No abstract available.
Industrial Development

Since microdroplets are able to be generated rapidly in large amount and each droplet can be well controlled as an independent micro-cultivator, droplet microfluidic technology can be potentially used in the culture of microorganisms, and provide the microbial culture with high throughput manner. But its application mostly stays in the laboratory-level building and using for scientific research, and the wide use of droplet microfluidics in microbial technology has been limited by the key problems that the operation for microdroplets needs high technical requirements with wide affecting factors and the difficulties in integration of automatic microdroplet instrumentation. In this study, by realizing and integrating the complicated operations of droplet generation, cultivation, detection, splitting, fusion and sorting, we design a miniaturized, fully automated and high-throughput microbial microdroplet culture system (MMC). The MMC can be widely used in microbial growth curve test, laboratory adaptive evolution, single factor and multi-level analysis of microbial culture, metabolite detection and so on, and provide a powerful instrument platform for customized microbial evolution and screening aiming at efficient strain engineering.
Industrial Development ; Microfluidics

BACKGROUND AND OBJECTIVE: Road safety in the Philippines has been increasingly significant with the increasing level of industrialization and urbanization over the last decade. The main objective of the study was to determine the road safety performance for Metro Manila by computing for an index based on data and variables of road traffic over the past years.

METHODOLOGY: The variables for index calculation included speed, alcohol, infrastructure, vehicle defect, and other unsafe driver behavior were drawn from the Metro Manila Development (MMDA) database complemented with literature review from several sources. Equal Weighting method was utilized, as this is the simplest, yet, least biased measurement suitable for the data at hand.

RESULTS AND CONCLUSION: The Road Safety Performance Index for Metro Manila remains more or less constant over a five-year period, increasing and decreasing from 0.45 to 0.59 which means that Metropolitan Manila has fared poorly in all indicators. Metro Manila has a poor road safety performance as evidenced by the road safety index. There is a need to improve on all components of road safety identified in this study for the safety of road users. 

User package program run on PC was developed for clinical spirometric test, which enabled to perform popular FVC, SVC, and MVV test items in a very convenient manner. In addition, a program module for research was implemented to study breathing pattern of a patient. The program written in C language was designed to run on Windows OS, and consisted of patient information management, test procedure control, results print out, and accumulation of parameter values in a customized data base which made possible future clinical research and quality assurance. When engaged with the previously developed respiratory air flow measurement unit, the system resulted in an accurate enough performance in that FVC data showed a high correlation coefficient of higher than 0.98 with an imported system. The technician tried the present system under clinical environment and judged the convenient utility to be satisfactory. Therefore, industrialization effort is being currently made and expected to be successful.
Humans ; Information Management ; Respiration ; Spirometry ; Industrial Development

Appropriate producing areas can guarantee the quality of Tibetan medicine, but research on the suitable ecological factors and suitable producing areas of Tibetan medicinal plants is scarce. This paper used the Geographic Information System for Global Medicinal Plants(GMPGIS) to analyze the ecological suitability of Tibetan medicinal plants nationwide. For the first time, the range of ecological factors and main soil types of Tibetan medicinal plants were extracted, such as the average annual temperature-19.4-24.2 ℃, annual average precipitation 17-4 088 mm, annual average sunshine 124.2-171.6 W·m~(-2). The main soil types were black calcareous soil, thin layer soil, chestnut soil and so on. Based on 337 sampling points, the largest ecological similarity area of Tibetan medicine across the country was obtained through ecological similarity analysis. In addition to Tibet and Qinghai provinces and Tibetan Autonomous Prefectures in Sichuan, Gansu, and Yunnan provinces, Jiuquan city and Linxia county in Gansu province, Panzhihua and Ya'an in Sichuan province, and Xinjiang, Inner Mongolia, and Shanxi provinces also had larger suitable cultivation areas. In addition, by analyzing the current situation of Tibetan medicine industry, the research pointed out that there were some problems such as unreasonable development and utilization of resources, lack of standards and norms, weak basic research and imperfect industrial system, and made corresponding countermeasures for sustainable development of resources, formulation of standards and specifications, promotion of medicine through science and technology, expansion of domestic and foreign markets, etc. This study provided the basis for guiding the rational layout of production bases, introduction and breeding of plant Tibetan medicine nationwide, laying the foundation for the scientific and standardized production of high-quality Tibetan medicine, clarifying the development direction of Tibetan medicine industry, and providing ideas for the development strategy of Tibetan medicine and other national medicine industry.
China ; Industrial Development ; Medicine, Tibetan Traditional ; Soil ; Tibet

Chinese medicine (CM) develops with the survival, reproduction, growth, and progressing of the Chinese nation. Scientific technologies not only promote continual progressing of human societies, but also provide new ideas and methods for the development of CM. In recent years, great changes have taken place in CM complying with developing modern scientific technologies, mainly manifested in the depth of CM theories at molecular levels, the combination of syndrome differentiation and disease identification, continuous innovation and development of clinical diagnosis and treatment techniques, diversified dosages of Chinese materia medica, the academic tendency of education patterns, occupational refinement, diversified medical practice modes, and so on.
Humans ; Industrial Development ; Materia Medica ; Medicine, Chinese Traditional ; trends ; Reproduction

