No abstract available.
Tendon Injuries* ; Tendons*

No Abstracts Available.
Bronchoscopy*

No abstract available.
Rhinitis*

PURPOSE: The relationship between altered HLA expressions and cervical carcinogenesis is not fully elucidated. MATERIALS AND METHODS: The histological evaluation comprised of 21 microinvasive squamous cell carcinoma (SCC), 26 invasive SCC, 3 microinvasive adenocarcinoma and 9 invasive adeno carcinoma of cervix. We used monoclonal antibodys (mAbs) to HLA class I beta2-microglobulin (L368), HLA class I B/C heavy chains (HC-10) and HLA class II heavy chain (LG II-612.14). RESULTS: In tissues from microinvasive SCC, the expressions of B/C heavy chains and class II heavy chain were significantly decreased. The expressions of beta2-microglobulin, B/C chains, and class II heavy chain in SCC were all significantly decreased. Especially, in the metastatic tissue from the same patient, the expressions of beta2-microglobulin and B/C chains showed to be somewhat decreased compared to those in primary tumor tissues, and the expression of class II heavy chain was decreased further than that in primary lesion. In primary invasive adenocarcinoma, the expression of B/C chains was significantly decreased. CONCLUSION: These results suggest that alterations of HLA class I and II expressions seem to occur at a particular step in tumor development and depend on tissue types: when the tumor becomes invasive and starts to metastasize.
Adenocarcinoma ; Carcinogenesis ; Carcinoma, Squamous Cell ; Cervix Uteri ; Female ; Humans ; Uterine Cervical Neoplasms

No abstract available.
Foodborne Diseases*

The mechanism of serotonin(5-HT) induced contraction and Ca++ mobilization was investigated in right cut from rat aorta. Since it is known that 5-HT can interact with alpha-adrenoceptors in addition to a specific action on 5-HT receptors, the effects alpha-adrenoceptors antagonists on these contractile responses to 5-HT were investigated. The results are as follows : 1) 5-HT produced a strong transient contraction and a concentration dependent contraction. 2) The contractile tension to 5-HT increased with extracellular Ca++ concentration (0.1-5mM). 3) The response produced by rings exposed to Ca++-free PSS was significantly weaker than that produced by rings exposed to calcium containing PSS. When rings of aorta that had been stimulated with 5-HT once for 30 min in Ca++-free TBT were washed 4 times for at least; 20 min in zero Ca++PSS to remove 5-HT, than reexposed to 5-HT in Ca++-free TBT, a phasic contraction was not seen during the second stimulation with 5-HT. 4) The contractile response of 5-HT was inhibited by alpha-adrenergic receptor blocker, phenoxybenzamine and phentolamine. Phentolamine(10(-8)M) antagonized response to high concentrations of 5-HT but responses to low concentrations of 5-HT were not antagonized. 5) The contraction induced by 5-HT in Ca++-free PSS was investigated with phentolamin, methysergide. It was blocked by methysergide but not blocked by phentolamine. 6) These results suggest that 5-HT -induced contraction is the effect of both transmembrane Ca++ influx and the mobilization of intracellular Ca++. Low concentration of 5-HT act on specific 5-HT receptors but high concentration of 5-HT also act on alpha-adreno-receptors.
Animals ; Aorta* ; Calcium ; Methysergide ; Phenoxybenzamine ; Phentolamine ; Rats* ; Receptors, Adrenergic ; Receptors, Serotonin ; Serotonin

No abstract available.
Severe Acute Respiratory Syndrome*

No abstract available.
Hypothermia*

No abstract available.
Critical Care ; Intensive Care Units

The isoimmune hemolytic disease of newborn due to the minor blood groups is characterized by the progressive neonatal hyperbilirubinemia and anemia. This is caused by the lgG antibody transmitted from the mother to the fetus across the placenta. ABO and Rho(D) incompatability have been the most common antibody responsible for hemolytic disease of newborn. But recently the incidence of the Rho(D) incompatability is decreased due to the prophylaxis of anti-D immunoglobulin for the Rh negative mother and that of the incompataibility of minor blood group seems to be increased. This report presents the clinical and hematologic features of four cases of hemolytic diseases of newborn due to minor blood group isoimmunization who were admitted to the Dong-guk University Kyung-ju Hospital. The following results were obtained; 1) Neontal hyperbilirubinemia was observed within 48 hours after birth in all cases of patients and disappeared with the treatment of exchange transfusion and phototherapy. 2) Total bilirubin levels were 6.7-24.8 mg/dl. 3) Direct Coombs' test was positive in all cases of patients and indirect Coombs' test was positive except case 3. Direct Coombs' test was negative and indirect Coombs' test was positive in all mothers. 4) There was no evidence of ABO or Rh(D) incompatibility in all cases of patients. Case 1, 2 and 4 had the hemolytic diseases of newborn due to anti-E isoimmunization anti-E, but case 3 had the hemolytic diseases of newborn due to anti-C isoimmunization. 5) According to the reports which was published to date, 23 cases of the hemolytic diseases of newborn due to minor blood group isoimmunization were revealed; 14 anti-E, 4 anti-c, 1 anthE or c, 1 anti-C, 1 anti-e, 1 anti-M, and 1 anti-Kidd. Therefore we can easily conclude that anti-E is the most common cause of hemolytic diseases of newborn due to minor blood group isoimmunization in Korea. So, we report this case with the brief review of relevant literatures.
Anemia ; Bilirubin ; Blood Group Antigens ; Coombs Test ; Erythroblastosis, Fetal ; Fetus ; Gyeongsangbuk-do ; Humans ; Hyperbilirubinemia ; Hyperbilirubinemia, Neonatal ; Immunoglobulins ; Incidence ; Infant, Newborn ; Korea ; Mothers ; Parturition ; Phototherapy ; Placenta