1.Ratio of visceral fat area to body fat mass (VBR) is a superior predictor of coronary heart disease.
Binbin ZHANG ; Jiangshan HE ; Pei GUO ; Jianxiong WANG ; Chunjun LI ; Li ZHANG ; Congfang GUO ; Yirui GUO ; Fenghua GUO ; Mianzhi ZHANG ; Minying ZHANG
Chinese Medical Journal 2023;136(19):2380-2382
2.Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study.
Katsuyasu KOUDA ; Yuki FUJITA ; Kumiko OHARA ; Takahiro TACHIKI ; Junko TAMAKI ; Akiko YURA ; Jong-Seong MOON ; Etsuko KAJITA ; Kazuhiro UENISHI ; Masayuki IKI
Environmental Health and Preventive Medicine 2021;26(1):35-35
BACKGROUND:
Body mass-independent parameters might be more appropriate for assessing cardiometabolic abnormalities than weight-dependent indices in Asians who have relatively high visceral adiposity but low body fat. Dual-energy X-ray absorptiometry (DXA)-measured trunk-to-peripheral fat ratio is one such body mass-independent index. However, there are no reports on relationships between DXA-measured regional fat ratio and cardiometabolic risk factors targeting elderly Asian men.
METHODS:
We analyzed cross-sectional data of 597 elderly men who participated in the baseline survey of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study, a community-based single-center prospective cohort study conducted in Japan. Whole-body fat and regional fat were measured with a DXA scanner. Trunk-to-appendicular fat ratio (TAR) was calculated as trunk fat divided by appendicular fat (sum of arm and leg fat), and trunk-to-leg fat ratio (TLR) as trunk fat divided by leg fat.
RESULTS:
Both TAR and TLR in the group of men who used ≥ 1 medication for hypertension, dyslipidemia, or diabetes ("user group"; N = 347) were significantly larger than those who did not use such medication ("non-user group"; N = 250) (P < 0.05). After adjusting for potential confounding factors including whole-body fat, both TAR and TLR were significantly associated with low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, fasting serum insulin, and the insulin resistance index in the non-user group and non-overweight men in the non-user group (N = 199).
CONCLUSION
The trunk-to-peripheral fat ratio was associated with cardiometabolic risk factors independently of whole-body fat mass. Parameters of the fat ratio may be useful for assessing cardiometabolic risk factors, particularly in underweight to normal-weight populations.
Absorptiometry, Photon
;
Adiposity/physiology*
;
Aged
;
Aged, 80 and over
;
Biomarkers/metabolism*
;
Cardiometabolic Risk Factors
;
Cross-Sectional Studies
;
Humans
;
Intra-Abdominal Fat/diagnostic imaging*
;
Japan
;
Male
;
Osteoporosis/etiology*
;
Prospective Studies
;
Risk Assessment
;
Risk Factors
;
Thorax/diagnostic imaging*