OBJECTIVE: The aim of the present study is to estimate the incidence trend of head injury and the mortality based on traffic accident statistics and to investigate the impacts of rapid industrialization and economic growth on epidemiology of head injury in Korea over the period 1970-2012 including both pre-industrialized and post-industrialized stages. METHODS: We collected data of head injury estimated from traffic accident statistics and seven hospital based reports to see incidence trends between 1970 and 2012. We also investigated the population structure and Gross National Income (GNI) per capita of Korea over the same period. The age specific data were investigated from 1992 to 2012. RESULTS: The incidence of head injury gradually rose in the 1970s and the 1980s but stabilized until the 1990s with transient rise and then started to decline slowly in the 2000s. The mortality grew until 1991 but gradually declined ever since. However, the old age groups showed rather slight increase in both rates. The degree of decrease in the mortality has been more rapid than the incidence on head injury. CONCLUSION: In Korea during the low income stage, rapid industrialization cause considerable increase in the mortality and the incidence of head injury. During the high income stage, the incidence of head injury gradually declined and the mortality dropped more rapidly than the incidence due to preventive measures and satisfactory medical care. Nevertheless, the old age groups revealed rather slight increase in both rates owing to the large population structure and the declining birth rate.
Accidents, Traffic* ; Birth Rate ; Craniocerebral Trauma* ; Economic Development ; Epidemiology ; Head* ; Humans ; Incidence ; Korea* ; Mortality ; Industrial Development

Due to rapid industrialization and economic development, the occupational diseases have appeared as one of the social problems in Korea. Up until now little has been known about the prevalence rate, predisposing factor and symptomatology the occupational disease due to localized vibration in Korea. The researcher intends to investigate the prevalence rate and affecting factors of the occupational disease due to localized vibration among rock-drillers in the anthracite mines. A total of 135 rock-drillers were interviewed and examined from May 15th to 31th, 1980. The results were revealed as follows; 1. The prevalence rate of the vibration syndrome among rock-drillers was 12.6%. 2. The latent period of the vibration syndrome was 6.8% years. 3. The prevalence rate of the vibration syndrome was not significantly different between smokers and non-smokers. 4. With the increase of total vibration exposure time, the prevalence rate of the vibration syndrome increased also. 5. The average vibration sensation threshold was high (6.4dB) in stage 1 of the vibration syndrome and low (-0.6dB) in stage 0. 6. The average pain sensation threshold was high (4.4g) in stage 1 of the vibration syndrome and low (2.5g) in stage 0.
Causality ; Coal* ; Economic Development ; Korea ; Mining* ; Occupational Diseases ; Prevalence* ; Sensation ; Social Problems ; Vibration* ; Industrial Development

Due to rapid industrialization and economic development since 1970's, Seoul has become known as one of the most heavily polluted cities in the world. This is especially because of its air pollution. This study was conducted to characterize the cancer risk from organic pollutants in the suspended particulates of Seoul. Extractable organic matter(EOM)and PAHs in Shinchon, a major traffic area, were measured monthly in two periods of Aug. 1987-Sep. 1988, and Sep. 1990-Aug. 1991. While the differences both of EOM and benzo(a)pyrene concentrations between these two periods were not significant(P>0.05), the differences between heating and non-heating seasons were significant(P<0.01). The estimated mean concentrations of EOM and benzo(a)pyrene in fine particles in non-heating season were 3.98 microgram/m3 and 0.51ng/m3 respectively, and in heating season were 6.75 microgram/m3 and 2.96 ng/m3 respectively, in these two periods combined. The calculated risk from EOM was compared with that from benzo(a)pyrene and also these values were compared with the level of acceptable risk.
Air Pollution ; Benzo(a)pyrene ; Economic Development ; Heating ; Hot Temperature ; Seasons ; Seoul* ; Industrial Development

Incidences of blowout fractures have increased due to rapid industrialization and rise in violent crimes. However, there have been few studies on the proper follow-up guidelines or protocol after reduction of the orbital wall for patients working in a high atmospheric pressure environment. We have experienced a pilot with an orbital medial wall fracture who underwent reduction through an endoscopic approach. The patient underwent the Valsalva maneuver and scan of paranasal sinuses 8 weeks after reduction. Emphysema did not occur in the orbit even after the Valsalva maneuver and he was able to return to his workplace without any complications. We report this case with a brief review of the literature.
Atmospheric Pressure ; Crime ; Emphysema ; Follow-Up Studies ; Humans ; Incidence ; Orbit ; Paranasal Sinuses ; Valsalva Maneuver ; Industrial Development