We report the FDG PET findings in a patient with Marchiafava-Bignami disease (MBD) in whom there was diffusely reduced metabolism in the whole brain cortex and strongly decreased metabolism in the thalami. The use of FDG PET helps provide an understanding of the neurologic manifestations and prognosis of MBD.
Alcoholism ; Brain ; Humans ; Marchiafava-Bignami Disease* ; Metabolism ; Neurologic Manifestations ; Prognosis

In the 21st century, the number of elderly population will reach 10% of Korean's total population, As the elderly population are increasing, the anticipation of the elderly with chronic health problem are also increased. They feel social isolation, alienation because of pain, and psychological flinching such as depression, but they can not control appropriately their chronic pain. Therefore, this study is an attempt to expose a group reminiscence therapy effect to decrease pain and depression, increasing self-esteem of the elderly as effective therapeutic nursing intervention This study is conductcd for 5 weeks from July 28 to August 31, 1997. The Subjects of this study consisted of 33 the elderly women having ronic pain. 17 of 33 residents S nursing home were ontrol group in C city. 16 of 33 resident E nursin home were experimental group in M city. The study design was a nnneqi.uivalent nontrol group with a pretest-posttest design. As for the tool for this study, Visual An logue Scale and Discriptive rating Scale were u ed to measure the pain, Zung's Depression Status nventory(DSI) which was translated by Yang S k Ha was used to measure the depression, and self-esteem scale which was translated by Byung Jae Jeon was used Lo measure self-esteem. As for the process of the study, demo raphic variables, pain, depression, self-esteem were tested with both the experimental and control grou prior to the group reminiscence. The ezperimental group was divided into 3 subgroup and a total of 4 ession of the group reminiscence therapy was performed to the experimental group for an hour at a time once a week from the first to the fourth week. Analysis of this study was computerized by using SPSS/PC. and the homogeneity which may be affected by various bariables was verifie with Chi-square and t-test, the reliablity of th tools with Cronbach's alpha, the comparison of pre and post-test with t-test in the Pain, Depression, and Self-Esteem among the experimental group and control group. The Pearson Corelation Coefficient was for analysis the relation of the Pain, Depression and Self-esteem. The results of the study can be summarized as follows ; 1. The first hypothesis, the degree of pain will be decreased on the experimental group which performed group reminiscence therapy than that of control group, was supported. VAS(t = -2.35, p=.025), DRS(t= -2.11, p=O.43). 2. The second hypothesis, the degree of depression status of the experimental group which has perfomed group reminiscence therapy will be reduced than control group was supported(t= -2.53, p= .017). 3. The third hypothesis, self-esteem of the experiinental group which has performed group reminiscence therapy will be increased than that of control group was not supported(t=1.34, p= .191). 4. The fourth hypothesis, the correlation with pain, depression, self-esteem was to appeared highly. The significance of this study through the above results shows that the Group Reminiscence Therapy is an effective nursing intervention for the elderly with chronic pain and depression.
Aged* ; Chronic Pain* ; Depression* ; Emigrants and Immigrants ; Female ; Humans ; Nursing ; Nursing Homes ; Social Isolation

OBJECTIVE: No medication currently available for the treatment of rheumatoid arthritis is universally effective, and all can produce adverse effects. It is well known that the Acanthopanax koreanum extract has an anti-inflammatory action without any adverse effects reported. We conducted this study whether the Acanthopanax koreanum extract has a preventive and/or regressive effect of collagen induced arthritis in DBA/1J mice. METHODS: Three groups of BDA/1J mice were immunized by intradermal injection of 5ma/ka bovine type lI collagen with complete Freund s adjuvant. Group received 20ma/ka of Acanthopanax koreanum extract orally twice weekly and group K received 1ma/ka dexamethasone intraperitoneally twice weekly. Group ll and lll were divided into two subgroups respectively(Group Il-A, E-B, lll-A and Ill-B). Subgroup A is prevention group(Drugs were started to be given 3 weeks after immunization) and subgroup B is suppression group(Drugs were started to be given 6 weeks after immunization when CIA had been developed already). Group I received no treatment. The prevalence of arthritis were assessed twice weekly. Serum anti-collagen antibody and splenic mononuclear cell stimulation indices (SI) to collagen were measured. Serum tumor necrosis factor-a and interleukin-10 levels were also measured by ELISA. RESULT: Collagen induced arthritis(CIA) started to develop 4 weeks after collagen injections. In Acanthopanax koreanum extract treated group, CIA induction seemed not to be inhibited, but questionably partial supressive effect of arthritis were observed at 10 weeks after collagen injection. In dexamethasone treated group, both of prevention and suppression of CIA could be observed. Levels of anti-collagen antibodies were reduced in dexamethasone treated group, but not in the Acanthopanax koreanum extract treated group. No significant differences of splenic mononuclear cell SI among the groups was observed. There were no significant differences in the levels of serum tumor necrosis factor-a and interleukin-10 among the groups. CONCLUSIONS: These findings showed that the Acanthopanax koreanum extract does not have a definite effect on induction or supression of CIA.
Eleutherococcus* ; Animals ; Antibodies ; Arthritis* ; Arthritis, Rheumatoid ; Collagen* ; Dexamethasone ; Enzyme-Linked Immunosorbent Assay ; Immunization ; Injections, Intradermal ; Interleukin-10 ; Mice* ; Necrosis ; Prevalence

