Clinical survey was performed on 413 cases of twin pregnancies and their 816 twin babies who were born at IlSin Christian Hospital during 5years from January 1987 to December 1991. The result of study was as follows: 1) there was 413 twin pregnancies among 40,711 deliveries, so the incidence of twins was 1:98.6. Average male-female sex ratio of twins was 1.3:1, same sex pairs rate was 86% and different sex ratio was 14%. 2) The incidence of relation with maternal age was highest between 25 years old and 29 years old but the ratio of twin delivery to total delivery was 0.9% so, was not higher than other age group. 3) The incidence of relation with maternal parity was highest at first pregnancy but the ratio of twin delivery to total delivery was highest at second pregnancies. 4) Normal birth weight infants were 45.7%, low birth weight infants were 54.3% and very low birth weight infants was 9.3%. Fullt-erm infants were 63.7% and prematurity were 35.4%. 5) The incidence of feto-fetal transfusion was 7.3%. 6) Perinatal death rate was 76.3 and was more higher in second babies. The most common cause of perinatal death was prematurity, followed by respiratory complication, congenital anomaly, infection and asphyxia. Still-births were 8 cases.
Adult ; Asphyxia ; Birth Weight ; Female ; Humans ; Incidence ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; Infant, Very Low Birth Weight ; Maternal Age ; Mortality ; Parity ; Pregnancy ; Pregnancy, Twin ; Sex Ratio ; Twins*

This study was conducted to investigate the safety of the umbilical venous blood for antologous transfusion in the premature newborn babies. Umbilical venous blood was collected with aseptic technique immediately after delivery from 270 healthy mothers admitted to the Yeungnam University Hospital between March 1,1992 and August 31,1992 . The volume of the blood and the time taken for collecting the blood were measured. Also the hematological and biochemical changes of the blood during storage in the refrigerator of blood band and the incidence of bacterial contamination were studied. It took 67.6+/-25.9 seconds on the average for collecting the blood from an umbilical vein and the average volume of the blood was 77.1+/-23.2ml which would be sufficient volume for one time transfusion of 10ml/kg of packed red blood cells for the neonates. The hemoglobin and hematocrit values did not change significantly during storage for three weeks. Thus significant hemolysis did not seem to occur during storage. However, platelet counts decreased significantly from 248+/-59x10E3/mm3 to 193+/-47x10E3/mm3(p<0.01). Although plasma calcium level was not changed (8.4+/-0.9mg/dL), sodium was decreased significantly from 184.3+/-11.1mEq/L to 170.9+/-13.9mEq/L(p<0.01) and potassium was incresed from 5.0+/-1.0mEq/L to 26.7+/-4.8mEp/L.(p<0.01). Plasma glucose level was decreased from 521.7+/-106.7mg/dL to 294.3+/-120.8mg/dL (p<0.01), blood pH and bicarbonate concentrations were decreased significantly from 6.825+/-0.110 to 6.378+/-.087 and from 13.5+/-1.6mEq/L to 2.1+/-1.0mEq/L respectively (p<0.01). The smear of the umbilical venous blood and peripheral blood of the neonates stained by KleihauerBetke method revealed no significant differences in the percentages of adult red blood cells. Also there were no differences in the percentages of adult ted blood calls in the umbilical venous blood samples according to time for collection. The degree of decrement of hemoglobins (1.2gm/dL) after delivery in the mothers who had sampling of the umbilical venous blood was not different from that in the mothers who didn't hava sampling. The bacterial contamination rate of the umbilical venous blood was 3.5% (95% confidence interval was from 0.7 to 6.3). It seems to be safe to use the umbilical venous blood in the neonates for autologous transfusion but confirmation of bacterial contamination by culture is necessary.
Adult ; Blood Glucose ; Calcium ; Erythrocytes ; Hematocrit ; Hemolysis ; Humans ; Hydrogen-Ion Concentration ; Incidence ; Infant, Newborn* ; Mothers ; Plasma ; Platelet Count ; Potassium ; Sodium ; Umbilical Veins

