1.Changes of Detrusor Contractility and Growth Factors in Streptozotocin-induced.
Joon Chul KIM ; Seong Il SEO ; Yong Hyun PARK ; Tae Kon HWANG
Korean Journal of Urology 2000;41(5):615-621
No abstract available.
Intercellular Signaling Peptides and Proteins*
2.Growth Factors during Perinatal Life.
Journal of Korean Society of Pediatric Endocrinology 2004;9(2):113-121
No abstract available.
Intercellular Signaling Peptides and Proteins*
3.The Effect of Growth Factors and Surgical Precedures on Fibrovascular Ingrowth into anophthalmic Socket Implant of Porous Polyethylene.
Kyung In WOO ; Joon Mo KIM ; Hae Ran CHANG ; Myung Sook KIM ; Yoon Duck KIM ; Jae Heung LEE
Journal of the Korean Ophthalmological Society 2000;41(12):2725-2731
No Abstract Available.
Intercellular Signaling Peptides and Proteins*
;
Polyethylene*
4.Usefulness of insulin - like growth factors in predicting reduced bone mass in natural postmenopausal women.
Ki Bum AHN ; Jung Gu KIM ; Kwang Bum BAI ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 2000;43(10):1813-1821
No abstract available.
Female
;
Humans
;
Insulin*
;
Intercellular Signaling Peptides and Proteins*
6.EFFECT OF VARIOUS GROWTH FACTORS IN CULTURE OF EAR CHONDROCYTES OF RABBIT.
Sang Hoon HAN ; Jeong Hoon KANG ; Chang Gi SUNG ; Jae Dam LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):884-892
No abstract available.
Chondrocytes*
;
Ear*
;
Intercellular Signaling Peptides and Proteins*
8.Subepithelial connective tissue graft with and without the use of plasma rich in growth factors for treating root exposure.
Ardeshir LAFZI ; Masoumeh FARAMARZI ; Adileh SHIRMOHAMMADI ; Ahmad BEHROZIAN ; Atabak KASHEFIMEHR ; Ehsan KHASHABI
Journal of Periodontal & Implant Science 2012;42(6):196-203
PURPOSE: The aim of this study was to evaluate the clinical efficiency of the subepithelial connective tissue graft (SCTG) with and without plasma rich in growth factor (PRGF) in the treatment of gingival recessions. METHODS: Twenty bilateral buccal gingival Miller's Class I and II recessions were selected. Ten of the recessions were treated with SCTG and PRGF (test group). The rest ten of the recessions were treated with SCTG (control group). The clinical parameters including recession depth (RD), percentage of root coverage (RC), mucogingival junction (MGJ) position, clinical attachment level (CAL), and probing depth (PD) were measured at the baseline, and 1 and 3 months later. The data were analyzed using the Wilcoxon signed rank and Mann-Whitney U tests. RESULTS: After 3 months, both groups showed a significant improvement in all of the mentioned criteria except PD. Although the amount of improvement was better in the SCTG+PRGF group than the SCTG only group, this difference was not statistically significant. The mean RC was 70.85+/-12.57 in the test group and 75.83+/-24.68 in the control group. CONCLUSIONS: Both SCTG+PRGF and SCTG only result in favorable clinical outcomes, but the added benefit of PRGF is not evident.
Connective Tissue
;
Intercellular Signaling Peptides and Proteins
;
Plasma
;
Transplants
9.Observations on Some of the Mycelial Growth and Pigmentation Characteristics of Cordyceps militaris Isolates.
