No abstract available.

BACKGROUND: The elastic fiber network undergoes profound alterations during the ageing process. OBJECTIVE: Our study compared two type ageing process of elastic fiber; the first, age associated, is found in skin from a nonexposed area; the second, related to sun exposure, is found in an exposed area. METHODS: In order to differentiate these two forms of ageing process, the author tried to compare length, breadth, perimeter, shape factor and amount of elastic fiber between the exposed and nonexposed skin of 240 Korean men using computerized digital image analysis system. RESULTS: Amount and breadth of elastic fibers are significantly different between exposed and nonexposed area in the same age group. After the fifties, the length of each elastic fiber in exposed areas are significantly longer than those of nonexposed area. Breadth is more sensitive than length to photoageing. The amount of elastic fiber is variable in nonexposed areas but increased steadily according to age in exposed areas. CONCLUSION: The amount and four morphological factors of elastic fiber show there are significant differences between photoageing and chronological ageing process.
Elastic Tissue* ; Humans* ; Male ; Skin* ; Solar System

No abstract available.

No abstract available.
Euonymus*

No abstract available.
Axis, Cervical Vertebra* ; Dislocations* ; Patella*

BACKGROUND: The principle of Mohs micrographic surgery is to examine microscopically the entire peripheral margin of an excised tissue specimen to precisely localize the site of any residual tumor and enable its subsequent removal. In processing in the tissue for frozen horizontal sections, a technical difficulty arises in manipulating the deep and lateral margins into the same flat plane. OBJECTIVE: Our aim was to develop a new method allowing the optimal tissue preperation for Mohs micrographic smgery and to evaluate the usefulness of this methad. METHODS: The technique involves conversion of a non-planar surgical margin to a planar surface by applying and freezing the specimen against a flat glass surface. We compared this modified method used in our laboratory with standard methods for tissue preparation of Mohs micrographic surgery.
Freezing ; Glass ; Mohs Surgery ; Neoplasm, Residual

Antibiotic-acrylic bone cement composites demonstrated antibacterial activity as a result of diffusion of antibiotic from bone cement into surrounding enviroment, accordingly, the use of antibiotic incorporation to bone cement for the prevention and treatment of infection after joint surgery replacement has been adovocated. Early report of clinical success by using antibiotic-acrylic bone cement composites are encouraging. Our authors applied this concept to the treatment of chronic osteomyelitis. Antibiotic contained with bone cement was chosen by sensitivity test on pus culture finding. Seven cases of chronic osteomyelitia treated by using antibiotic-acrylic bone eement composites were .studied in the Department of Orthopaedic Surgery, Kyung Hee University Hospital from July 1979 to March 1981. The follow-up period was from 3 months tc 22 months. The results were as follow: 1. Six cases showed no evidence of recurrence except one by using antibiotic acrylic bone cement composites. 2. The impregantion of antibiotic in acrylic bone cement shall be regarded to be effective in increasing the local antibacterial activity by leaching the antibiotic into surrounding tissue over a period continiously in treatment of chronic osteomyelitis. 3. The use of antibiotic-acrylic bone cement compositea into dead space by saucerization are consid- ered an one such approach to the decrease of dead space. 4. The impregnation of antibiotic in acrylic bone cement is regarded a new concept in treatment of chronic osteomyelitis.
Bone and Bones ; Diffusion ; Follow-Up Studies ; Joints ; Osteomyelitis ; Polymethyl Methacrylate ; Recurrence ; Suppuration

