In recent years, the IVD industry has developed rapidly based on the increasing market demand, and plays an important role in disease prevention, clinical diagnosis, health monitoring and guiding treatment. Therefore, followed quality and safety issues are highly concerned. The unique advantages of blockchain technology, decentralization, distrust and non-tampering, can write into trusted node data in every link covering production, circulation and usage of IVD reagents, and establish a distributed ledger with full backup, which makes the anti-conterfeiting and traceability for IVD reagents possible. We discuss whole process intelligent tracing system for IVD reagents based on blockchain technology. Through the strong mechanism of pre-supervision and post-punishment, the source of reagents can be traced, quality and responsibility can be investigated, and the medical inspection quality and diagnostic safety can be guarded.
Blockchain ; Indicators and Reagents ; Reagent Kits, Diagnostic ; Technology

From the perspective of technical review, this paper made statistics on the supplement contents of
Chemistry, Clinical/standards* ; China ; Indicators and Reagents ; Reagent Kits, Diagnostic/standards*

Clinical trial is an important step of in vitro diagnostic reagents research and development. Based on the Guiding Principles and the key points of inspect on the spot, combined with the actual work experience, the article focuses on the prominent problems in the whole process of in vitro diagnostic reagent clinical trials. It is helpful to improve the level of hospital drug clinical trial centre and the quality of in vitro diagnostic reagent clinical trials by analyzing the issues.
Clinical Trials as Topic ; Indicators and Reagents/administration & dosage* ; Reagent Kits, Diagnostic

No abstract available.
Indicators and Reagents*

No abstract available.
Indicators and Reagents*

In this paper, some significant problems, which were found frequently in the products of autoimmune
Indicators and Reagents

Treatment of rabbits, exposed to mix of yperite and lewisite with unithiol and naturenze showed that unithol reduced concentration of SGOT (serum glutamat-oxaloacetat-transaminase), SGPT (serum glutamat-pyruvat-transaminase), urea and creatinine in serum but concentration of these components was still high. Using unithiol in combination with naturenze for treatment, concentration of SGOT, SGPT, urea and creatinine was decreased lower than treatment of single unithiol.
Unithiol ; Toxicity ; Indicators and Reagents

Concentration of SGOT, SGPT, ure and creatinine was increased in serum of rabbits, exposed to diclodietylsulfid and clovinyldiclorasin. We realized that there were synergic effects between diclodietylsulfid and clovinyldiclorasin, caused increase of ure and creatinie in rabbits higher than effect of single agent. Concentration of glucose was increased at the third day and decreased at the 7th day in rabbits exposed to mix of clovinyldiclorasin and diclodietylsulfid.
Indicators and Reagents ; Toxicity

A study on the determination of level of indicators of platelet and their correlation in normal people and patients has shown that the platelet (PLT), mean platelet volume (MPV), plateleterit (PCT) and platelet distribution width (PDW) were determined which used as reference indicators. There were some differences of indicators of platelet between men and women. If patients had low platelet, they would have big MPV and reversely. When excessive increased or reduced platelet comparing with normal range, the PDW will be bigger which indicated that the unequal range of platelet size.
Blood Platelets ; Indicators and Reagents

We found that the number of institutions made use of the undocumented in vitro diagnostic reagent in the survey. The phenomenon poses some risks and problems. In use this paper, we analyzed the situation and the reasons for the use of the undocumented in vitro diagnostic reagents, and put forward the corresponding measures.
Humans ; Indicators and Reagents ; standards