2.Progress in research of influenza vaccination in pregnant women.
Si Meng FAN ; Xiao Kun YANG ; Hong Ting ZHAO ; Ying QIN ; Jian Dong ZHENG ; Zhi Bin PENG ; Yan Ping ZHANG ; Zi Jian FENG
Chinese Journal of Epidemiology 2023;44(7):1157-1162
Influenza is an acute respiratory infectious disease caused by influenza virus. Pregnancy is associated with physiologic and immunological changes that may increase the risk for influenza virus infection and influenza-related complications. Influenza vaccination is the most effective way to prevent influenza virus infection. WHO and many countries have classified pregnant women as a priority population for influenza vaccination, however, there are still many challenges for promoting influenza vaccination in pregnant women in China, influenza vaccination coverage in pregnant women remains low and some influenza vaccine package inserts list pregnancy as an absolute contraindication. In this paper, we summarize the research progress in the effects of influenza infection and influenza vaccination during pregnancy both at home and abroad, then discuss the strategies to promote influenza vaccination in pregnancy for the purpose of providing reference for the related research and policy development in China.
Pregnancy
;
Female
;
Humans
;
Pregnant Women
;
Influenza, Human/epidemiology*
;
Pregnancy Complications, Infectious/epidemiology*
;
Influenza Vaccines
;
Vaccination
;
Orthomyxoviridae
5.From H1N1 to 2019-nCoV, what do we learn?
Gui-E LIU ; Yuan TIAN ; Wen-Jun ZHAO ; Shuang-Ming SONG ; Lei LI
Chinese Journal of Traumatology 2020;23(4):187-189
The COVID-19 pandemic is still raging across the world. Everyday thousands of infected people lost their lives. What is worse, there is no specific medicine and we do not know when the end of the pandemic will come. The nearest global pandemic is the 1918 influenza, which caused about 50 million deaths and partly terminate the World War Ⅰ. We believe that no matter the virus H1N1 for the 1918 influenza or 2019-nCoV for COVID-19, they are essentially the same and the final cause of death is sepsis. The definition and diagnostic/management criteria of sepsis have been modified several times but the mortality rate has not been improved until date. Over decades, researchers focus either on the immunosuppression or on the excessive inflammatory response following trauma or body exposure to harmful stimuli. But the immune response is very complex with various regulating factors involved in, such as neurotransmitter, endocrine hormone, etc. Sepsis is not a kind of disease, instead a misbalance of the body following infection, trauma or other harmful stimulation. Therefore we should re-think sepsis comprehensively with the concept of systemic biology, i.e. inflammationomics.
Betacoronavirus
;
Coronavirus Infections
;
complications
;
epidemiology
;
immunology
;
Humans
;
Immune Tolerance
;
Inflammation
;
complications
;
Influenza A Virus, H1N1 Subtype
;
Influenza, Human
;
complications
;
epidemiology
;
immunology
;
Pandemics
;
Pneumonia, Viral
;
complications
;
epidemiology
;
immunology
;
Sepsis
;
etiology
7.Follow-up Aspects of Influenza A (H1N1) Virus-Associated Pneumonia: the Role of High-Resolution Computed Tomography in the Evaluation of the Recovery Phase.
Edson MARCHIORI ; Glaucia ZANETTI ; Claudia Mauro MANO ; Bruno HOCHHEGGER ; Klaus Loureiro IRION
Korean Journal of Radiology 2010;11(5):587-587
10.Severe influenza A (H1N1) in late pregnancy: a case report.
Ruiling ZHANG ; Jinxi YUE ; Weihua ZHU ; Ouya LIU ; Ling DU ; Qingqing HUANG ; Runmei MA ; Linjun WAN
Chinese Critical Care Medicine 2019;31(12):1545-1546
Pregnancy has increased susceptibility to H1N1 influenza virus infection. Maternal influenza infection is associated with increased risk of morbidity and mortality. A case of influenza A (H1N1) during late pregnancy (pregnancy 1, birth 0, pregnancy 30+2 weeks) was admitted to the Second Affiliated Hospital of Kunming Medical University on December 16th, 2018. The patient was set on mechanical ventilation with a FiO2 of 1.0, a positive end-expiratory pressure (PEEP) of 15 cmH2O (1 cmH2O = 0.098 kPa), and a tidal volume of 4-6 mL/kg (ideal body weight). However the pulse oxygen saturation (SpO2) could only be maintained at about 0.85. The disease was controlled by the treatments of anti-infection, mechanical ventilation, immune therapy, nutritional support, preventive anticoagulant treatment by heparin sodium, adequate negative fluid balance, and other organ support therapy. This article introduced the treatment process of the patient in detail, and provided experience for clinical treatment.
Female
;
Humans
;
Influenza A Virus, H1N1 Subtype
;
Influenza, Human
;
Positive-Pressure Respiration
;
Pregnancy
;
Pregnancy Complications
;
Respiratory Distress Syndrome
;
Tidal Volume