BACKGROUND: With the development of medical science and technology, the proprotion of the aged has been significantly increasecl. Therefore it needs to be studied the fuadamental epidemiologic survey of dermatologic diseases and akin care in the elderly. OBJECT: Our purpose was to provide clinically relevant data regaring both dermatologic diseases and skin care in the aged population. MEHTODS: Total 172 volunteers aged 51 to 90 were enrolled in a study of 32-item questionnaire and total cutaneous examination. RESULTS: The sex ratio of male to female of 172 elderly volunteers as 1:1.4 and population of 7th and 8th decades occupied 76.5% with their mean age 74.4. The dermatologic findings which showed higher incidence in this study were seborrheic keratosis, senile lentigines, xerosis, cherry angioma, and generalized pruritus. Through the interviews of 172 elderly, the mot fequent dermatologic complaint was generalized pruritus. As the mean age of the population increasec, the number of the population showing xerosis and complaing of pruritus was elevated(r=0.976. 0.917 respectively). And there was a significant stastical correlation between the finding of xerosis and the the presence of pruritus(P<0.005). CONCLUSION: This study suggests that dermatologic problems in the elilerly are very common ancl further dermatologic studies including substantial medical care will be needed.
Aged ; Epidemiology ; Female ; Hemangioma ; Humans ; Incidence ; Keratosis, Seborrheic ; Lentigo ; Male ; Prunus ; Pruritus ; Sex Ratio ; Skin Care* ; Skin Diseases* ; Skin* ; Volunteers

Helicobacter pylori infection has been shown to be associated with gastric carcinoma. However, despite the frequent detection of seropositivity for H. pylori and histologic detection in biopsy specimen, histologic detection rate of H. pylori in surgical specimens has been low. In this study, we investigated the prevalence of H. pylori infection in gastrectomy specimens bearing gastric adenocarcinoma and compared it with both endoscopic biopsy and serologic results. H. pylori infection was identified by Giemsa stain in the mucosa stripped from the tumor, body, and antrum in 61 gastrectomy specimens. We evaluated the effect of H. pylori infection on gastric mucosal cell proliferation by using monoclonal antibody for Ki-67. H. pylori detection rate using Giemsa stain was higher in gastrectomy specimens (67.3%) compared to that (48.1%) of biopsy specimens (p=0.006). The detection rate was higher in body than that of antrum or tumor site in the same patients (p=0.001). The H. pylori seropositivity was 60.5% and relatively nonspecific. The mean value of Ki-67 labeling index in the H. pylori-positive group was higher than that in the H. pylori-negative group (p<0.05). The increase in gastric epithelial cell proliferation was not influenced by the location of the tumor or the site of the specimen. The results suggest that the actual prevalence of H. pylori infection in patients with gastric carcinoma is considerably higher than that evaluated on endoscopic biopsy specimens. In addition, the increased cell proliferation in the H. pylori-positive group suggests some evidence that H. pylori may be involved in gastric carcinogenesis.
Adenocarcinoma* ; Azure Stains ; Biopsy ; Carcinogenesis ; Cell Proliferation ; Epithelial Cells ; Epithelium* ; Gastrectomy ; Helicobacter pylori* ; Helicobacter* ; Humans ; Mucous Membrane ; Prevalence

BACKGROUND: The confgurations of the skin surface, as characterized by surface furrows and plateaux, are known to change with ageing. There are many parameters to analyze the effects of ageing processes on the surface configuration. However, there are contradictory results among the authors. OBJECTIVE: The purpose of this study was to compare the sensitivity of various parameters being described in other reports with our new parameters used in evaluating the changes of the skin surface in the agein processes. METHODS: 112 healthy Korean males in 4 age groups participated in this study. Silicon skin replicas were taken from medial and lateral aspects of the forearm. Images of the skin replicas were analyzed by means of a digital image processing system (AIC, GA). Most parameters were calculated and measured in the primary skin axis. Image analyses were porformed by 3 different processes i.e., morphometry, densitometry (optical profilometry), and histograms. RESULTS: In Morphometry, the furrow count in the vertical section (VFC), the coefficient of the developed skin surface (CDSS) and mean width at maximal interception (MWMI) showed a tendencies to decrease with ageing.Irregularity of shadow shape (ISS) showed a tendency to increase with ageing. In Densitometry, the mean surface roughness(Ra) and mean depth of roughness(Rz) showed a tendency to increase with ageing. On histogram analysis, skewness was decreased with ageing but kurtosis did not show any significant changes. CONCLUSION:Ra, Rz, and ISS have shown a tendency to increase in the ageing processes (p<0. 05). VFC, CDSS, MWMI and skewness showed tendencies to decrease with ageing but the results were not statistically significant. The different results between morphometry and densitometry are likely to be due to increrr ent angles in the skin furrows with ageing.
Axis, Cervical Vertebra ; Densitometry ; Forearm ; Humans ; Male ; Silicones ; Skin*