Langerhans cell histiocytosis (LCH) refers a group of disorders of the reticuloendothelial system characterized by a proliferation of histiocytes, which includes eosinophilic granuloma, Lettere-Siwe diseases, and Hand-Schuler Christian disease. The clinical presentation of LCH depends on the site of involvement. It can range from multifocal lesions to a solitary lesion. Tissues characteristically involved in LCH are bone, skin, lung, liver, spleen, bone marrow, lymph nodes and the hypothalamic-pituitary region, although the involvement of other organs such as the bowel can occur. We experienced a case of external auditory canal stenosis in LCH of multiple organ involvement in a 28-year-old male, and report it with a review of the relevant literature.
Adult ; Bone Marrow ; Constriction, Pathologic ; Ear Canal ; Eosinophilic Granuloma ; Histiocytes ; Histiocytosis, Langerhans-Cell ; Humans ; Liver ; Lung ; Lymph Nodes ; Male ; Mononuclear Phagocyte System ; Skin ; Spleen ; Temporal Bone

Langerhans cell histiocytosis (LCH) refers a group of disorders of the reticuloendothelial system characterized by a proliferation of histiocytes, which includes eosinophilic granuloma, Lettere-Siwe diseases, and Hand-Schuler Christian disease. The clinical presentation of LCH depends on the site of involvement. It can range from multifocal lesions to a solitary lesion. Tissues characteristically involved in LCH are bone, skin, lung, liver, spleen, bone marrow, lymph nodes and the hypothalamic-pituitary region, although the involvement of other organs such as the bowel can occur. We experienced a case of external auditory canal stenosis in LCH of multiple organ involvement in a 28-year-old male, and report it with a review of the relevant literature.
Adult ; Bone Marrow ; Constriction, Pathologic ; Ear Canal ; Eosinophilic Granuloma ; Histiocytes ; Histiocytosis, Langerhans-Cell ; Humans ; Liver ; Lung ; Lymph Nodes ; Male ; Mononuclear Phagocyte System ; Skin ; Spleen ; Temporal Bone

Myeloid sarcoma is a rare solid, extramedullary tumor composed of immature granulocytes, occurring in a granulocytic leukemia. In rare cases, they can represent the initial manifestation of a relapsed form in patients with acute myelogenous leukemia in remission status. There have been only a few reports of myeloid sarcoma involving the temporal bone. We report a case of facial nerve paralysis caused by temporal bone myeloid sarcoma as the presenting symptom of leukemic relapse in a 27-year-old female, who was affected by acute myelogenous leukemia.
Adult ; Facial Nerve ; Female ; Granulocytes ; Humans ; Leukemia, Myeloid ; Leukemia, Myeloid, Acute ; Paralysis ; Recurrence ; Sarcoma, Myeloid ; Temporal Bone

One of the most common uses of osseointegration has been to supply patients with craniofacial defects with a bone-anchored epitheses (BAE). BAEs are usually used in the craniofacial defects such as congenital external ear anomalies or facial defects after cancer surgeries or trauma. We report a case of a 26 year-old woman with traumatic auricular amputation due to a traffic accident 4 years ago and a case of 23 year-old man with congenital ear deformity. They took osseointegrated implantations for an auricular prosthesis and are using it without complications. BAEs can be used with good functional and esthetic outcome for artificial auricular reconstruction.
Accidents, Traffic ; Amputation ; Congenital Abnormalities ; Ear ; Ear, External ; Female ; Humans ; Osseointegration ; Prostheses and Implants