Keratoacanthoma is a rapidly growing tumor that has the tendency of spontaneous involution but it may persist for some times, continue to enlarge and may become invasive and destructive. Many modalities are available for the treatment of keratoacanthoma. Although excisional surgery is the treatment of choice, this can result in functional and cosmetic defects when large or strategically located lesions are treated. An effective nonsurgical treatment would be desirable in such cases. We report two cases with unusually large or facial keratoacanthoma treated with intralesional methotrexate. One case showed complete resolution over 6 injections and the other after 2 injections. We suggest that intralesional injection of methotrexate is a simple, effective, safe and inexpensive method for the treatment of large keratoacanthoma.
Injections, Intralesional ; Keratoacanthoma* ; Methotrexate*

No abstract available.
Injections, Intralesional* ; Tuberculosis*

32.
Injections, Intralesional ; Lymphangioma* ; Picibanil* ; Sclerotherapy*

No abstract available.
Hemangioma* ; Injections, Intralesional* ; Propranolol ; Triamcinolone*

No abstract available.
Injections, Intralesional ; Isotretinoin ; Triamcinolone ; Triamcinolone Acetonide

Digital mucous cysts are observed frequently on the lateral or dorsal aspect of the digital fingers. Digital mucous cysts are prone to recur after simple excision, electrocoagulation, intralesional injection of corticosteroid and a variety of other therapeutic maneuvers. In this report, we describe one patient with digital mucous cyst who was successfully treated with intralesional injection of 1 mg/ml of minocycline hydrochloride without any sequelae.
Electrocoagulation ; Fingers ; Humans ; Injections, Intralesional ; Minocycline ; Sclerotherapy

Keratoacanthoma is a not uncommon skin tumor characterized by rapid growth of a smooth dome-shaped nodule with a central plug of keratin, usually followed by spontaneous involution. Because the tumor leaves a nunsightly scar, this is one of the reasons why these lesions should be treated. Excision is desirable if the diagnosis is in doubt. But surgical removal may be difficult, alternative treatment approaches should be considered. We report two cases of keratocathoma successfully treated by intralesional injection of 5-fluorouracil.
Cicatrix ; Diagnosis ; Fluorouracil* ; Injections, Intralesional* ; Keratoacanthoma* ; Skin

These are the first reported cases of granuloma faciale in two Koreans. Unilateral, slightly elevated violaceous plaque with illdefined margin on cheeck since 20 years ago was observed in 36 year old house-wife, and 40 year old male has had bilateral plaques on both cheek areas since 10 years ago, These plaques were showed the typical histological appearance of granuloma faciale respectively on both of two patients. Literature was briefly reviewed for the discussion of clinical and microseopic findings of this disease. Both patients were treated by intralesional injections and ointment of steroid with relative clinical improvements.
Adult ; Cheek ; Granuloma* ; Humans ; Injections, Intralesional ; Male

A typical case of lichen amyloidosis is reported. This case is considered to be the first one in Korea. Intralesional injection of prednisolone proved to be effective in this case. The etiologic and therapeutic aspects of this disease are discussed.
Amyloidosis* ; Injections, Intralesional ; Korea ; Lichens* ; Prednisolone

Keratoacanthoma is a rapidly growing, usually self-limited, hnil n tumor that has a striking rescmblance clinically ancl histologically to squamous cell carcinoma. Although thc keratoacanthorna is involuted spontaneously, then are several reasons why these lesions should treated. Treatment may hasten resolution, prevent extensive destruction of normal tissue, and improve she overall cosmetic result, and there are norabsolutely reliable diagnostic critcria to differcntiate these lesions from squamous cell carcinom complete excision is currently the choice of treatment or the majority of solitary keratoacanthims. However, this can lead to significant cosmetic or functional dcfects particularly in lesions located on intricate areas of thc face. Effective nonsurgical mclalities are rcquirced in such cases. Herein we report three cases of keratoacanthoma successfully reited by intralesional injection of 5-fluorouracil, and suggest that intralesional injection of 5-fluroiracil is a effective, safead convenient method of treatment for the multiplc keratoacahtnom and solitary lesions which are difficult to remove surgically.
Carcinoma, Squamous Cell ; Dronabinol ; Fluorouracil* ; Injections, Intralesional* ; Keratoacanthoma* ; Strikes, Employee