1.A Case of Hypersensitivity to Mosquito Bites without Peripheral Natural Killer Cell Lymphocytosis in a 6-Year-Old Korean Boy.
Han Su SEON ; Ji Hyeon ROH ; Seung Ho LEE ; Eun Kyeong KANG
Journal of Korean Medical Science 2013;28(1):164-166
Hypersensitivity to mosquito bites (HMB) is a rare disease characterized by intense skin reactions such as bulla and necrotic ulcerations at bite sites, accompanied by general symptoms such as high-grade fever and malaise occurred after mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer (NK) cell leukemia/lymphoma. We describe here a Korean child who presented with 3-yr history of HMB without natural killer cell lymphocytosis. He has been ill for 6 yr with HMB. Close observation and examination for the development of lymphoproliferative status or hematologic malignant disorders is needed.
Child
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Epstein-Barr Virus Infections/complications
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Humans
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Hypersensitivity/*diagnosis/etiology
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Insect Bites and Stings/*diagnosis/pathology
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Killer Cells, Natural/immunology
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Lymphocytosis/complications/pathology
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Male
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Republic of Korea
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Skin/pathology
2.Human Sting of Cephalonomia gallicola (Hymenoptera: Bethylidae) in Korea.
In Yong LEE ; Chang Seob SHIN ; Seobo SIM ; Jung Won PARK ; Tai Soon YONG
The Korean Journal of Parasitology 2014;52(6):681-684
Hymenoptera stings can cause serious injury to humans. We report the clinical findings of 6 cases of Hymenoptera stings. All patients developed painful erythematous papules at the sting sites and had a past history of parasitoid wasp sting. This is the first clinical report of the parasitoid wasp, Cephalonomia gallicola, causing human stings in Korea.
Adult
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Animals
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Child, Preschool
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Female
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Gram-Positive Bacteria
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Humans
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Hymenoptera/*growth & development
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Insect Bites and Stings/*diagnosis/*pathology
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Male
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Middle Aged
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Republic of Korea
3.A Case of Hypersensitivity to Mosquito Bite Associated with Epstein-Barr Viral Infection and Natural Killer Cell Lymphocytosis.
Eui Jung ROH ; Eun Hee CHUNG ; Young Pyo CHANG ; Na Hye MYOUNG ; Young Koo JEE ; Min SEO ; Jin Han KANG
Journal of Korean Medical Science 2010;25(2):321-323
Hypersensitivity to mosquito bites (HMB) is a disorder characterized by a necrotic skin reaction and generalized symptoms subsequent to mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer cell leukemia/lymphoma. We describe here a Korean child who had HMB associated with chronic EBV infection and natural killer cell lymphocytosis. A 5-yr-old boy was suffered from necrotic skin lesions on the right ear lobe. Type A EB virus was detected from hlood cells and bone marrow biospy recognized hemophagocyrosis.
Animals
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Child, Preschool
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Culicidae/*immunology
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Epstein-Barr Virus Infections/complications/*diagnosis
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Herpesvirus 4, Human/genetics/isolation & purification
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Humans
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Hypersensitivity/complications/*diagnosis
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Insect Bites and Stings/complications/*immunology
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Killer Cells, Natural/immunology/*pathology
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Lymphocytosis/complications/*diagnosis
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Male
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Polymerase Chain Reaction
4.Hypersensitivity to Mosquito Bites Associated with Natural Killer Cell-derived Large Granular Lymphocyte Lymphocytosis: A Case Report in Korea.
Joo Seop CHUNG ; Ho Jin SHIN ; Eun Yup LEE ; Goon Jae CHO
The Korean Journal of Internal Medicine 2003;18(1):50-52
Hypersensitivity to mosquito bites (HMB) is characterized by intense skin reactions at bite sites. The pathogenesis of HMB might be related to clonal lymphoproliferation of Epstein-Barr virus DNA-positive natural killer (NK) cells. We report the first case of HMB possibly associated with NK cell-derived large granular lymphocyte (NK-LGL) lymphocytosis in Korea.
Adult
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Animals
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Base Sequence
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*Culicidae
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Epstein-Barr Virus Infections/*complications/diagnosis
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Humans
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Hypersensitivity/*etiology/virology
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Insect Bites and Stings/*complications/immunology
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Killer Cells, Natural/*immunology/pathology
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Korea
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Lymphocytosis/*complications/pathology
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Male
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Molecular Sequence Data
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Polymerase Chain Reaction
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Prognosis
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Risk Assessment