOR syndrome involving adult-onset end-stage kidney disease have been published in the Korean medical literature. We report a case of end-stage kidney disease in a 19-year-old male patient with BOR syndrome, together with a review of the pertinent literature.
Branchio-Oto-Renal Syndrome*
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Branchioma
;
Ear Canal
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Fistula
;
Hearing Loss
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Humans
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Kidney
;
Kidney Failure, Chronic
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Life Expectancy
;
Male
;
Renal Insufficiency*
;
Young Adult
6.Bilateral Emphysematous Pyelonephritis.
The Korean Journal of Internal Medicine 2012;27(3):366-366
No abstract available.
Anti-Bacterial Agents/therapeutic use
;
*Emphysema/diagnosis/microbiology/therapy
;
Escherichia coli/isolation & purification
;
*Escherichia coli Infections/diagnosis/microbiology/therapy
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Female
;
Humans
;
*Kidney/pathology/surgery
;
Middle Aged
;
Necrosis
;
Nephrectomy
;
*Pyelonephritis/diagnosis/microbiology/therapy
;
Renal Dialysis
;
Tomography, X-Ray Computed
;
Treatment Outcome
7.Mental illness in patients with end-stage kidney disease in South Korea: a nationwide cohort study
Min-Jeong LEE ; Eunyoung LEE ; Bumhee PARK ; Inwhee PARK
Kidney Research and Clinical Practice 2022;41(2):231-241
The limited literature on mental illness in end-stage kidney disease (ESKD) patients suggests that this disease is common and burdensome but underrecognized in clinical practice. This study aimed to analyze the prevalence of mental illness in ESKD patients. Methods: We assessed the prevalence and patterns of mental illnesses in a nationwide cohort of patients diagnosed with ESKD between January 1, 2008, and December 31, 2017. The risk of mental illness was evaluated using a multivariable Cox proportional hazards model. Results: A total of 70,079 patients met all study inclusion criteria. A total of 28.3% of patients had mental illness, and the specific distribution was as follows: depression, 16.8%; anxiety, 20.0%; somatoform/conversion disorder, 0.9%; stress reaction/adjustment disorder, 2.5%; and substance abuse disorder, 0.6%. The frequency of mental illness was highest in patients on hemodialysis (HD), followed by patients on peritoneal dialysis (PD) and kidney transplant (KT) patients. The peak rate of mental illness in HD and PD patients was reached 1 to 2 years after renal replacement therapy initiation, but the peak rate of most mental illnesses in KT patients occurred before surgery. The prevalence of depression was 2.19 times higher in HD patients and 1.97 times higher in PD patients than in KT patients. Conclusion: ESKD patients are at high risk of mental illness, and the prevalence of mental illness is highest in HD patients. Since the onset of mental illness occurs around the initiation of renal replacement therapy, clinicians need to pay attention to mental illness when treating ESKD patients.
8.Allogenic Peripheral Blood Stem Cell Transplant-Induced Membranous Glomerulonephropathy as Chronic Graft-Versus-Host Disease.
Jung Eun KIM ; Eun jung YOO ; Ah Reum KIM ; Jun Eun PARK ; Gyu Tae SHIN ; Heungsoo KIM ; Inwhee PARK
Korean Journal of Medicine 2017;92(6):541-545
Heavy proteinuria in the nephrotic range is an uncommon, often unrecognized manifestation of graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation. A few isolated case reports have been published in the Korean literature involving a small number of patients who developed membranous nephropathy as GVHD after peripheral blood stem cell transplantation (PBSCT). A 17-year-old female was diagnosed with non-Hodgkin's lymphoma. Following remission, she underwent allogeneic PBSCT. Shortly thereafter, she developed acute GVHD, which was managed by medical therapy with prednisolone and cyclosporine. Approximately 13 months following PBSCT, the patient developed proteinuria without peripheral edema. Pulsed steroid therapy was initiated three times, but her condition did not improve. Twenty months after PBSCT, she developed nephrotic range proteinuria. A renal biopsy was performed, and the diagnosis was histologically consistent with membranous nephropathy. Because the response to steroids was not satisfactory, the dose of cyclosporine was increased. Approximately 3 months after renal biopsy, the proteinuria disappeared. Given the recent increase in the incidence of GVHD-mediated renal disease, in particular, renal biopsy is indispensable to the diagnosis of nephropathy and to the prevention of disease progression.
Adolescent
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Biopsy
;
Cyclosporine
;
Diagnosis
;
Disease Progression
;
Edema
;
Female
;
Glomerulonephritis, Membranous*
;
Graft vs Host Disease*
;
Hematopoietic Stem Cell Transplantation
;
Humans
;
Incidence
;
Lymphoma, Non-Hodgkin
;
Peripheral Blood Stem Cell Transplantation
;
Prednisolone
;
Proteinuria
;
Stem Cells*
;
Steroids
9.Clinical Comparison of Automated Peritoneal Dialysis with Continuous Ambulatory Peritoneal Dialysis.
Jinhee CHO ; Sukyong YU ; Inwhee PARK ; Heungsoo KIM ; Gyu Tae SHIN
Korean Journal of Nephrology 2010;29(4):482-488
PURPOSE: Automated peritoneal dialysis (APD) is increasingly used due to freedom from daytime exchanges and flexibility of prescription. In this study, we compared APD with continuous ambulatory peritoneal dialysis (CAPD) to assess the influence of mode of PD on various measures of clinical performance. METHODS: We followed 26 APD patients prospectively over a 12-month period and compared them with 16 CAPD patients in whom examinations of dialysis dose and residual renal function (RRF) at least twice during the 1st one year after dialysis were done. Weekly Kt/V urea (Kt/V) and standard creatinine clearance (SCCr) of PD, and RRF (24hr urine creatinine clearance) were measured at 1st month, 6th month and 12th month after start of dialysis. In addition, serial biochemical tests were analyzed every three months during this period. RESULTS: No statistically significant differences in baseline characteristics, RRF, SCCr and Kt/V were observed between APD and CAPD patients. Serum concentrations of bicarbonate, hemoglobin, and calcium tended to be higher in the APD group and actually serum bicarbonate levels at 9 months, calcium levels at 12 months and hemoglobin levels at 6 and 9 months were significantly higher in APD patients (p<0.05). There was no significant difference in serum sodium concentrations and peritonitis rate between the two groups. CONCLUSION: No significant differences were observed between APD and CAPD in Kt/V, SCCr and RRF for one year after start of PD. APD, however, may be advantageous in improving several biochemical markers such as blood levels of hemoglobin, bicarbonate, and calcium compared to CAPD.
Biochemistry
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Biomarkers
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Calcium
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Creatinine
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Dialysis
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Diphosphonates
;
Freedom
;
Hemoglobins
;
Humans
;
Peritoneal Dialysis
;
Peritoneal Dialysis, Continuous Ambulatory
;
Peritonitis
;
Pliability
;
Prescriptions
;
Prospective Studies
;
Sodium
;
Urea
10.Concurrent Linear Immunoglobulin A Dermatosis, Hashimoto Thyroiditis, and Immunoglobulin A Nephropathy in an Adult.
Ji Young YANG ; Inwhee PARK ; Sue Kyung KIM
Annals of Dermatology 2017;29(2):226-228
No abstract available.
Adult*
;
Glomerulonephritis, IGA*
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Hashimoto Disease*
;
Humans
;
Immunoglobulin A*
;
Immunoglobulins*
;
Skin Diseases*