No abstract available.
Antibodies, Monoclonal*

No abstract available.

No abstract available.
Vertigo*

Coronary atherosclerosis begins with the impairment of endothelial function of anti-thrombosis, vasorelaxation, anti-proliferation, and anti-atherosclerosis. Endothelial dysfuction is induced not only by bio-chemical factors such as hypercholesterolemia, smoking, hypertension, and diabetes mellitus, but also by bio-mechanical factors, such as disturbance of laminar flow of blood stream. In addition to these conventional risk factors, new ones emerge as important factors for atherosclerosis, which include hyperhomocysteinemia, oxidative stress, and infectious agents. The results of the several ongoing trials of antibiotics, antioxidant, and vitamins for prevention of cardiovascular diseases will elucidate implications of these new risk factors for coronary atherosclerosis. The new insight on the pathogenesis of coronary atherosclerosis will change the preventive measures against cardiovascular events. We have to pay attention not only to the conventional measures such as reducing the cholesterol level, correcting hypertension, and prescribing anti-platelet agents, but also to the new measures such as reducing the homocysteine level by folate and vitamin B, encouraging intake of antioxidant in fresh vegetables and nuts, and eradicating infectious agents by oral care and ulcer treatment.
Anti-Bacterial Agents ; Atherosclerosis ; Cardiovascular Diseases ; Cholesterol ; Coronary Artery Disease* ; Coronary Vessels ; Diabetes Mellitus ; Folic Acid ; Homocysteine ; Hypercholesterolemia ; Hyperhomocysteinemia ; Hypertension ; Nuts ; Oxidative Stress ; Risk Factors ; Rivers ; Smoke ; Smoking ; Ulcer ; Vasodilation ; Vegetables ; Vitamins

Fabricating human organs with tissue engineering and stem cells may be an alternative to current suboptimal therapies for treatment of malfunction or loss of human tissues or organs. From the tissue engineering's perspective, the patients are expected to be treated with new tissues or organs reconstructed with transplanted cells. The cells for tissue engineering could be somatic cells derived from the patients themselves, other individuals, or animals. Another valuable cell source would be stem cells. Embryonic stem cells retain the pluripotency to differentiate into every cell type of human organs, but ethical issues remain to be addressed. Adult stem cells may solve these ethical issues and immune rejection, but have limitation in differentiation into all ranges of tissue-specific cell types. Tissue engineering typically employs scaffolds fabricated from synthetic or natural biomaterials to engineer a new functional tissue from cells. The configuration of the biomaterials guides the structure of a regenerated tissue by defining a three-dimensional space. Appropriate combination of tissue engineering with stem cells shows a promise to fabricate human organs or tissues that can be utilized for patients in the near future.
Adult Stem Cells ; Animals ; Artificial Organs ; Biocompatible Materials ; Embryonic Stem Cells ; Ethics ; Humans ; Stem Cells* ; Tissue Engineering*

Hemangiolymphangioma is a malformation of both lymphatic and blood vessels. While a hemangiolymphangioma is a benign lesion, its propensity to invade underlying tissues and to recur locally distinguishes it from the simple lymphangioma or hemangioma. Hemangiolymphangiomas are uncommon developmental anomalies and intraosseous hemangiolymphangioma of the mandible is a relatively rare condition: when it occurs, the clinical and radiographic presentation are often nonspecific. The author presents a case of hemangiolymphangioma in mandible.
Blood Vessels ; Hemangioma ; Lymphangioma ; Mandible*

No abstract available.
Genetic Predisposition to Disease*