Bhushan SHRESTHA ; Won Ho LEE ; Sang Kuk HAN ; Jae Mo SUNG
Mycobiology 2006;34(2):83-91
Characteristic growth patterns of Cordyceps militaris isolates on various media, under varying light conditions and at varying incubation periods were examined. Light was found to be the most critical single factor in determining the density, texture, and pigmentation of the mycelial culture of the fungus. However, under the light condition, the degree of pigmentation and mycelial density were found to be affected by the incubation period and type of medium. Irrespective of the variations in medium type or incubation period, there was no pigmentation of the mycelium under dark condition. Radial growth of the mycelium was faster under dark incubation rather than under light incubation. Abundant mycelial density and darkest pigmentation of C. militaris isolates were produced in nutritionally rich media like SDAY, SMAY and CZYA, suggesting that these media may fulfill all the requirements for vegetative growth of the fungus. Growth characteristics of C. militaris isolates could be easily observed by the simple agar culture method, which would be useful to characterize the phenotypic characteristics of large number of pure cultures of the fungus under given conditions of growth factors such as medium, light and temperature.
Agar
;
Cordyceps*
;
Fungi
;
Intercellular Signaling Peptides and Proteins
;
Mycelium
;
Pigmentation*
10.The Effects of Heparin on Proliferation and Endothelin Production in Glomerular Mesangial Cells.
Dae Suk HAN ; Kyu Hun CHOI ; Shin Wook KANG ; Duk Hee KANG ; Ho Yung LEE
Korean Journal of Nephrology 1997;16(1):1-9
Glomerular mesangial cells have receptors to various growth factors and vasoactive peptides such as platelet-derived growth factor(PDGF), and endothelin(ET), which are important mediators for the progression of glomerular diseases. Heparin has been reported to have anti-proliferative effects in vascular smooth muscle cells and mesangial cells. Furthermore, the treatment with heparin suppresses the progression of experimental mesangioproliferative glomerulonephritis. The present study was carried out to further ascertain inhibitory effects of heparin and possible mechanisms of its action, particularly in relation to the effect on ET production of mesangial cells. The effect of heparin on PDGF-stimulated proliferation was assessed by [3H]thymidine uptake as well as the increase of number of cells, and ET production was evaluated in cultured rat mesangial cells. The results were as follows: 1) PDGF at a concentration of 10 ng/ml stimulated [3H]thymidine uptake significantly(mean+/-S.D., 512.0+/-38.6 cpm/well vs. 3300.4+/-432.5, p<0.05), and also increased the number of cells significantly, compared to control(23.0+/-3.5X10(3)/well vs. 66.5+/-8.9, p<0.05). 2) Heparin inhibited the PDGF(10ng/ml)-stimulated proliferation of mesangial cells in a dose-dependent manner(100microgram/ml, 3300.4+/-432.5cpm/well vs. 1452.5+/-264.7, 66.5+/-8.9 cpm/well vs. 20.0+/-6.5, p<0.05). 3) While N-desulfated heparin did not show the inhibitory effect on [3H]thymidine uptake, the potency of intact heparin(100microgram/ml) was 56.2+/-8.0% inhibition, which was similar to chondroitin sulfate(48.9+/-5.4%). N-desulfated N-acetylated heparin showed 25.7+/-9.7% inhibition. 4) PDGF stimulated the production of ET in a dose-dependent manner(25ng/ml, 4.2+/-0.7pg/ml/mg of protein vs 15.7+/-1.4, p<0.05). 5) Heparin inhibited the PDGF(25ng/ml)-stimulated ET production in a dose-dependent pattern(100microgram/ml, 12.6+/-3.5 vs. 2.5+/-1.1, p<0.05). From the above results, it is concluded that heparin has a significant inhibitory effect on proliferation and ET production in mesangial cells, and this anti-proliferative effect of heparin appears to be related to the structure of heparin, especially N-sulfation. In conclusion, heparin may reduce glomerular injury through these inhibitory effects on mesangial cells, but the further studies such as in vivo experiments considering the anticoagulation effect are needed.
Animals
;
Chondroitin
;
Endothelins*
;
Glomerulonephritis
;
Heparin*
;
Intercellular Signaling Peptides and Proteins
;
Mesangial Cells*
;
Muscle, Smooth, Vascular
;
Peptides
;
Rats