No abstract available.
Child* ; Glomerulonephritis* ; Humans

BACKGROUND: An intensive and ongoing surveillance program is effective for preventing the hospital infections. but it is time-consuming to detect all cases of hospital infections. So, labratory-based surveillance was performed with the aid of personal computer. The software 'MICRO' that coded and used privately was written in FoxPro 2.0 code. METHODS: All results of the microbiologic culture were stocked in the software and hospital infections were detected by review d an positive microbiology reports and daily ward rounds with examination of patient progress notes. If there was any suggestion or evidence of outbreak of hospital infections the data were analyzed by the 'MICRO' and reported to hospital infections control committee. RESULTS: We detected the outbreak of nosoccmial pneumonia due to a putative single species of methicillin-resistant Staphylococcus aureus in the neurosurgical ward at May, 1996. The suggestive outbreak of wound infections in the 7th ward at April, 1966 was denied by the 'MICRO'. The possible outbreak of 10th ward at May, 1996 was detected. CONCLUSIONS: We describe a surveillance method that identifies excessive rates of positive culture on patient location culture site, and organism indentification using the 'MICRO'. We were able to monitor patient-to-patient cross-infections and possible breakdowns in proper technique, and expect suggestive outbreak of infections early. These results demonstrate that computer analysis of positive culture rates by 'MICRO' is a sensitive and time-efficient method for detecting potentially preventable hospital infections.
Cross Infection* ; Humans ; Methicillin-Resistant Staphylococcus aureus ; Microcomputers* ; Pneumonia ; Wound Infection

No abstract available.
Diabetes Insipidus* ; Diagnosis*

Neonatal and obstetrical problems related to the low birth weight infants were evaluated by a retrospective review of the medical records of the 186 low birth weight infants born at Yeungnam University Hospital during 3 years and 8 months from May 1, 1983 to February 28, 1987. The results were as follows: 1. The incidence of the low birth weight infants was 4.98% among 3,803 live births. 2. Male to female ratio was 1.02:1. 3. The incidence of the low birth weight infants was lowest in mothers of 25 to 29 years, increased in mothers of 19 years of less and 30 to 39 years significantly. 4. There was no difference in the incidence of low birth weight infants between primiparous and multiparous mothers. 5. Common obstetrical complications associated with low weight infants were multiple pregnancy, toxemia and premature rupture of membrane in order of frequency. 6. Common neonatal problems in low birth weight infants were jaundice, idiopathic respiratory, distress syndrome, asphyxia and metabolic derangement such as hypocalcemia and hypoglycemia in order of frequency.
Asphyxia ; Clinical Study* ; Female ; Humans ; Hypocalcemia ; Hypoglycemia ; Incidence ; Infant* ; Infant, Low Birth Weight* ; Infant, Newborn ; Jaundice ; Live Birth ; Male ; Medical Records ; Membranes ; Mothers ; Pregnancy ; Pregnancy, Multiple ; Retrospective Studies ; Rupture ; Toxemia

A 24-year-old woman was seen for evaluation of an skin lesion on thiright nipple. Examination revealed a solitary 1.5 x 1cm-sized, erythematous, oozing, eroded andruted, verrucous nodule on the right nipple. A small amount of serous discharge was found but there was no pain or tenderness. Histopathologic findings showed cystic invaginations extending down vard from the epidermis and papillary projections extending into the lumina of the invagination. Pupiae were lined by two rows of cells. In stroma, there were marked inflammatory infiltrates containing any plasma cells. The overlying dermis showed an adenomatous growth pattern with a prolifertion of round, oval or irregular shaped ducts and fibrotic stroma.
Adenoma* ; Cytochrome P-450 CYP1A1 ; Dermis ; Epidermis ; Female ; Humans ; Nipples* ; Plasma Cells ; Skin ; Young Adult

Barts syndrome was desrribed by Bart(Bart et al, 1966) with hereditary congenital localized absence of skin from the lovrer legs associated with blistering of the sun and mouth and nail abnormalities. A newborn girl presented with a congenital localized absence of skn over both shins & dorsa of both feet which were covered with the thin, translucent, brown red glistening membranes. A number of blisters were seen on the back, thighs upper extremities, and both 2rd toe nails were absent. Electron microscopic examination of defected skin revealed dermo-epidermal . paration with focal disruption of basal lamina.
Basement Membrane ; Blister ; Female ; Foot ; Humans ; Infant, Newborn ; Leg ; Membranes ; Mouth ; Nails, Malformed ; Skin ; Solar System ; Thigh ; Toes ; Upper Extremity

No abstract available.
Hallermann's Syndrome*

No abstract available.
Fever ; Humans ; Still's Disease, Adult-Onset* ; Urticaria*